Sonia Donzelli

发表

Peroxynitrite and myocardial contractility: in vivo versus in vitro effects.

D. Kass, D. Wink, N. Paolocci, 2006, Free radical biology & medicine.

Dual Mechanisms of HNO Generation by a Nitroxyl Prodrug of the Diazeniumdiolate (NONOate) Class

D. Wink, J. Saavedra, L. Keefer, 2010, Journal of the American Chemical Society.

Asbestos redirects nitric oxide signaling through rapid catalytic conversion to nitrite.

D. Wink, L. Ridnour, D. Pociask, 2006, Cancer research.

Simultaneous high performance liquid chromatographic separation of purines, pyrimidines, N-acetylated amino acids, and dicarboxylic acids for the chemical diagnosis of inborn errors of metabolism.

F. Bellia, P. Leone, J. Francis, 2005, Clinical biochemistry.

A NAC domain mutation (E83Q) unlocks the pathogenicity of human alpha-synuclein and recapitulates its pathological diversity

H. Lashuel, F. Sobott, Rani Moons, 2022, Science advances.

Playing with cardiac "redox switches": the "HNO way" to modulate cardiac function.

D. Kass, D. Wink, J. V. Van Eyk, 2011, Antioxidants & redox signaling.

Nitroxyl in the central nervous system.

C. Gerloff, T. Magnus, J. Lewerenz, 2011, Antioxidants & redox signaling.

The activation of metabolites of nitric oxide synthase by metals is both redox and oxygen dependent: a new feature of nitrogen oxide signaling.

D. Wink, C. Switzer, L. Ridnour, 2006, Antioxidants & redox signaling.

Discriminating formation of HNO from other reactive nitrogen oxide species.

D. Wink, L. Ridnour, N. Paolocci, 2006, Free radical biology & medicine.

Generation of nitroxyl by heme protein-mediated peroxidation of hydroxylamine but not N-hydroxy-L-arginine.

G. C. Yeh, D. Wink, C. Switzer, 2008, Free radical biology & medicine.

Single-sample preparation for simultaneous cellular redox and energy state determination.

B. Giardina, G. Lazzarino, E. di Stasio, 2003, Analytical biochemistry.

S‐glutathiolation impairs phosphoregulation and function of cardiac myosin‐binding protein C in human heart failure

D. Dobrev, S. Sadayappan, I. Wittig, 2016, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The specificity of nitroxyl chemistry is unique among nitrogen oxides in biological systems.

D. Wink, C. Switzer, L. Ridnour, 2011, Antioxidants & redox signaling.

Nitroxyl exacerbates ischemic cerebral injury and oxidative neurotoxicity

C. Gerloff, F. Hummel, E. Schwedhelm, 2009, Journal of neurochemistry.

Pharmacological Characterization of 1-Nitrosocyclohexyl Acetate, a Long-Acting Nitroxyl Donor That Shows Vasorelaxant and Antiaggregatory Effects

C. Gerloff, S. Baldus, J. Heeren, 2013, The Journal of Pharmacology and Experimental Therapeutics.

The biphasic nature of nitric oxide responses in tumor biology.

D. Wink, L. Ridnour, D. Roberts, 2006, Antioxidants & redox signaling.

Oxidant sensor in the cGMP-binding pocket of PKGIα regulates nitroxyl-mediated kinase activity

R. Feil, Jenna Scotcher, H. Subramanian, 2017, Scientific Reports.

Revisiting the specificity and ability of phospho-S129 antibodies to capture alpha-synuclein biochemical and pathological diversity

N. Guex, H. Lashuel, C. Iseli, 2022, npj Parkinson's Disease.

Enzymatic generation of the NO/HNO-releasing IPA/NO anion at controlled rates in physiological media using β-galactosidase.

J. Saavedra, L. Keefer, Sonia Donzelli, 2013, Nitric oxide : biology and chemistry.

Comparison of the chemical biology of NO and HNO: An inorganic perspective

M. Ferlito, D. Citrin, D. Wink, 2005 .

The chemical biology of nitric oxide: implications in cellular signaling.

C. Harris, S. Ambs, C. Colton, 2008, Free radical biology & medicine.

A simple, versatile and robust centrifugation‐based filtration protocol for the isolation and quantification of α‐synuclein monomers, oligomers and fibrils: Towards improving experimental reproducibility in α‐synuclein research

H. Lashuel, A. Chiki, Senthil T. Kumar, 2019, bioRxiv.

Oxidant sensor in the cGMP-binding pocket of PKGIα regulates nitroxyl-mediated kinase activity

R. Feil, Jenna Scotcher, H. Subramanian, 2017, Scientific Reports.

Superoxide Fluxes Limit Nitric Oxide-induced Signaling*

James B. Mitchell, C. Harris, S. Ambs, 2006, Journal of Biological Chemistry.

Impact of AT2 Receptor Deficiency on Postnatal Cardiovascular Development

S. Ergün, W. Zimmermann, H. Ehmke, 2012, PloS one.

H. Lashuel, A. Chiki, Senthil T. Kumar, 2020, Journal of neurochemistry.

Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications

Jordi Villà-Freixa, Peter Sandner, Bernd J. Pichler, 2017, BMC Pharmacology and Toxicology.

Hypothesis of the Postconcussive Vulnerable Brain: Experimental Evidence of Its Metabolic Occurrence

R. Delfini, G. Lazzarino, Sonia Donzelli, 2005, Neurosurgery.

Receptor-independent modulation of cAMP-dependent protein kinase and protein phosphatase signaling in cardiac myocytes by oxidizing agents

E. Ehler, S. Sadayappan, V. Nikolaev, 2020, The Journal of Biological Chemistry.

The emergence of nitroxyl (HNO) as a pharmacological agent.

D. Wink, C. Switzer, L. Ridnour, 2009, Biochimica et biophysica acta.

Neighbouring modifications interfere with the detection of phosphorylated alpha-synuclein at Serine 129: Revisiting the specificity of pS129 antibodies

N. Guex, H. Lashuel, C. Iseli, 2022, bioRxiv.

Post-fibrillization nitration of alpha-synuclein abolishes its seeding activity and pathology formation in primary neurons and in vivo

D. D. Di Monte, H. Lashuel, A. Chiki, 2023, bioRxiv.

A novel mutation (E83Q) unlocks the pathogenicity of human alpha-synuclein fibrils and recapitulates its pathological diversity

H. Lashuel, F. Sobott, Rani Moons, 2021, bioRxiv.

Comparing the chemical biology of NO and HNO

D. Wink, C. Switzer, L. Ridnour, 2009, Archives of pharmacal research.

The new HNO donor, 1-nitrosocyclohexyl acetate, increases contractile force in normal and β-adrenergically desensitized ventricular myocytes.

C. Gerloff, L. Carrier, R. Böger, 2010, Biochemical and biophysical research communications.