A. Denda

H. Kuniyasu, T. Kirita, K. Yamamoto, 2004, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

Inhibitory effects of selective cyclooxygenase-2 inhibitors, nimesulide and etodolac, on the development of squamous cell dysplasias and carcinomas of the tongue in rats initiated with 4-nitroquinoline 1-oxide.

H. Kuniyasu, T. Kirita, A. Denda, 2003, Cancer letters.

Chemopreventive effects of nimesulide, a selective cyclooxygenase-2 inhibitor, on the development of rat urinary bladder carcinomas initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine.

K. Wakabayashi, E. Okajima, Y. Konishi, 1998, Cancer research.

Diabetes-associated angiotensin activation enhances liver metastasis of colon cancer

Yi Luo, T. Sasahira, H. Kuniyasu, 2012, Clinical & Experimental Metastasis.

Inhibition by phenyl N-tert-butyl nitrone of early phase carcinogenesis in the livers of rats fed a choline-deficient, L-amino acid-defined diet.

K. Hensley, Y. Kotake, H. Sang, 1998, Cancer research.

Effect of dose on the carcinogenic activity of orally administered N-bis(2-hydroxypropyl)nitrosamine in rats.

Y. Konishi, A. Denda, A. Kawabata, 1978, Gan.

Chemopreventive Efficacy of Piroxicam Administered Alone or in Combination with Lycopene and β‐Carotene on the Development of Rat Urinary Bladder Carcinoma after A N‐Butyl‐N‐(4‐hydroxybutyl)nitrosamine Treatment

E. Okajima, Y. Konishi, M. Tsutsumi, 1997, Japanese journal of cancer research : Gann.

Dietary Linoleic Acid and Glucose Enhances Azoxymethane-Induced Colon Cancer and Metastases via the Expression of High-Mobility Group Box 1

Yi Luo, T. Sasahira, H. Kuniyasu, 2010, Pathobiology.

Development of Hepatocellular Adenomas and Carcinomas Associated with Fibrosis in C57BL/6J Male Mice Given a Choline‐deficient, L‐Amino Acid‐defined Diet

Y. Konishi, D. Nakae, M. Tsutsumi, 2002, Japanese journal of cancer research : Gann.

Genetic properties for the suppression of development of putative preneoplastic glutathione S-transferase placental form-positive foci in the liver of carcinogen-resistant DRH strain rats.

K. Higashi, Y. Fukamachi, T. Abe, 1999, Cancer letters.

Prevention by acetylsalicylic acid of liver cirrhosis and carcinogenesis as well as generations of 8-hydroxydeoxyguanosine and thiobarbituric acid-reactive substances caused by a choline-deficient, L-amino acid-defined diet in rats.

Y. Konishi, D. Nakae, Q. Tang, 1994, Carcinogenesis.

4-Hydroxyaminoquinoline 1-oxide metabolism and DNA adducts in the early stage of tumorigenesis in rats: comparison of target organ pancreas with non-target organ liver.

M. Tsutsumi, Y. Konishi, A. Denda, 1985, Chemico-biological interactions.

Inhibitory effect of linoleic acid on transformation of IEC6 intestinal cells by in vitro azoxymethane treatment

Kazuhiro Yoshida, T. Sasahira, H. Kuniyasu, 2006, International journal of cancer.

Inhibition of Early‐phase Exogenous and Endogenous Liver Carcinogenesis in Transgenic Rats Harboring a Rat Glutathione S‐Transferase Placental Form Gene

Y. Konishi, D. Nakae, M. Muramatsu, 1998, Japanese journal of cancer research : Gann.

Increased expression of cyclooxygenase-2 protein in rat lung tumors induced by N-nitrosobis(2-hydroxypropyl)amine.

Y. Konishi, M. Tsutsumi, T. Tsujiuchi, 2000, Cancer letters.

Increased expression of cyclooxygenase-2 protein in rat urinary bladder tumors induced by N-butyl-N-(4-hydroxybutyl) nitrosamine.

E. Okajima, Y. Konishi, T. Tsujiuchi, 1999, Carcinogenesis.

Inhibitory Effects of Inhibitors of Arachidonic Acid Metabolism on the Evolution of Rat Liver Preneoplastic Foci into Nodules and Hepatocellular Carcinomas with or without Phenobarbital Exposure

Y. Konishi, M. Tsutsumi, T. Tsujiuchi, 1993, Japanese journal of cancer research : Gann.

Enhancing effect of 3-aminobenzamide on induction of gamma-glutamyl transpeptidase positive foci in rat liver.

