C. de Jonghe

发表

The Glu318Gly substitution in presenilin 1 is not causally related to Alzheimer disease.

A. Hofman, H. Vanderstichele, C. V. van Duijn, 1999, American journal of human genetics.

Aberrant splicing in the presenilin-1 intron 4 mutation causes presenile Alzheimer's disease by increased Abeta42 secretion.

J. Hardy, P. S. St George-Hyslop, C. Morris, 1999, Human molecular genetics.

Phosphatidylinositol 3‐kinase activity is required for the expression of glial fibrillary acidic protein upon cAMP‐dependent induction of differentiation in rat C6 glioma

C. Broeckhoven, C. van Broeckhoven, D. Roymans, 2001, Journal of neurochemistry.

Nonfibrillar diffuse amyloid deposition due to a gamma(42)-secretase site mutation points to an essential role for N-truncated A beta(42) in Alzheimer's disease.

H. Vanderstichele, B. Strooper, B. de Strooper, 2000, Human molecular genetics.

Processing of presenilin 1 in brains of patients with Alzheimer's disease and controls

C. van Broeckhoven, L. Hendriks, S. Sisodia, 1997, Neuroreport.

Pathogenic APP mutations near the gamma-secretase cleavage site differentially affect Abeta secretion and APP C-terminal fragment stability.

B. de Strooper, C. van Broeckhoven, S. Serneels, 2001, Human molecular genetics.

Flemish and Dutch mutations in amyloid beta precursor protein have different effects on amyloid beta secretion.

C. van Broeckhoven, L. Hendriks, C. Eckman, 1998, Neurobiology of disease.

Molecular genetic analysis of familial early-onset Alzheimer's disease linked to chromosome 14q24.3.

M. Cruts, J. Theuns, H. Backhovens, 1995, Human molecular genetics.

Nucleoside diphosphate kinase beta (Nm23-R1/NDPKbeta) is associated with intermediate filaments and becomes upregulated upon cAMP-induced differentiation of rat C6 glioma.

C. van Broeckhoven, I. Lascu, D. Roymans, 2000, Experimental cell research.

Identification of a Drosophila presenilin homologue: evidence of alternatively spliced forms.

C. van Broeckhoven, G. Marfany, L. Hendriks, 1998, Journal of neurogenetics.

Pathology of early-onset Alzheimer's disease cases bearing the Thr113-114ins presenilin-1 mutation.

C. Morris, D. Rubinsztein, M. Cruts, 2000, Brain : a journal of neurology.

Identification of caspases that cleave presenilin‐1 and presenilin‐2

Wim Declercq, Peter Vandenabeele, P. Vandenabeele, 1999, FEBS letters.

Identification of the tumor metastasis suppressor Nm23-H1/Nm23-R1 as a constituent of the centrosome.

C. Broeckhoven, C. van Broeckhoven, D. Roymans, 2001, Experimental cell research.

Cerebral amyloid angiopathy is a pathogenic lesion in Alzheimer's disease due to a novel presenilin 1 mutation.

M. Cruts, J. Martín, P. Cras, 2001, Brain : a journal of neurology.

Presentation of amyloidosis in carriers of the codon 692 mutation in the amyloid precursor protein gene (APP692).

A. Hofman, C. Broeckhoven, C. V. van Duijn, 2000, Brain : a journal of neurology.

Hereditary cerebral hemorrhage with amyloidosis Dutch type (AbetaPP 693): decreased plasma amyloid-beta 42 concentration.

C. van Broeckhoven, R. Roos, S. Younkin, 2003, Neurobiology of disease.