J. Leigh

发表

Complete Genome Sequence of Streptococcus agalactiae Strain 01173, Isolated from Kuwaiti Wild Fish

D. Verner-Jeffreys, Morena Santi, S. Egan, 2020, Microbiology Resource Announcements.

Identification and Disruption of Two Discrete Loci Encoding Hyaluronic Acid Capsule Biosynthesis GeneshasA, hasB, and hasC inStreptococcus uberis

E. Maguin, J. Leigh, P. Ward, 2001, Infection and Immunity.

Streptococcus uberis strains isolated from the bovine mammary gland evade immune recognition by mammary epithelial cells, but not of macrophages

O. Holst, J. Günther, H. Seyfert, 2016, Veterinary Research.

Multilocus-sequence typing analysis reveals similar populations of Streptococcus uberis are responsible for bovine intramammary infections of short and long duration.

M. Maiden, G. Pullinger, T. Coffey, 2007, Veterinary microbiology.

Identification of Streptococcus uberis Multilocus Sequence Types Highly Associated with Mastitis

G. Pullinger, B. Meehan, T. Tomita, 2007, Applied and Environmental Microbiology.

Application of Streptococcus uberis Multilocus Sequence Typing: Analysis of the Population Structure Detected among Environmental and Bovine Isolates from New Zealand and the United Kingdom

M. Maiden, G. Pullinger, J. Williamson, 2006, Applied and Environmental Microbiology.

Lipoprotein Signal Peptides Are Processed by Lsp and Eep of Streptococcus uberis

E. Denham, J. Leigh, P. Ward, 2008, Journal of bacteriology.

Partial purification, stereospecificity and stoichiometry of three dehalogenases from a Rhizobium species

R. Cooper, J. Leigh, A. Skinner, 1988 .

Changing and emerging pathogens.

J. Leigh, 2008 .

Localization of MtuA, an LraI homologue in Streptococcus uberis

J. Leigh, P. Ward, A. Smith, 2004, Journal of applied microbiology.

Identification of a Differentially Expressed Oligopeptide Binding Protein (OppA2) in Streptococcus uberis by Representational Difference Analysis of cDNA

L. Bowler, J. Leigh, P. Ward, 2003, Journal of bacteriology.

Differential Protein Expression in Streptococcus uberis under Planktonic and Biofilm Growth Conditions

H. Lappin-Scott, L. Bowler, R. C. Crowley, 2010, Applied and Environmental Microbiology.

Evidence for niche adaptation in the genome of the bovine pathogen Streptococcus uberis

B. Barrell, A. Bignell, M. Quail, 2009, BMC Genomics.

Hyperinvasive Neonatal Group B Streptococcus Has Arisen from a Bovine Ancestor

T. Peto, D. Crook, R. Harding, 2004, Journal of Clinical Microbiology.

Identification of genes required for the fitness of Streptococcus equi subsp. equi in whole equine blood and hydrogen peroxide

Amy K. Cain, D. Maskell, A. Waller, 2020, Microbial genomics.

Vru (Sub0144) controls expression of proven and putative virulence determinants and alters the ability of Streptococcus uberis to cause disease in dairy cattle

M. Watson, S. Egan, J. Leigh, 2012, Microbiology.

Hans-Martin (2016) Streptococcus uberis strains isolated from the bovine mammary gland evade immune recognition by mammary epithelial cells, but not of macrophages. Veterinary Research, 47 (13).

O. Holst, J. Günther, H. Seyfert, 2017 .

Development of the palatine tonsil in conventional and germ-free piglets.

K. Haverson, J. Leigh, M. Bailey, 2005, Developmental and comparative immunology.

Streptococcus agalactiae infection in dairy cows.

J. Hillerton, T. Coffey, J. Leigh, 2004, The Veterinary record.

Sortase anchored proteins of Streptococcus uberis play major roles in the pathogenesis of bovine mastitis in dairy cattle

T. Coffey, S. Egan, J. Leigh, 2010, Veterinary research.

Structural analysis of the lipoteichoic acids isolated from bovine mastitis Streptococcus uberis 233, Streptococcus dysgalactiae 2023 and Streptococcus agalactiae 0250.

