J. Hildebrandt

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Small bite, large impact–saliva and salivary molecules in the medicinal leech, Hirudo medicinalis

J. Hildebrandt, Sarah Lemke, 2011, Naturwissenschaften.

Sphingomyelin Depletion from Plasma Membranes of Human Airway Epithelial Cells Completely Abrogates the Deleterious Actions of S. aureus Alpha-Toxin

A. Beule, Christian Müller, J. Hildebrandt, 2019, Toxins.

Major Determinants of Airway Epithelial Cell Sensitivity to S. aureus Alpha-Toxin: Disposal of Toxin Heptamers by Extracellular Vesicle Formation and Lysosomal Degradation

U. Völker, C. Hentschker, J. Hildebrandt, 2021, Toxins.

Hirudins of the Asian medicinal leech, Hirudinaria manillensis: same same, but different

B. Rauch, Christian Müller, J. Hildebrandt, 2019, Parasitology Research.

Hirudin and Decorsins of the North American Medicinal Leech Macrobdella decora: Gene Structure Reveals Homology to Hirudins and Hirudin-Like Factors of Eurasian Medicinal Leeches

Christian Müller, J. Hildebrandt, Sarah Lemke, 2019, Journal of Parasitology.

Lysophosphatidic acid depletes intracellular calcium stores different from those mediating capacitative calcium entry in C6 rat glioma cells

P. Hildebrandt, J. Hildebrandt, P. Hildebrandt, 1997, Glia.

A Multi-Omics Approach Identifies Key Hubs Associated with Cell Type-Specific Responses of Airway Epithelial Cells to Staphylococcal Alpha-Toxin

J. Mostertz, Falko Hochgräfe, R. K. Chilukoti, 2015, PloS one.

Attenuation of cell cycle regulator p27Kip1 expression in vertebrate epithelial cells mediated by extracellular signals in vivo and in vitro

A. Prowald, Christian Müller, P. Hildebrandt, 2005, Journal of Comparative Physiology B.

Expression levels and activities of energy-yielding ATPases in the oligohaline neritid snail Theodoxus fluviatilis under changing environmental salinities

Christian Müller, J. Hildebrandt, Jan Knobloch, 2022, Biology open.

Impact of Salinity on the Gastrointestinal Bacterial Community of Theodoxus fluviatilis

J. Knobloch, D. Herlemann, V. Kisand, 2020, Frontiers in Microbiology.

Molecular cloning and sequencing of the Na+/K+‐ATPase α‐subunit of the medical leech Hirudo medicinalis (Annelida) – implications for modelling protostomian evolution

C. Mueller, K. Kusche, J. Hildebrandt, 2005 .

A second look at leptin and adiponectin actions on the growth of primary porcine myoblasts under serum-free conditions

M. Palin, J. Kuzinski, C. Rehfeldt, 2014 .

Differences in osmotolerance in freshwater and brackish water populations of Theodoxus fluviatilis (Gastropoda: Neritidae) are associated with differential protein expression

J. Hildebrandt, Frauke Symanowski, 2010, Journal of Comparative Physiology B.

The effects of bradykinin on K+ currents in NG108–15 cells treated with U73122, a phospholipase C inhibitor, or neomycin

H. Meves, T. Plant, J. Hildebrandt, 1997, British journal of pharmacology.

Ca(2+) and p38 MAP kinase regulate mAChR-mediated c-Fos expression in avian exocrine cells.

A. Prowald, J. Hildebrandt, 2000, American journal of physiology. Cell physiology.

Estrogen-like effects of ultraviolet screen 3-(4-methylbenzylidene)-camphor (Eusolex 6300) on cell proliferation and gene induction in mammalian and amphibian cells.

I. Lutz, W. Kloas, Christian Müller, 2005, Environmental research.

Differences in the expression of soluble proteins in freshwater and brackish‐water ecotypes of the snail Theodoxus fluviatilis

D. Albrecht, Christian Müller, J. Hildebrandt, 2022, Invertebrate Biology.

Immunsysteme

J. Hildebrandt, H. Bleckmann, Uwe Homberg, 2021, Penzlin - Lehrbuch der Tierphysiologie.

The cyanotoxin cylindrospermopsin slows down cell cycle progression and extends metaphase duration in immortalised human airway epithelial cells.