T. Ohnishi, Y. Konishi, A. Denda, 1982, Chemico-biological interactions.

Increased expression of cyclooxygenase-2 protein during rat hepatocarcinogenesis caused by a choline-deficient, L-amino acid-defined diet and chemopreventive efficacy of a specific inhibitor, nimesulide.

Y. Konishi, D. Nakae, M. Tsutsumi, 2002, Carcinogenesis.

Enhancement of hepatocarcinogenesis initiated with diethylnitrosamine or N-nitrosobis(2-hydroxypropyl)amine by a choline-deficient, L-amino acid-defined diet administered prior to the carcinogen exposure in rats.

Y. Konishi, D. Nakae, A. Denda, 2000, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

Effects of oxidative stress induced by redox-enzyme modulation on rat hepatocarcinogenesis.

Y. Konishi, D. Nakae, A. Denda, 1995, Toxicology letters.

Interleukin-15 Expression Is Associated with Malignant Potential in Colon Cancer Cells

H. Yokozaki, H. Kuniyasu, N. Oue, 2001, Pathobiology.

Induction of telomerase activity during regeneration after partial hepatectomy in the rat.

Y. Konishi, M. Tsutsumi, H. Sakitani, 1998, Cancer letters.

Increased Telomerase Activity in Hyperplastic Nodules and Hepatocellular Carcinomas Induced by a Choline‐deficient L‐Amino Acid‐defined Diet in Rats

Y. Konishi, D. Nakae, M. Tsutsumi, 1996, Japanese journal of cancer research : Gann.

RISK EVALUATION OF ACETAMINOPHEN IN PRE-EXISTING FATTY LIVER INDUCED BY CHOLINE-DEVOID DIET ON LIVER CARCINOGENESIS IN MALE F344 RATS

Y. Konishi, D. Nakae, M. Tsutsumi, 1990 .

Production of Both 8‐Hydroxydeoxyguanosine in Liver DNA and γ‐Glutamyltransferase‐positive Hepatocellular Lesions in Rats Given a Choline‐deficient, l‐Amino Acid‐defined Diet

H. Yoshiji, Y. Konishi, D. Nakae, 1990, Japanese journal of cancer research : Gann.

Co‐treatment with deoxycholic acid and azoxymethane accelerates secretion of HMGB1 in IEC6 intestinal epithelial cells

T. Sasahira, H. Kuniyasu, H. Ohmori, 2009, Cell proliferation.

Inhibitory Effect of Tomato Juice on Rat Urinary Bladder Carcinogenesis after N‐Butyl‐N‐(4‐hydroxybutyl)nitrosamine Initiation

E. Okajima, Y. Konishi, M. Tsutsumi, 1998, Japanese Journal of Cancer Research : Gann.

Effects of cell proliferation and cell death (apoptosis and necrosis) on the early stages of rat hepatocarcinogenesis.

A. Columbano, Y. Konishi, D. Nakae, 1996, Carcinogenesis.

Prevention by Methionine of Enhancement of Hepatocarcinogenesis by Coadministration of a Choline‐deficient L‐Amino Acid‐defined Diet and Ethionine in Rats

Y. Konishi, D. Nakae, M. Tsutsumi, 1995, Japanese journal of cancer research : Gann.

Different Roles of 8‐Hydroxyguanine Formation and 2‐Thiobarbituric Acid‐reacting Substance Generation in the Early Phase of Liver Carcinogenesis Induced by a Choline‐deficient, l‐Amino Acid‐defined Diet in Rats

H. Yoshiji, Y. Konishi, D. Nakae, 1994, Japanese journal of cancer research : Gann.

ADP Ribosyl Transferase in Rats + Possible Model of Liver Carcinogenesis Using Inhibitors of NAD

Y. Konishi, D. Nakae, M. Tsutsumi, 2011 .

Possible Model of Liver Carcinogenesis Using Inhibitors of NAD+ ADP Ribosyl Transferase in Rats

Y. Konishi, D. Nakae, M. Tsutsumi, 1986, Toxicologic pathology.

Expression of Receptor for Advanced Glycation End Products during Rat Tongue Carcinogenesis by 4-Nitroquinoline 1-Oxide and Effect of a Selective Cyclooxygenase-2 Inhibitor, Etodolac

T. Sasahira, H. Kuniyasu, T. Kirita, 2007, Pathobiology.

Inhibitory effect of dietary iron deficiency on the induction of putative preneoplastic foci in rat liver initiated with diethylnitrosamine and promoted by phenobarbital.