O. Holst, B. Lindner, K. Duda, 2012, Carbohydrate research.

Streptococcus uberis: a permanent barrier to the control of bovine mastitis?

J. Leigh, James A. Leigh, 1999, Veterinary journal.

Two strains of Streptococcus uberis, of differing ability to cause clinical mastitis, differ in their ability to resist some host defence factors.

M. Williams, J. Leigh, T. R. Field, 1990, Research in veterinary science.

Molecular Epidemiology of Streptococcus uberis Clinical Mastitis in Dairy Herds: Strain Heterogeneity and Transmission

Richard D Emes, P. Davies, S. Archer, 2015, Journal of Clinical Microbiology.

Further studies on the efficacy of a live vaccine against mastitis caused by Streptococcus uberis.

A. Winter, J. Leigh, J. Finch, 1997, Vaccine.

The exploitation of the genome in the search for determinants of virulence in Streptococcus uberis.

J. Leigh, P. Ward, T. R. Field, 2004, Veterinary immunology and immunopathology.

Immune modification of the pathogenesis of Streptococcus uberis mastitis in the dairy cow.

J. Leigh, T. R. Field, J. Finch, 1994, FEMS immunology and medical microbiology.

MtuA, a Lipoprotein Receptor Antigen from Streptococcus uberis, Is Responsible for Acquisition of Manganese during Growth in Milk and Is Essential for Infection of the Lactating Bovine Mammary Gland

J. Leigh, P. Ward, T. R. Field, 2003, Infection and Immunity.

The Hyaluronic Acid Capsule of Streptococcus uberis Is Not Required for the Development of Infection and Clinical Mastitis

J. Leigh, P. Ward, T. R. Field, 2003, Infection and Immunity.

The interaction of Streptococcus dysgalactiae with plasmin and plasminogen.

S. Hodgkinson, J. Leigh, R. Lincoln, 1998, Veterinary microbiology.

The Auxotrophic Nature of Streptococcus uberis

J. Leigh, A. Kitt, 1997 .

Materials and Methods Bacterial strains and growth conditions

J. Leigh, James. A. Leigh, 2002 .

Purification of a plasminogen activator from Streptococcus uberis.

J. Leigh, 1994, FEMS microbiology letters.

Intrageneric structure of Streptococcus based on comparative analysis of small-subunit rRNA sequences.

R. W. Bentley, M. Collins, J. Leigh, 1991, International journal of systematic bacteriology.

PIMMS (Pragmatic Insertional Mutation Mapping System) Laboratory Methodology a Readily Accessible Tool for Identification of Essential Genes in Streptococcus

Richard D Emes, Andrew Warry, S. Egan, 2016, Front. Microbiol..

Field observations on the variation of Streptococcus uberis populations in a pasture-based dairy farm.

G. Pullinger, J. Williamson, S. Lacy-Hulbert, 2007, Journal of dairy science.

Interactions between Streptococcus suis serotype 2 and cells of the myeloid lineage in the palatine tonsil of the pig.

K. Haverson, J. Leigh, M. Bailey, 2007, Veterinary immunology and immunopathology.

The bio-physics of condensation of divalent cations into the bacterial wall has implications for growth of Gram-positive bacteria.

M. Cherkaoui, C. Rauch, S. Egan, 2017, Biochimica et biophysica acta. Biomembranes.

Rauch, Cyril and Cherkaoui-Rbati, Mohammed and Egan, Sharon A. and Leigh, James A. (2017) The bio- physics of condensation of divalent cations into the bacterial wall has implications for growth of Gram-

M. Cherkaoui, C. Rauch, S. Egan, 2017 .

condensation of divalent cations into the bacterial wall has 2 implications for growth of Gram-positive bacteria 3 4

M. Cherkaoui, C. Rauch, S. Egan, 2016 .

Identification of single nucleotide polymorphisms in the bovine Toll-like receptor 1 gene and association with health traits in cattle

T. Coffey, J. Leigh, S. Widdison, 2012, Veterinary Research.

In the absence of Lgt, lipoproteins are shed from Streptococcus uberis independently of Lsp.

E. Denham, J. Leigh, P. Ward, 2009, Microbiology.

Vaccination with the plasminogen activator from Streptococcus uberis induces an inhibitory response and protects against experimental infection in the dairy cow.