J. Hildebrandt, Sabine Ziesemer, Janita Vennmann, 2022, Toxicon : official journal of the International Society on Toxinology.

Make it double: identification and characterization of a Tandem-Hirudin from the Asian medicinal leech Hirudinaria manillensis

Christian Müller, J. Hildebrandt, Phil Lukas, 2022, Parasitology Research.

S. aureus haemolysin A‐induced IL‐8 and IL‐6 release from human airway epithelial cells is mediated by activation of p38‐ and Erk‐MAP kinases and additional, cell type‐specific signalling mechanisms

U. Völker, A. Konkel, Christian Müller, 2013, Cellular microbiology.

Virulence factors of Staphylococcus aureus induce Erk-MAP kinase activation and c-Fos expression in S9 and 16HBE14o- human airway epithelial cells.

S. Engelmann, C. Kohler, A. Konkel, 2009, American journal of physiology. Lung cellular and molecular physiology.

Downregulation of aquaporins 1 and 5 in nasal gland by osmotic stress in ducklings, Anas platyrhynchos: implications for the production of hypertonic fluid

M. Sendler, Christian Müller, J. Hildebrandt, 2006, Journal of Experimental Biology.

Vertebrate salt glands: short- and long-term regulation of function.

T. Shuttleworth, J. Hildebrandt, Jan-Peter Hildebrandt, 1999, The Journal of experimental zoology.

In vivo and in vitro induction of c- fos in avian exocrine salt gland cells.

J. Hildebrandt, R. Gerstberger, M. Schwarz, 1998, American journal of physiology. Cell physiology.

CALL FOR PAPERS Ion Channels and Transporters in Lung Function and Disease Staphylococcus aureus (cid:2) -toxin-mediated cation entry depolarizes membrane potential and activates p38 MAP kinase in airway epithelial cells

Christian Müller, J. Hildebrandt, J. Behnke, 2016 .

Staphylococcus aureus hemolysin A disrupts cell-matrix adhesions in human airway epithelial cells.

A. Beule, R. Dress, Christian Müller, 2015, American journal of respiratory cell and molecular biology.

Adaptive differentiation of avian exocrine cells alters their pHi response to mAChR activation.

J. Hildebrandt, C. Bentz, 1995, The American journal of physiology.

Life without blood: Molecular and functional analysis of hirudins and hirudin‐like factors of the Asian non‐hematophagous leech Whitmania pigra

Zhongjie Wang, Christian Müller, J. Hildebrandt, 2022, Journal of thrombosis and haemostasis : JTH.

Short tail stories: the hirudin-like factors HLF6 and HLF7 of the Asian medicinal leech, Hirudinaria manillensis

Christian Müller, J. Hildebrandt, Dana Sponholz, 2021, Parasitology Research.

The hirudin-like factors HLF3 and HLF4—hidden hirudins of European medicinal leeches

Christian Müller, J. Hildebrandt, Phil Lukas, 2020, Parasitology Research.

Hirudin or hirudin‐like factor ‐ that is the question: insights from the analyses of natural and synthetic HLF variants

Christian Müller, J. Hildebrandt, Phil Lukas, 2019, FEBS letters.

Target Mechanisms of the Cyanotoxin Cylindrospermopsin in Immortalized Human Airway Epithelial Cells

B. Kubickova, Susann Meyer, J. Hildebrandt, 2022, Toxins.

Inositol phosphates and [Ca2+]i signals in a differentiating exocrine cell.

T. Shuttleworth, J. Hildebrandt, 1991, The American journal of physiology.

ATP Release from Human Airway Epithelial Cells Exposed to Staphylococcus aureus Alpha-Toxin

Christian Müller, J. Hildebrandt, Sabine Ziesemer, 2016, Toxins.

