M. Rubin

C. F. Mello, M. Rubin, C. K. Konopka, 2013, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

Intrastriatal malonate administration induces convulsive behaviour in rats

C. F. Mello, V. Sinhorin, M. Rubin, 2004, Journal of Inherited Metabolic Disease.

Antinociceptive effect of novel pyrazolines in mice.

N. Zanatta, M. Martins, C. F. Mello, 2004, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

Extending the analysis of zebrafish behavioral endophenotypes for modeling psychiatric disorders: Fear conditioning to conspecific alarm response

Barbara D. Fontana, J. Rocha, C. Maximino, 2018, Behavioural Processes.

N-Acetylcysteine prevents baker’s-yeast-induced inflammation and fever

C. F. Mello, A. P. O. Ferreira, J. Ferreira, 2011, Inflammation Research.

Neurochemical effects ofl-pyroglutamic acid

D. Souza, M. Wajner, C. F. Mello, 1995, Neurochemical Research.

Neuroprotective effects of berberine on recognition memory impairment, oxidative stress, and damage to the purinergic system in rats submitted to intracerebroventricular injection of streptozotocin

J. Baldissarelli, C. M. de Andrade, F. H. Abdalla, 2018, Psychopharmacology.

The potential antidepressant-like effect of imidazoline I2 ligand 2-BFI in mice

M. Martins, J. Ferreira, G. Trevisan, 2012, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Behavior and brain enzymatic changes after long-term intoxication with cadmium salt or contaminated potatoes.

V. Dressler, V. Morsch, F. Nicoloso, 2012, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

N-acetylcysteine prevents memory deficits, the decrease in acetylcholinesterase activity and oxidative stress in rats exposed to cadmium.

V. Dressler, V. Morsch, F. G. Antes, 2010, Chemico-biological interactions.

Antinociceptive effects of 14-membered cyclopeptide alkaloids.

A. Morel, J. Ferreira, G. Trevisan, 2009, Journal of natural products.

Effect of morphine on the persistence of long-term memory in rats

C. F. Mello, L. Milanesi, M. Rubin, 2015, Psychopharmacology.

Design and microwave-assisted synthesis of 5-trifluoromethyl-4,5-dihydro-1H-pyrazoles: novel agents with analgesic and anti-inflammatory properties.

N. Zanatta, R. Burrow, A. H. de Souza, 2008, European journal of medicinal chemistry.

A pyrazolyl-thiazole derivative causes antinociception in mice.

N. Zanatta, R. Lourega, A. H. de Souza, 2006, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

A novel, potent, oral active and safe antinociceptive pyrazole targeting kappa opioid receptors

N. Zanatta, J. Calixto, A. Boligon, 2013, Neuropharmacology.

Effect of 5-trifluoromethyl-4,5-dihydro-1H-pyrazoles on chronic inflammatory pain model in rats.

N. Zanatta, M. Martins, C. F. Mello, 2009, European journal of pharmacology.

Antinociceptive effect of a novel tosylpyrazole compound in mice.

N. Zanatta, R. Lourega, S. M. Oliveira, 2009, Basic & clinical pharmacology & toxicology.

Antinociceptive action of 4-methyl-5-trifluoromethyl-5-hydroxy-4, 5-dihydro-1H-pyrazole methyl ester in models of inflammatory pain in mice.

N. Zanatta, C. Drewes, S. M. Oliveira, 2008, Life sciences.

Alpha 2-adrenoceptors and 5-HT receptors mediate the antinociceptive effect of new pyrazolines, but not of dipyrone.

N. Zanatta, M. Martins, M. R. Fighera, 2004, European journal of pharmacology.

Spermine protects from LPS-induced memory deficit via BDNF and TrkB activation

H. Ulrich, M. Pillat, C. F. Mello, 2018, Neurobiology of Learning and Memory.

Modulation of learning and memory by natural polyamines.

