S. Giorgetti

发表

In situ characterization of protein aggregates in human tissues affected by light chain amyloidosis: a FTIR microspectroscopy study

S. Doglia, A. Natalello, G. Merlini, 2016, Scientific Reports.

A Partially Structured Species of β2-Microglobulin Is Significantly Populated under Physiological Conditions and Involved in Fibrillogenesis*

C. Dobson, F. Chiti, G. Ramponi, 2001, The Journal of Biological Chemistry.

Effects of the known pathogenic mutations on the aggregation pathway of the amyloidogenic peptide of apolipoprotein A-I.

C. Dobson, Paul Robustelli, S. Doglia, 2011, Journal of molecular biology.

Clinical ApoA‐IV amyloid is associated with fibrillogenic signal sequence

A. Corazza, P. Hawkins, P. Westermark, 2021, The Journal of pathology.

Detection of two partially structured species in the folding process of the amyloidogenic protein beta 2-microglobulin.

C. Dobson, F. Chiti, N. Taddei, 2001, Journal of molecular biology.

Molecular insights into cell toxicity of a novel familial amyloidogenic variant of b 2-microglobulin

M. Bucciantini, M. Stefani, D. Nosi, 2016 .

Benefit of doxycycline treatment on articular disability caused by dialysis related amyloidosis

M. Gobbi, M. Salmona, G. Merlini, 2013, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

S-Homocysteinylation effects on transthyretin: Worsening of cardiomyopathy onset.

M. Bucciantini, M. Stefani, P. Paoli, 2020, Biochimica et biophysica acta. General subjects.

Recombinant amyloidogenic domain of ApoA-I: analysis of its fibrillogenic potential.

C. Dobson, R. Piccoli, A. Arciello, 2006, Biochemical and Biophysical Research Communications - BBRC.

Pharmaceutical strategies against amyloidosis: old and new drugs in targeting a "protein misfolding disease".

G. Merlini, S. Grossi, V. Bellotti, 2004, Current medicinal chemistry.

The intracellular quality control system down-regulates the secretion of amyloidogenic apolipoprotein A-I variants: a possible impact on the natural history of the disease.

G. Chiesa, G. Merlini, C. Parolini, 2011, Biochimica et biophysica acta.

The interaction of β2-microglobulin with gold nanoparticles: impact of coating, charge and size.

F. Fogolari, G. Esposito, P. Posocco, 2018, Journal of materials chemistry. B.

Oleuropein aglycone: A polyphenol with different targets against amyloid toxicity.

M. Bucciantini, M. Stefani, S. Raimondi, 2018, Biochimica et biophysica acta. General subjects.

DE loop mutations affect beta2-microglobulin stability and amyloid aggregation.

M. Bolognesi, S. Raimondi, V. Bellotti, 2008, Biochemical and biophysical research communications.

Heparin Strongly Enhances the Formation of β2-Microglobulin Amyloid Fibrils in the Presence of Type I Collagen*

S. De Stefano, A. Gliozzi, O. Cavalleri, 2008, Journal of Biological Chemistry.

The workings of the amyloid diseases

G. Merlini, L. Obici, G. Palladini, 2007, Annals of medicine.

2‐DE and MALDI‐TOF‐MS for a comparative analysis of proteins expressed in different cellular models of amyotrophic lateral sclerosis

C. Cereda, M. Carrì, P. Iadarola, 2007, Electrophoresis.

Monitoring the Interaction between beta(2)-Microglobulin and the Molecular Chaperone alpha B-crystallin by NMR and Mass Spectrometry alpha B-CRYSTALLIN DISSOCIATES beta(2)-MICROGLOBULIN OLIGOMERS

Bellotti, J. Carver, F. Fogolari, 2013 .

Amyloid damage to islet β-cells in type 2 diabetes: hypoxia or pseudo-hypoxia?

A. Vanoli, M. Paulli, G. Taylor, 2019, bioRxiv.

Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis

C. Robinson, L. Serpell, G. Taylor, 2014, Proceedings of the National Academy of Sciences.

Misidentification of transthyretin and immunoglobulin variants by proteomics due to methyl lysine formation in formalin-fixed paraffin-embedded amyloid tissue

G. Taylor, P. Mauri, A. De Palma, 2017, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

Co-fibrillogenesis of Wild-type and D76N β2-Microglobulin

S. Doglia, A. Natalello, S. Raimondi, 2016, The Journal of Biological Chemistry.

Characterization of immunoglobulin variable regions of two human pathogenic monoclonal cryocrystalglobulins.

