M. Shiozaki

发表

Toll-Like Receptor 4-MD-2 Complex Mediates the Signal Transduction Induced by Flavolipin, an Amino Acid-Containing Lipid Unique to Flavobacterium meningosepticum1

Y. Kawai, M. Nishijima, K. Kawasaki, 2002, The Journal of Immunology.

Flavolipin , an Amino Acid-Containing Lipid Mediates the Signal Transduction Induced by Toll-Like Receptor 4-MD2 Complex

Y. Kawai, M. Nishijima, K. Kawasaki, 2002 .

Conversion of D-glucose to L-glucose: oxidative decarboxylation of .alpha.-oxycarboxylic acids via their diacyl peroxides

M. Shiozaki, 1991 .

Establishment of tree seedlings and water-soluble nutrients in coarse woody debris in an old-growth Picea-Abies forest in Hokkaido, northern Japan

Masamichi Takahashi, M. Shiozaki, Y. Sakai, 2000 .

Molecular basis for lipopolysaccharide mimetic action of Taxol™ and flavolipin

Y. Kawai, M. Nishijima, K. Kawasaki, 2003, Journal of endotoxin research.

RCAI-61, the 6′-O-methylated analog of KRN7000: its synthesis and potent bioactivity for mouse lymphocytes to produce interferon-γ in vivo

T. Tashiro, K. Mori, M. Taniguchi, 2008 .

Total synthesis of sphingofungin E from d-glucose derivative

Tsuyoshi Nakamura, M. Shiozaki, 2002 .

Syntheses of hydantocidin and C-2-thioxohydantocidin.

M. Shiozaki, 2001, Carbohydrate research.

Synthesis and biological activity of hydroxylated analogues of KRN7000 (α-galactosylceramide).

T. Tashiro, K. Mori, M. Taniguchi, 2013, Carbohydrate research.

Synthesis of a tetrahydropyrano[2,3-d]oxazole analogue of trehazolin

H. Hanzawa, H. Haruyama, M. Shiozaki, 1996 .

RCAI-133, an N-methylated analogue of KRN7000, activates mouse natural killer T cells to produce Th2-biased cytokines

T. Tashiro, K. Mori, M. Taniguchi, 2013 .

Synthesis and biological activity of ester and ether analogues of alpha-galactosylceramide (KRN7000).

T. Tashiro, K. Mori, M. Taniguchi, 2010, Carbohydrate research.

SYNTHESES OF 1-DEOXYNOJIRIMYCIN-TREHALAMINE-FUSED AND -LINKED COMPOUNDS AND THEIR BIOLOGICAL ACTIVITIES

O. Ubukata, H. Haruyama, O. Ando, 1998 .

Synthesis of Substances Related to Gibberellins. XXIII

K. Mori, M. Shiozaki, M. Matsui, 1968 .

Stereospecific synthesis of chiral precursors of thienamycin from L-threonine

H. Maruyama, M. Shiozaki, T. Hiraoka, 1984 .

Stereocontrolled syntheses of chiral and racemic key intermediates to thienamycin from d-allo-threonine and trans-crotonic acid

H. Maruyama, M. Shiozaki, T. Hiraoka, 1983 .

Synthesis and Biological Activity of 3,7-Anhydro-2,4-dideoxy-4-[(R)-3-hydroxytetradecanoylamino]-6-O-phosphono-5-O-[(R)-3-(tetradecanoyloxy)tetradecanoyl]-D-glycero-D-ido-octonic Acid Derivatives.

M. Shiozaki, S. Kurakata, Takanori Wakabayashi, 2001 .

Synthesis of GLA-60 type pyran carboxylic acids with an alkyl chain instead of an ester chain as LPS-antagonists.

M. Nishijima, M. Shiozaki, Y. Watanabe, 2001, Carbohydrate research.

Synthesis of 2,6-anhydro-3-deoxy-5-O-phosphono-3-tetradecanamido-4-O-[(R)-3-(tetradecanoyloxy)tetradecanoyl]-d-glycero-d- ido-heptonic acid as a new potent endotoxin antagonist and its dimeric analogue

M. Nishijima, M. Shiozaki, T. Tatsuta, 1996 .

Synthesis of 1-deoxynojirimycin-trehalamine fused compound and its related compounds

O. Ubukata, H. Haruyama, M. Shiozaki, 1998 .

Syntheses of Trehazolin Derivatives and Evaluation as Glycosidase Inhibitors

O. Ando, Yoshiyuki Kobayashi, M. Shiozaki, 1995 .

Syntheses of Trehazolin, Trehalamine, and the Aminocyclitol Moiety of Trehazolin: Determination of Absolute Configuration of Trehazolin

Yoshiyuki Kobayashi, M. Shiozaki, H. Miyazaki, 1994 .

