Xi Lin

Shoeb Ahmad, Wenxue Tang, Xi Lin, 2009, Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.

Connexin29 Is Highly Expressed in Cochlear Schwann Cells, and It Is Required for the Normal Development and Function of the Auditory Nerve of Mice

D. Paul, Yanping Zhang, Wenxue Tang, 2006, The Journal of Neuroscience.

Early postnatal virus inoculation into the scala media achieved extensive expression of exogenous green fluorescent protein in the inner ear and preserved auditory brainstem response thresholds

Shoeb Ahmad, Xi Lin, Q. Chang, 2013, The journal of gene medicine.

Restoration of connexin26 protein level in the cochlea completely rescues hearing in a mouse model of human connexin30-linked deafness

K. Willecke, Shoeb Ahmad, G. Söhl, 2007, Proceedings of the National Academy of Sciences.

Adaptor protein-3 complex is required for Vangl2 trafficking and planar cell polarity of the inner ear

Ping Chen, V. Faundez, Hao Wu, 2019, Molecular biology of the cell.

Functional Evaluation of GJB 2 Variants in Nonsyndromic Hearing Loss

C. Jeon, J. Bok, U. Kim, 2011 .

Gap junction-mediated intercellular biochemical coupling in cochlear supporting cells is required for normal cochlear functions.

Xi Lin, Yanping Zhang, Wenxue Tang, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Cochlear gap junctions coassembled from Cx26 and 30 show faster intercellular Ca2+ signaling than homomeric counterparts.

Yanping Zhang, Wenxue Tang, Xi Lin, 2005, American journal of physiology. Cell physiology.

Down regulated connexin26 at different postnatal stage displayed different types of cellular degeneration and formation of organ of Corti.

W. Kong, Yu Sun, Xi Lin, 2014, Biochemical and biophysical research communications.

Reduced expression of Connexin26 and its DNA promoter hypermethylation in the inner ear of mimetic aging rats induced by d-galactose.

W. Kong, Yu Sun, Xi Lin, 2014, Biochemical and biophysical research communications.

Virally-expressed connexin26 restores gap junction function in the cochlea of conditional Gjb2 knockout mice

Jianjun Wang, Xi Lin, Q. Chang, 2013, Gene Therapy.

Early developmental expression of connexin26 in the cochlea contributes to its dominate functional role in the cochlear gap junctions.

Shoeb Ahmad, Xiaoming Li, Wenxue Tang, 2012, Biochemical and biophysical research communications.

Connexin30 null and conditional connexin26 null mice display distinct pattern and time course of cellular degeneration in the cochlea

W. Kong, Wenxue Tang, Xi Lin, 2009, The Journal of comparative neurology.

Genetics of Hearing and Deafness

X. Liu, S. Angeli, Xi Lin, 2012, Anatomical record.

Establishment of a Knock-In Mouse Model with the SLC26A4 c.919-2A>G Mutation and Characterization of Its Pathology

Xi Lin, Chen-Chi Wu, Jau-Min Wong, 2011, PloS one.

Virally mediated Kcnq1 gene replacement therapy in the immature scala media restores hearing in a mouse model of human Jervell and Lange-Nielsen deafness syndrome

Jianjun Wang, Xi Lin, Q. Chang, 2015, EMBO molecular medicine.

A Missense Mutation in POU4F3 Causes Midfrequency Hearing Loss in a Chinese ADNSHL Family

Xue Gao, Guo-jian Wang, Yongyi Yuan, 2018, BioMed research international.

Expression of Islet1 marks the sensory and neuronal lineages in the mammalian inner ear

Ping Chen, N. Segil, L. Pan, 2004, The Journal of comparative neurology.

Deoxygedunin, a Natural Product with Potent Neurotrophic Activity in Mice

Xi Lin, Kerry J. Ressler, Chi Bun Chan, 2010, PloS one.

Gene therapy for genetic mutations affecting non-sensory cells in the cochlea

Xi Lin, Xuewen Wu, Li Zhang, 2019, Hearing Research.

Applications of targeted gene capture and next-generation sequencing technologies in studies of human deafness and other genetic disabilities

Xi Lin, Jason Zhu, Shoeb Ahmad, 2012, Hearing Research.

Cilia distribution and polarity in the epithelial lining of the mouse middle ear cavity

Ping Chen, Dongdong Ren, F. Chi, 2017, Scientific Reports.