C. F. Mello, M. Rubin, G. P. Guerra, 2016, Pharmacological research.

Hippocampal PKA/CREB pathway is involved in the improvement of memory induced by spermidine in rats

J. Calixto, G. Bochi, C. F. Mello, 2011, Neurobiology of Learning and Memory.

Spermidine-induced improvement of reconsolidation of memory involves calcium-dependent protein kinase in rats

C. F. Mello, M. Rubin, Cristiane Signor, 2016, Learning & memory.

Spermidine‐induced improvement of memory involves a cross‐talk between protein kinases C and A

J. Ferreira, M. Rubin, A. M. Pazini, 2012, Journal of neurochemistry.

Inhibitory effect of Scutia buxifolia extracts, fractions, and ursolic acid on Na(+), K(+)-ATPase activity in vitro in membranes purified from rat hearts.

A. Boligon, F. Carvalho, J. Ferreira, 2016, Journal of ethnopharmacology.

Guarana (Paullinia cupana) ameliorates memory impairment and modulates acetylcholinesterase activity in Poloxamer-407-induced hyperlipidemia in rat brain

F. H. Abdalla, Stephen Adeniyi Adefegha, D. Leal, 2017, Physiology & Behavior.

Ebselen blocks the quinolinic acid-induced production of thiobarbituric acid reactive species but does not prevent the behavioral alterations produced by intra-striatal quinolinic acid administration in the rat

J. I. Rossato, J. Rocha, C. F. Mello, 2002, Neuroscience Letters.

Diminished concentration of the NF-H subunit of neurofilaments in cerebral cortex of rats chronically treated with proline, methylmalonate and phenylalanine plus α-methylphenylalanine

C. Wannmacher, M. Rubin, R. P. Pureur, 1992, Journal of Inherited Metabolic Disease.

Mansoa alliacea extract presents antinociceptive effect in a chronic inflammatory pain model in mice through opioid mechanisms

L. M. de Carvalho, S. M. Oliveira, Indiara Brusco, 2019, Neurochemistry International.

Resveratrol prevents memory deficits and the increase in acetylcholinesterase activity in streptozotocin-induced diabetic rats.

V. Morsch, C. Mazzanti, M. Corrêa, 2009, European journal of pharmacology.

Spermidine-induced improvement of memory consolidation involves PI3K/Akt signaling pathway

M. Pillat, C. F. Mello, M. Rubin, 2020, Brain Research Bulletin.

Spermidine improves the persistence of reconsolidated fear memory and neural differentiation in vitro: Involvement of BDNF

H. Ulrich, M. Pillat, C. F. Mello, 2017, Neurobiology of Learning and Memory.

Berberine protects against memory impairment and anxiogenic-like behavior in rats submitted to sporadic Alzheimer's-like dementia: Involvement of acetylcholinesterase and cell death.

M. Pillat, J. Baldissarelli, C. M. de Andrade, 2016, Neurotoxicology.

Intrahippocampal infusion of spermidine improves memory persistence: Involvement of protein kinase A

V. Funck, Mauro S. Oliveira, C. F. Mello, 2016, Neurobiology of Learning and Memory.

GM1 ganglioside induces vasodilation and increases catalase content in the brain.

M. R. Fighera, L. Royes, A. F. Furian, 2007, Free radical biology & medicine.

Antidepressant-like effect of the novel MAO inhibitor 2-(3,4-dimethoxy-phenyl)-4,5-dihydro-1H-imidazole (2-DMPI) in mice

C. Cunha, P. Dombrowski, N. Zanatta, 2012, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Antinociceptive and antidepressant-like effects of the crude extract of Vitex megapotamica in rats.

L. M. de Carvalho, S. M. Oliveira, C. F. Mello, 2016, Journal of ethnopharmacology.

Spermidine decreases Na⁺,K⁺-ATPase activity through NMDA receptor and protein kinase G activation in the hippocampus of rats.

Mauro S. Oliveira, C. F. Mello, F. Carvalho, 2012, European journal of pharmacology.

Arcaine and MK-801 make recall state-dependent in rats

C. F. Mello, M. Rubin, Ana Paula Chiapinotto Ceretta, 2008, Psychopharmacology.

The involvement of the polyamines binding sites at the NMDA receptor in creatine-induced spatial learning enhancement

Carlos Fernando Mello, M. R. Fighera, L. Royes, 2008, Behavioural Brain Research.

