Xiao-Dong Chen

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Stromal-cell-derived extracellular matrix promotes the proliferation and retains the osteogenic differentiation capacity of mesenchymal stem cells on three-dimensional scaffolds.

Jian Ling, B. Antebi, Zhongding Lu, 2015, Tissue engineering. Part C, Methods.

Biglycan Deficiency Interferes With Ovariectomy‐Induced Bone Loss

T. L. Andersen, M. Allen, M. Young, 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Use of MSCs in Antiaging Strategies

D. Dean, Xiao-Dong Chen, T. Block, 2019, A Roadmap to Non-Hematopoietic Stem Cell-based Therapeutics.

What Can We Learn From This Book?

D. Dean, Xiao-Dong Chen, T. Block, 2019, A Roadmap to Non-Hematopoietic Stem Cell-based Therapeutics.

Restoring the quantity and quality of elderly human mesenchymal stem cells for autologous cell-based therapies

D. Dean, Xiao-Dong Chen, T. Block, 2017, Stem Cell Research & Therapy.

Extracellular Matrix Proteoglycans Control the Fate of Bone Marrow Stromal Cells*

C. Stuelten, R. Iozzo, M. Young, 2005, Journal of Biological Chemistry.

Rescuing replication and osteogenesis of aged mesenchymal stem cells by exposure to a young extracellular matrix

Jian Ling, R. Jilka, Qitao Ran, 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

S. Shi, M. Young, P. Robey, 2002, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Biglycan knockout mice: New models for musculoskeletal diseases

M. Young, Y. Bi, L. Ameye, 2002, Glycoconjugate Journal.

Dissection of the sets of genes that control the behavior of biglycan-deficient pre-osteoblasts using oligonucleotide microarrays.

Tanya M. Teslovich, D. Stephan, M. Young, 2005, Bone.

The Urokinase Plasminogen Activator Receptor–Associated Protein/Endo180 Is Coexpressed with Its Interaction Partners Urokinase Plasminogen Activator Receptor and Matrix Metalloprotease-13 during Osteogenesis

B. Nielsen, C. López-Otín, H. Birkedal‐Hansen, 2001, Laboratory Investigation.

Organ-specific extracellular matrix directs trans-differentiation of mesenchymal stem cells and formation of salivary gland-like organoids in vivo

D. Dean, Yuyang Sun, Brij B. Singh, 2022, Stem cell research & therapy.

Culture on a native bone marrow-derived extracellular matrix restores the pancreatic islet basement membrane, preserves islet function, and attenuates islet immunogenicity

R. DeFronzo, D. Dean, Hanzhou Wang, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Characterization of bone marrow derived mesenchymal stem cells in suspension

L. Tang, S. Gronthos, Yan Jin, 2012, Stem Cell Research & Therapy.

Interferon regulatory factor-1 exerts inhibitory effect on neointimal formation after vascular injury.

B. Han, Xiao-Dong Chen, Zhen Li, 2009, Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih.

Extracellular Matrix Made by Bone Marrow Cells Facilitates Expansion of Marrow‐Derived Mesenchymal Progenitor Cells and Prevents Their Differentiation Into Osteoblasts

R. Jilka, S. Manolagas, Jian Q. Feng, 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Silk fibroin scaffolds promote formation of the ex vivo niche for salivary gland epithelial cell growth, matrix formation, and retention of differentiated function.

J. Ong, D. Dean, Hanzhou Wang, 2015, Tissue engineering. Part A.

Native extracellular matrix preserves mesenchymal stem cell “stemness” and differentiation potential under serum-free culture conditions

D. Dean, Qiuxia Dai, Xiao-Dong Chen, 2015, Stem Cell Research & Therapy.

Estrogens Attenuate Oxidative Stress and the Differentiation and Apoptosis of Osteoblasts by DNA-Binding-Independent Actions of the ERα

P. Roberson, M. Almeida, E. Ambrogini, 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Thy‐1 Antigen Expression by Cells in the Osteoblast Lineage

L. Neff, K. Satomura, H. Qian, 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Umbilical cord blood-derived non-hematopoietic stem cells retrieved and expanded on bone marrow-derived extracellular matrix display pluripotent characteristics

D. Dean, Zhongding Lu, Zhiliang Zhang, 2016, Stem Cell Research & Therapy.

The small leucine‐rich proteoglycan biglycan modulates BMP‐4‐induced osteoblast differentiation

M. Young, P. Robey, Pamela Gehron Robey, 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Biomimetic collagen-hydroxyapatite composite fabricated via a novel perfusion-flow mineralization technique.

Jian Ling, Xingguo Cheng, L. Gower, 2013, Tissue engineering. Part C, Methods.

The Wnt antagonist and secreted frizzled-related protein 5: implications on lipid metabolism, inflammation, and type 2 diabetes mellitus

Qing Zhu, Xiao-Dong Chen, Ling-Bin Liu, 2018, Bioscience reports.