E. Ascari, A. Mattevi, G. Merlini, 2008, Molecular immunology.

Solution structure of beta(2)-microglobulin and insights into fibrillogenesis.

F. Fogolari, A. Corazza, G. Esposito, 2005, Biochimica et biophysica acta.

A FTIR microspectroscopy study of the structural and biochemical perturbations induced by natively folded and aggregated transthyretin in HL-1 cardiomyocytes

S. Doglia, M. Bucciantini, M. Stefani, 2018, Scientific Reports.

Amyloid persistence in decellularized liver: biochemical and histopathological characterization

Andrew R. Hall, G. Taylor, P. Hawkins, 2015, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

An Analysis of Ultrasound Stimulation Effects on C. Elegans Organisms Motility

G. Matrone, S. Raimondi, S. Giorgetti, 2022, 2022 IEEE International Ultrasonics Symposium (IUS).

Mechano-enzymatic cleavage and TTR amyloidogenesis

C. Robinson, G. Taylor, J. Benesch, 2017 .

A novel mechano-enzymatic cleavage mechanism underlies transthyretin amyloidogenesis

C. Robinson, G. Taylor, J. Benesch, 2015, EMBO molecular medicine.

Reduction of conformational mobility and aggregation in W60G β2‐microglobulin: assessment by 15N NMR relaxation

F. Fogolari, A. Corazza, G. Esposito, 2013, Magnetic resonance in chemistry : MRC.

Topologically non-trivial metal-organic assemblies inhibit β2-microglobulin amyloidogenesis

F. Fogolari, G. Palmisano, G. Esposito, 2021, Cell Reports Physical Science.

Amyloid Formation by Globular Proteins: The Need to Narrow the Gap Between in Vitro and in Vivo Mechanisms

A. Corazza, S. Raimondi, L. Obici, 2022, Frontiers in Molecular Biosciences.

Exploring exchange processes in proteins by paramagnetic perturbation of NMR spectra.

H. Molinari, F. Fogolari, G. Esposito, 2020, Physical chemistry chemical physics : PCCP.

Mass Spectrometry : B-crystallin by NMR and α Chaperone-Microglobulin and the Molecular 2 β Monitoring the Interaction between Molecular Biophysics :

A. Heck, V. Alverdi, J. Carver, 2013 .

Folding and fibrillogenesis: clues from beta2-microglobulin.

F. Fogolari, A. Corazza, G. Esposito, 2010, Journal of molecular biology.

De-immunized and Functional Therapeutic (DeFT) versions of a long lasting recombinant alpha interferon for antiviral therapy.

A. D. De Groot, M. Etcheverrigaray, W. Martin, 2017, Clinical immunology.

A FTIR microspectroscopy study of the structural and biochemical perturbations induced by natively folded and aggregated transthyretin in HL-1 cardiomyocytes

S. Doglia, M. Bucciantini, M. Stefani, 2018, Scientific Reports.

Amyloidogenic the Trojan Horse for Secretion of Class I Major Histocompatibility Complex , Protein Structure and Folding :

M. Bolognesi, R. Grandori, G. Esposito, 2014 .

The effects of an ideal beta-turn on beta-2 microglobulin fold stability.

M. Bolognesi, R. Grandori, S. Raimondi, 2011, Journal of biochemistry.

Hereditary systemic amyloidosis due to Asp76Asn variant β2-microglobulin.

M. Bolognesi, C. Lacroix, P. Lozeron, 2012, The New England journal of medicine.

The solution structure of human β2‐microglobulin reveals the prodromes of its amyloid transition

A. Corazza, G. Esposito, P. Viglino, 2002, Protein science : a publication of the Protein Society.

Collagen Plays an Active Role in the Aggregation of β2-Microglobulin under Physiopathological Conditions of Dialysis-related Amyloidosis*

S. De Stefano, A. Gliozzi, R. Rolandi, 2006, Journal of Biological Chemistry.

β2‐Microglobulin isoforms display an heterogeneous affinity for type I collagen

Alessandra Corazza, Gennaro Esposito, Paolo Viglino, 2005, Protein science : a publication of the Protein Society.