Hirudins of the Asian medicinal leech, Hirudinaria manillensis: same same, but different

B. Rauch, Christian Müller, J. Hildebrandt, 2019, Parasitology Research.

Streptococcus pneumoniae Infection of Host Epithelial Cells via Polymeric Immunoglobulin Receptor Transiently Induces Calcium Release from Intracellular Stores*

S. Hammerschmidt, J. Hildebrandt, T. Asmat, 2011, The Journal of Biological Chemistry.

Effects of Staphylococcus aureus-hemolysin A on calcium signalling in immortalized human airway epithelial cells.

S. Engelmann, M. Hecker, U. Völker, 2009, Cell calcium.

Cross-talk of phosphoinositide- and cyclic nucleotide-dependent signaling pathways in differentiating avian nasal gland cells

M. Krohn, J. Hildebrandt, 2004, Journal of Comparative Physiology B.

Lysophosphatidic acid induces inositol phosphate and calcium signals in exocrine cells from the avian nasal salt gland

J. Hildebrandt, 1995, The Journal of Membrane Biology.

A Gq-type G protein couples muscarinic receptors to inositol phosphate and calcium signaling in exocrine cells from the avian salt gland

T. Shuttleworth, J. Hildebrandt, 1993, The Journal of Membrane Biology.

Granulomatous inflammation of salt glands in ducklings (Anas platyrhynchos) associated with intralesional Gram-negative bacteria

R. Klopfleisch, J. Teifke, Christian Müller, 2005, Avian Pathology.

Be ready at any time: postprandial synthesis of salivary proteins in salivary gland cells of the haematophagous leech Hirudo verbana

Christian Müller, J. Hildebrandt, Sarah Lemke, 2016, Journal of Experimental Biology.

More than just one: multiplicity of Hirudins and Hirudin-like Factors in the Medicinal Leech, Hirudo medicinalis

Christian Müller, J. Hildebrandt, Sarah Lemke, 2016, Molecular Genetics and Genomics.

Coping with excess salt: adaptive functions of extrarenal osmoregulatory organs in vertebrates.

J. Hildebrandt, 2001, Zoology.

Alanine, proline and urea are major organic osmolytes in the snail Theodoxus fluviatilis under hyperosmotic stress

Christian Müller, J. Hildebrandt, A. A. Wiesenthal, 2019, Journal of Experimental Biology.

Cell-free synthesis of the hirudin variant 1 of the blood-sucking leech Hirudo medicinalis

S. Kubick, Christian Müller, D. Wüstenhagen, 2020, Scientific Reports.

Hirudins and hirudin-like factors in Hirudinidae: implications for function and phylogenetic relationships

M. Haase, Christian Müller, J. Hildebrandt, 2016, Parasitology Research.

Novel mammalian cell lines expressing reporter genes for the detection of environmental chemicals activating endogenous aryl hydrocarbon receptors (ArhR) or estrogen receptors (ER).

Christian Müller, J. Hildebrandt, S. Below, 2008, Toxicology in vitro : an international journal published in association with BIBRA.

Chloride and Potassium Conductances of Mouse Pancreatic Zymogen Granules Are Inversely Regulated by a 80-kDa mdr1a Gene Product (*)

F. Thévenod, H. D. de Jonge, J. Striessnig, 1996, The Journal of Biological Chemistry.

Phenotypic Plasticity in Animals Exposed to Osmotic Stress – Is it Always Adaptive?

Christian Müller, J. Hildebrandt, A. A. Wiesenthal, 2018, BioEssays : news and reviews in molecular, cellular and developmental biology.

Effect of salt and volume loading on the circulation in the leech,Hirudo medicinalis L.

I. Zerbst-Boroffka, J. Hildebrandt, 1988, Journal of Comparative Physiology B.

External CO2 levels influence energy yielding metabolic pathways under hypoxia in the Leech, Hirudo medicinalis

J. Hildebrandt, 1992 .

Effects of cylindrospermopsin on cultured immortalized human airway epithelial cells.