Synthesis of 2-Amino-2-deoxy-α-D-altrofuranoside Derivatives from 2,3-O-Isopropylidene-D-glyceraldehyde via Bicyclic β-Lactam Intermediates

Sadao. Sato, M. Shiozaki, N. Ishida, 1989 .

Preparation and reactions of optically active 6-(2,4-dimethoxybenzyl)-2-[(1', 2'-O-isopropylidene)ethyl]-4-methoxy-3-oxa-7-oxo-6-azabicyclo[3.2.0]heptane. Syntheses of 2-amino-2,3-dideoxy(branched-chain)sugar analogues

M. Shiozaki, N. Ishida, 1987 .

A Synthesis of a Versatile Intermediate Leading to Thienamycin Analogs

H. Maruyama, M. Shiozaki, T. Hiraoka, 1985 .

New short step synthesis of 3-hydroxyethyl-4-cyanoazetidin-2-one derivative: a potential precursor of the penems and the carbapenems

H. Maruyama, M. Shiozaki, N. Ishida, 1984 .

Synthesis of 3-hydroxyethyl-4-oxoazetidin-2-ylphosphonate derivatives: potential precursors to carbapenem and α-aminophosphonic acid derivatives

M. Shiozaki, H. Masuko, 1984 .

Stereocontrolled syntheses of chiral intermediates of thienamycin from threonines

M. Shiozaki, T. Hiraoka, H. Yanagisawa, 1982 .

Base-induced cyclization of N-(bis(ethoxycarbonyl)methyl)-2-bromo-3-hydroxybutyramide derivatives.

H. Maruyama, M. Shiozaki, T. Hiraoka, 1984 .

Total Synthesis of Neodysiherbaine A via 1,3-Dipolar Cycloaddition of a Chiral Nitrone Template.

T. Hirai, Yoshimitsu Hashimoto, N. Morita, 2017, Organic letters.

Synthesis of optically active azetidin-2-ones from L-threonine

M. Shiozaki, A. Ando, T. Hiraoka, 1983 .

A stereocontrolled formal total synthesis of (±)-thienamycin

M. Shiozaki, T. Hiraoka, 1982 .

Stereocontrolled syntheses of chiral intermediates of thienamycin from threonines

M. Shiozaki, T. Hiraoka, H. Yanagisawa, 1981 .

A Synthesis of Optically Active 4-Diethoxyphosphinyl-3-(1-hydroxyethyl)-2-azetidinone: A Potential Precursor to (1-Aminoalkyl)phosphonic Acid Derivatives

M. Shiozaki, H. Masuko, 1987 .

Cyclization reaction of n-propargyl epoxyamide to acetylenic 2-azetidinone, a precursor to thienamycin and related carbapenems

H. Maruyama, M. Shiozaki, T. Hiraoka, 1985 .

Syntheses and biological activities of new carbapenem derivatives.

H. Maruyama, M. Shiozaki, S. Sugawara, 1984, The Journal of antibiotics.

SYNTHESIS OF A 2-AMINOHEXAHYDROBENZOXAZOLE ANALOGUE RELATED TO TREHAZOLIN

H. Hanzawa, H. Haruyama, O. Ando, 1995 .

Photochemistry of β-hydroxy-γ-pyrone. A new synthesis of 3-methylcyclopent-2-en-2-ol-1-one from maltol

M. Shiozaki, T. Hiraoka, 1972 .

Diterpenoid total synthesis—XXI : The synthesis of 4,4-bisnorgrayanotoxin skeleton by photochemical rearrangement of cross-conjugated cyclohexadienones

K. Mori, M. Shiozaki, M. Matsui, 1974 .

Photochemical synthesis of compounds with grayanotoxin skeleton

K. Mori, M. Shiozaki, M. Matsui, 1972 .

Synthesis of substances related to gibberellins—XXI : Total synthesis of (±)-gibberellins A2, A4, A9, and A10

