Lake N Paul

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The Structure of the Catalytic Domain of a Plant Cellulose Synthase and Its Assembly into Dimers[C][W][OPEN]

Daisuke Kihara, Lee Makowski, Catherine Rayon, 2014, Plant Cell.

Dynamics of an Active-Site Flap Contributes to Catalysis in a JAMM Family Metallo Deubiquitinase.

Julian E. Fuchs, J. A. Ronau, C. Das, 2015, Biochemistry.

Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product

E. Strieter, C. Das, R. Guenette, 2014, Biochemistry.

Mechanism of recruitment and activation of the endosome-associated deubiquitinase AMSH.

C. Das, Lake N Paul, C. Davies, 2013, Biochemistry.

Structural basis of substrate recognition by a bacterial deubiquitinase important for dynamics of phagosome ubiquitination

C. Das, Yunhao Tan, M. Sheedlo, 2015, Proceedings of the National Academy of Sciences.

Antibacterial activity and mechanism of action of auranofin against multi-drug resistant bacterial pathogens

M. Seleem, Tiago J. P. Sobreira, Haroon Mohammad, 2016, Scientific Reports.

Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase

Chun-Liang Chen, C. Stauffacher, Lake N. Paul, 2020, Nature Communications.

Exploring simvastatin, an antihyperlipidemic drug, as a potential topical antibacterial agent

M. Seleem, Tiago J. P. Sobreira, Haroon Mohammad, 2015, Scientific Reports.

Digestion, Purification, and Enrichment of Protein Samples for Mass Spectrometry

E. Nakayasu, Lake N. Paul, Lake N Paul, 2015, Current protocols in chemical biology.

Specificity of HCPTP variants toward EphA2 tyrosines by quantitative selected reaction monitoring

M. Hall, C. Stauffacher, Lake N. Paul, 2011, Protein science : a publication of the Protein Society.

Mevalonate 5-diphosphate mediates ATP binding to the mevalonate diphosphate decarboxylase from the bacterial pathogen Enterococcus faecalis

Chun-Liang Chen, C. Stauffacher, Lake N. Paul, 2017, The Journal of Biological Chemistry.

Characterization of the Proteome of Cytoplasmic Lipid Droplets in Mouse Enterocytes after a Dietary Fat Challenge

Devika Sirohi, R. Kuhn, A. Greenberg, 2015, PloS one.

Perturbation of the Monomer–Monomer Interfaces of the Benzoylformate Decarboxylase Tetramer

M. McLeish, Lake N Paul, F. Andrews, 2014, Biochemistry.

Purdue e-Pubs Purdue e-Pubs AMP-Activated Protein Kinase Directly Phosphorylates and AMP-Activated Protein Kinase Directly Phosphorylates and Destabilizes Hedgehog Pathway Transcription Factor GLI1 in Destabilizes Hedgehog Pathway Transcription Factor GLI1 in Medulloblastoma Medulloblastoma

M. Scott, A. Brunet, S. Kuang, 2020 .

Hsp31 Is a Stress Response Chaperone That Intervenes in the Protein Misfolding Process*

T. Hazbun, J. Rochet, Lake N. Paul, 2015, The Journal of Biological Chemistry.

AAV analysis by sedimentation velocity analytical ultracentrifugation: beyond empty and full capsids

J. Burgner, Lake N Paul, Valeria Zai-Rose, 2023, European Biophysics Journal.

Ligand-induced Dimerization of Middle East Respiratory Syndrome (MERS) Coronavirus nsp5 Protease (3CLpro)

Arun K. Ghosh, A. Mesecar, Sarah E. St. John, 2015, The Journal of Biological Chemistry.

Ligand-induced Dimerization of Middle East Respiratory Syndrome (MERS) Coronavirus nsp5 Protease (3CL) IMPLICATIONS FOR nsp5 REGULATION AND THE DEVELOPMENT OF ANTIVIRALS*

Arun K. Ghosh, A. Mesecar, M. Denison, 2015 .

A Conserved Acidic Residue in Phenylalanine Hydroxylase Contributes to Cofactor Affinity and Catalysis

Julian E. Fuchs, K. Liedl, C. Das, 2014, Biochemistry.

An additional substrate binding site in a bacterial phenylalanine hydroxylase

Julian E. Fuchs, K. Liedl, C. Das, 2013, European Biophysics Journal.

Stabilization of an unusual salt bridge in ubiquitin by the extra C-terminal domain of the proteasome-associated deubiquitinase UCH37 as a mechanism of its exo specificity.

M. Lill, M. E. Morrow, C. Das, 2013, Biochemistry.

An asymmetric heterodomain interface stabilizes a response regulator–DNA complex

D. Yernool, Anoop Narayanan, Lake N Paul, 2014, Nature Communications.

Crystal structure and characterization of coiled-coil domain of the transient receptor potential channel PKD2L1.

D. Yernool, K. Molland, Lake N. Paul, 2012, Biochimica et biophysica acta.

Folding dynamics of phenylalanine hydroxylase depends on the enzyme’s metallation state: the native metal, iron, protects against aggregate intermediates

L. Stanciu, A. Ribbe, J. A. Ronau, 2011, European Biophysics Journal.

Synthesis of 2-hydroxypropyl-β-cyclodextrin/pluronic-based polyrotaxanes via heterogeneous reaction as potential Niemann-Pick type C therapeutics.

D. Thompson, S. Hyun, M. Wirth, 2013, Biomacromolecules.

Structural and thermodynamic comparison of the catalytic domain of AMSH and AMSH-LP: nearly identical fold but different stability.

C. Das, Lake N Paul, C. Davies, 2011, Journal of molecular biology.

Relationships Between Plasminogen-Binding M-Protein and Surface Enolase for Human Plasminogen Acquisition and Activation in Streptococcus pyogenes

V. Fischetti, F. Castellino, V. Ploplis, 2022, Frontiers in Microbiology.

Wolbachia Endosymbionts Modify Drosophila Ovary Protein Levels in a Context-Dependent Manner

E. Nakayasu, Lake N. Paul, Lake N Paul, 2016, Applied and Environmental Microbiology.

Effect of cross-linking of interfacial sodium caseinate by natural processing on the oxidative stability of oil-in-water (o/w) emulsions.

G. Narsimhan, Lake N. Paul, Pui Yeu Phoon, 2014, Journal of agricultural and food chemistry.

Structure-Function Studies of DNA Binding Domain of Response Regulator KdpE Reveals Equal Affinity Interactions at DNA Half-Sites

Pravindra Kumar, D. Yernool, D. Patil, 2012, PloS one.

Synthesis, characterization, and evaluation of pluronic-based β-cyclodextrin polyrotaxanes for mobilization of accumulated cholesterol from Niemann-Pick type C fibroblasts.

D. Thompson, S. Hyun, M. Wirth, 2013, Biochemistry.