R. Tedesco

发表

Synthesis and structure-activity relationships of imidazo[1,2-a]pyrimidin-5(1H)-ones as a novel series of beta isoform selective phosphatidylinositol 3-kinase inhibitors.

J. F. Mack, J. Luengo, Ramona N Plant, 2012, Bioorganic & medicinal chemistry letters.

Discovery of the First Potent and Selective Inhibitor of Centromere-Associated Protein E: GSK923295.

J. D. Elliott, Nicholas D. Adams, X. Qian, 2010, ACS medicinal chemistry letters.

Synthesis and biological activity of heteroaryl 3-(1,1-dioxo-2H-(1,2,4)-benzothiadizin-3-yl)-4-hydroxy-2(1H)-quinolinone derivatives as hepatitis C virus NS5B polymerase inhibitors.

Adam T. Gates, R. Sarisky, D. Dhanak, 2009, Bioorganic & medicinal chemistry letters.

Estrogen pyrazoles: defining the pyrazole core structure and the orientation of substituents in the ligand binding pocket of the estrogen receptor.

J. Katzenellenbogen, S. Stauffer, Y. Huang, 2001, Bioorganic & medicinal chemistry.

The estrogen receptor: a structure-based approach to the design of new specific hormone-receptor combinations.

B. Katzenellenbogen, J. Katzenellenbogen, J. A. Thomas, 2001, Chemistry & biology.

Novel Stereoselective Synthesis of 11.beta.-Carbon-Substituted Estradiol Derivatives

R. Tedesco, E. Napolitano, R. Fiaschi, 1995 .

Rational Design, Synthesis, and SAR of a Novel Thiazolopyrimidinone Series of Selective PI3K-beta Inhibitors.

J. F. Mack, J. Luengo, Ramona N Plant, 2012, ACS medicinal chemistry letters.

Synthesis and structure-activity relationships of 1,2,4-triazolo[1,5-a]pyrimidin-7(3H)-ones as novel series of potent β isoform selective phosphatidylinositol 3-kinase inhibitors.

J. Luengo, Ramona N Plant, K. Erhard, 2012, Bioorganic & medicinal chemistry letters.

Substituted benzothiadizine inhibitors of Hepatitis C virus polymerase.

Dashyant Dhanak, Adam T. Gates, R. Sarisky, 2009, Bioorganic & medicinal chemistry letters.

Pyrazole ligands: structure-affinity/activity relationships and estrogen receptor-alpha-selective agonists.

B. Katzenellenbogen, J. Katzenellenbogen, K. Carlson, 2000, Journal of medicinal chemistry.

3-(1,1-dioxo-2H-(1,2,4)-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinones, potent inhibitors of hepatitis C virus RNA-dependent RNA polymerase.

Dashyant Dhanak, Adam T. Gates, G. Hofmann, 2006, Journal of medicinal chemistry.

AN EXPEDITIOUS ROUTE TO 7α-SUBSTITUTED ESTRADIOL DERIVATIVES

J. Katzenellenbogen, R. Tedesco, E. Napolitano, 1997 .

6‐Oxoestradiols from Estradiols: Exploiting Site Selective Metalation of Aralkyl Systems with Superbases.

R. Tedesco, E. Napolitano, R. Fiaschi, 1996 .

Arresting Initiation of Hepatitis C Virus RNA Synthesis Using Heterocyclic Derivatives*

Dashyant Dhanak, Kevin J. Duffy, C. Kao, 2003, The Journal of Biological Chemistry.

Synthesis and evaluation of hexahydrochrysene and tetrahydrobenzofluorene ligands for the estrogen receptor.

J. Katzenellenbogen, S. R. Wilson, J A Katzenellenbogen, 2001, Bioorganic & medicinal chemistry letters.

7α,11β-Disubstituted estrogens: Probes for the shape of the ligand binding pocket in the estrogen receptor

J. Katzenellenbogen, R. Tedesco, E. Napolitano, 1997 .

Novel Stereoselective Synthesis of 11β‐Carbon‐Substituted Estradiol Derivatives.

R. Tedesco, E. Napolitano, R. Fiaschi, 1995 .

Discovery of a Novel 2,6-Disubstituted Glucosamine Series of Potent and Selective Hexokinase 2 Inhibitors.

Yong Jiang, Jacques Briand, Junya Qu, 2016, ACS medicinal chemistry letters.