T. Shinomura

发表

Multiple Forms of Mouse PG-M, a Large Chondroitin Sulfate Proteoglycan Generated by Alternative Splicing (*)

K. Ito, K. Kimata, M. Zako, 1995, The Journal of Biological Chemistry.

Versican V1 isoform regulates cell‐associated matrix formation and cell behavior differentially from aggrecan in Swarm rat chondrosarcoma cells

N. Ishiguro, Y. Nishida, S. Tsukushi, 2012, International journal of cancer.

A heparin-binding growth factor, midkine, binds to a chondroitin sulfate proteoglycan, PG-M/versican.

K. Zou, T. Muramatsu, K. Kimata, 2000, European journal of biochemistry.

Gene expression of type II collagen is regulated by direct interaction with Kruppel-like factor 4 and AT-rich interactive domain 5B.

X. Zhang, T. Shinomura, Giang Thi Hien Nham, 2020, Gene.

Development and application of a new Silent reporter system to quantitate the activity of enhancer elements in the type II Collagen Gene.

T. Shinomura, Kazuo Ito, 2016, Gene.

A newly identified enhancer element responsible for type II collagen gene expression.

J. Kimura, M. Höök, T. Shinomura, 2012, Journal of biochemistry.

Screening for genes preferentially expressed in the early phase of chondrogenesis.

J. Kimura, M. Höök, T. Shinomura, 2006, Biochemical and biophysical research communications.

Proteoglycan-Lb, a small dermatan sulfate proteoglycan expressed in embryonic chick epiphyseal cartilage, is structurally related to osteoinductive factor.

K. Kimata, T. Shinomura, 1992, The Journal of biological chemistry.

Molecular cloning of the mouse osteoglycin-encoding gene.

K. Kimata, T. Shinomura, M. Ujita, 1995, Gene.

Identification and Characterization of Versican/PG-M Aggregates in Cartilage*

K. Shimizu, Kazuaki Matsumoto, Yoshihiko Yamada, 2006, Journal of Biological Chemistry.

Impaired dental implant osseointegration in rat with streptozotocin-induced diabetes.

K. Mizutani, T. Hanawa, K. Takeda, 2022, Journal of periodontal research.

Distinct Interaction of Versican/PG-M with Hyaluronan and Link Protein*

M. Shionyu, K. Shimizu, Kazuaki Matsumoto, 2003, Journal of Biological Chemistry.

Versican V1 in human endometrial epithelial cells promotes BeWo spheroid adhesion in vitro.

T. Baba, I. Konishi, E. Kondoh, 2019, Reproduction.

Three Isoforms of Mammalian Hyaluronan Synthases Have Distinct Enzymatic Properties*

P. Lenas, M. Hamaguchi, J. McDonald, 1999, The Journal of Biological Chemistry.

Expression of PG-M(V3), an Alternatively Spliced Form of PG-M without a Chondroitin Sulfate Attachment Region in Mouse and Human Tissues (*)

K. Ito, K. Kimata, M. Zako, 1995, The Journal of Biological Chemistry.

Abnormal occurrence of a large chondroitin sulfate proteoglycan, PG-M/versican in osteoarthritic cartilage.

Y. Nishida, K. Kimata, H. Iwata, 1994, Osteoarthritis and cartilage.

Gene trap screening for cell surface and extracellular matrix molecules produced by chondrocytes.

T. Muneta, S. Shirasawa, J. Kimura, 2005, Journal of biochemistry.

Expression and localization of PG‐Lb/epiphycan during mouse development

G. Pinero, M. Höök, T. Shinomura, 1999, Developmental dynamics : an official publication of the American Association of Anatomists.

Forced expression of KIAA1199, a novel hyaluronidase, inhibits tumorigenicity of low-grade chondrosarcoma.

T. Ushida, H. Koike, N. Ishiguro, 2020, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Suppression of hyaluronan synthesis attenuates the tumorigenicity of low‐grade chondrosarcoma

T. Ushida, H. Koike, N. Ishiguro, 2018, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Total synthesis of a gene for octopus rhodopsin and its preliminary expression.

T. Sakamoto, T. Shinomura, T. Senda, 1991, Journal of biochemistry.

cDNA cloning of PG-M, a large chondroitin sulfate proteoglycan expressed during chondrogenesis in chick limb buds. Alternative spliced multiforms of PG-M and their relationships to versican.

K. Ito, Y. Nishida, K. Kimata, 1993, The Journal of biological chemistry.

Structural analysis of chick-embryo cartilage proteoglycan by selective degradation with chondroitin lyases (chondroitinases) and endo-beta-D-galactosidase (keratanase).