K. Mori, M. Shiozaki, M. Matsui, 1969 .

Synthesis of substances related to Gibberellins : Part XVIII. Total synthesis of(±)-gibberellins A(in2), A(in4), A(in9) and A(10)

K. Mori, M. Shiozaki, M. Matsui, 1968 .

Stereocontrolled Syntheses of 6-epi-Trehazolin and 6-epi-Trehalamine from D-Ribonolactone

S. Miyamoto, T. Takayama, H. Haruyama, 1994 .

Synthesis of the lactone precursor to hydroxyethylene dipeptide isostere from 3,4,6-tri-O-acetyl-D-glucal

T. Hata, M. Shiozaki, Y. Furukawa, 1989 .

Syntheses and absolute configurations of trehazolin and its aglycon

Yoshiyuki Kobayashi, M. Shiozaki, H. Miyazaki, 1992 .

Practical stereoselective synthesis of alpha-linked C-glucosamine propionic acid esters: conversion to GLA-60 derivatives.

M. Shiozaki, S. Kurakata, Takanori Wakabayashi, 2002, Carbohydrate research.

Synthesis and Biological Activity of 3,7‐Anhydro‐2,4‐dideoxy‐4‐ [(R)‐3‐hydroxytetradecanoylamino]‐6‐O‐phosphono‐5‐O‐ [(R)‐3‐(tetradecanoyloxy)tetradecanoyl]‐D‐glycero‐D‐ido‐octonic Acid Derivatives.

M. Shiozaki, S. Kurakata, Takanori Wakabayashi, 2002 .

Syntheses of 2,6-anhydro-3-deoxy-5-O-phosphono-3-tetradecanamido-4-O-[(R)-3-(tetradecanoyloxy)tetradecanoyl]-D-glycero-D-ido-heptonic acid, its dimeric analogue, and related compounds

M. Nishijima, H. Maeda, M. Shiozaki, 1997 .

Synthesis of Tetrahydropyran-2-carboxylic Acid Derivatives of Lipid A Containing an Olefin in Their Chains and Their LPS-Antagonistic Activities

M. Shiozaki, T. Shimozato, D. Tanaka, 2003 .

Synthesis of Carboxymethyl GLA-60 Ether Derivatives Containing an Olefin in Their Chains and Their LPS-Antagonistic Activities

Tsuyoshi Nakamura, M. Shiozaki, S. Kurakata, 2003 .

Synthesis of lipid A type carboxymethyl derivatives with ether chains instead of ester chains and their LPS-antagonistic activities.

M. Nishijima, M. Shiozaki, S. Kurakata, 2003, Carbohydrate research.

Syntheses of 1-O-carboxyalkyl GLA-60 analogues.

M. Shiozaki, T. Tatsuta, T. Mochizuki, 1996, Carbohydrate research.

Syntheses of 1-O-[5-(carboxy)pentanoyl]-2-deoxy-2-(2,2- difluorotetradecanamido)-3-O-[(R)-3-(tetradecanoyloxy)tetradecanoyl]-4- O- phosphono-alpha-D-glucopyranose and its analogues.

M. Nishijima, Y. Akamatsu, M. Shiozaki, 1995, Bioscience, biotechnology, and biochemistry.

Synthesis of a 3-ether analogue of lipid A.

M. Nishijima, Y. Akamatsu, M. Shiozaki, 1991, Carbohydrate research.

Synthesis of 2-deoxy-2-[(3R)-3-hydroxytetradecanamido]-3-O-[(3R)-3- hydroxytetradecanyl]-alpha-D-glucopyranosyl dihydrogen phosphate and 2-deoxy-2-[(3R)-3-hydroxytetradecanamido]-3-O-[(3R)-3- hydroxytetradecanyl]-4-O-phosphono-D-glucopyranose.

M. Nishijima, Y. Akamatsu, M. Shiozaki, 1991, Carbohydrate research.

Synthesis of 2-deoxy-2-[(2,2-difluoro-3-hydroxytetradecanoyl)amino]-3-O- [(R)-3-(tetradecanoyloxy)tetradecanoyl]-D-glucopyranose 4-phosphate.

M. Shiozaki, T. Watanabe, T. Hiraoka, 1991, Journal of medicinal chemistry.

The First Syntheses of GLA-60 Positional Isomers and Their Biological Activities.

