I. M. Wormstone

发表

Thapsigargin-coated intraocular lenses inhibit human lens cell growth

P. D. Davies, P. Davies, G. Duncan, 1997, Nature Medicine.

Lens cell survival after exposure to stress in the closed capsular bag.

G. Duncan, I. M. Wormstone, Lixin Wang, 2007, Investigative ophthalmology & visual science.

Growth factor restriction impedes progression of wound healing following cataract surgery: identification of VEGF as a putative therapeutic target

D. Spalton, I. M. Wormstone, M. McDonald, 2016, Scientific Reports.

Phacoemulsification versus extracapsular cataract extraction: a comparative study of cell survival and growth on the human capsular bag in vitro

P. Davies, G. Duncan, I. M. Wormstone, 1997, The British journal of ophthalmology.

Assessment of intraocular lens/capsular bag biomechanical interactions following cataract surgery in a human in vitro graded culture capsular bag model.

Niklas B Damm, I. M. Wormstone, J. A. Eldred, 2021, Experimental eye research.

An In Vitro Human Lens Capsular Bag Model Adopting a Graded Culture Regime to Assess Putative Impact of IOLs on PCO Formation.

I. M. Wormstone, Su-mei Chen, J. A. Eldred, 2019, Investigative ophthalmology & visual science.

TGFbeta isoform dependent Smad2/3 kinetics in human lens epithelial cells: a Cellomics analysis.

M. Sleeman, H. Angell, I. M. Wormstone, 2007, Experimental eye research.

MMP and TIMP expression in quiescent, dividing, and differentiating human lens cells.

D. Edwards, C. Pennington, G. Duncan, 2007, Investigative ophthalmology & visual science.

The aging human lens: structure, growth, and physiological behaviour

P. Davies, G. Duncan, I. M. Wormstone, 1997, The British journal of ophthalmology.

Serum deprivation can suppress receptor-mediated calcium signaling in pterygial-derived fibroblasts.

I. M. Wormstone, L. Qian, C. Illingworth, 2013, Investigative ophthalmology & visual science.

The ocular lens: a classic model for development, physiology and disease

M. Wride, I. M. Wormstone, I. Wormstone, 2011, Philosophical Transactions of the Royal Society B: Biological Sciences.

ADAM and ADAMTS gene expression in native and wound healing human lens epithelial cells

D. Edwards, G. Duncan, I. M. Wormstone, 2010, Molecular vision.

Arsenic trioxide initiates ER stress responses, perturbs calcium signalling and promotes apoptosis in human lens epithelial cells.

Hong Zhang, Ping Liu, G. Duncan, 2007, Experimental eye research.

Cellular FLICE-like inhibitory protein (cFLIP) critically maintains apoptotic resistance in human lens epithelial cells

Caili Hao, I. M. Wormstone, Xingjun Fan, 2021, Cell Death & Disease.

Resveratrol Inhibits Wound Healing and Lens Fibrosis: A Putative Candidate for Posterior Capsule Opacification Prevention.

Andrew J O Smith, I. M. Wormstone, J. A. Eldred, 2019, Investigative ophthalmology & visual science.

An in vitro evaluation of the Anew Zephyr open-bag IOL in the prevention of posterior capsule opacification using a human capsular bag model.

D. Spalton, I. M. Wormstone, J. A. Eldred, 2014, Investigative ophthalmology & visual science.

physiological behaviour The aging human lens: structure, growth, and

P. Davies, G. Duncan, I. M. Wormstone, 2006 .

Sigma 1 receptor stimulation protects against oxidative damage through suppression of the ER stress responses in the human lens

R. Bowater, Andrew J O Smith, I. M. Wormstone, 2012, Mechanisms of Ageing and Development.

MMP2 activity is critical for TGFβ2-induced matrix contraction--implications for fibrosis.

D. Edwards, I. M. Wormstone, J. Reddan, 2012, Investigative ophthalmology & visual science.

A focus on the human lens in vitro.

G. Duncan, I. M. Wormstone, S. Hansom, 2006, Environmental toxicology and pharmacology.

Transferrin in after-cataract and as a survival factor for lens epithelium.

M. Mcgahan, G. Duncan, I. M. Wormstone, 1998, Experimental eye research.

Lens MMP 2 Activity is Critical for TGF b 2-Induced Matrix Contraction — Implications for Fibrosis

D. Edwards, I. M. Wormstone, J. Reddan, 2012 .

Research Note: Ultraviolet Irradiation (UVB) Interrupts Calcium Cell Signaling in Lens Epithelial Cells

A. Dawson, G. Duncan, I. M. Wormstone, 1999 .

G. Duncan, I. M. Wormstone, L. Dawes, 2013, Investigative ophthalmology & visual science.

Posterior capsule opacification.

I. M. Wormstone, Lixin Wang, Christopher Liu, 2009, Experimental eye research.

Posterior capsule opacification: What's in the bag?

I. M. Wormstone, J. A. Eldred, Y. Wormstone, 2020, Progress in Retinal and Eye Research.

TGF-beta2-induced matrix modification and cell transdifferentiation in the human lens capsular bag.

S. Tamiya, G. Duncan, I. M. Wormstone, 2002, Investigative ophthalmology & visual science.

Spatial characteristics of receptor-induced calcium signaling in human lens capsular bags.