H. Yoshiji, Y. Konishi, D. Nakae, 1991, British Journal of Cancer.

Additive Effect of Low-Dose Diethylnitrosamine on the Initiation of Liver Carcinogenesis in Rats

Y. Konishi, D. Nakae, M. Tsutsumi, 1988 .

Enhancement of DEN initiation of liver carcinogenesis by inhibitors of NAD+ ADP ribosyl transferase in rats.

T. Ohnishi, Y. Konishi, D. Nakae, 1984, Carcinogenesis.

Differential effects of 4-hydroxyaminoquinoline-1-oxide on pancreatic and liver DNA synthesis in rats.

Y. Konishi, A. Denda, S. Inui, 1977, Chemico-biological interactions.

Inhibition by acetylsalicylic acid, a cyclo-oxygenase inhibitor, and p-bromophenacylbromide, a phospholipase A2 inhibitor, of both cirrhosis and enzyme-altered nodules caused by a choline-deficient, L-amino acid-defined diet in rats.

Y. Konishi, D. Nakae, Q. Tang, 1996, Carcinogenesis.

Rapid production of pancreatic carcinoma by initiation with N-nitroso-bis(2-oxopropyl)amine and repeated augmentation pressure in hamsters.

K. Mizumoto, Y. Konishi, M. Tsutsumi, 1988, Journal of the National Cancer Institute.

Inhibitory effect of tomato juice on rat urinary bladder carcinogenesis after N-butyl-N-(4-hydroxybutyl)nitrosamine initiation.

E. Okajima, Y. Konishi, M. Tsutsumi, 1998, Japanese journal of cancer research : Gann.

Effects of Isoliquirithigenin on the Development of Preneoplastic Liver Lesions Caused by a Choline-Deficient, L-Amino Acid-Defined Diet and on the Urinary Bladder Carcinogenesis by N-Butyl-N-(4-hydroxybutyl)nitrosamine in Rats

M. Baba, R. Puatanachokchai, H. Kuniyasu, 2003 .

Effect of vitamin E on the induction and evolution of enzyme-altered foci in the liver of rats treated with diethylnitrosamine.

Y. Konishi, M. Tsutsumi, A. Denda, 1987, Carcinogenesis.

Possible involvement of poly ADP-ribosylation in phenobarbital promotion of rat hepatocarcinogenesis.

Y. Konishi, D. Nakae, M. Tsutsumi, 1990, Carcinogenesis.

Inhibitory effects of lemon grass (Cymbopogon citratus, Stapf) extract on the early phase of hepatocarcinogenesis after initiation with diethylnitrosamine in male Fischer 344 rats.

Usanee Vinitketkumnuen, Dai Nakae, R. Puatanachokchai, 2002, Cancer letters.

Enzyme histochemical studies on transplantable pancreatic adenocarcinomas in Syrian golden hamsters.

Y. Konishi, T. Obara, M. Namiki, 1984, Experimental pathology.

Genetic resistance to chemical carcinogen-induced preneoplastic hepatic lesions in DRH strain rats.

K. Higashi, S. Higashi, K. Matsuo, 2000, Cancer research.

Sequential histopathological analysis of hepatocarcinogenesis in rats during promotion with orotic acid.

E. Laconi, S. Rajalakshmi, D. Sarma, 1994, Cancer letters.

Lack of modifying effects of 6-mercaptopurine in a medium term bioassay system for liver carcinogenesis using male F344 rats.

Y. Konishi, M. Tsutsumi, T. Tsujiuchi, 1992, Cancer letters.

5-azacytidine potentiates initiation induced by carcinogens in rat liver.

S. Rajalakshmi, D. Sarma, A. Denda, 1985, Carcinogenesis.

Resistance of DRH strain rats to chemical carcinogenesis of liver: genetic analysis of later progression stage.

K. Higashi, S. Higashi, Y. Konishi, 2002, Carcinogenesis.

Induction of 8-hydroxydeoxyguanosine but not initiation of carcinogenesis by redox enzyme modulations with or without menadione in rat liver.

D. Nakae, M. Tsutsumi, Q. Tang, 1991, Carcinogenesis.

Enhancing effect of partial pancreatectomy and ethionine-induced pancreatic regeneration on the tumorigenesis of azaserine in rats.

Y. Konishi, S. Takahashi, A. Denda, 1978, Gan.

Pancreatic carcinoma induced by 4-hydroxyaminoquinoline 1-oxide after partial pancreatectomy and splenectomy in rats.