K. Nakazawa, S. Suzuki, K. Kimata, 1980, The Biochemical journal.

Syndecans Reside in Sphingomyelin-Enriched Low-Density Fractions of the Plasma Membrane Isolated from a Parathyroid Cell Line

Tomoko Kimura, K. A. Podyma-Inoue, M. Yanagishita, 2012, PloS one.

The distribution of mesenchyme proteoglycan (PG-M) during wing bud outgrowth

M. Yamagata, K. Kimata, M. Solursh, 2004, Anatomy and Embryology.

Transient Expression of PG‐M/Versican, a Large Chondroitin Sulfate Proteoglycan in Developing Chicken Retina

K. Kimata, M. Zako, M. Iwaki, 1997, Journal of neurochemistry.

Spatio‐temporal expression of activating transcription factor 5 in the skeletal development of mouse limb

T. Ogino, M. Takagi, T. Shinomura, 2009, Development, growth & differentiation.

Follicular dendritic cell-secreted protein is decreased in experimental periodontitis concurrently with the increase of interleukin-17 expression and the Rankl/Opg mRNA ratio.

Y. Sugita, T. Kubo, Y. Iwamura, 2014, Journal of periodontal research.

Leucine-rich repeat glycoproteins of the extracellular matrix.

T. Shinomura, A. Hocking, D. McQuillan, 1998, Matrix biology : journal of the International Society for Matrix Biology.

Occurrence of PG-Lb, a leucine-rich small chondroitin/dermatan sulphate proteoglycan in mammalian epiphyseal cartilage: molecular cloning and sequence analysis of the mouse cDNA.

K. Kurita, K. Kimata, M. Zako, 1996, The Biochemical journal.

Tissue variation of two large chondroitin sulfate proteoglycans (PG-M/versican and PG-H/aggrecan) in chick embryos

M. Yamagata, K. Kimata, T. Shinomura, 1993, Anatomy and Embryology.

Laminin A, B1, and B2 Chain Gene Expression in Transected and Regenerating Nerves: Regulation by Axonal Signals

G. Sobue, Yoshihiko Yamada, M. Doyu, 1993, Journal of neurochemistry.

Localization and expression pattern of amelotin, odontogenic ameloblast-associated protein and follicular dendritic cell-secreted protein in the junctional epithelium of inflamed gingiva

T. Kurita-Ochiai, Y. Ogata, Y. Nakayama, 2016, Odontology.

Appearance of distinct types of proteoglycan in a well-defined temporal and spatial pattern during early cartilage formation in the chick limb.

N. Maeda, K. Kimata, T. Shinomura, 1984, Developmental biology.

Isolation and characterization of a third proteoglycan (PG-Lt) from chick embryo cartilage which contains disulfide-bonded collagenous polypeptide.

N. Maeda, S. Suzuki, K. Kimata, 1983, The Journal of biological chemistry.

[18] Biosynthesis of cartilage proteoglycan and link protein

J. Kimura, T. Shinomura, E. J. Thonar, 1987 .

Versican/PG-M Regulates Chondrogenesis as an Extracellular Matrix Molecule Crucial for Mesenchymal Condensation*

K. Shimizu, N. Kamiya, K. Kimata, 2006, Journal of Biological Chemistry.

2B1 antigen characteristically expressed on extracellular matrices of human malignant tumors is a large chondroitin sulfate proteoglycan, PG-M/versican.

D. Heinegård, T. Tsuji, K. Kimata, 1996, Cancer research.

The Gene Structure and Organization of Mouse PG-M, a Large Chondroitin Sulfate Proteoglycan

K. Kimata, M. Zako, T. Shinomura, 1995, The Journal of Biological Chemistry.

Precartilage Condensation during Skeletal Pattern Formation

K. Kimata, T. Shinomura, 1990, Development, growth & differentiation.

A mapping technique for probing the structure of proteoglycan core molecules.

S. Suzuki, K. Kimata, T. Shinomura, 1982, The Journal of biological chemistry.

Proteinase activity in chondroitin lyase (chondroitinase) and endo-beta-D-galactosidase (keratanase) preparations and a method to abolish their proteolytic effect on proteoglycan.

S. Suzuki, K. Kimata, T. Shinomura, 1980, The Biochemical journal.

Identification of genes preferentially expressed in periodontal ligament: specific expression of a novel secreted protein, FDC-SP.

