Yuan Xiong

发表

Discovery and Characterization of the Naturally Occurring Inhibitors Against Human Pancreatic Lipase in Ampelopsis grossedentata

Guangbo Ge, Liangliang Zhu, Xiaodong Qin, 2022, Frontiers in Nutrition.

Pentacyclic triterpenoid acids in Styrax as potent and highly specific inhibitors against human carboxylesterase 1A.

F. Zhang, Guangbo Ge, Yuan Xiong, 2020, Food & function.

AWARD NUMBER: W81XWH-16-1-0106 TITLE: Fragment-Based Approaches to Enhance GTP Competitive KRAS G12C Inhibitors PRINCIPAL INVESTIGATOR: Kenneth Westover CONTRACTING ORGANIZATION: University of Texas Southwestern Medical Center

David A. Scott, Kwok-Kin Wong, N. Gray, 2018 .

Human carboxylesterase 1A plays a predominant role in the hydrolytic activation of remdesivir in humans.

Feng Zhang, Hong-xin Li, Guangbo Ge, 2021, Chemico-biological interactions.

The SARS‐CoV‐2 main protease (Mpro): Structure, function, and emerging therapies for COVID‐19

Yi-wen Zhang, Ping Huang, Guanghao Zhu, 2022, MedComm.

Inhibition of pancreatic lipase by environmental xenoestrogens.

H. Yin, Guangbo Ge, Ling Yang, 2020, Ecotoxicology and environmental safety.

Potent and Selective Covalent Quinazoline Inhibitors of KRAS G12C.

David A. Scott, P. Jänne, Kwok-Kin Wong, 2017, Cell chemical biology.

Discovery of naturally occurring inhibitors against SARS-CoV-2 3CLpro from Ginkgo biloba leaves via large-scale screening

Hong-Zhuan Chen, Guangbo Ge, Huiliang Li, 2021, Fitoterapia.

Discovery of 9,10-dihydrophenanthrene derivatives as SARS-CoV-2 3CLpro inhibitors for treating COVID-19

Xiaodi Yang, Guangbo Ge, Dingding Gao, 2021, European Journal of Medicinal Chemistry.

Structure-Guided Design of a "Bump-and-Hole" Bromodomain-Based Degradation Tag.

E. Fischer, R. Nowak, K. Donovan, 2021, Journal of medicinal chemistry.

Chemo-proteomics exploration of HDAC degradability by small molecule degraders.

A. Razov, E. Fischer, R. Nowak, 2021, Cell chemical biology.

Exploring Targeted Degradation Strategy for Oncogenic KRASG12C.

David A. Scott, P. Jänne, N. Gray, 2019, Cell chemical biology.

Covalent Guanosine Mimetic Inhibitors of G12C KRAS.

Taebo Sim, Sang Min Lim, John Hunter, 2017, ACS medicinal chemistry letters.

Flavonoids in Ampelopsis grossedentata as covalent inhibitors of SARS-CoV-2 3CLpro: Inhibition potentials, covalent binding sites and inhibitory mechanisms

Guangbo Ge, Guanghao Zhu, Yuan Xiong, 2021, International Journal of Biological Macromolecules.

Discovery of seven-membered ring berberine analogues as highly potent and specific hCES2A inhibitors.

Zhijian Xu, Yong Zhang, K. Zou, 2023, Chemico-biological interactions.

Discovery of 4'-trifluoromethylchalcones as novel, potent and selective hCYP1B1 inhibitors without concomitant AhR activation.

Xiao-Bo Sun, Z. Dai, Guanghao Zhu, 2023, European journal of medicinal chemistry.

CYP1A inhibitors: Recent progress, current challenges, and future perspectives.

Xiaobo Sun, Ziru Dai, Min Wang, 2023, Medicinal research reviews.