Analysis of connexin subunits required for the survival of vestibular hair cells

Ping Chen, K. Willecke, R. Salvi, 2007, The Journal of comparative neurology.

Comprehensive genetic testing of Chinese SNHL patients and variants interpretation using ACMG guidelines and ethnically matched normal controls

Jianguo Zhang, Hankui Liu, Xue Gao, 2019, European Journal of Human Genetics.

Targeted gene capture and massively parallel sequencing identify TMC1 as the causative gene in a six‐generation Chinese family with autosomal dominant hearing loss

Xue Gao, Guo-jian Wang, Yongyi Yuan, 2015, American journal of medical genetics. Part A.

Combined examination of sequence and copy number variations in human deafness genes improves diagnosis for cases of genetic deafness

Jianjun Wang, Xi Lin, Huawei Li, 2014, BMC Ear, Nose and Throat Disorders.

De novo mutation in ATP6V1B2 impairs lysosome acidification and causes dominant deafness-onychodystrophy syndrome

Weiwei Guo, Ping Chen, Hui Jiang, 2014, Cell Research.

Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway

Xi Lin, Ping Chen, Ping Chen, 2005, Nature Genetics.

A Novel Mechanism for Connexin 26 Mutation Linked Deafness: Cell Death Caused by Leaky Gap Junction Hemichannels

Xi Lin, Shoeb Ahmad, Shoeb Ahmad, 2006, The Laryngoscope.

Changes in gap junctional connexin isoforms during prostate cancer progression

Xi Lin, M. Edlund, Tina K. Lung, 2006, The Prostate.

Structure and Function of Cochlear Gap Junctions and Implications for the Translation of Cochlear Gene Therapies

Xi Lin, Xuewen Wu, Wenjuan Zhang, 2019, Front. Cell. Neurosci..

Characterization of ATPase Activity of P2RX2 Cation Channel

X. Liu, Yanbin Zhang, F. Yuan, 2016, Front. Physiol..

Atoh1 Directs the Formation of Sensory Mosaics and Induces Cell Proliferation in the Postnatal Mammalian Cochlea In Vivo

Michael C. Kelly, Xi Lin, Q. Chang, 2012, The Journal of Neuroscience.

Functional Evaluation of GJB2 Variants in Nonsyndromic Hearing Loss

Xi Lin, Hong-Joon Park, Un-Kyung Kim, 2011, Molecular medicine.

Phenotypic Heterogeneity in a DFNA20/26 family segregating a novel ACTG1 mutation

Xi Lin, Xue Gao, Yongyi Yuan, 2016, BMC Genetics.

Phenotypic Heterogeneity in a DFNA 20 / 26 family segregating a novel ACTG 1 mutation

Xue Gao, Guo-jian Wang, Yongyi Yuan, 2022 .

Different functional consequences of two missense mutations in the GJB2 gene associated with non‐syndromic hearing loss

Xi Lin, Sang Heun Lee, Hong-Joon Park, 2009, Human mutation.

Novel Compound Heterozygous Mutations in MYO7A Associated with Usher Syndrome 1 in a Chinese Family

Hui Zhao, Xue Gao, Guo-jian Wang, 2014, PloS one.

7,8,3'-Trihydroxyflavone, a potent small molecule TrkB receptor agonist, protects spiral ganglion neurons from degeneration both in vitro and in vivo.

K. Ye, Xia Liu, S. Gong, 2012, Biochemical and biophysical research communications.

Spatial and Age-Dependent Hair Cell Generation in the Postnatal Mammalian Utricle

Michael C. Kelly, F. Chi, Zhen Gao, 2016, Molecular Neurobiology.

Correction: Novel Compound Heterozygous Mutations in MYO7A Associated with Usher Syndrome 1 in a Chinese Family

Hui Zhao, Xue Gao, Guo-jian Wang, 2015, PloS one.

Timed conditional null of connexin26 in mice reveals temporary requirements of connexin26 in key cochlear developmental events before the onset of hearing

Wenxue Tang, Xi Lin, Q. Chang, 2015, Neurobiology of Disease.

Localization of Glucose Transporter 10 to Hair Cells' Cuticular Plate in the Mouse Inner Ear

Wenxue Tang, Xi Lin, Bei Chen, 2018, BioMed Research International.

Diverse deafness mechanisms of connexin mutations revealed by studies using in vitro approaches and mouse models

Shoeb Ahmad, Wenxue Tang, Xi Lin, 2009, Brain Research.