Nitric oxide is involved in the memory facilitation induced by spermidine in rats

A. F. Furian, C. F. Mello, M. Rubin, 2006, Psychopharmacology.

Protective effects of anthocyanins on the ectonucleotidase activity in the impairment of memory induced by scopolamine in adult rats.

M. Schetinger, F. Carvalho, C. Mazzanti, 2012, Life sciences.

Quercetin protects the impairment of memory and anxiogenic-like behavior in rats exposed to cadmium: Possible involvement of the acetylcholinesterase and Na+,K+-ATPase activities

V. Dressler, J. Baldissarelli, V. Morsch, 2014, Physiology & Behavior.

Succinate increases neuronal post-synaptic excitatory potentials in vitro and induces convulsive behavior through N-methyl-d-aspartate-mediated mechanisms

E. Cavalheiro, E. Garrido-Sanabria, C. F. Mello, 2004, Neuroscience.

d,l-cis-2,3-Pyrrolidine dicarboxylate alters [3H]-l-glutamate binding and induces convulsions in mice

C. R. Correia, C. F. Mello, V. Sinhorin, 2003, Pharmacology Biochemistry and Behavior.

Spermine improves recognition memory deficit in a rodent model of Huntington’s disease

C. F. Mello, M. Rubin, R. Cunha, 2009, Neurobiology of Learning and Memory.

Curcumin attenuates memory deficits and the impairment of cholinergic and purinergic signaling in rats chronically exposed to cadmium

J. Baldissarelli, V. Morsch, M. Schetinger, 2017, Environmental toxicology.

Protective effect of α-Tocopherol on memory deficits and Na+,K+-ATPase and acetylcholinesterase activities in rats with diet-induced hypercholesterolemia

V. Morsch, M. Schetinger, F. Carvalho, 2012 .

Effects of chlorogenic acid, caffeine, and coffee on behavioral and biochemical parameters of diabetic rats

S. Passamonti, V. Morsch, A. Cardoso, 2013, Molecular and Cellular Biochemistry.

Hypoxia–Ischemia Alters Nucleotide and Nucleoside Catabolism and Na+,K+-ATPase Activity in the Cerebral Cortex of Newborn Rats

V. Morsch, M. Bagatini, D. Zanini, 2013, Neurochemical Research.

Free and nanoencapsulated curcumin prevents cigarette smoke-induced cognitive impairment and redox imbalance

R. Beck, M. Schetinger, F. Carvalho, 2013, Neurobiology of Learning and Memory.

Caffeine prevents high-intensity exercise-induced increase in enzymatic antioxidant and Na+-K+-ATPase activities and reduction of anxiolytic like-behaviour in rats

V. Morsch, M. Schetinger, F. Carvalho, 2017, Redox report : communications in free radical research.

Neuroprotective effects of quercetin on memory and anxiogenic-like behavior in diabetic rats: Role of ectonucleotidases and acetylcholinesterase activities.

V. Morsch, D. Zanini, C. Danesi, 2016, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Anxiolytic-like effects of 4-phenyl-2-trichloromethyl-3H-1, 5-benzodiazepine hydrogen sulfate in mice.

C. Queiroz, C. F. Mello, H. Bonacorso, 2000, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

Polyaminergic agents modulate the reconsolidation of conditioned fear

C. F. Mello, M. Rubin, Cristiane Signor, 2013, Neurobiology of Learning and Memory.

Opioid mechanisms are involved in the disruption of arcaine-induced amnesia by context pre-exposure

C. F. Mello, M. Rubin, Cristiane Signor, 2012, Neurobiology of Learning and Memory.

Neuroprotective effects of pretreatment with quercetin as assessed by acetylcholinesterase assay and behavioral testing in poloxamer-407 induced hyperlipidemic rats.

C. M. de Andrade, G. L. Dornelles, Stephen Adeniyi Adefegha, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Piracetam Prevents Scopolamine-Induced Memory Impairment and Decrease of NTPDase, 5′-Nucleotidase and Adenosine Deaminase Activities

M. Schetinger, C. F. Mello, F. Carvalho, 2013, Neurochemical Research.

GM1 ganglioside attenuates convulsions and thiobarbituric acid reactive substances production induced by the intrastriatal injection of methylmalonic acid.