Structure, Folding Dynamics, and Amyloidogenesis of D76N β2-Microglobulin

R. Rolandi, F. Chiti, G. Taylor, 2013, The Journal of Biological Chemistry.

Properties of Some Variants of Human β2-Microglobulin and Amyloidogenesis*

A. Corazza, G. Esposito, P. Viglino, 2004, Journal of Biological Chemistry.

Decoding the Structural Bases of D76N ß2-Microglobulin High Amyloidogenicity through Crystallography and Asn-Scan Mutagenesis

M. Bolognesi, A. Barbiroli, S. Ricagno, 2015, PloS one.

Fibrillar vs crystalline full-length beta-2-microglobulin studied by high-resolution solid-state NMR spectroscopy.

M. Bolognesi, L. Emsley, G. Pintacuda, 2010, Journal of the American Chemical Society.

Capillary electrophoresis analysis of different variants of the amyloidogenic protein β2‐microglobulin as a simple tool for misfolding and stability studies

E. Lorenzi, R. Colombo, S. Raimondi, 2015, Electrophoresis.

Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic β2-Microglobulin*

M. Bolognesi, R. Grandori, G. Esposito, 2013, The Journal of Biological Chemistry.

The controlling roles of Trp60 and Trp95 in beta2-microglobulin function, folding and amyloid aggregation properties.

M. Bolognesi, F. Fogolari, A. Corazza, 2008, Journal of molecular biology.

Plasminogen activation triggers transthyretin amyloidogenesis in vitro

G. Taylor, A. Corazza, M. Pepys, 2018, The Journal of Biological Chemistry.

Hepatitis C virus-associated cryoglobulinaemicglomerulonephritis with delayed appearance ofmonoclonal cryoglobulinaemia.

A. Salvadeo, A. Cerino, V. Piazza, 2001, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Development of highly stable and de-immunized versions of recombinant alpha interferon: Promising candidates for the treatment of chronic and emerging viral diseases

A. D. De Groot, M. Etcheverrigaray, M. Oggero, 2021, Clinical Immunology.

C. elegans expressing D76N β2-microglobulin: a model for in vivo screening of drug candidates targeting amyloidosis

D. Sattelle, D. Lomas, F. A. Aprile, 2019, Scientific Reports.

Crtap and p3h1 knock out zebrafish support defective collagen chaperoning as the cause of their osteogenesis imperfecta phenotype.

R. Gioia, P. Witten, B. Busse, 2020, Matrix biology : journal of the International Society for Matrix Biology.

Effects of a vitamin E-modified dialyzer (Excebrane) on beta-2-microglobulin structure and removal.

D. Brancaccio, M. Gallieni, V. Bellotti, 1999, Contributions to nephrology.

Structure, function and amyloidogenic propensity of apolipoprotein A-I

Guido Franceschini, Giampaolo Merlini, Monica Stoppini, 2006, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

Liver biopsy discloses a new apolipoprotein A-I hereditary amyloidosis in several unrelated Italian families.

E. Arbustini, F. Scolari, G. Merlini, 2004, Gastroenterology.

Conformational Switching and Fibrillogenesis in the Amyloidogenic Fragment of Apolipoprotein A-I*

J. Torres, M. Sunde, E. Monzani, 2003, The Journal of Biological Chemistry.

Amyloid fibrils derived from the apolipoprotein A1 Leu174Ser variant contain elements of ordered helical structure

M. Sunde, G. Esposito, P. Viglino, 2001, Protein science : a publication of the Protein Society.

Single point mutations induce a switch in the molecular mechanism of the aggregation of the Alzheimer's disease associated Aβ42 peptide.

C. Dobson, A. Natalello, T. Knowles, 2014, ACS chemical biology.

Targeting Amyloid Aggregation: An Overview of Strategies and Mechanisms

F. A. Aprile, P. Tortora, C. Greco, 2018, International journal of molecular sciences.

Molecular insights into cell toxicity of a novel familial amyloidogenic variant of β2‐microglobulin

M. Bucciantini, M. Stefani, D. Nosi, 2016, Journal of cellular and molecular medicine.

Calcium Binds to Transthyretin with Low Affinity

A. Corazza, V. Bellotti, W. Mandaliti, 2022, Biomolecules.

Enhanced toxicity of silver nanoparticles in transgenic Caenorhabditis elegans expressing amyloidogenic proteins

S. Ramat, T. Coccini, S. Raimondi, 2015, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

Increasing the accuracy of proteomic typing by decellularisation of amyloid tissue biopsies

G. Taylor, M. Pepys, P. Hawkins, 2017, Journal of proteomics.

Clinical, radiological, and biochemical features of a bilateral buttock amyloidoma emerging after 27 years of hemodialysis

M. Mosconi, G. Esposito, G. Merlini, 2009, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

Interference of citrate-stabilized gold nanoparticles with β2-microglobulin oligomeric association.