M. Nishijima, H. Maeda, M. Shiozaki, 1997 .

Synthesis of 2,6‐Anhydro‐3‐deoxy‐5‐O‐phosphono‐3‐tetradecanamido‐4‐O‐(( R)‐3‐(tetradecanoyloxy)tetradecanoyl)‐D‐glycero‐D‐ido‐heptonic Acid as a New Potent Endotoxin Antagonist and Its Dimeric Analogue.

M. Nishijima, M. Shiozaki, T. Tatsuta, 1997 .

Synthesis of renin inhibitors possessing hydroxyethylene isostere residue from 3,4,6-tri-O-acetyl-D-qlucal via lactone precursor

T. Hata, Yoshiyuki Kobayashi, M. Shiozaki, 1991 .

Total synthesis of sphingofungin E

Tsuyoshi Nakamura, M. Shiozaki, 2001 .

Stereo-controlled synthesis of intermediates of (±)-thienamycin

M. Shiozaki, T. Hiraoka, 1980 .

Toll-Like Receptor 4-MD-2 Complex Mediates the Signal Transduction Induced by Flavolipin, an Amino Acid-Containing Lipid Unique to Flavobacterium meningosepticum

Y. Kawai, M. Nishijima, K. Kawasaki, 2002, The Journal of Immunology.

Synthesis of 5-epi-trehazolin (trehalostatin).

H. Haruyama, M. Shiozaki, Y. Kobayashi, 1994, The Journal of antibiotics.

Synthesis of trehazolin beta-anomer.

M. Shiozaki, Y. Kobayashi, 1994, The Journal of antibiotics.

Synthesis of 6-epi-trehazolin from d-ribonolactone: Evidence for the non-existence of a 5,6-ringfused structural isomer of 6-epi-trehazolin

H. Haruyama, Yoshiyuki Kobayashi, M. Shiozaki, 1994 .

Synthesis and absolute configuration of trehazolin aminocyclitol moiety

Yoshiyuki Kobayashi, M. Shiozaki, H. Miyazaki, 1993 .

Synthesis and biological activity of 4',8-dihydroxyisoflavon-7-yl D-hexopyranosides.

M. Shiozaki, Y. Watanabe, R. Kamegai, 2001, Carbohydrate research.

Synthesis of 4′,8-dihydroxyisoflavon-7-yl α-d-arabinofuranoside

M. Shiozaki, 1999 .

Synthesis of 6‐epi‐Trehazolin from D‐Ribonolactone: Evidence for the Non‐Existence of a 5,6‐Ring‐Fused Structural Isomer of 6‐epi‐ Trehazolin.

H. Haruyama, Yoshiyuki Kobayashi, M. Shiozaki, 1994 .

Synthesis and Absolute Configuration of Trehazolin Aminocyclitol Moiety (I).

M. Shiozaki, Y. Kobayashi, H. Miyazaki, 2010 .

SYNTHESIS OF 5-e/?z-TREHAZOLIN (TREHALOSTATIN)

M. Shiozaki, Hideki, Yoshiyuki, 2006 .

Synthesis of Trehazolin β‐Anomer.

M. Shiozaki, Y. Kobayashi, 1994 .

Syntheses of Trehazolin, Trehalamine, and the Aminocyclitol Moiety of Trehazolin: Determination of Absolute Configuration of Trehazolin.

Yoshiyuki Kobayashi, M. Shiozaki, H. Miyazaki, 1994 .

Syntheses and Absolute Configurations of Trehazolin and Its Aglycon.

Yoshiyuki Kobayashi, M. Shiozaki, H. Miyazaki, 1993 .

Synthesis of 5‐epi‐Trehazolin (Trehalostatin).

H. Haruyama, Yoshiyuki Kobayashi, M. Shiozaki, 1995 .

Synthesis and Biological Activity of 4′,8-Dihydroxyisoflavon-7-yl D-Hexopyranosides.

M. Shiozaki, Yukiko Watanabe, R. Kamegai, 2002 .

Synthesis of 4′,8‐Dihydroxyisoflavon‐7‐yl α‐D‐Arabinofuranoside.

M. Shiozaki, 1999 .

Synthesis of GLA-60 Positional Isomer as an LPS-Agonist and Its Activity

M. Nishijima, H. Maeda, M. Shiozaki, 1996 .

Syntheses of glucose derivatives of E5564-related compounds and their LPS-antagonistic activities.