J. Bonini, J. Rocha, C. Dutra-filho, 2003, The international journal of biochemistry & cell biology.

Inhibition of the Polyamine System Counteracts β-Amyloid Peptide-Induced Memory Impairment in Mice: Involvement of Extrasynaptic NMDA Receptors

M. Kreutz, A. Karpova, C. F. Mello, 2014, PloS one.

Effect of vitamin D3 on behavioural and biochemical parameters in diabetes type 1‐induced rats

V. Morsch, M. Schetinger, F. Carvalho, 2014, Cell biochemistry and function.

Effect of lead acetate on neurobehavioral development of rats.

A. Martins, V. Morsch, C. F. Mello, 1998, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

Piracetam Prevents Scopolamine-Induced Memory Impairment and Decrease of NTPDase, 5′-Nucleotidase and Adenosine Deaminase Activities

M. Schetinger, C. F. Mello, F. Carvalho, 2013, Neurochemical Research.

Bradykinin into amygdala induces thermal hyperalgesia in rats

J. Calixto, C. F. Mello, J. Ferreira, 2007, Neuropeptides.

Spermidine, a positive modulator of the NMDA receptor, facilitates extinction and prevents the reinstatement of morphine-induced conditioned place preference in mice

C. F. Mello, M. Rubin, A. L. Wendel, 2019, Psychopharmacology.

Spermidine improves fear memory persistence.

C. F. Mello, M. Rubin, Cristiane Signor, 2014, European journal of pharmacology.

Spermine reverses lipopolysaccharide-induced memory deficit in mice

C. F. Mello, T. Duarte, M. Rubin, 2015, Journal of Neuroinflammation.

Intra-Amygdala Administration of Polyamines Modulates Fear Conditioning in Rats

C. F. Mello, M. Rubin, J. A. Stiegemeier, 2004, The Journal of Neuroscience.

Difluoromethylornithine (DFMO) reduces deficits in isolation-induced ultrasonic vocalizations and balance following neonatal ethanol exposure in rats

J. Littleton, M. Rubin, B. Lewis, 2009, Pharmacology Biochemistry and Behavior.

Effect of naloxone and morphine on arcaine-induced state-dependent memory in rats

C. F. Mello, M. Rubin, Ana Paula Chiapinotto Ceretta, 2011, Psychopharmacology.

Intrastriatal Methylmalonic Acid Administration Induces Convulsions and TBARS Production, and Alters Na+,K+‐ATPase Activity in the Rat Striatum and Cerebral Cortex

E. Cavalheiro, L. Royes, C. F. Mello, 2003, Epilepsia.

A Nonrewarding NMDA Receptor Antagonist Impairs the Acquisition, Consolidation, and Expression of Morphine Conditioned Place Preference in Mice

C. F. Mello, M. Rubin, P. K. S. Frühauf, 2016, Molecular Neurobiology.

Traxoprodil decreases pentylenetetrazol-induced seizures

A. F. Furian, Mauro S. Oliveira, C. F. Mello, 2012, Epilepsy Research.

Polyaminergic agents modulate contextual fear extinction in rats

G. Bochi, C. F. Mello, J. Ferreira, 2010, Neurobiology of Learning and Memory.

Systemic administration of polyaminergic agents modulate fear conditioning in rats

C. F. Mello, M. Rubin, Ana Paula Chiapinotto Ceretta, 2007, Psychopharmacology.

Effects of Lead on Adenylate Cyclase Activity in Rat Cerebral Cortex

D. Souza, A. Rodrigues, A. Regner, 1999, Neurochemical Research.

Spermidine, a positive modulator of the NMDA receptor, facilitates extinction and prevents the reinstatement of morphine-induced conditioned place preference in mice

C. F. Mello, M. Rubin, A. L. Wendel, 2019, Psychopharmacology.

The selective A-type K+ current blocker Tx3-1 isolated from the Phoneutria nigriventer venom enhances memory of naïve and Aβ(25-35)-treated mice.

