P. Cornelius

发表

From partial to full agonism: identification of a novel 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole as a full agonist of the human GPR119 receptor.

Michael D. Hamilton, S. Wright, A. Kalgutkar, 2013, Bioorganic & medicinal chemistry letters.

Activation of the G-protein-coupled receptor 119: a conformation-based hypothesis for understanding agonist response.

A. Kalgutkar, M. Munchhof, B. Lefker, 2011, Journal of medicinal chemistry.

Effects of L-triiodothyronine and the thyromimetic L-94901 on serum lipoprotein levels and hepatic low-density lipoprotein receptor, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and apo A-I gene expression.

G. Ness, H. J. Harwood, C. Chambers, 1998, Biochemical pharmacology.

Oxidative metabolism of a quinoxaline derivative by xanthine oxidase in rodent plasma.

G. S. Walker, A. Stepan, A. Kalgutkar, 2011, Chemical research in toxicology.

The growth factor-like effects of tumor necrosis factor-alpha. Stimulation of glucose transport activity and induction of glucose transporter and immediate early gene expression in 3T3-L1 preadipocytes.

P. Pekala, P. Cornelius, M. Marlowe, 1990, The Journal of biological chemistry.

Design, Synthesis, and Pharmacology of Fluorescently Labeled Analogs of Serotonin: Application to Screening of the 5-HT2C Receptor

J. Boyd, Janice A. Brown, Wen-Kuang Lin, 2009, Journal of biomolecular screening.

Purification and properties of calmodulin from adrenal cortex.

W. A. Toscano, N. Venditti, P. Cornelius, 1985, Archives of biochemistry and biophysics.

Sequence, tissue distribution, and differential expression of mRNA for a putative insulin-responsive glucose transporter in mouse 3T3-L1 adipocytes.

K. Kaestner, M. Lane, P. Pekala, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Monokine regulation of glucose transporter mRNA in L6 myotubes.

P. Pekala, P. Cornelius, M. Marlowe, 1989, Biochemical and biophysical research communications.

Regulation of lipoprotein lipase mRNA content in 3T3-L1 cells by tumour necrosis factor.

S. Enerbäck, P. Pekala, T. Olivecrona, 1988, The Biochemical journal.

Characterization of the tumour necrosis factor receptor in human placenta.

P. Pekala, P. Cornelius, D. Eades, 1988, Placenta.

Regulation of glucose transport as well as glucose transporter and immediate early gene expression in 3T3‐L1 preadipocytes by 8‐bromo‐cAMP

K. Call, P. Pekala, K. Call, 1991, Journal of cellular physiology.

Plasma eicosanoid levels in rats with nonketotic diabetes mellitus: effect of severity.

J. Kieffer, L. Axelrod, P. Cornelius, 1986, Metabolism: clinical and experimental.

The Regulation and Activation of Ciliary Neurotrophic Factor Signaling Proteins in Adipocytes*

J. Stephens, S. Zvonic, W. C. Stewart, 2003, The Journal of Biological Chemistry.

Glucocorticoids reciprocally regulate expression of the CCAAT/enhancer-binding protein alpha and delta genes in 3T3-L1 adipocytes and white adipose tissue.

O. MacDougald, M. Lane, F. Lin, 1994, The Journal of biological chemistry.

Regulation of Glucose Transport by Tumor Necrosis Factor-α in Cultured Murine 3t3-l1 Fibroblasts

P. Pekala, P. Cornelius, M. Marlowe, 1990 .

Glucocorticoids Reciprocally Regulate Expression of the CCAATEnhancer-binding Protein a and 6 Genes in 3T3-Ll Adipocytes and White Adipose Tissue*

P. Cornelius, M., S. Chenn, 2001 .

Caldesmon inhibits skeletal actomyosin subfragment-1 ATPase activity and the binding of myosin subfragment-1 to actin.

J. Chalovich, C. Benson, P. Cornelius, 1987, The Journal of biological chemistry.

Regulation of adipocyte development.

O. MacDougald, M. Lane, P. Cornelius, 1994, Annual review of nutrition.

Design and synthesis of diazatricyclodecane agonists of the G-protein-coupled receptor 119.

Bryan M. Li, David A. Price, A. Kalgutkar, 2013, Journal of medicinal chemistry.

Discovery and evaluation of spirocyclic derivatives as antagonists of the neuropeptide Y5 receptor.

Peter Cornelius, Eunsun Lee, D. Scott, 2012, Bioorganic & medicinal chemistry letters.

Extensive bone marrow necrosis in patients with cancer and tumor necrosis factor activity in plasma

P. Pekala, C. Knupp, P. Cornelius, 1988, American journal of hematology.

Insulin Regulates Transcription of the CCAAT/Enhancer Binding Protein (C/EBP) , , and Genes in Fully-differentiated 3T3-L1 Adipocytes (*)

O. MacDougald, M. Lane, P. Cornelius, 1995, The Journal of Biological Chemistry.

Plasma prostaglandin levels and circulating fuel levels in rats with diabetic ketoacidosis: effects of cyclooxygenase inhibitors and of alpha and beta adrenergic blockade.

L. Axelrod, P. Cornelius, 1984, Prostaglandins.

Cell-free transcription directed by the 422 adipose P2 gene promoter: activation by the CCAAT/enhancer binding protein.

M. Lane, D. Geiman, R. Christy, 1991, Proceedings of the National Academy of Sciences of the United States of America.

The first 22 base pairs of the proximal promoter of the rat class I alcohol dehydrogenase gene is bipartite and interacts with multiple DNA-binding proteins.

V. Yang, D. Crabb, E. Mezey, 1992, Archives of biochemistry and biophysics.

Identification of potent, selective, CNS-targeted inverse agonists of the ghrelin receptor.

L. Michael, T. Goosen, M. Tu, 2013, Bioorganic & medicinal chemistry letters.

Design and evaluation of a 2-(2,3,6-trifluorophenyl)acetamide derivative as an agonist of the GPR119 receptor.

A. Kalgutkar, K. Farley, M. Munchhof, 2011, Bioorganic & Medicinal Chemistry Letters.

Orally active and brain permeable proline amides as highly selective 5HT2c agonists for the treatment of obesity.

K. Liu, B. Lefker, Janice A. Brown, 2010, Bioorganic & medicinal chemistry letters.

Design and synthesis of orally-active and selective azaindane 5HT2c agonist for the treatment of obesity.

T. Maurer, K. Liu, Janice A. Brown, 2010, Bioorganic & medicinal chemistry letters.

Intrinsic electrophilicity of a 4-substituted-5-cyano-6-(2-methylpyridin-3-yloxy)pyrimidine derivative: structural characterization of glutathione conjugates in vitro.

A. Kalgutkar, M. Munchhof, R. Robinson, 2011, Chemical research in toxicology.

Discovery of a novel series of 6-azauracil-based thyroid hormone receptor ligands: potent, TR beta subtype-selective thyromimetics.

Peter Cornelius, Eunsun Lee, Dennis E Danley, 2003, Bioorganic & medicinal chemistry letters.