K. Golovine

发表

The effect of 5-aminolevulinic acid and its derivatives on protoporphyrin IX accumulation and apoptotic cell death in castrate-resistant prostate cancer cells.

R. Uzzo, C. Myers, A. Kutikov, 2012, Urology.

Basic and Translational Science The Effect of 5-Aminolevulinic Acid and Its Derivatives on Protoporphyrin IX Accumulation and Apoptotic Cell Death in Castrate-resistant Prostate Cancer Cells

R. Uzzo, C. Myers, A. Kutikov, 2012 .

Cadmium down-regulates expression of XIAP at the post-transcriptional level in prostate cancer cells through an NF-κB-independent, proteasome-mediated mechanism

R. Uzzo, A. Kutikov, David J Kaplan, 2010, Molecular Cancer.

Zinc chelation induces rapid depletion of the X-linked inhibitor of apoptosis and sensitizes prostate cancer cells to TRAIL-mediated apoptosis

R. Uzzo, J. Rothman, P. Crispen, 2008, Cell Death and Differentiation.

LDL cholesterol counteracts the antitumour effect of tyrosine kinase inhibitors against renal cell carcinoma

R. Uzzo, I. Astsaturov, A. Kutikov, 2017, British Journal of Cancer.

Piperlongumine and its analogs down-regulate expression of c-Met in renal cell carcinoma

R. Uzzo, R. Mehrazin, A. Kutikov, 2015, Cancer biology & therapy.

Drugging DNA repair to target T-ALL cells

C. Mullighan, K. Matlawska-Wasowska, T. Skorski, 2018, Leukemia & lymphoma.

Methylseleninic acid sensitizes prostate cancer cells to TRAIL-mediated apoptosis

R. Uzzo, Kenya Yamaguchi, P. Crispen, 2005, Oncogene.

TET2 and DNMT3A Mutations Exert Divergent Effects on DNA Repair and Sensitivity of Leukemia Cells to PARP Inhibitors

M. Minden, G. Vassiliou, K. Matlawska-Wasowska, 2020, Cancer Research.

Reversal of epigenetic silencing of AP-2alpha results in increased zinc uptake in DU-145 and LNCaP prostate cancer cells.

R. Uzzo, V. Matveev, A. Kutikov, 2011, Carcinogenesis.

Uptak e in DU-145 and LNCaP Prostate Cancer Cells.

R. Uzzo, V. Matveev, A. Kutikov, 2011 .

Piperlongumine induces rapid depletion of the androgen receptor in human prostate cancer cells

R. Uzzo, A. Kutikov, E. Teper, 2013, The Prostate.

Modulation of Akt/mTOR Signaling Overcomes Sunitinib Resistance in Renal and Prostate Cancer Cells

R. Uzzo, A. Kutikov, E. Teper, 2012, Molecular Cancer Therapeutics.

Transcriptional regulation of the major zinc uptake protein hZip1 in prostate cancer cells.

R. Uzzo, P. Makhov, K. Golovine, 2009, Gene.

Co‐administration of piperine and docetaxel results in improved anti‐tumor efficacy via inhibition of CYP3A4 activity

R. Uzzo, A. Kutikov, P. Makhov, 2012, The Prostate.

Diverse effects of zinc on NF-kappaB and AP-1 transcription factors: implications for prostate cancer progression.

E. Horwitz, R. Uzzo, P. Crispen, 2006, Carcinogenesis.

Piperlongumine inhibits NF‐κB activity and attenuates aggressive growth characteristics of prostate cancer cells

Alexander Kutikov, R. Uzzo, A. Kutikov, 2014, The Prostate.

Piperlongumine promotes autophagy via inhibition of Akt/mTOR signalling and mediates cancer cell death

R. Uzzo, R. Mehrazin, A. Kutikov, 2014, British Journal of Cancer.

Non-NAD-Like poly(ADP-Ribose) Polymerase-1 Inhibitors effectively Eliminate Cancer in vivo

A. Tulin, Colin Thomas, E. Kotova, 2016, EBioMedicine.

Depletion of intracellular zinc increases expression of tumorigenic cytokines VEGF, IL‐6 and IL‐8 in prostate cancer cells via NF‐κB‐dependent pathway

Robert G Uzzo, R. Uzzo, P. Crispen, 2008, The Prostate.

Overexpression of the Zinc Uptake Transporter hZIP1 Inhibits Nuclear Factor-κB and Reduces the Malignant Potential of Prostate Cancer Cells In vitro and In vivo

R. Uzzo, D. Kunkle, P. Makhov, 2008, Clinical Cancer Research.

Three Different Promoters Control Expression of the Aromatase Cytochrome P450 Gene (Cyp19) in Mouse Gonads and Brain1

M. Schwerin, J. Vanselow, K. Golovine, 2003, Biology of reproduction.

Docetaxel‐mediated apoptosis in myeloid progenitor TF‐1 cells is mitigated by zinc: Potential implication for prostate cancer therapy

R. Uzzo, A. Kutikov, P. Makhov, 2011, The Prostate.

Vitamin E succinate inhibits NF‐κB and prevents the development of a metastatic phenotype in prostate cancer cells: Implications for chemoprevention

E. Horwitz, R. Uzzo, A. Pollack, 2007, The Prostate.

Minor grove binding ligands disrupt PARP-1 activation pathways

K. Kirsanov, E. Lesovaya, M. Yakubovskaya, 2014, Oncotarget.

TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment.

R. Levine, D. Link, I. Tempera, 2020, Cell reports.

ABL1 kinase as a tumor suppressor in AML1-ETO and NUP98-PMX1 leukemias

T. Skorski, M. Nieborowska-Skorska, J. Madzo, 2023, Blood Cancer Journal.

Interleukin-6: a potential biomarker of resistance to multitargeted receptor tyrosine kinase inhibitors in castration-resistant prostate cancer.

R. Uzzo, A. Kutikov, P. Makhov, 2011, Urology.

TET2 and DNMT3A Mutations Exert Divergent Effects on DNA Repair and Sensitivity of Leukemia Cells to PARP Inhibitors

M. Minden, G. Vassiliou, K. Matlawska-Wasowska, 2021, Cancer Research.

Co‐administration of piperine and docetaxel results in improved anti‐tumor efficacy via inhibition of CYP3A4 activity

R. Uzzo, A. Kutikov, P. Makhov, 2012, The Prostate.

Piperlongumine inhibits NF‐κB activity and attenuates aggressive growth characteristics of prostate cancer cells

R. Uzzo, A. Kutikov, K. Golovine, 2014, The Prostate.

DNA polymerase theta protects leukemia cells from metabolic-induced DNA damage.

G. Gupta, J. Jelinek, K. Matlawska-Wasowska, 2022, Blood.