M. Shiozaki, T. Shimozato, D. Tanaka, 2006, Carbohydrate research.

Stereoselective synthesis of d-erythro-sphingosine and l-lyxo-phytosphingosine

Tsuyoshi Nakamura, M. Shiozaki, 2001 .

Preparation of 3,6-di-O-benzylallosamizoline from natural allosamidin

M. Shiozaki, Takanori Wakabayashi, H. Saito, 2000 .

An alternative synthesis of d-erythro-sphingosine and l-lyxo-phytosphingosine

Tsuyoshi Nakamura, M. Shiozaki, 1999 .

Stereoselective Synthesis of D-erythro-Sphingosine and L-lyxo-Phytosphingosine.

Tsuyoshi Nakamura, M. Shiozaki, 2002 .

An Alternative Synthesis of D-erythro-Sphingosine and L-lyxo-Phytosphingosine.

Tsuyoshi Nakamura, M. Shiozaki, 2000 .

Revised structure and synthesis of flavolipin

Y. Kawai, M. Nishijima, H. Haruyama, 1998 .

Revised structure of flavolipin and synthesis of its isomers

Y. Kawai, M. Nishijima, H. Haruyama, 1998 .

Stereocontrolled synthesis of all stereoisomers of the proposed flavolipin

M. Nishijima, M. Shiozaki, T. Mochizuki, 1996 .

Synthesis of (6R,7R)‐D‐Gluco‐L‐gulo‐6,7‐Dodecodiulose‐(6,2),(7,11).

M. Shiozaki, T. Mochizuki, 1997 .

Synthesis of (6R,7R)-D-gluco-L-gulo-6,7-dodecodiulose-(6,2),(7,11)

M. Shiozaki, T. Mochizuki, 1997 .

Revised Structure of Flavolipin and Synthesis of Its Isomers.

Y. Kawai, M. Nishijima, H. Haruyama, 1998 .

Revised Structure and Synthesis of Flavolipin.

Y. Kawai, M. Nishijima, H. Haruyama, 1999 .

Stereocontrolled Synthesis of All Stereoisomers of the Proposed Flavolipin.

M. Nishijima, M. Shiozaki, T. Mochizuki, 1996 .

Lipid A-Type Pyrancarboxylic Acid Derivatives, their Synthesis and their Biological Activities

M. Nishijima, M. Shiozaki, T. Mochizuki, 2000 .

Cleavage and some modifications of the 7-amide group of the cephamycins

M. Shiozaki, T. Hiraoka, K. Iino, 1980 .

A new method for cleavage of 7-amide group of cephalosporins

M. Shiozaki, T. Hiraoka, K. Iino, 1978 .

Conversion of D‐Glucose to L‐Glucose: Oxidative Decarboxylation of . alpha.‐Oxy Carboxylic Acids via Their Diacyl Peroxides.

M. Shiozaki, 1991 .

Synthesis of (.+-.)-threo-3-[(benzyloxycarbonyl)oxy]-2-fluorotetradecanoic acid

M. Shiozaki, M. Arai, 1989 .

Syntheses of glucose-containing E5564 analogues and their LPS-antagonistic activities

M. Shiozaki, T. Shimozato, D. Tanaka, 2006 .

Synthesis of ceramidated GLA-60 derivatives.

Tsuyoshi Nakamura, M. Shiozaki, S. Kurakata, 2002, Carbohydrate research.

Syntheses of glucose analogues of E5564 as a highly potent anti-sepsis drug candidate.

M. Shiozaki, T. Shimozato, Hiromi Doi, 2006, Bioorganic & medicinal chemistry.

Syntheses of Glucose-Containing Lipid A Analogues and Their LPS-Antagonistic Activities

M. Shiozaki, T. Shimozato, Hiromi Doi, 2005 .

Synthesis of lipid A analogues containing glucose instead of glucosamine and their LPS-antagonistic activities

M. Shiozaki, T. Shimozato, Hiromi Doi, 2005 .

Synthesis of lipid A type pyran carboxylic acids with ether chains and their biological activities.

M. Nishijima, M. Shiozaki, Y. Watanabe, 2001, Carbohydrate research.

Synthesis of the thienamycin nucleus: A synthesis of (.+-.)-diethyl 3-benzylthio-7-oxo-1-azabicyclo(3.2.0)hept-3-ene-2,2-bis(carboxylate).

M. Shiozaki, T. Hiraoka, N. Ishida, 1982 .