Lijiao Zhao

发表

Water Carcinogenicity and Prevalence of HPV Infection in Esophageal Cancer Patients in Huaihe River Basin, China

Yi Zeng, Lei Zhang, Maliha Ghaffar, 2018, Gastroenterology research and practice.

Synthesis and antitumor activity evaluation of a novel combi-nitrosourea prodrug: Designed to release a DNA cross-linking agent and an inhibitor of O(6)-alkylguanine-DNA alkyltransferase.

N. Zhang, R. Zhong, Lijiao Zhao, 2016, Bioorganic & medicinal chemistry.

In vivo toxicity of nitroaromatic compounds to rats: QSTR modelling and interspecies toxicity relationship with mouse.

Yongzhen Peng, Xiaoyu Tang, N. Zhang, 2020, Journal of hazardous materials.

Reductive Activity and Mechanism of Hypoxia- Targeted AGT Inhibitors: An Experimental and Theoretical Investigation

N. Zhang, Junjun Liu, R. Zhong, 2019, International journal of molecular sciences.

DFT study on the stereoisomeric effect of amino-acid side chain on the formation of penta-coordinate phosphorus carboxylic-phosphoric mixed anhydride

R. Zhong, Lijiao Zhao, Yan Zhen, 2007 .

Ab initio Studies on the Carcinogenic Mechanism of the Derivatives of 3,5-Dimethyl-Nitrosopiperazine

Ting-ting Liu, Lijiao Zhao, Ru-gang Zhong, 2008, 2008 2nd International Conference on Bioinformatics and Biomedical Engineering.

Chemopreventive Role of Apigenin against the Synergistic Carcinogenesis of Human Papillomavirus and 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone

Yuancong Xu, Yuhe Chen, P. Chan, 2020, Biomedicines.

Machine Learning Models for the Classification of CK2 Natural Products Inhibitors with Molecular Fingerprint Descriptors

R. Zhong, Lijiao Zhao, Guohui Sun, 2021, Processes.

DFT investigations of phosphotriesters hydrolysis in aqueous solution: a model for DNA single strand scission induced by N-nitrosoureas

Tingting Liu, R. Zhong, Lijiao Zhao, 2013, Journal of Molecular Modeling.

In Silico Prediction of O6-Methylguanine-DNA Methyltransferase Inhibitory Potency of Base Analogs with QSAR and Machine Learning Methods

Yongzhen Peng, Xiaodong Sun, R. Zhong, 2018, Molecules.

One step synthesis of antimicrobial peptide protected silver nanoparticles: The core-shell mutual enhancement of antibacterial activity.

Feng Zhang, Ruibo Zhong, Liping Wang, 2019, Colloids and surfaces. B, Biointerfaces.

Study on N-Nitrosoureas by Electron Spray Ionization Mass Spectrometry

Lijiao Zhao, Shu-fen Zhang, Ru-gang Zhong, 2008, 2008 2nd International Conference on Bioinformatics and Biomedical Engineering.

Influence of the Expression Level of O6-Alkylguanine-DNA Alkyltransferase on the Formation of DNA Interstrand Crosslinks Induced by Chloroethylnitrosoureas in Cells: A Quantitation Using High-Performance Liquid Chromatography-Mass Spectrometry

R. Zhong, Lijiao Zhao, Guohui Sun, 2015, PloS one.

The potential of combi-molecules with DNA-damaging function as anticancer agents.

R. Zhong, Lijiao Zhao, Guohui Sun, 2017, Future medicinal chemistry.

1′H-Indole-3′-Carbonyl-Thiazole-4-Carboxylic Acid Methyl Ester Blocked Human Glioma Cell Invasion via Aryl Hydrocarbon Receptor's Regulation of Cytoskeletal Contraction

Lijiao Zhao, Hui-Juan Sun, Pei Gong, 2020, BioMed research international.

Targeting Aryl Hydrocarbon Receptor with small molecule, 1′H-indole-3′-carbonyl-thiazole-4-carboxylic acid methyl ester blocked human glioma cell invasion via MYH9

Lijiao Zhao, Hui-Juan Sun, Pei Gong, 2020, bioRxiv.

Quantification of meCCNU-induced dG-dC crosslinks in oligonucleotide duplexes by liquid chromatography/electrospray ionization tandem mass spectrometry.

