I. Pareyn

发表

ADAMTS‐13 plasma level determination uncovers antigen absence in acquired thrombotic thrombocytopenic purpura and ethnic differences

H. Deckmyn, K. Vanhoorelbeke, H. Feys, 2006, Journal of thrombosis and haemostasis : JTH.

Mutation of the H-bond acceptor S119 in the ADAMTS13 metalloprotease domain reduces secretion and substrate turnover in a patient with congenital thrombotic thrombocytopenic purpura.

M. de Maeyer, H. Deckmyn, C. Van Geet, 2009, Blood.

Long-Term Prevention of Congenital Thrombotic Thrombocytopenic Purpura in ADAMTS13 Knockout Mice by Sleeping Beauty Transposon-Mediated Gene Therapy

Z. Izsvák, H. Deckmyn, S. D. De Meyer, 2017, Arteriosclerosis, thrombosis, and vascular biology.

Rational humanization of the powerful antithrombotic anti-GPIbα antibody: 6B4

J. Desmet, H. Deckmyn, K. Vanhoorelbeke, 2006, Thrombosis and Haemostasis.

Inhibition of von Willebrand factor-platelet glycoprotein Ib interaction prevents and reverses symptoms of acute acquired thrombotic thrombocytopenic purpura in baboons.

H. Deckmyn, K. Vanhoorelbeke, J. Roodt, 2012, Blood.

Reduced ADAMTS13 levels in patients with acute and chronic cerebrovascular disease

C. Drechsler, C. Kleinschnitz, H. Deckmyn, 2017, PloS one.

Platelet-derived VWF is not essential for normal thrombosis and hemostasis but fosters ischemic stroke injury in mice.

B. Nieswandt, C. Kleinschnitz, H. Deckmyn, 2015, Blood.

Thrombotic thrombocytopenic purpura directly linked with ADAMTS13 inhibition in the baboon (Papio ursinus).

H. Deckmyn, K. Vanhoorelbeke, J. Roodt, 2010, Blood.

The Novel S527F Mutation in the Integrin β3 Chain Induces a High Affinity αIIbβ3 Receptor by Hindering Adoption of the Bent Conformation*

T. Springer, N. Kieffer, O. Pradier, 2009, Journal of Biological Chemistry.

Plasma glycocalicin as a source of GPIbα in the von Willebrand factor ristocetin cofactor ELISA

M. Hoylaerts, J. Arnout, H. Deckmyn, 2004, Thrombosis and Haemostasis.

N-acetylcysteine in preclinical mouse and baboon models of thrombotic thrombocytopenic purpura.

H. Deckmyn, José A López, C. Tersteeg, 2017, Blood.

Two Functional Active Conformations of the Integrin α2β1, Depending on Activation Condition and Cell Type*

G. R. Van de Walle, Z. Majer, H. Deckmyn, 2005, Journal of Biological Chemistry.

Restoration of Plasma von Willebrand Factor Deficiency Is Sufficient to Correct Thrombus Formation After Gene Therapy for Severe von Willebrand Disease

P. Lenting, T. VandenDriessche, M. Chuah, 2008, Arteriosclerosis, thrombosis, and vascular biology.

Antithrombin p.Thr147Ala: The First Founder Mutation in People of African Origin Responsible for Inherited Antithrombin Deficiency

J. Corral, V. Vicente, I. Martínez-Martínez, 2020, Thrombosis and Haemostasis.

Phenotypic correction of von Willebrand disease type 3 blood-derived endothelial cells with lentiviral vectors expressing von Willebrand factor.

R. Hebbel, T. VandenDriessche, M. Chuah, 2006, Blood.

Plasma glycocalicin as a source of GPIb α in the von Willebrand factor ristocetin cofactor ELISA New Technologies and Diagnostic Tools

M. Hoylaerts, J. Arnout, H. Deckmyn, 2017 .

Anti-ADAMTS13 Antibodies and a Novel Heterozygous p.R1177Q Mutation in a Case of Pregnancy-Onset Immune-Mediated Thrombotic Thrombocytopenic Purpura

J. Voorberg, H. Deckmyn, C. Tersteeg, 2018, TH open : companion journal to thrombosis and haemostasis.

Anti-ADAMTS13 Antibodies and a Novel Heterozygous p.R1177Q Mutation in a Case of Pregnancy-Onset Immune-Mediated Thrombotic Thrombocytopenic Purpura

J. Voorberg, H. Deckmyn, C. Tersteeg, 2018, TH Open.

False positive results in chimeraplasty for von Willebrand Disease.

H. Deckmyn, S. D. De Meyer, K. Vanhoorelbeke, 2007, Thrombosis research.

Differences in von Willebrand factor function in type 2A von Willebrand disease and left ventricular assist device‐induced acquired von Willebrand syndrome

H. Deckmyn, C. Tersteeg, S. D. De Meyer, 2018, Research and practice in thrombosis and haemostasis.

Open ADAMTS13, induced by antibodies, is a biomarker for subclinical immune-mediated thrombotic thrombocytopenic purpura.