Y. Konishi, S. Takahashi, A. Denda, 1976, Gan.

Histochemical studies on gamma-glutamyltranspeptidase activity of pancreatic acinar cell lesions induced by 4-hydroxyaminoquinoline 1-oxide and/or azaserine in rats.

Y. Konishi, T. Obara, A. Denda, 1987, Experimental pathology.

Inhibition by piroxicam of oxidative DNA damage, liver cirrhosis and development of enzyme-altered nodules caused by a choline-deficient, L-amino acid-defined diet in rats.

E. Okajima, Y. Konishi, D. Nakae, 1997, Carcinogenesis.

Inhibition of the development of hepatocellular carcinomas by phenyl N-tert-butyl nitrone in rats fed with a choline-deficient, L-amino acid-defined diet.

Y. Kotake, Y. Konishi, D. Nakae, 2004, Cancer letters.

Studies on liver tumor promotion in the rat by orotic acid: dose and minimum exposure time required for dietary orotic acid to promote hepatocarcinogenesis.

E. Laconi, S. Rajalakshmi, D. Sarma, 1993, Carcinogenesis.

Infrequent Ki-ras and an absence of p53 mutations in hepatocellular carcinomas induced by a choline deficient L-amino acid defined diet in rats.

E. Okajima, Y. Konishi, D. Nakae, 1996, Cancer letters.

Lung carcinomas induced by oral administration of N-bis(2-hydroxypropyl)nitrosamine in rats.

Y. Konishi, S. Takahashi, A. Denda, 1976, Gan.

Temporal correlation of pathology and DNA damage with gene expression in a choline‐deficient model of rat liver injury

I. Rusyn, E. Lobenhofer, J. Parker, 2005, Hepatology.

Carcinogenic activity of endogenously synthesized N-nitrosobis(2-hydroxypropyl)amine in rats administered bis(2-hydroxypropyl)amine and sodium nitrite.

Y. Konishi, M. Tsutsumi, K. Yamamoto, 1989, Carcinogenesis.

Effect of various carcinogenic and non-carcinogenic substances on development of bladder tumors in rats induced by N-butyl-N-(4-hydroxybutyl)nitrosoamine.

N. Ito, A. Denda, K. Matsumura, 1974, Gan.

Enhanced preneoplastic liver lesion development under 'selection pressure' conditions after administration of deoxycholic or lithocholic acid in the initiation phase in rats.

Y. Konishi, M. Tsutsumi, T. Tsujiuchi, 1990, Carcinogenesis.

Lung carcinogenesis by N-nitrosobis(2-hydroxypropyl)amine-related compounds and their formation in rats.

H. Yamazaki, K. Yamamoto, A. Denda, 1987, IARC scientific publications.

Initiation activity of endogenously synthesized N-nitrosobis(2-hydroxypropyl)amine in the rat liver.

Y. Konishi, M. Tsutsumi, K. Yamamoto, 1989, Cancer Letters.

Mutagenic activation of carcinogenic N-nitrosopropylamines by liver S9 fractions from mice, rats and hamsters: evidence for a cytochrome P-450-dependent reaction.

H. Yamazaki, A. Denda, Y. Mori, 1986, Carcinogenesis.

Cycles of repeated augmentation pressure in rapid production of pancreatic and cholangiocellular carcinomas in hamsters initiated with N-nitrosobis(2-oxopropyl)amine.

K. Mizumoto, Y. Konishi, M. Tsutsumi, 1989, Carcinogenesis.

[Carcinogenic effect of the 3-di-(hydroxymethyl-)amino-6-(5-nitro-2-furylethenyl-)1,2,4-triazines in Panfuran-S on mice].

Y. Konishi, S. Takahashi, A. Denda, 1979, Onkologie.

Production of adenocarcinomas of the small intestines of Wistar rats fed panfuran-S containing 3-di(hydroxymethyl)amino-6-(5-nitro-2-furylethenyl)-1,2,4-triazine.

Y. Konishi, S. Takahashi, A. Denda, 1978, Journal of the National Cancer Institute.

Usefulness of rapid production model for pancreatic carcinoma in male hamsters.

K. Mizumoto, Y. Konishi, M. Tsutsumi, 1990, Cancer letters.

Effects of 3-aminobenzamide on the induction of gamma-glutamyl-transpeptidase-positive foci by various chemicals in rat liver.