R. Zhong, Lijiao Zhao, Bao-Qing Bai, 2011, Rapid communications in mass spectrometry : RCM.

Structural Characterization of the DNA Adducts Induced by 1,3-Bis-(2-Chloroethyl)-1-Nitrosourea Using Electrospray Ionization Tandem Mass Spectrometry

Lijiao Zhao, Ru-gang Zhong, Bao-Qing Bai, 2010, 2010 4th International Conference on Bioinformatics and Biomedical Engineering.

Environmental toxicity risk evaluation of nitroaromatic compounds: Machine learning driven binary/multiple classification and design of safe alternatives.

Feifan Li, R. Zhong, Lijiao Zhao, 2022, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

The specific role of O6-methylguanine-DNA methyltransferase inhibitors in cancer chemotherapy.

Yongzhen Peng, R. Zhong, Lijiao Zhao, 2018, Future medicinal chemistry.

[Determination of trace lead in environmental water by cloud point extraction-high resolution continuum source graphite furnace atomic absorption spectrometry].

Lijiao Zhao, Ru-gang Zhong, Ting Ren, 2012, Guang pu xue yu guang pu fen xi = Guang pu.

DFT studies on the quantitative structure-activity relationship of N-(2-chloroethyl)-N′-cyclohexyl-N-nitrosoureas as anticancer agents

R. Zhong, Lijiao Zhao, W. Liu, 2010, 2010 3rd International Conference on Biomedical Engineering and Informatics.

A density functional theory investigation on the formation mechanisms of DNA interstrand crosslinks induced by chloroethylnitrosoureas

R. Zhong, Lijiao Zhao, Xin‐Yan Ma, 2013 .

Quantification of DNA interstrand crosslinks induced by ACNU in NIH/3T3 and L1210 cells using high-performance liquid chromatography/electrospray ionization tandem mass spectrometry.

R. Zhong, Lijiao Zhao, Lili Li, 2014, Rapid communications in mass spectrometry : RCM.

Quantitation of pyridyloxobutyl-DNA adducts in tissues of rats treated chronically with (R)- or (S)-N'-nitrosonornicotine (NNN) in a carcinogenicity study.

S. Hecht, P. Villalta, S. Balbo, 2013, Chemical research in toxicology.

Mass Spectrometric Quantitation of Pyridyloxobutyl DNA Phosphate Adducts in Rats Chronically Treated with N'-Nitrosonornicotine.

S. Hecht, S. Balbo, Yupeng Li, 2019, Chemical research in toxicology.

The mechanism of DNA alkylation by the β-electrophilic center of nitrosamines and nitrosoureas: a theoretical study

Lijiao Zhao, Yan Zhen, Ru-gang Zhong, 2007, 2007 IEEE/ICME International Conference on Complex Medical Engineering.

Determination of Pb (Lead), Cd (Cadmium), Cr (Chromium), Cu (Copper), and Ni (Nickel) in Chinese tea with high-resolution continuum source graphite furnace atomic absorption spectrometry

Wen-Si Zhong, Ting Ren, Li-Jiao Zhao, 2015, Journal of food and drug analysis.

Determination of lead, cadmium, copper, and nickel in the tonghui river of beijing, china, by cloud point extraction-high resolution continuum source graphite furnace atomic absorption spectrometry.

Lijiao Zhao, Ru-gang Zhong, Ting Ren, 2013, Journal of environmental quality.

Determination of Lead in Human Hair by High Resolution Continuum Source Graphite Furnace Atomic Absorption Spectrometry with Microwave Digestion and Solid Sampling

R. Zhong, Lijiao Zhao, Ting Ren, 2012 .

Structure-based identification of novel CK2 inhibitors with a linear 2-propenone scaffold as anti-cancer agents.

M. Jacobson, N. Zhang, Liming Hu, 2019, Biochemical and biophysical research communications.

Comparative theoretical investigation of the formation of DNA interstrand crosslinks induced by two kinds of N-nitroso compounds: nitrosoureas and nitrosamines

R. Zhong, Lijiao Zhao, Xin‐Yan Ma, 2012 .

A Theoretical Study on the Critical Difference between the Mechanism of DNA Alkylation by Nitrosamines and Nitrosoureas

Yan Zhen, Rugang Zhong, Lijiao Zhao, 2008, 2008 International Conference on BioMedical Engineering and Informatics.