Characterization of bone marrow derived mesenchymal stem cells in suspension

L. Tang, S. Gronthos, Yan Jin, 2012, Stem Cell Research & Therapy.

One size does not fit all: developing a cell-specific niche for in vitro study of cell behavior.

D. Dean, E. Wang, Xiao-Dong Chen, 2016, Matrix biology : journal of the International Society for Matrix Biology.

Native extracellular matrix preserves mesenchymal stem cell “stemness” and differentiation potential under serum-free culture conditions

D. Dean, Qiuxia Dai, Xiao-Dong Chen, 2015, Stem Cell Research & Therapy.

Native extracellular matrix, synthesized ex vivo by bone marrow or adipose stromal cells, faithfully directs mesenchymal stem cell differentiation

D. Dean, C. Yeh, Xiao-Dong Chen, 2020, Matrix biology plus.

Reconstitution of marrow-derived extracellular matrix ex vivo: a robust culture system for expanding large-scale highly functional human mesenchymal stem cells.

Jian Ling, R. Tuan, R. Jilka, 2010, Stem cells and development.

Bmp2 in osteoblasts of periosteum and trabecular bone links bone formation to vascularization and mesenchymal stem cells

J. Nyman, Y. Mishina, D. Rowe, 2013, Journal of Cell Science.

Extracellular matrix provides an optimal niche for the maintenance and propagation of mesenchymal stem cells.

Xiao-Dong Chen, 2010, Birth defects research. Part C, Embryo today : reviews.

One in vitro model for visceral adipose-derived fibroblasts in chronic inflammation.

Xian-hui He, T. Xia, S. Feng, 2005, Biochemical and biophysical research communications.

A crucial role of caspase-3 in osteogenic differentiation of bone marrow stromal stem cells.

R. Flavell, Xin-Hua Feng, S. Gronthos, 2004, The Journal of clinical investigation.

Assessing the role of IL-35 in colorectal cancer progression and prognosis.

Zhi-Yong Wang, Hong-mei Wang, B. Kong, 2013, International journal of clinical and experimental pathology.

Maintenance and Culture of MSCs

D. Dean, Xiao-Dong Chen, M. Marinković, 2019, A Roadmap to Non-Hematopoietic Stem Cell-based Therapeutics.

The mechanical phenotype of biglycan-deficient mice is bone- and gender-specific.

Joseph M. Wallace, Matthew R Allen, Joseph M Wallace, 2006, Bone.

Matrix-bound Cyr61/CCN1 is required to retain the properties of the bone marrow mesenchymal stem cell niche but is depleted with aging

D. Dean, S. Harris, A. Salmon, 2022, Matrix biology : journal of the International Society for Matrix Biology.

Autologous mesenchymal stem cells offer a new paradigm for salivary gland regeneration

D. Dean, Hanzhou Wang, Xiao-Dong Chen, 2023, International journal of oral science.

Restoring the quantity and quality of elderly human mesenchymal stem cells for autologous cell-based therapies

D. Dean, Xiao-Dong Chen, T. Block, 2017, Stem Cell Research & Therapy.

Olmesartan inhibits the expression of monocyte chemoattractant protein-1 and tumor necrosis factor-alpha and improves vascular remodeling after vascular injury in mouse.

Mu-sheng Lin, Xiao-Dong Chen, Zhen Li, 2004, Chinese journal of traumatology = Zhonghua chuang shang za zhi.

COL4A2 in the tissue-specific extracellular matrix plays important role on osteogenic differentiation of periodontal ligament stem cells

Hongxu Yang, D. Bai, Zuolin Jin, 2019, Theranostics.

[Role of pilose antler polypeptides on replicative senescence of rat chondrocyte].

Xiao-Dong Chen, Jian-hua Lin, 2008, Zhongguo gu shang = China journal of orthopaedics and traumatology.

Inhibitory effect of angiotensin II type 1 receptor-associated protein on vascular smooth muscle cell growth and neointimal formation.

Xiao-Dong Chen, Zhen Li, Zhong-gao Wang, 2007, Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih.

[Observation of replicative senescence of rat chondrocytes in vitro].

Jianhua Lin, Xiao-Dong Chen, Lingxiao Deng, 2007, Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery.

Umbilical cord blood-derived non-hematopoietic stem cells retrieved and expanded on bone marrow-derived extracellular matrix display pluripotent characteristics

D. Dean, Zhongding Lu, Zhiliang Zhang, 2016, Stem Cell Research & Therapy.

Autocrine Factors Produced by Mesenchymal Stem Cells in Response to Cell–Cell Contact Inhibition Have Anti-Tumor Properties

Xiao-Dong Chen, Rong Li, Jerry Chen, 2023, Cells.

Extracellular matrix provides an optimal niche for the maintenance and propagation of mesenchymal stem cells.

Xiao-Dong Chen, 2010, Birth defects research. Part C, Embryo today : reviews.