P. Naumov, F. Fogolari, A. Corazza, 2018, Chemical communications.

Enhanced molecular chaperone activity of the small heat-shock protein alphaB-cystallin following covalent immobilization onto a solid-phase support.

H. Griesser, J. Shapter, J. Carver, 2011, Biopolymers.

Capillary electrophoresis investigation of a partially unfolded conformation of β2‐microglobulin

E. Lorenzi, G. Massolini, F. Chiti, 2002, Electrophoresis.

Lysine 58‐cleaved β2‐microglobulin is not detectable by 2D electrophoresis in ex vivo amyloid fibrils of two patients affected by dialysis‐related amyloidosis

G. Esposito, G. Tennent, M. Monti, 2006, Protein science : a publication of the Protein Society.

Variants of β2‐microglobulin cleaved at lysine‐58 retain the main conformational features of the native protein but are more conformationally heterogeneous and unstable at physiological temperature

D. B. Corlin, N. Heegaard, A. Corazza, 2006, The FEBS journal.

Topological investigation of amyloid fibrils obtained from β2‐microglobulin

M. Monti, P. Pucci, A. Amoresano, 2002, Protein science : a publication of the Protein Society.

Dynamic of β2‐Microglobulin Fibril Formation and Reabsorption: The Role of Proteolysis

D. Brancaccio, M. Gallieni, V. Bellotti, 2001, Seminars in dialysis.

b2MICROGLOBULIN AND AMYLOIDOSIS IN CHRONIC DIALYSIS PATIENTS Dynamic of b2-Microglobulin Fibril Formation and Reabsorption: The Role of Proteolysis

D. Brancaccio, M. Gallieni, V. Bellotti, 2001 .

Sulfonated molecules that bind a partially structured species of β2‐microglobulin also influence refolding and fibrillogenesis

M. Quaglia, R. Colombo, S. Raimondi, 2008, Electrophoresis.

Search of ligands for the amyloidogenic protein β2‐microglobulin by capillary electrophoresis and other techniques

Stefania Sabella, Raffaella Colombo, Milena Quaglia, 2005, Electrophoresis.

Human beta-2 microglobulin W60V mutant structure: Implications for stability and amyloid aggregation.

M. Bolognesi, S. Raimondi, V. Bellotti, 2009, Biochemical and biophysical research communications.

Short-Chain Alkanethiol Coating for Small-Size Gold Nanoparticles Supporting Protein Stability

F. Fogolari, A. Corazza, G. Esposito, 2017 .

Effect of Tetracyclines on the Dynamics of Formation and Destructuration of β2-Microglobulin Amyloid Fibrils*♦

A. Gliozzi, M. Bucciantini, M. Stefani, 2010, The Journal of Biological Chemistry.

C. elegans Expressing Human β2-Microglobulin: A Novel Model for Studying the Relationship between the Molecular Assembly and the Toxic Phenotype

M. Salmona, L. Diomede, I. Zorzoli, 2012, PloS one.

Solution structure of β2-microglobulin and insights into fibrillogenesis

F. Fogolari, A. Corazza, G. Esposito, 2005 .

Insights into a Protein-Nanoparticle System by Paramagnetic Perturbation NMR Spectroscopy

F. Fogolari, G. Esposito, S. Giorgetti, 2020, Molecules.

A specific nanobody prevents amyloidogenesis of D76N β2-microglobulin in vitro and modifies its tissue distribution in vivo

C. Robinson, M. Bucciantini, M. Stefani, 2017, Scientific Reports.

beta2-microglobulin H31Y variant 3D structure highlights the protein natural propensity towards intermolecular aggregation.