Theoretical researches on the molecular structures of DNA crosslinks induced by chloroethylnitrosoureas and QSAR analysis

R. Zhong, Lijiao Zhao, Yan Zhen, 2007 .

Quantitative Structure-Activity Relationship Analysis of the Anticancer Activity of Chloroethylnitrosourea Derivatives

Lijiao Zhao, Yan Zhen, Ru-gang Zhong, 2007, 2007 1st International Conference on Bioinformatics and Biomedical Engineering.

Structure‐based Discovery of Novel CK2α‐Binding Cyclic Peptides with Anti‐cancer Activity

M. Jacobson, N. Zhang, Lijiao Zhao, 2018, Molecular informatics.

Tumor Energy Metabolism and Potential of 3-Bromopyruvate as an Inhibitor of Aerobic Glycolysis: Implications in Tumor Treatment

Yongzhen Peng, Xiaodong Sun, R. Zhong, 2019, Cancers.

Comparative investigation of the DNA inter-strand crosslinks induced by ACNU, BCNU, CCNU and FTMS using high-performance liquid chromatography–electrospray ionization tandem mass spectrometry

R. Zhong, Lijiao Zhao, Lili Li, 2014 .

Synthesis and Antitumor Activity Evaluation of a Novel Combi-nitrosourea Prodrug: BGCNU.

N. Zhang, Xinxin Lai, R. Zhong, 2017, ACS medicinal chemistry letters.

Measurement of O(6)-alkylguanine-DNA alkyltransferase activity in tumour cells using stable isotope dilution HPLC-ESI-MS/MS.

R. Zhong, Lijiao Zhao, Guohui Sun, 2016, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Identification of the Structural Features of Guanine Derivatives as MGMT Inhibitors Using 3D-QSAR Modeling Combined with Molecular Docking

N. Zhang, R. Zhong, Lijiao Zhao, 2016, Molecules.

3-Bromopyruvate Regulates the Status of Glycolysis and BCNU Sensitivity in Human Hepatocellular Carcinoma Cells.

Yongzhen Peng, Xiaoyu Tang, N. Zhang, 2020, Biochemical pharmacology.

Agarose Gel Electrophoresis and Fluorometric Assays for the Determination of DNA Cross-Linking Induced by Semustine

Wei Tang, Lijiao Zhao, Ru-gang Zhong, 2008, 2008 2nd International Conference on Bioinformatics and Biomedical Engineering.

The dual role of DNA repair protein MGMT in cancer prevention and treatment.

R. Zhong, Lijiao Zhao, Guohui Sun, 2023, DNA repair.

NBGNU: a hypoxia-activated tripartite combi-nitrosourea prodrug overcoming AGT-mediated chemoresistance.

N. Zhang, Xinxin Lai, R. Zhong, 2019, Future medicinal chemistry.

HPLC-ESI-MS/MS Research on DNA Interstrand Cross-Links Formed by 1,3-Bis-(2-Chloroethyl)-1-Nitrosourea

Lijiao Zhao, Ru-gang Zhong, Bao-Qing Bai, 2009, 2009 3rd International Conference on Bioinformatics and Biomedical Engineering.

A COMPARISON OF THE STEREOISOMERIC PENTA-COORDINATED PHOSPHORUS INTERMEDIATES FORMED FROM 19 DIMETHOXYL N-PHOSPHORYL AMINO ACIDS BY DFT CALCULATIONS

Tingting Liu, R. Zhong, Lijiao Zhao, 2011 .

Metabolic Activation and Carcinogenesis of Tobacco-Specific Nitrosamine N’-Nitrosonornicotine (NNN): A Density Function Theory and Molecular Docking Study

R. Zhong, Lijiao Zhao, Guohui Sun, 2019, International journal of environmental research and public health.

Insights into the Impact of Linker Flexibility and Fragment Ionization on the Design of CK2 Allosteric Inhibitors: Comparative Molecular Dynamics Simulation Studies

N. Zhang, Yongzhen Peng, R. Zhong, 2018, International journal of molecular sciences.

Exploring the Pivotal Role of the CK2 Hinge Region Sub-Pocket in Binding with Tricyclic Quinolone Analogues by Computational Analysis

Yongzhen Peng, N. Zhang, R. Zhong, 2017, Molecules.