S. Iseki, I. Ishikawa, T. Terashima, 2005, Biochemical and biophysical research communications.

Lipopolysaccharide induces rapid loss of follicular dendritic cell-secreted protein in the junctional epithelium.

S. Iseki, T. Terashima, T. Terashima, 2012, Journal of periodontal research.

Adsorption of Follicular Dendritic Cell-secreted Protein (FDC-SP) onto Mineral Deposits

S. Shirasawa, J. Kimura, M. Höök, 2008, Journal of Biological Chemistry.

Possible Repositioning of an Oral Anti-Osteoporotic Drug, Ipriflavone, for Treatment of Inflammatory Arthritis via Inhibitory Activity of KIAA1199, a Novel Potent Hyaluronidase

K. Ohno, T. Ushida, H. Koike, 2022, International journal of molecular sciences.

Expression of type II collagen and aggrecan genes is regulated through distinct epigenetic modifications of their multiple enhancer elements.

Y. Asou, T. Shinomura, Giang Thi Hien Nham, 2019, Gene.

A candidate enhancer element responsible for high-level expression of the aggrecan gene in chondrocytes.

Y. Izumi, Y. Ikeda, T. Shinomura, 2014, Journal of biochemistry.

The occurrence of three different proteoglycan species in chick embryo cartilage. Isolation and characterization of a second proteoglycan (PG-Lb) and its precursor form.

S. Suzuki, K. Kimata, T. Shinomura, 1983, The Journal of biological chemistry.

Phenotypic characterization of epiphycan-deficient and epiphycan/biglycan double-deficient mice.

R. Behringer, D. Keene, M. Young, 2010, Osteoarthritis and cartilage.

Expression and binding activity of the carboxyl-terminal portion of the core protein of PG-M, a large chondroitin sulfate proteoglycan.

K. Ito, K. Kimata, T. Shinomura, 1994, The Journal of biological chemistry.

Molecular Cloning and Expression of Chick Chondrocyte Chondroitin 6-Sulfotransferase (*)

Megumi Kato, K. Kimata, T. Shinomura, 1995, The Journal of Biological Chemistry.

Avian neural crest cell migration is diversely regulated by the two major hyaluronan-binding proteoglycans PG-M/versican and aggrecan.

M. Mörgelin, A. Colombatti, M. Bronner‐Fraser, 2000, Development.

Versican/PG-M is essential for ventricular septal formation subsequent to cardiac atrioventricular cushion development.

N. Hiraiwa, E. Adachi, M. Kusakabe, 2012, Glycobiology.

Absence of Biglycan Accelerates the Degenerative Process in Mouse Intervertebral Disc

M. Young, T. Ogino, T. Shinomura, 2009, Spine.

Role of Versican in the Pathogenesis of Peritoneal Endometriosis.

I. Konishi, T. Shinomura, A. Horie, 2016, The Journal of clinical endocrinology and metabolism.

A large chondroitin sulfate proteoglycan (PG-M) synthesized before chondrogenesis in the limb bud of chick embryo.

M. Yamagata, S. Suzuki, K. Kimata, 1986, The Journal of biological chemistry.

Alternative Splicing of the Unique “PLUS” Domain of Chicken PG-M/Versican Is Developmentally Regulated*

K. Kimata, M. Zako, T. Shinomura, 1997, The Journal of Biological Chemistry.

Localization and expression pattern of amelotin, odontogenic ameloblast-associated protein and follicular dendritic cell-secreted protein in the junctional epithelium of inflamed gingiva

T. Kurita-Ochiai, Y. Ogata, Y. Nakayama, 2017, Odontology.

Establishment of a novel chondrocyte‐like cell line derived from transgenic mice harboring the temperature‐sensitive simian virus 40 large T‐antigen gene

N. Mataga, M. Obinata, M. Noda, 1996, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Identification of genes preferentially expressed in articular cartilage by suppression subtractive hybridization.

Y. Ikawa, S. Shirasawa, Sayaka Nakamura, 2005, Journal of medical and dental sciences.

Xylosyl transfer to the core protein precursor of the rat chondrosarcoma proteoglycan.

V. Hascall, J. Kimura, T. Shinomura, 1989, The Journal of biological chemistry.

Characterization of an anti-decorin monoclonal antibody, and its utility.

T. Tsuji, K. Kimata, T. Shinomura, 2002, Journal of biochemistry.

Phenotypic characterization of epiphycan-deficient and epiphycan/biglycan double-deficient mice.

T. Shinomura, Wei Zhou, Ying Wang, 2010, Osteoarthritis and cartilage.