E. Shores

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T Cell Development in Mice Lacking All T Cell Receptor ζ Family Members (ζ, η, and FcεRIγ)

M. Ono, J. Ravetch, M. Udey, 1998, The Journal of experimental medicine.

Recommendations for the design and optimization of immunoassays used in the detection of host antibodies against biotechnology products.

George Scott, Viswanath Devanarayan, Gopi Shankar, 2004, Journal of immunological methods.

Neutralizing antibodies to therapeutic enzymes: considerations for testing, prevention and treatment

Anne R. Pariser, A. Pariser, A. Rosenberg, 2008, Nature Biotechnology.

T cell development in mice that lack the zeta chain of the T cell antigen receptor complex.

A. Singer, M. Tremblay, H. Westphal, 1993, Science.

Requirement for NF-kappaB in osteoclast and B-cell development.

A. Leonardi, L. Carlson, L. Xing, 1997, Genes & development.

Fine Tuning of TCR Signaling by CD5

C. Park, P. Love, C. Sommers, 2001, The Journal of Immunology.

TCR ζ chain in T cell development and selection

P. Love, E. Shores, 1997 .

Characterization of an associated 16-kDa tyrosine phosphoprotein required for Ly-49D signal transduction.

S. Anderson, J. Ortaldo, P. Love, 1998, Journal of immunology.

ITAM multiplicity and thymocyte selection: how low can you go?

P. Love, E. Shores, Paul E. Love, 2000, Immunity.

In vivo calcium elevations in thymocytes with T cell receptors that are specific for self ligands.

C. June, A. Singer, T. Nakayama, 1992, Science.

Requirement for NF-kB in osteoclast and B-cell development

A. Leonardi, L. Carlson, L. Xing, 1997 .

Negative selection of precursor thymocytes before their differentiation into CD4+CD8+ cells.

A. Singer, Y. Takahama, E. Shores, 1992, Science.

An architectural perspective on signaling by the pre‐, αβ and γδ T cell receptors

P. Love, E. Shores, S. Hayes, 2003, Immunological reviews.

Mutation of the phospholipase C-γ1–binding site of LAT affects both positive and negative thymocyte selection

L. Samelson, C. DePersis, P. Love, 2005, The Journal of experimental medicine.

Role of the Common Cytokine Receptor γ Chain in Cytokine Signaling and Lymphoid Development

W. Leonard, P. Love, E. Shores, 1995, Immunological reviews.

Ly-49 D Signal Transduction 16-kDa Tyrosine Phosphoprotein Required for Cutting Edge : Characterization of an Associated

S. Anderson, J. Ortaldo, P. Love, 1998 .

T cell receptor‐negative thymocytes from SCID mice can be induced to enter the CD4/CD8 differentiation pathway

A. Singer, S. Sharrow, E. Shores, 1990, European journal of immunology.

Disorganization and restoration of thymic medullary epithelial cells in T cell receptor‐negative scid mice: Evidence that receptor‐bearing lymphocytes influence maturation of the thymic microenvironment

A. Singer, W. van Ewijk, E. Shores, 1991, European journal of immunology.

Developmentally regulated expression of CD3 components independent of clonotypic T cell antigen receptor complexes on immature thymocytes

A. Singer, D. Wiest, K. Kearse, 1994, The Journal of experimental medicine.

A LAT Mutation That Inhibits T Cell Development Yet Induces Lymphoproliferation

L. Samelson, C. Feng, A. Grinberg, 2002, Science.

Requirement for NF- (cid:107) B in osteoclast and B-cell development

A. Leonardi, L. Carlson, L. Xing, 1997 .

Specific requirement for CD3epsilon in T cell development.

K. Katz, P. Love, K. Woodside, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Crosstalk in the mouse thymus.

A. Singer, W. Ewijk, W. van Ewijk, 1994, Immunology today.

Presence of CD4 and CD8 determinants on CD4−CD8− murine thymocytes: passive acquisition of CD8 accessory molecules

A. Singer, S. Sharrow, E. Shores, 1991, European journal of immunology.

Cellular interactions for the in vitro production of anti-chromatin autoantibodies in MRL/Mp-lpr/lpr mice.