S. Hodgkinson, A. Winter, J. Leigh, 1999, Vaccine.

Richard D Emes, Ray Wilson, Maqsud Hossain, 2015, BMC Genomics.

An investigation of the suitability of three support matrices for the culture of cells derived from the secretory alveoli of the bovine mammary gland

J. Leigh, W. Ditcham, A. Bland, 2005, Veterinary Research Communications.

Early, microbially driven follicular reactions in the neonatal piglet do not contribute to expansion of the immunoglobulin heavy chain V-D-J repertoire.

J. Leigh, M. Bailey, Stephen Wilson, 2007, Veterinary immunology and immunopathology.

Adherence and colonization by bacterial pathogens in explant cultures of bovine mammary tissue

R. Cook, J. Leigh, A. Bland, 1992, Veterinary Research Communications.

Rapid Evolution of Virulence and Drug Resistance in the Emerging Zoonotic Pathogen Streptococcus suis

I. Goodhead, M. Quail, K. Mungall, 2009, PloS one.

Structural consideration of the formation of the activation complex between the staphylokinase-like streptococcal plasminogen activator PadA and bovine plasminogen.

A. Abu-Median, J. Leigh, P. Ward, 2008, Journal of molecular biology.

Production of extracellular proteases from Staphylococcusaureus strain V8 in dialysis culture

J. Leigh, R. Lincoln, 1994 .

First Insights into the Evolution of Streptococcus uberis: a Multilocus Sequence Typing Scheme That Enables Investigation of Its Population Biology

Keith A. Jolley, James A. Leigh, M. Maiden, 2006, Applied and Environmental Microbiology.

DNA fingerprinting of Streptococcus uberis: a useful tool for epidemiology of bovine mastitis

J. Leigh, A. W. Hill, 1989, Epidemiology and Infection.

Identification of sortase A (SrtA) substrates in Streptococcus uberis: evidence for an additional hexapeptide (LPXXXD) sorting motif.

L. Hunt, S. Egan, J. Leigh, 2010, Journal of proteome research.

Characterization of a novel plasminogen activator from Streptococcus uberis.

J. Leigh, R. Lincoln, 1997, Advances in experimental medicine and biology.

Development of PCR-based hybridization protocol for identification of streptococcal species

R. W. Bentley, J. Leigh, 1995, Journal of clinical microbiology.

A Staphylococcus aureus‐specific oligonucleotide probe derived from 16S rRNA gene sequences

R. W. Bentley, M. D. Collins, J. Leigh, 1993, Letters in applied microbiology.

Isolation and partial characterisation of dehalogenase-deficient mutants of a Rhizobium sp.

R. Cooper, J. Leigh, A. Skinner, 1986 .

Streptococcus uberis resists the bactericidal action of bovine neutrophils despite the presence of bound immunoglobulin

J. Leigh, T. R. Field, 1994, Infection and immunity.

Defining the ABC of gene essentiality in streptococci

Amy K. Cain, J. Parkhill, D. Maskell, 2017, BMC Genomics.

Transposon insertion mapping with PIMMS – Pragmatic Insertional Mutation Mapping System

Richard D. Emes, Richard D Emes, Adam M. Blanchard, 2015, Front. Genet..

The amino acid requirements of Staphylococcus aureus isolated from cases of bovine mastitis.

J. Leigh, R. Lincoln, N. C. Jones, 1995, Veterinary microbiology.

Development and use of species-specific oligonucleotide probes for differentiation of Streptococcus uberis and Streptococcus parauberis

R. W. Bentley, M. Collins, J. Leigh, 1993, Journal of clinical microbiology.

Development of a Multilocus Sequence Typing Scheme for the Pig Pathogen Streptococcus suis: Identification of Virulent Clones and Potential Capsular Serotype Exchange

Christopher G. Dowson, James A. Leigh, C. Dowson, 2002, Journal of Clinical Microbiology.

Local vaccination with killed Streptococcus uberis protects the bovine mammary gland against experimental intramammary challenge with the homologous strain

J. Leigh, T. R. Field, J. Finch, 1994, Infection and immunity.

Levels of Water-Soluble Vitamins in Methanogenic and Non-Methanogenic Bacteria

J. Leigh, 1983, Applied and environmental microbiology.

Complex interactions between bovine plasminogen and streptococcal plasminogen activator PauA.