M. Bolognesi, C. Rosano, A. Corazza, 2004, Journal of molecular biology.

Structural and Folding Dynamic Properties of the T70N Variant of Human Lysozyme*

F. Chiti, A. Corazza, G. Esposito, 2003, Journal of Biological Chemistry.

Title Structure , Folding Dynamics , and Amyloidogenesis of D 76 N β 2-Microglobulin : ROLES OF SHEAR FLOW , HYDROPHOBIC SURFACES

R. Rolandi, F. Chiti, G. Taylor, 2022 .

Purification and characterization of soluble Cichorium intybusVar. silvestre lipoxygenase.

M. Daglia, A. Papetti, S. Giorgetti, 2005, Journal of Agricultural and Food Chemistry.

Detection of fragments of β2-microglobulin in amyloid fibrils

D. Brancaccio, V. Bellotti, S. Giorgetti, 2000 .

Citrate-stabilized gold nanoparticles hinder fibrillogenesis of a pathological variant of β2-microglobulin.

F. Fogolari, G. Palmisano, A. Corazza, 2017, Nanoscale.

beta2-Microglobulin is potentially neurotoxic, but the blood brain barrier is likely to protect the brain from its toxicity.

M. Bucciantini, M. Stefani, S. Raimondi, 2008, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Atomic structure of a nanobody-trapped domain-swapped dimer of an amyloidogenic β2-microglobulin variant

L. Wyns, E. Pardon, J. Steyaert, 2011, Proceedings of the National Academy of Sciences of the United States of America.

Biochemical and Electrophysiological Modification of Amyloid Transthyretin on Cardiomyocytes.

M. Bucciantini, M. Stefani, D. Nosi, 2016, Biophysical journal.

Fibrillogenesis of human β2‐microglobulin in three‐dimensional silicon microstructures

G. Mazzini, S. Merlo, L. Strambini, 2012, Journal of biophotonics.

Comparative study of the stabilities of synthetic in vitro and natural ex vivo transthyretin amyloid fibrils

G. Taylor, A. Corazza, M. Pepys, 2020, The Journal of Biological Chemistry.

Proteomics in protein misfolding diseases

G. Merlini, R. Moratti, L. Obici, 2009, Clinical chemistry and laboratory medicine.

Proteomics of β2-microglobulin amyloid fibrils

M. Monti, P. Pucci, G. Merlini, 2005 .

Screening of fibrillogenesis inhibitors of β2-microglobulin: integrated strategies by mass spectrometry capillary electrophoresis and in silico simulations.

G. Aldini, G. Vistoli, L. Regazzoni, 2011, Analytica Chimica Acta.

Native-unlike Long-lived Intermediates along the Folding Pathway of the Amyloidogenic Protein β2-Microglobulin Revealed by Real-time Two-dimensional NMR*

P. Schanda, L. Frydman, B. Brutscher, 2009, The Journal of Biological Chemistry.

Limited proteolysis in the investigation of beta2-microglobulin amyloidogenic and fibrillar states.

M. Monti, P. Pucci, A. Amoresano, 2005, Biochimica et biophysica acta.

Amyposomes, a nanotechnological chaperone with anti-amyloidogenic activity

M. Masserini, L. Rizzi, F. Re, 2023, Annals of medicine.

Proteomics of beta2-microglobulin amyloid fibrils.

M. Monti, P. Pucci, G. Merlini, 2005, Biochimica et biophysica acta.

Equilibrium unfolding thermodynamics of beta2-microglobulin analyzed through native-state H/D exchange.

F. Fogolari, A. Corazza, G. Esposito, 2009, Biophysical journal.

A quantitative and qualitative method for direct 2‐DE analysis of murine cartilage

A. Forlino, G. Cetta, A. Rossi, 2007, Proteomics.

Inhibition of the mechano-enzymatic amyloidogenesis of transthyretin: role of ligand affinity, binding cooperativity and occupancy of the inner channel

G. Taylor, A. Corazza, M. Pepys, 2017, Scientific Reports.

D‐strand perturbation and amyloid propensity in beta‐2 microglobulin

M. Bolognesi, R. Grandori, S. Raimondi, 2011, The FEBS journal.

Stabilization of amyloidogenic β 2 m by MHCI assembly 1 Class I Major Histocomapatibility Complex : the Trojan horse for secretion of amyloidogenic β 2-microglobulin

M. Bolognesi, R. Grandori, G. Esposito, 2013 .