G. Duncan, I. M. Wormstone, Lixin Wang, 2004, Investigative ophthalmology & visual science.

Calcium cell signalling and cataract: Role of the endoplasmic reticulum

G. Duncan, I. M. Wormstone, I. Wormstone, 1999, Eye.

Induction of matrix metalloproteinases 2 and 9 following stress to the lens.

S. Tamiya, G. Duncan, I. M. Wormstone, 2000, Experimental eye research.

PARP-1 inhibition influences the oxidative stress response of the human lens

R. Bowater, Andrew J O Smith, I. M. Wormstone, 2016, Redox biology.

Experimental models for posterior capsule opacification research.

I. M. Wormstone, J. A. Eldred, I. Wormstone, 2016, Experimental eye research.

TGFbeta/Smad4-dependent and -independent regulation of human lens epithelial cells.

M. Sleeman, I. M. Wormstone, J. Reddan, 2009, Investigative ophthalmology & visual science.

TGF beta-induced contraction is not promoted by fibronectin-fibronectin receptor interaction, or alpha SMA expression.

M. Sleeman, G. Duncan, I. M. Wormstone, 2008, Investigative ophthalmology & visual science.

Short-term exposure to transforming growth factor beta induces long-term fibrotic responses.

G. Duncan, I. M. Wormstone, I. Anderson, 2006, Experimental eye research.

Regional differences in store-operated Ca2+ entry in the epithelium of the intact human lens.

G. Duncan, I. M. Wormstone, C. Illingworth, 2009, Investigative ophthalmology & visual science.

Regional differences in tyrosine kinase receptor signaling components determine differential growth patterns in the human lens.

S. Tamiya, G. Duncan, I. M. Wormstone, 2004, Investigative ophthalmology & visual science.

Pterygial derived fibroblasts express functionally active histamine and epidermal growth factor receptors.

R. Maini, P. Davies, I. M. Wormstone, 2002, Experimental eye research.

The lens as a model for fibrotic disease

I. M. Wormstone, J. A. Eldred, L. Dawes, 2011, Philosophical Transactions of the Royal Society B: Biological Sciences.

TGF / Smad 4-Dependent and-Independent Regulation of Human Lens Epithelial Cells

M. Sleeman, I. M. Wormstone, J. Reddan, 2009 .

Posterior capsule opacification: a cell biological perspective.

I. M. Wormstone, I. Wormstone, 2002, Experimental eye research.

Sulforaphane can protect lens cells against oxidative stress: implications for cataract prevention.

R. Bowater, Y. Bao, Hanruo Liu, 2013, Investigative ophthalmology & visual science.

Fibrotic Modifications of the Lens Epithelium

I. M. Wormstone, J. A. Eldred, L. J. Dawes, 2014 .

The human capsular bag model of posterior capsule opacification

I. M. Wormstone, I. Wormstone, I. Michael Wormstone, 2019, Eye.

Aspirin Inhibits TGFβ2-Induced Epithelial to Mesenchymal Transition of Lens Epithelial Cells: Selective acetylation of K56 and K122 in histone H3.

J. Galligan, R. Nagaraj, J. Brzezinski, 2019, The Biochemical journal.

GSH Levels Serve As a Biological Redox Switch Regulating Sulforaphane-Induced Cell Fate in Human Lens Cells

R. Bowater, S. Saha, I. M. Wormstone, 2021, Investigative ophthalmology & visual science.

Development and Validation of a Deep Learning System to Detect Glaucomatous Optic Neuropathy Using Fundus Photographs.

Robert N Weinreb, Tien Yin Wong, Mai Xu, 2019, JAMA ophthalmology.

Chemopreventive Activities of Sulforaphane and Its Metabolites in Human Hepatoma HepG2 Cells

R. Bowater, P. Liu, Y. Bao, 2018, Nutrients.

Improving the drug development process by reducing the impact of adverse events: the case of cataracts considered.

Andrew F. Smith, I. M. Wormstone, A. Klotz, 2016, Drug discovery today.

Growth factor receptor signalling in human lens cells: role of the calcium store.

G. Duncan, I. M. Wormstone, Lixin Wang, 2005, Experimental eye research.

Ku80 Counters Oxidative Stress-Induced DNA Damage and Cataract Formation in the Human Lens.

R. Bowater, I. M. Wormstone, Andrew J. O. Smith, 2015, Investigative ophthalmology & visual science.

AGEs in human lens capsule promote the TGFβ2‐mediated EMT of lens epithelial cells: implications for age‐associated fibrosis

Dawn G. Smith, S. Howell, R. Nagaraj, 2016, Aging cell.

A study of human lens cell growth in vitro. A model for posterior capsule opacification.

G Duncan, P. Davies, G. Duncan, 1996, Investigative ophthalmology & visual science.

Human lens epithelial cell proliferation in a protein-free medium.

G. Vrensen, G. Duncan, I. M. Wormstone, 1997, Investigative ophthalmology & visual science.

Oligonucleotide microarray analysis of human lens epithelial cells: TGFbeta regulated gene expression.

I. M. Wormstone, J. Reddan, L. Dawes, 2007, Molecular vision.

FGF: an autocrine regulator of human lens cell growth independent of added stimuli.

P. Davies, S. Tamiya, K. Del Rio-Tsonis, 2001, Investigative ophthalmology & visual science.