A. Abu-Median, J. Leigh, P. Ward, 2004, Journal of molecular biology.

Theoretical evaluation of wall teichoic acids in the cavitation-mediated pores formation in Gram-positive bacteria subjected to an electric field.

C. Rauch, J. Leigh, 2015, Biochimica et biophysica acta.

Epithelial invasion and cell lysis by virulent strains of Streptococcus suis is enhanced by the presence of suilysin.

R. W. Bentley, C. Rolph, J. Leigh, 1999, FEMS immunology and medical microbiology.

PCR-Based Direct Detection of Streptococcus uberis from Subclinical and Clinical Dairy Cattle Milk Samples

T. Coffey, Morena Santi, S. Egan, 2020, Veterinary medicine international.

Genetic analysis of Streptococcus uberis plasminogen activators.

J. Leigh, P. Ward, 2004, The Indian journal of medical research.

Isolation and characterization of a mutant strain of Streptococcus uberis, which fails to utilize a plasmin derived β‐casein peptide for the acquisition of methionine

J. Leigh, P. Ward, A. Kitt, 2002, Journal of applied microbiology.

The Activation of Bovine Plasminogen by PauA Is Not Required for Virulence of Streptococcus uberis

J. Leigh, P. Ward, T. R. Field, 2003, Infection and Immunity.

Streptococcus uberis acquires plasmin activity following growth in the presence of bovine plasminogen through the action of its specific plasminogen activator.

J. Leigh, R. Lincoln, 1997, FEMS microbiology letters.

The auxotrophic nature of Streptococcus uberis. The acquisition of essential acids from plasmin derived casein peptides.

J. Leigh, A. Kitt, James A. Leigh, 1997, Advances in experimental medicine and biology.

Generation and Characterization of a Defined Mutant of Streptococcus suis Lacking Suilysin

D. Maskell, H. Lindsay, J. Leigh, 2001, Infection and Immunity.

Characterization of PauB, a Novel Broad-Spectrum Plasminogen Activator from Streptococcus uberis

J. Leigh, P. Ward, 2002, Journal of bacteriology.

Killing of Streptococcus uberis by bovine neutrophils following growth in chemically defined media

J. Leigh, T. R. Field, 2004, Veterinary Research Communications.

Assessment of the prevalence of Streptococcus uberis in dairy cow feces and implications for herd health.

Martin J. Green, S. Egan, J. Leigh, 2021, Journal of dairy science.

Survival of Streptococcus uberis on bedding substrates.

Martin J. Green, S. Egan, J. Leigh, 2021, Veterinary journal.

Development of gene probes for the specific identification of Streptococcus uberis and Streptococcus parauberis based upon large subunit rRNA gene sequences.

M. Collins, J. Leigh, N. Harland, 1993, The Journal of applied bacteriology.

Rauch, Cyril and Leigh, James A. (2014) Theoretical evaluation of wall teichoic acids in the cavitation- mediated pores formation in Gram-positive bacteria

C. Rauch, J. Leigh, 2017 .

Adhesion of Streptococcus uberis to monolayers of cultured epithelial cells derived from the bovine mammary gland.

J. Leigh, W. Ditcham, A. Bland, 1996, FEMS immunology and medical microbiology.

Host-response patterns of intramammary infections in dairy cows.

R. Zadoks, O. Holst, M. Fontaine, 2011, Veterinary immunology and immunopathology.

Identification of multiple linear epitopes of the plasminogen activator A (PauA) of Streptococcus uberis with murine monoclonal antibodies.

D. S. McVey, Jishu Shi, J. Leigh, 2005, Veterinary immunology and immunopathology.

PauA: a novel plasminogen activator from Streptococcus uberis.

J. Leigh, R. Yancey, P. Ward, 1999, FEMS microbiology letters.

Richard D Emes, Ray Wilson, Maqsud Hossain, 2015, BMC Genomics.

A Paradox in Bacterial Pathogenesis: Activation of the Local Macrophage Inflammasome Is Required for Virulence of Streptococcus uberis

Richard D Emes, M. F. Addis, Nathan Archer, 2020, Pathogens.