C. Fisher, R. Eisenberg, P. Cohen, 1989, Clinical immunology and immunopathology.

Critical Relationship Between TCR Signaling Potential and TCR Affinity During Thymocyte Selection

P. Love, E. Shores, Jan-Mou Lee, 2000, The Journal of Immunology.

Thymocyte Selection Potential and TCR Affinity During Critical Relationship Between TCR Signaling

P. Love, Jan Lee, E. Shores, 2000 .

Role of the Multiple T Cell Receptor (TCR)-ζ Chain Signaling Motifs in Selection of the T Cell Repertoire

A. Grinberg, P. Love, C. Sommers, 1997, The Journal of experimental medicine.

Regulation of TCR signal transduction in murine thymocytes by multiple TCR zeta-chain signaling motifs.

A. Weiss, P. Love, N. V. van Oers, 1998, Journal of immunology.

Mice Deficient in Nuclear Factor (NF)-κB/p52 Present with Defects in Humoral Responses, Germinal Center Reactions, and Splenic Microarchitecture

A. Leonardi, M. Anver, L. Carlson, 1998, The Journal of experimental medicine.

Delayed maturation of CD4- CD8- Fc gamma RII/III+ T and natural killer cell precursors in Fc epsilon RI gamma transgenic mice

J. Kinet, V. Flamand, A. Grinberg, 1996, The Journal of experimental medicine.

Delayed Maturation of C D 4C D 8-Fc ~ / RII / III + T and Natural Killer Cell Precursors in FceRI ~ / Transgenic Mice

J. Kinet, A. Grinberg, Eric M Lee, 2022 .

Developmental Arrest of T Cell Receptor (TcR) Negative SCID Thymocytes and Release in the Presence of TcR+ Cells

A. Singer, S. Sharrow, E. Shores, 1989 .

Qualitative and Quantitative Contributions of the T Cell Receptor ~ Chain To Mature T Cell Apoptosis

M. Lenardo, E. Shores, Lina Chen, 2003 .

Antiproliferative action of interferon-α requires components of T-cell-receptor signalling

E. Petricoin, A. Weiss, R. Abraham, 1997, Nature.

Murine txk: a protein tyrosine kinase gene regulated by T cell activation.

C. Kozak, A. Grinberg, P. Love, 1995, Oncogene.

Maturation of medullary thymic epithelium requires thymocytes expressing fully assembled CD3-TCR complexes.

A. Singer, W. Ewijk, W. van Ewijk, 1994, International immunology.

Antiproliferative action of interferon-alpha requires components of T-cell-receptor signalling.

E. Petricoin, A. Weiss, R. Abraham, 1997, Nature.

T Cell Development in Mice Lacking All T Cell Receptor z Family Members

M. Ono, M. Udey, P. Love, 1998 .

Function of Cd3ε-Mediated Signals in T Cell Development

P. Love, C. Sommers, Kun Huang, 2000, The Journal of experimental medicine.

Evaluation of the Inbred Mouse as a Model for Experimental Treponema pallidum Infection

J. Folds, E. Shores, J. Saunders, 1983, Scandinavian journal of immunology.

Function of CD3 e -mediated Signals in T Cell Development

P. Love, Jan Lee, C. Sommers, 2000 .

Role of the Sm antigen in the generation of anti-Sm autoantibodies in the SLE-prone MRL mouse.

R. Eisenberg, P. Cohen, E. Shores, 1986, Journal of immunology.

Recommendations on risk-based strategies for detection and characterization of antibodies against biotechnology products.

Viswanath Devanarayan, Boris Gorovits, Michael Moxness, 2008, Journal of immunological methods.

Requirement for NF-κB in osteoclast and B-cell development

Ulrich Siebenlist, Antonio Leonardi, A. Leonardi, 1997 .

Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.

W. Leonard, W. Paul, J. Drago, 1995, Immunity.

Role of TCR zeta chain in T cell development and selection.

A. Grinberg, E. Lee, P. Love, 1994, Science.

The Common Cytokine Receptor γ Chain Plays an Essential Role in Regulating Lymphoid Homeostasis

W. Leonard, M. Noguchi, H. Nakajima, 1997, The Journal of experimental medicine.

The Common Cytokine Receptor (cid:103) Chain Plays an Essential Role in Regulating Lymphoid Homeostasis

W. Leonard, M. Noguchi, H. Nakajima, 1997 .

A potential role for CD69 in thymocyte emigration.