Y. Konishi, M. Tsutsumi, A. Denda, 1988, Cancer letters.

Chronic toxicity and carcinogenicity studies of 2-methylnaphthalene in B6C3F1 mice.

Y. Konishi, D. Nakae, M. Tsutsumi, 1993, Fundamental and applied toxicology : official journal of the Society of Toxicology.

Inhibition by catechol and di(2-ethylhexyl)phthalate of pancreatic carcinogenesis after initiation with N-nitrosobis(2-hydroxypropyl)amine in Syrian hamsters.

Y. Konishi, M. Tsutsumi, T. Tsujiuchi, 1994, Carcinogenesis.

Delayed DNA Synthesis Induced by 3‐Aminobenzamide in Partially Hepatectomized Liver of Rats

M. Miwa, Y. Konishi, M. Tsutsumi, 1992, Japanese journal of cancer research : Gann.

Induction of rat liver gamma-glutamyltranspeptidase-positive foci by oral administration of 1-nitropyrene.

Y. Konishi, M. Tsutsumi, T. Tsujiuchi, 1989, Cancer letters.

Inhibitory effects of N,N'-diphenyl-p-phenylenediamine on the early stage of the enhanced hepatocarcinogenesis caused by coadministration of ethionine and a choline-deficient L-amino acid-defined diet in rats.

Y. Konishi, D. Nakae, M. Tsutsumi, 1996, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

Comparative Changes in the Liver of Female Fischer-344 Rats after Short-Term Feeding of a Semipurified or a Semisynthetic L-Amino Acid-Defined Choline-Deficient Diet

Y. Konishi, D. Nakae, T. Tsujiuchi, 1995, Toxicologic pathology.

Possible involvement of arachidonic acid metabolism in phenobarbital promotion of hepatocarcinogenesis.

Y. Konishi, M. Tsutsumi, T. Tsujiuchi, 1989, Carcinogenesis.

Induction of gamma-glutamyltranspeptidase-positive foci in rat liver by deoxycholic acid.

K. Mizumoto, Y. Konishi, K. Yamamoto, 1987, Japanese journal of cancer research : Gann.

Ultrastructural analysis of pulmonary alveolar proteinosis induced by methylnaphthalene in mice.

A. Denda, Y. Konishi, Y. Murata, 1992, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

Effects of catechol and its analogs on pancreatic carcinogenesis initiated by N-nitrosobis(2-oxopropyl)amine in Syrian hamsters.

S. Kondo, Y. Konishi, D. Nakae, 1991, Carcinogenesis.

Effects of 3‐Aminobenzamide on Induction of Multiorgan Carcinogenesis by N‐Nitrosobis(2‐hydroxypropyl)amine in Hamsters

Y. Konishi, M. Tsutsumi, T. Tsujiuchi, 1991, Japanese journal of cancer research : Gann.

Effects of novobiocin on the induction of gamma-glutamyltranspeptidase positive foci in the liver of rats treated with diethylnitrosamine.

Y. Konishi, M. Tsutsumi, K. Honoki, 1994, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

Effects of 3-aminobenzamide on the post-initiation phase of N-nitrosobis(2-oxopropyl)amine induced pancreatic carcinogenesis in Syrian hamsters.

K. Mizumoto, Y. Konishi, M. Tsutsumi, 1991, Cancer letters.

Effect of 3-Aminobenzamide on the Induction of γ-Glutamyltranspeptidase Positive Foci in the Liver of Rats Treated with Various Chemical Carcinogens

Y. Konishi, D. Nakae, M. Tsutsumi, 1989 .

Possible involvement of poly(ADP-ribosyl)ation in phenobarbital promotion activity in rat hepatocarcinogenesis

Y. Konishi, M. Tsutsumi, T. Tsujiuchi, 1992 .

DIPHENYL INDUCES UROLITHIASIS BUT DOES NOT POSSESS THE ABILITY TO PROMOTE CARCINOGENESIS BY N-ETHYL-N-HYDROXYETHYLNITROSAMINE IN KIDNEYS OF RATS

Y. Konishi, M. Tsutsumi, A. Denda, 1989 .

Dietary and Metabolic Manipulations of the Carcinogenic Process: Role of Nucleotide Pool Imbalances in Carcinogenesis

E. Laconi, S. Rajalakshmi, D. Sarma, 1987, Toxicologic pathology.

Diabetes-associated angiotensin activation enhances liver metastasis of colon cancer

Yi Luo, T. Sasahira, H. Kuniyasu, 2012, Clinical & Experimental Metastasis.