Gevorg Grigoryan

发表

Design and designability of protein-based assemblies.

Jian Zhang, Fan Zheng, Gevorg Grigoryan, 2014, Current opinion in structural biology.

Contact prediction is hardest for the most informative contacts, but improves with the incorporation of contact potentials

Gevorg Grigoryan, Qinxin Pan, Jack Holland, 2018, PloS one.

Structure‐based design of combinatorial mutagenesis libraries

Chris Bailey-Kellogg, Gevorg Grigoryan, Deeptak Verma, 2015, Protein science : a publication of the Protein Society.

Identifying and reducing error in cluster‐expansion approximations of protein energies

Gevorg Grigoryan, Amy E. Keating, Seungsoo Hahn, 2010, J. Comput. Chem..

Probabilistic surfaces: point based primitives to show surface uncertainty

Penny Rheingans, Gevorg Grigoryan, 2002, IEEE Visualization, 2002. VIS 2002..

Making Picky Proteins: Computational Design of Interaction Specificity

Gevorg Grigoryan, 2012 .

Cluster expansion models for flexible‐backbone protein energetics

Gevorg Grigoryan, Amy E. Keating, Seungsoo Hahn, 2009, J. Comput. Chem..

Ultra-Fast Evaluation of Protein Energies Directly from Sequence

Fei Zhou, Gevorg Grigoryan, Gerbrand Ceder, 2006, PLoS Comput. Biol..

Using Color to Understand Light Transmission

Gevorg Grigoryan, Curtis R. Menyuk, Ivan T. Lima, 2000 .

A general-purpose protein design framework based on mining sequence–structure relationships in known protein structures

Gevorg Grigoryan, Jianfu Zhou, Alexandra E Panaitiu, 2019, Proceedings of the National Academy of Sciences.

Absolute free energies of biomolecules from unperturbed ensembles

Gevorg Grigoryan, G. Grigoryan, 2013, J. Comput. Chem..

Simplifying the Design of Protein-Peptide Interaction Specificity with Sequence-Based Representations of Atomistic Models.

Fan Zheng, Gevorg Grigoryan, G. Grigoryan, 2017, Methods in molecular biology.

Tertiary structural motif sequence statistics enable facile prediction and design of peptides that bind anti-apoptotic Bfl-1 and Mcl-1

Gevorg Grigoryan, Amy E. Keating, Vincent Frappier, 2018 .

OCoM-SOCoM: Combinatorial Mutagenesis Library Design Optimally Combining Sequence and Structure Information

Chris Bailey-Kellogg, Gevorg Grigoryan, Deeptak Verma, 2016, BCB.

Structural informatics, modeling, and design with an open‐source Molecular Software Library (MSL)

Gevorg Grigoryan, Alessandro Senes, Brett T. Hannigan, 2012, J. Comput. Chem..

Point-based probabilistic surfaces to show surface uncertainty

Penny Rheingans, Gevorg Grigoryan, P. Rheingans, 2004, IEEE Transactions on Visualization and Computer Graphics.

Pareto Optimization of Combinatorial Mutagenesis Libraries

Gevorg Grigoryan, Chris Bailey-Kellogg, Deeptak Verma, 2019, IEEE/ACM Transactions on Computational Biology and Bioinformatics.

A C++ library for protein sub-structure search

Gevorg Grigoryan, Jianfu Zhou, G. Grigoryan, 2020, bioRxiv.

A general-purpose protein design framework based on mining sequence–structure relationships in known protein structures

Gevorg Grigoryan, Jianfu Zhou, Alexandra E. Panaitiu, 2018, Proceedings of the National Academy of Sciences.

Transmembrane communication: general principles and lessons from the structure and function of the M2 proton channel, K⁺ channels, and integrin receptors.

Gevorg Grigoryan, W. DeGrado, G. Grigoryan, 2011, Annual review of biochemistry.

Protein structural motifs in prediction and design.

Gevorg Grigoryan, Craig O. Mackenzie, G. Grigoryan, 2017, Current opinion in structural biology.

Sequence statistics of tertiary structural motifs reflect protein stability

Gevorg Grigoryan, G. Grigoryan, Fan Zheng, 2017, PloS one.

De novo design of a transmembrane Zn[superscript 2+]-transporting four-helix bundle

Gevorg Grigoryan, Michael Grabe, Tuo Wang, 2014 .

Tertiary alphabet for the observable protein structural universe

Gevorg Grigoryan, Craig O. Mackenzie, Jianfu Zhou, 2016, Proceedings of the National Academy of Sciences.

Tertiary structural motif sequence statistics enable facile prediction and design of peptides that bind anti-apoptotic Bfl-1 and Mcl-1

Gevorg Grigoryan, Vincent Frappier, Amy E Keating, 2018, bioRxiv.

Design of protein-interaction specificity affords selective bZIP-binding peptides

Gevorg Grigoryan, Amy E. Keating, A. Keating, 2009, Nature.

Design of a Heterospecific, Tetrameric, 21-Residue Miniprotein with Mixed α/β Structure

Gevorg Grigoryan, Amy E. Keating, Barbara Imperiali, 2005 .

Computational design and experimental characterization of peptides intended for pH-dependent membrane insertion and pore formation.

Gevorg Grigoryan, W. DeGrado, G. Grigoryan, 2015, ACS chemical biology.

Mining tertiary structural motifs for assessment of designability.

Gevorg Grigoryan, Jian Zhang, G. Grigoryan, 2013, Methods in enzymology.

Probing designability via a generalized model of helical bundle geometry.

Gevorg Grigoryan, W. DeGrado, G. Grigoryan, 2011, Journal of molecular biology.

Coarse-graining protein energetics in sequence variables.

Gevorg Grigoryan, Gerbrand Ceder, Dane Morgan, 2005, Physical review letters.

De novo design of a transmembrane Zn2+-transporting four-helix bundle

Gevorg Grigoryan, Michael Grabe, Tuo Wang, 2014, Science.

Computational design of selective peptides to discriminate between similar PDZ domains in an oncogenic pathway.

Gevorg Grigoryan, Jian Zhang, G. Grigoryan, 2015, Journal of molecular biology.

Structure-based prediction of bZIP partnering specificity.

Gevorg Grigoryan, Amy E Keating, A. Keating, 2006, Journal of molecular biology.

Tertiary structural propensities reveal fundamental sequence/structure relationships.

Gevorg Grigoryan, Jian Zhang, G. Grigoryan, 2015, Structure.

Rapid search for tertiary fragments reveals protein sequence–structure relationships

Gevorg Grigoryan, Jianfu Zhou, G. Grigoryan, 2015, Protein science : a publication of the Protein Society.

Design of a heterospecific, tetrameric, 21-residue miniprotein with mixed alpha/beta structure.

Gevorg Grigoryan, Barbara Imperiali, Amy E Keating, 2005, Structure.