Guanghao Zhu

发表

Discovery and Characterization of the Naturally Occurring Inhibitors Against Human Pancreatic Lipase in Ampelopsis grossedentata

Guangbo Ge, Liangliang Zhu, Xiaodong Qin, 2022, Frontiers in Nutrition.

Discovery and characterization of naturally occurring chalcones as potent inhibitors of bile salt hydrolases

Chun Xing Li, Guangbo Ge, J. Hou, 2022, Acta Materia Medica.

Deciphering the Effective Constituents and Mechanisms of Portulaca oleracea L. for Treating NASH via Integrating Bioinformatics Analysis and Experimental Pharmacology

Y. Hu, Guanghao Zhu, Jin-gang Cui, 2022, Frontiers in Pharmacology.

Chemo- and Site-Selective Lysine Modification of Peptides and Proteins under Native Conditions Using the Water-Soluble Zolinium.

Weiliang Zhu, Kaixian Chen, Bo Li, 2022, Journal of medicinal chemistry.

The SARS‐CoV‐2 main protease (Mpro): Structure, function, and emerging therapies for COVID‐19

Yi-wen Zhang, Ping Huang, Guanghao Zhu, 2022, MedComm.

Discovery and mechanism of action of Thonzonium bromide from an FDA-approved drug library with potent and broad-spectrum inhibitory activity against main proteases of human coronaviruses

Guanghao Zhu, Mengge Wang, Lili Chen, 2022, Bioorganic Chemistry.

Identification of Vitamin K3 and its analogues as covalent inhibitors of SARS-CoV-2 3CLpro

Chun Xing Li, Hongzhuan Chen, Guangbo Ge, 2021, International Journal of Biological Macromolecules.

Discovery and Characterization of the Key Constituents in Ginkgo biloba Leaf Extract With Potent Inhibitory Effects on Human UDP-Glucuronosyltransferase 1A1

Tongyi Dou, Guangbo Ge, Guanghao Zhu, 2022, Frontiers in Pharmacology.

Super-Resolution Imaging of Autophagy by a Preferred Pair of Self-Labeling Protein Tags and Fluorescent Ligands.

Guanghao Zhu, Zhiwei Ye, Guangbo Ge, 2022, Analytical chemistry.

Discovery of naturally occurring inhibitors against SARS-CoV-2 3CLpro from Ginkgo biloba leaves via large-scale screening

Hong-Zhuan Chen, Guangbo Ge, Huiliang Li, 2021, Fitoterapia.

Flavonoids in Ampelopsis grossedentata as covalent inhibitors of SARS-CoV-2 3CLpro: Inhibition potentials, covalent binding sites and inhibitory mechanisms

Guangbo Ge, Guanghao Zhu, Yuan Xiong, 2021, International Journal of Biological Macromolecules.

Inhibition of Human UDP-Glucuronosyltransferases1A1–Mediated Bilirubin Glucuronidation by the Popular Flavonoids Baicalein, Baicalin, and Hyperoside Is Responsible for Herb (Shuang-Huang-Lian)-Induced Jaundice

Weimin Cai, Guanghao Zhu, Ping Yang, 2022, Drug Metabolism and Disposition.

The roles of serine hydrolases and serum albumin in alisol B 23-acetate hydrolysis in humans

Feng Zhang, Jing Hu, Guanghao Zhu, 2023, Frontiers in Pharmacology.

Functional Imaging and Inhibitor Screening of Human Pancreatic Lipase by a Resorufin-Based Fluorescent Probe

Guanghao Zhu, Meng-Ru Sun, Yuejuan Zheng, 2023, Biosensors.

Methylophiopogonanone A is a naturally occurring broad‐spectrum inhibitor against human UDP‐glucuronosyltransferases: Inhibition behaviours and implication in herb‐drug interactions

Guangbo Ge, Guanghao Zhu, Yunqing Song, 2021, Basic & clinical pharmacology & toxicology.

Discovery of seven-membered ring berberine analogues as highly potent and specific hCES2A inhibitors.

Zhijian Xu, Yong Zhang, K. Zou, 2023, Chemico-biological interactions.

Discovery of 4'-trifluoromethylchalcones as novel, potent and selective hCYP1B1 inhibitors without concomitant AhR activation.

Xiao-Bo Sun, Z. Dai, Guanghao Zhu, 2023, European journal of medicinal chemistry.

A novel TICT-based near-infrared fluorescent probe for light-up sensing and imaging of human serum albumin in real samples

Lai Wei, Guanghao Zhu, Guangbo Ge, 2022, Chinese Chemical Letters.

Emerging Pharmacotherapeutic Strategies to Overcome Undruggable Proteins in Cancer

Yuewen Yang, Guanghao Zhu, Hairong Zeng, 2023, International journal of biological sciences.

Discovery of Isojacareubin as a covalent inhibitor of SARS‐CoV‐2 main protease using structural and experimental approaches

Dongqing Wei, Guanghao Zhu, Abbas Saleem Khan, 2023, Journal of medical virology.

New bysspectin A derivatives as potent inhibitors of human carboxylesterase 2A.

Ping Xie, Bo Ma, Guanghao Zhu, 2023, European journal of medicinal chemistry.

Characterization of the glucuronidating pathway of pectolinarigenin, the major active constituent of the Chinese medicine Daji, in humans and its influence on biological activities.

Guanghao Zhu, Dongzhu Tu, Guangbo Ge, 2023, Journal of ethnopharmacology.