The Potential of Lonidamine in Combination with Chemotherapy and Physical Therapy in Cancer Treatment

Yongzhen Peng, Feifan Li, Xiaodong Sun, 2020, Cancers.

2-Deoxy-D-glucose increases the sensitivity of glioblastoma cells to BCNU through the regulation of glycolysis, ROS and ERS pathways: in vitro and in vivo validation.

Xiaodong Sun, Yongzhen Peng, R. Zhong, 2022, Biochemical pharmacology.

Development and biological evaluation of AzoBGNU: A novel hypoxia-activated DNA crosslinking prodrug with AGT-inhibitory activity.

R. Zhong, Lijiao Zhao, Guohui Sun, 2021, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

AN ONIOM STUDY ON THE CROSSLINKED BASE PAIRS IN DNA REACTED WITH CHLOROETHYLNITROSOUREAS

R. Zhong, Lijiao Zhao, Yan Zhen, 2007 .

Determination of heavy metals in cigarettes using high-resolution continuum source graphite furnace atomic absorption spectrometry

R. Zhong, Lijiao Zhao, Chen Xi, 2017 .

QSAR and Classification Study on Prediction of Acute Oral Toxicity of N-Nitroso Compounds

Guohui Sun, Tengjiao Fan, Lijiao Zhao, 2018, International journal of molecular sciences.

Identification of Pharmacophoric Fragments of DYRK1A Inhibitors Using Machine Learning Classification Models

R. Zhong, Jianhua Wang, Lijiao Zhao, 2022, Molecules.

Synergistic Effect between Human Papillomavirus 18 and 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone on Malignant Transformation of Immortalized SHEE Cells.

P. Chan, Na Zhang, R. Zhong, 2019, Chemical research in toxicology.

Ab initio Researches on the Mechanism of DNA Alkylation by Nitrosamines

Tingting Liu, R. Zhong, Lijiao Zhao, 2007, 2007 IEEE/ICME International Conference on Complex Medical Engineering.

Development of the C12Im-Cl-assisted method for rapid sample preparation in proteomic application.

W. Ying, X. Qian, Chang Liu, 2021, Analytical methods : advancing methods and applications.

Quantitative Structure-Activity Relationship (QSAR) Studies on the Toxic Effects of Nitroaromatic Compounds (NACs): A Systematic Review

Yongzhen Peng, R. Zhong, Lijiao Zhao, 2021, International journal of molecular sciences.

Prediction on the mutagenicity of nitroaromatic compounds using quantum chemistry descriptors based QSAR and machine learning derived classification methods.

Yuxing Hao, Guohui Sun, Tengjiao Fan, 2019, Ecotoxicology and environmental safety.

Glycolytic Inhibition by 3-Bromopyruvate Increases the Cytotoxic Effects of Chloroethylnitrosoureas to Human Glioma Cells and the DNA Interstrand Cross-Links Formation.

Yongzhen Peng, Xiaoyu Tang, N. Zhang, 2020, Toxicology.

Underlying mechanisms of cyclic peptide inhibitors interrupting the interaction of CK2α/CK2β: comparative molecular dynamics simulation studies.

Lijiao Zhao, Rugang Zhong, Na Zhang, 2016, Physical chemistry chemical physics : PCCP.

Ecotoxicological QSAR modelling of the acute toxicity of fused and non-fused polycyclic aromatic hydrocarbons (FNFPAHs) against two aquatic organisms: Consensus modelling and comparison with ECOSAR.

Yongzhen Peng, R. Zhong, Lijiao Zhao, 2023, Aquatic toxicology.

Ecotoxicological QSAR study of fused/non-fused polycyclic aromatic hydrocarbons (FNFPAHs): Assessment and priority ranking of the acute toxicity to Pimephales promelas by QSAR and consensus modeling methods.

Yuancong Xu, R. Zhong, Lijiao Zhao, 2023, The Science of the total environment.

Modulating MGMT expression through interfering with cell signaling pathways.

R. Zhong, Lijiao Zhao, Guohui Sun, 2023, Biochemical pharmacology.

Hypoxia and CD44 receptors dual-targeted nano-micelles with AGT-inhibitory activity for the targeting delivery of carmustine.

