T. Imaeda

发表

Design, synthesis, and biological evaluation of a series of piperazine ureas as fatty acid amide hydrolase inhibitors.

Y. Shimizu, H. Matsui, Takahiro Matsumoto, 2014, Bioorganic & medicinal chemistry.

BTZO-1, a cardioprotective agent, reveals that macrophage migration inhibitory factor regulates ARE-mediated gene expression.

H. Oki, M. Takizawa, S. Tanida, 2010, Chemistry & biology.

Melanin-concentrating hormone receptor 1 antagonists. Synthesis and structure-activity relationships of novel 3-(aminomethyl)quinolines.

Koki Kato, Y. Nakano, Toshio Tanaka, 2012, Journal of medicinal chemistry.

Identification of a selective DDX3X inhibitor with newly developed quantitative high-throughput RNA helicase assays.

Masahiro Ito, S. Aparicio, T. Kawamoto, 2020, Biochemical and biophysical research communications.

Novel Pure αVβ3 Integrin Antagonists That Do Not Induce Receptor Extension, Prime the Receptor, or Enhance Angiogenesis at Low Concentrations

M. Foley, T. Walz, J. Takagi, 2019, bioRxiv.

BTZO-15, an ARE-Activator, Ameliorates DSS- and TNBS-Induced Colitis in Rats

M. Takizawa, Yoshimi Sato, T. Imaeda, 2011, PloS one.

Design, Synthesis, and Optimization of Macrocyclic Peptides as Species-Selective Antimalaria Proteasome Inhibitors.

J. Vendôme, M. Michino, C. Nathan, 2022, Journal of medicinal chemistry.

A new class of potent nonpeptide luteinizing hormone-releasing hormone (LHRH) antagonists: design and synthesis of 2-phenylimidazo[1,2-a]pyrimidin-5-ones.

Masataka Harada, Masahiko Fujino, Shuichi Furuya, 2002, Bioorganic & medicinal chemistry letters.

A New Class of Potent Nonpeptide Luteinizing Hormone-Releasing Hormone (LHRH) Antagonists: Design and Synthesis of 2-Phenylimidazo[1,2-a]pyrimidin-5-one.

S. Sasaki, M. Fujino, M. Harada, 2002 .

Design, synthesis, and structure-activity relationships of thieno[2,3-b]pyridin-4-one derivatives as a novel class of potent, orally active, non-peptide luteinizing hormone-releasing hormone receptor antagonists.

S. Sasaki, T. Imada, H. Matsumoto, 2006, Journal of medicinal chemistry.

Discovery of a novel, potent, and orally active nonpeptide antagonist of the human luteinizing hormone-releasing hormone (LHRH) receptor.

S. Sasaki, T. Imada, H. Matsumoto, 1998, Journal of medicinal chemistry.

Enantiospecific synthesis of optically active natural (+)-conhydrine from (S,S)-tartaric acid

T. Imaeda, Y. Masaki, H. Oda, 1990 .

Discovery, synthesis, and structure-activity relations of 3,4-dihydro-1H-spiro(naphthalene-2,2'-piperidin)-1-ones as potassium-competitive acid blockers.

Terufumi Takagi, T. Imaeda, F. Itoh, 2017, Bioorganic & medicinal chemistry.

Identification of a novel fluoropyrrole derivative as a potassium-competitive acid blocker with long duration of action.

Teruki Hamada, T. Imaeda, F. Itoh, 2017, Bioorganic & medicinal chemistry.

Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance

M. Foley, P. Rosenthal, P. Bhanot, 2018, Proceedings of the National Academy of Sciences.

Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice

M. Ascano, T. Tuschl, D. Patel, 2017, Nature Communications.

Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression

T. Tuschl, D. Patel, A. Stamford, 2019, Nature Communications.

Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression

T. Tuschl, D. Patel, A. Stamford, 2019, Nature Communications.

Discovery, synthesis, and structure-activity relationship of 6-aminomethyl-7,8-dihydronaphthalenes as human melanin-concentrating hormone receptor 1 antagonists.

Koki Kato, Y. Nakano, S. Endo, 2011, Bioorganic & Medicinal Chemistry.

Structure-Activity Relationship Studies of Antimalarial Plasmodium Proteasome Inhibitors─Part II.

M. Foley, J. Vendôme, N. Liverton, 2023, Journal of medicinal chemistry.

Selective Phenylimidazole-based Inhibitors of the Mycobacterium tuberculosis Proteasome.

M. Foley, Huilin Li, M. Michino, 2019, Journal of medicinal chemistry.

Publisher Correction: Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice

M. Ascano, T. Tuschl, D. Patel, 2017, Nature Communications.

Development of a highly selective Plasmodium falciparum proteasome inhibitor with anti-malaria activity in humanized mice.

P. Rosenthal, J. Vendôme, M. Michino, 2021, Angewandte Chemie.

Macrocyclic Peptides that Selectively Inhibit the Mycobacterium tuberculosis Proteasome.

M. Foley, Huilin Li, J. Vendôme, 2021, Journal of medicinal chemistry.

Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice

M. Ascano, T. Tuschl, D. Patel, 2017, Nature Communications.

Design and synthesis of 6-methylpyridin-2-one derivatives as novel and potent GluN2A positive allosteric modulators for the treatment of cognitive impairment.

Tomoaki Hasui, M. Corsi, H. Kakei, 2022, Bioorganic & medicinal chemistry.