J. Ferreira, M. N. Cordeiro, M. Rubin, 2013, Toxicon : official journal of the International Society on Toxinology.

Selegiline Reverses Aβ25–35-Induced Cognitive Deficit in Male Mice

C. Cunha, C. F. Mello, A. P. O. Ferreira, 2013, Neurochemical Research.

Ultrasound Promoted Synthesis of 2‐Imidazolines in Water: A Greener Approach Toward Monoamine Oxidase Inhibitors.

N. Zanatta, M. Martins, J. Ferreira, 2009 .

Hypoxia–Ischemia Alters Nucleotide and Nucleoside Catabolism and Na+,K+-ATPase Activity in the Cerebral Cortex of Newborn Rats

V. Morsch, M. Bagatini, M. Schetinger, 2013, Neurochemical Research.

Malnutrition increases insoluble-to-soluble tubulin ratio and in vitro incorporation of 32ATP in rat cerebral cortex

R. Pessoa-Pureur, C. Tasca, M. Rubin, 1992, Neurochemistry International.

Effects of chlorogenic acid, caffeine, and coffee on behavioral and biochemical parameters of diabetic rats

S. Passamonti, V. Morsch, J. Rocha, 2014, Molecular and Cellular Biochemistry.

N-Acetylcysteine prevents baker’s-yeast-induced inflammation and fever

C. F. Mello, A. P. O. Ferreira, J. Ferreira, 2012, Inflammation Research.

Curcumin protects against cigarette smoke-induced cognitive impairment and increased acetylcholinesterase activity in rats

M. Schetinger, F. Carvalho, C. Mazzanti, 2012, Physiology & Behavior.

Lead exposure and latent learning ability of adult female rats.

D. Souza, A. Rodrigues, C. F. Mello, 1993, Behavioral and neural biology.

Assessing the exploratory profile of two zebrafish populations: Influence of anxiety-like phenotypes and independent trials on homebase-related parameters and exploration

D. Rosemberg, João V. Borba, M. Rubin, 2023, Behavioural Processes.

Antinociceptive effects of Cremophor EL orally administered to mice.

C. F. Mello, M. Rubin, P. D. Sauzem, 2003, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

Neuroprotective effects of berberine on recognition memory impairment, oxidative stress, and damage to the purinergic system in rats submitted to intracerebroventricular injection of streptozotocin

J. Baldissarelli, C. M. de Andrade, G. L. Dornelles, 2018, Psychopharmacology.

Effect of vitamin D3 on behavioural and biochemical parameters in diabetes type 1‐induced rats

V. Morsch, M. Schetinger, F. Carvalho, 2014, Cell biochemistry and function.

Free and nanoencapsulated curcumin prevents cigarette smoke-induced cognitive impairment and redox imbalance

R. Beck, M. Schetinger, F. Carvalho, 2013, Neurobiology of Learning and Memory.

Spermidine decreases Na⁺,K⁺-ATPase activity through NMDA receptor and protein kinase G activation in the hippocampus of rats.

Mauro S. Oliveira, C. F. Mello, F. Carvalho, 2012, European journal of pharmacology.

Effect of morphine on the persistence of long-term memory in rats

C. F. Mello, L. Milanesi, M. Rubin, 2014, Psychopharmacology.

Resveratrol prevents memory deficits and the increase in acetylcholinesterase activity in streptozotocin-induced diabetic rats.

V. Morsch, C. Mazzanti, M. Corrêa, 2009, European journal of pharmacology.

Spermine improves recognition memory deficit in a rodent model of Huntington’s disease

C. F. Mello, M. Rubin, R. Cunha, 2009, Neurobiology of Learning and Memory.

Diphenyl diselenide supplementation in infected mice by Toxoplasma gondii: Protective effect on behavior, neuromodulation and oxidative stress caused by disease.

M. Baldissera, V. Morsch, M. Schetinger, 2016, Experimental parasitology.

CaMKIIα mediates spermidine-induced memory enhancement in rats: A potential involvement of PKA/CREB pathway

M. Prigol, M. Rubin, G. P. Guerra, 2024, Pharmacology Biochemistry and Behavior.