B. Lämmle, H. Rossmann, J. Voorberg, 2020, Blood.

ADAMTS13 inhibition to treat acquired von Willebrand syndrome during mechanical circulatory support device implantation

S. Susen, A. Rauch, B. Meyns, 2022, Journal of thrombosis and haemostasis : JTH.

Antibodies that conformationally activate ADAMTS13 allosterically enhance metalloprotease domain function.

H. Deckmyn, S. D. De Meyer, K. Vanhoorelbeke, 2020, Blood advances.

Anti‐ADAMTS13 autoantibodies in immune‐mediated thrombotic thrombocytopenic purpura do not hamper ELISA‐based quantification of ADAMTS13 antigen

G. Kaplanski, A. Dewaele, P. Coppo, 2020, Journal of thrombosis and haemostasis : JTH.

Child‐onset thrombotic thrombocytopenic purpura caused by p.R498C and p.G259PfsX133 mutations in ADAMTS13

Bogac Ercig, G. Nicolaes, H. Deckmyn, 2018, European journal of haematology.

congenital thrombotic thrombocytopenic purpura domain reduces secretion and substrate turnover in a patient with Mutation of the H-bond acceptor S119 in the ADAMTS13 metalloprotease

H. Deckmyn, K. Vanhoorelbeke, H. Feys, 2009 .

Shielding of the A1 Domain by the D′D3 Domains of von Willebrand Factor Modulates Its Interaction with Platelet Glycoprotein Ib-IX-V*

P. Lenting, H. Deckmyn, H. Ulrichts, 2006, Journal of Biological Chemistry.

von Willebrand factor increases in experimental cerebral malaria but is not essential for late‐stage pathogenesis in mice

P. E. Van den Steen, L. Desender, H. Deckmyn, 2020, Journal of thrombosis and haemostasis : JTH.

Type 2B von Willebrand disease in seven individuals from three different families: Phenotypic and genotypic characterization

H. Deckmyn, K. Vanhoorelbeke, I. Salles, 2007, Thrombosis and Haemostasis.

Shielding of the A 1 Domain by the D D 3 Domains of von Willebrand Factor Modulates Its Interaction with Platelet Glycoprotein

P. Lenting, H. Deckmyn, H. Ulrichts, 2006 .

High and long‐term von Willebrand factor expression after Sleeping Beauty transposon‐mediated gene therapy in a mouse model of severe von Willebrand disease

Z. Izsvák, H. B. Samal, Z. Ivics, 2018, Journal of thrombosis and haemostasis : JTH.

The distal carboxyterminal domains of murine ADAMTS13 influence proteolysis of platelet‐decorated VWF strings in vivo

H. Deckmyn, S. D. De Meyer, K Vanhoorelbeke, 2010, Journal of thrombosis and haemostasis : JTH.

The A/T1381 polymorphism in the A1-domain of von Willebrand factor influences the affinity of von Willebrand factor for platelet glycoprotein Ibα

H. Deckmyn, K. Freson, S. D. De Meyer, 2007, Thrombosis and Haemostasis.

Anti-ADAMTS13 Autoantibodies against Cryptic Epitopes in Immune-Mediated Thrombotic Thrombocytopenic Purpura

J. Voorberg, G. Vidarsson, L. Desender, 2018, Thrombosis and Haemostasis.

MRI assessment of blood outgrowth endothelial cell homing using cationic magnetoliposomes.

T. Dresselaers, U. Himmelreich, K. Braeckmans, 2011, Biomaterials.

Rational humanization of the powerful antithrombotic anti-GPIbalpha antibody: 6B4.

J. Desmet, H. Deckmyn, K. Vanhoorelbeke, 2006, Thrombosis and haemostasis.

Humanization by variable domain resurfacing and grafting on a human IgG4, using a new approach for determination of non-human like surface accessible framework residues based on homology modelling of variable domains.

Karen Vanhoorelbeke, J. Desmet, H. Deckmyn, 2006, Molecular immunology.

Generation of anti-idiotypic antibodies to detect anti-spacer antibody idiotopes in acute thrombotic thrombocytopenic purpura patients

J. Voorberg, P. Coppo, H. Deckmyn, 2018, Haematologica.

Generation of Anti-Murine ADAMTS13 Antibodies and Their Application in a Mouse Model for Acquired Thrombotic Thrombocytopenic Purpura

H. Deckmyn, C. Tersteeg, S. D. De Meyer, 2016, PloS one.

Two functional active conformations of the integrin {alpha}2{beta}1, depending on activation condition and cell type.

G. R. Van de Walle, Z. Majer, H. Deckmyn, 2005, The Journal of biological chemistry.

While not essential for normal thrombosis and hemostasis , platelet-derived VWF fosters ischemic stroke injury in mice

Christoph, B. Nieswandt, H. Deckmyn, 2015 .

Acquired von Willebrand syndrome in patients on long-term left ventricular assist device support: Results of a Belgian center.

H. Deckmyn, C. Tersteeg, S. D. De Meyer, 2019, Thrombosis research.

MRI assessment of blood outgrowth endothelial cell homing using cationic magnetoliposomes.

T. Dresselaers, U. Himmelreich, K. Braeckmans, 2011, Biomaterials.