C. Feng, B. Fowlkes, P. Love, 2002, International immunology.

Critical roles for the Bcl-3 oncoprotein in T cell-mediated immunity, splenic microarchitecture, and germinal center reactions.

A. Sher, A. Leonardi, M. Anver, 1997, Immunity.

Differential effects of zeta and eta transgenes on early alpha/beta T cell development

A. Singer, H. Westphal, A. Grinberg, 1994, The Journal of experimental medicine.

Anti-Sm autoantibodies in MRL mice: analysis of precursor frequency.

R. Eisenberg, P. Cohen, R. Rapoport, 1985, Cellular immunology.

Immunization with the Sm nuclear antigen induces anti-Sm antibodies in normal and MRL mice.

D. Pisetsky, R. Eisenberg, P. Cohen, 1988, Immunology.

Recommendations for the design, optimization, and qualification of cell-based assays used for the detection of neutralizing antibody responses elicited to biological therapeutics.

Marian Kelley, Eric Wakshull, A. Mire-Sluis, 2007, Journal of immunological methods.

CD5 Expression Is Developmentally Regulated By T Cell Receptor (TCR) Signals and TCR Avidity

A. Grinberg, P. Love, E. Shores, 1998, The Journal of experimental medicine.

Functional cleavage of the common cytokine receptor γ chain (γc) by calpain

W. Leonard, M. Noguchi, M. Aman, 1997 .

Scientific and regulatory considerations on the immunogenicity of biologics.

Gopi Shankar, A. Mire-Sluis, G. Shankar, 2006, Trends in biotechnology.

Qualitative and Quantitative Contributions of the T Cell Receptor ~ Chain to Mature T Cell Apoptosis

M. Lenardo, P. Love, L. Chen, 1996 .

Insights into T cell development and signal transduction provided by TCR-zeta chain deficient mice.

P. Love, E. Shores, 1996, International reviews of immunology.

Structurally distinct T cell receptor complexes on developmentally distinct T cell populations in severe combined immunodeficiency mice expressing a TCR beta transgene.

A. Singer, Y. Takahama, D. Wiest, 1993, Journal of immunology.

Expression of Mls determinants in mice exhibiting the severe combined immunodeficiency (scid) mutation or X-linked immunodeficiency (xid) defect.

J. Roberts, A. Singer, R. Abe, 1992, Journal of immunology.

T-B collaboration in the in vitro anti-Sm autoantibody response of MRL/Mp-lpr/lpr mice.

R. Eisenberg, P. Cohen, E. Shores, 1988, Journal of Immunology.

Specific requirement for CD3ɛ in T cell development

K. Katz, P. Love, K. Woodside, 1998 .

Fc epsilonRI gamma can support T cell development and function in mice lacking endogenous TCR zeta-chain.

J. Kinet, V. Flamand, A. Grinberg, 1997, Journal of immunology.

MirandadirectsProspero toadaughtercell during Drosophila asymmetric divisions

R. Abraham, L. Stancato, A. Gamero, 1997 .

The Common Cytokine Receptor γ Chain Plays an Essential Role in Regulating Lymphoid Homeostasis

W. Leonard, M. Noguchi, H. Nakajima, 1997, The Journal of experimental medicine.

Qualitative and quantitative contributions of the T cell receptor zeta chain to mature T cell apoptosis

B. Combadière, E. Shores, Michael J. Lenardo, 1996, The Journal of experimental medicine.

The Common Cytokine Receptor (cid:103) Chain Plays an Essential Role in Regulating Lymphoid Homeostasis

E. Shores, Masayuki Noguchi, Warren J. Leonard, 1997 .

Delayed maturation of CD4- CD8- Fc gamma RII/III+ T and natural killer cell precursors in Fc epsilon RI gamma transgenic mice

J. Kinet, E. Shores, Alexander Grinberg, 1996, The Journal of experimental medicine.

Specific requirement for CD 3 « in T cell development

K. Katz, P. Love, K. Woodside, 1998 .