Hsin-Hui Shu

Discovery of a novel trans-1,4-dioxycyclohexane GPR119 agonist series.

S. H. Kim, Michael E. Morgan, Robert M. Jones, 2015, Bioorganic & medicinal chemistry letters.

Discovery and optimization of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists.

S. H. Kim, Michael E. Morgan, K. Whelan, 2014, Bioorganic & medicinal chemistry letters.

Discovery of 2-(((1r,4r)-4-(((4-Chlorophenyl)(phenyl)carbamoyl)oxy)methyl)cyclohexyl)methoxy)acetate (Ralinepag): An Orally Active Prostacyclin Receptor Agonist for the Treatment of Pulmonary Arterial Hypertension.

John W. Adams, A. Blackburn, I. Gaidarov, 2017, Journal of medicinal chemistry.

Discovery of a new series of potent prostacyclin receptor agonists with in vivo activity in rat.

John W. Adams, Michael E. Morgan, Yunqing Shi, 2015, Bioorganic & medicinal chemistry letters.

Design of a new series of potent and selective beta-3 adrenergic receptor (β3-AdrR) antagonists for the treatment of acute decompensated heart failure

John W. Adams, C. Sage, Michael E. Morgan, 2022, Results in Chemistry.