R. Zhong, Lijiao Zhao, Guohui Sun, 2023, International journal of biological macromolecules.

Quantitative Analysis of DNA Interstrand Crosslink Induced by Chloroethylnitrosoureas with Real-Time Fluorometric Assay

Wei Tang, Lijiao Zhao, Ru-gang Zhong, 2010, 2010 4th International Conference on Bioinformatics and Biomedical Engineering.

Relationship between the molecular structure and the anticancer activity of N‐(2‐chloroethyl)‐N′‐cyclohexyl‐N‐nitrosoureas: A theoretical investigation

R. Zhong, Lijiao Zhao, Jun Cao, 2012 .

Identification and Biological Evaluation of CK2 Allosteric Fragments through Structure-Based Virtual Screening

N. Zhang, R. Zhong, Lijiao Zhao, 2020, Molecules.

QSAR and Chemical Read-Across Analysis of 370 Potential MGMT Inactivators to Identify the Structural Features Influencing Inactivation Potency

G. Margison, R. Zhong, Lijiao Zhao, 2023, Pharmaceutics.

The potential of combi-molecules with DNA-damaging function as anticancer agents.

R. Zhong, Lijiao Zhao, Guohui Sun, 2017, Future medicinal chemistry.

Chemometric QSAR modeling of acute oral toxicity of Polycyclic Aromatic Hydrocarbons (PAHs) to rat using simple 2D descriptors and interspecies toxicity modeling with mouse.

Yongzhen Peng, Feifan Li, Chen Li, 2021, Ecotoxicology and environmental safety.

Development of Prediction Models for the Mutagenicity of Nitrated-PAHs Based on Multiple Linear Regression

Lijiao Zhao, Ru-gang Zhong, Wen-jing Zhang, 2018, DEStech Transactions on Computer Science and Engineering.

[Determination of Pb, Cd and Cr in food by high resolution continuum source graphite furnace atomic absorption spectrometry].

Jun-Yan Cao, Lijiao Zhao, Ru-gang Zhong, 2012, Guang pu xue yu guang pu fen xi = Guang pu.

Prioritization of the ecotoxicological hazard of PAHs towards aquatic species spanning three trophic levels using 2D-QSTR, read-across and machine learning-driven modelling approaches.

Lijiao Zhao, Guohui Sun, Tengjiao Fan, 2024, Journal of hazardous materials.

First report on the QSAR modelling and multistep virtual screening of the inhibitors of nonstructural protein Nsp14 of SARS-CoV-2: reducing unnecessary chemical synthesis and experimental tests

Lijiao Zhao, Guohui Sun, Tengjiao Fan, 2024, Arabian Journal of Chemistry.

Mechanism of AGT-Mediated Repair of dG-dC Cross-Links in the Drug Resistance to Chloroethylnitrosoureas: Molecular Docking, MD Simulation, and ONIOM (QM/MM) Investigation

Lijiao Zhao, Guohui Sun, Ting Ren, 2024, J. Chem. Inf. Model..

Energy Blocker Lonidamine Reverses Nimustine Resistance in Human Glioblastoma Cells through Energy Blockade, Redox Homeostasis Disruption, and O6-Methylguanine-DNA Methyltransferase Downregulation: In Vitro and In Vivo Validation

Lijiao Zhao, Guohui Sun, Tengjiao Fan, 2024, ACS Pharmacology & Translational Science.

Recent advances in chemometric modelling of inhibitors against SARS-CoV-2

Lijiao Zhao, Guohui Sun, Rugang Zhong, 2024, Heliyon.

Identification of potential natural product derivatives as CK2 inhibitors based on GA-MLR QSAR modeling, synthesis and biological evaluation

Lijiao Zhao, Guohui Sun, Tengjiao Fan, 2024, Medicinal Chemistry Research.

A multi-functional hypoxia/esterase dual stimulus responsive and hyaluronic acid-based nanomicelle for targeting delivery of chloroethylnitrosouea

R. Zhong, Lijiao Zhao, Guohui Sun, 2023, Journal of Nanobiotechnology.

A Tween-80 modified hypoxia/esterase dual stimulus-activated nanomicelle as a delivery platform for carmustine - Design, synthesis, and biological evaluation

Lijiao Zhao, Guohui Sun, Ting Ren, 2024, International Journal of Biological Macromolecules.