P. Babica, K. Hilscherová, B. Kubickova, 2019, Chemosphere.

Pore-forming virulence factors of Staphylococcus aureus destabilize epithelial barriers-effects of alpha-toxin in the early phases of airway infection

J. Hildebrandt, 2015 .

Chloride and potassium conductances of mouse pancreatic zymogen granules are inversely regulated by a approximately 80-kDa mdr1a gene product.

F. Thévenod, H. D. de Jonge, J. Striessnig, 1996, The Journal of biological chemistry.

Adhesion of bovine and goat salivary proteins to dental enamel and silicate (short communication)

J. Langbein, C. Rehfeldt, M. Mau, 2006 .

S. aureus alpha-toxin monomer binding and heptamer formation in host cell membranes – Do they determine sensitivity of airway epithelial cells toward the toxin?

U. Völker, P. Hildebrandt, J. Hildebrandt, 2020, PloS one.

Staphylococcus aureus Alpha-Toxin Mediates General and Cell Type-Specific Changes in Metabolite Concentrations of Immortalized Human Airway Epithelial Cells

M. Lalk, J. Mostertz, Falko Hochgräfe, 2014, PloS one.

Staphylococcus aureus &agr;‐Toxin Induces Actin Filament Remodeling in Human Airway Epithelial Model Cells

A. Beule, Falko Hochgräfe, Christian Müller, 2017, American journal of respiratory cell and molecular biology.

Produktion mechanischer Energie

J. Hildebrandt, H. Bleckmann, Uwe Homberg, 2021, Penzlin - Lehrbuch der Tierphysiologie.

Zirkulation

J. Hildebrandt, H. Bleckmann, Uwe Homberg, 2021, Penzlin - Lehrbuch der Tierphysiologie.

Partial hepatectomy in rats results in immediate down-regulation of p27Kip1 in residual liver tissue by transcriptional and post-translational processes

Christian Müller, J. Hildebrandt, Anne-Katrin Rohlfing, 2013, Front. Physiol..

Wärmehaushalt: Adaptation und Regulation

J. Hildebrandt, H. Bleckmann, Uwe Homberg, 2021 .

Ecology Meets Physiology: Phenotypic Plasticity and the Ability of Animals to Adjust to Changing Environmental Conditions

J. Hildebrandt, 2023, Physiologia.

Staphylococcus aureus α-toxin-mediated cation entry depolarizes membrane potential and activates p38 MAP kinase in airway epithelial cells.

Christian Müller, J. Hildebrandt, J. Behnke, 2016, American journal of physiology. Lung cellular and molecular physiology.

Ion Channels and Transporters in Lung Function and Disease Staphylococcus aureus-toxin-mediated cation entry depolarizes membrane potential and activates p 38 MAP kinase in airway epithelial cells

Christian Müller, J. Hildebrandt, J. Behnke, 2016 .

Detection of PrP(Sc) in peripheral tissues of clinically affected cattle after oral challenge with bovine spongiform encephalopathy.

M. Groschup, J. Richt, A. Balkema-Buschmann, 2012, The Journal of general virology.

Detection of PrPSc in peripheral tissues of clinically affected cattle after oral challenge with bovine spongiform encephalopathy

M. Groschup, J. Richt, A. Balkema-Buschmann, 2012 .

The Ins and Outs of Urea: Identification of Putative DUR3-like Urea Transporters in the Oligohaline Nerite Snail Theodoxus fluviatilis and Their Expression under Changing Salinities

Montserrat Torres-Oliva, J. Fuss, Christian Müller, 2023, Physiologia.

The hirudin-like factors HLF3 and HLF4—hidden hirudins of European medicinal leeches

Christian Müller, J. Hildebrandt, Phil Lukas, 2020, Parasitology Research.

More than just one: multiplicity of Hirudins and Hirudin-like Factors in the Medicinal Leech, Hirudo medicinalis

Christian Müller, J. Hildebrandt, Sarah Lemke, 2015, Molecular Genetics and Genomics.

Circulation in the Leech, Hirudo Medicinalis L

Jan-Peter Hildebrandt, J. Hildebrandt, 1988 .