R. Xie

发表

Synthesis and structure-activity relationships of imidazo[1,2-a]pyrimidin-5(1H)-ones as a novel series of beta isoform selective phosphatidylinositol 3-kinase inhibitors.

J. F. Mack, J. Luengo, Ramona N Plant, 2012, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of novel 8- substituted sampangine derivatives as potent inhibitor of Zn2+-Aβ complex mediated toxicity, oxidative stress and inflammation.

R. Xie, Huang Tang, Wei Li, 2021, Bioorganic chemistry.

Novel sampangine derivatives as potent inhibitors of Cu2+-mediated amyloid-β protein aggregation, oxidative stress and inflammation.

R. Xie, Huang Tang, Wei Li, 2021, International journal of biological macromolecules.

Rational Design, Synthesis, and SAR of a Novel Thiazolopyrimidinone Series of Selective PI3K-beta Inhibitors.

J. F. Mack, J. Luengo, Ramona N Plant, 2012, ACS medicinal chemistry letters.

Benzodioxocin-3-ones and N-acyl-3-amino-3-buten-2-ones: novel classes of cathepsin K cysteine protease inhibitors.

D. Veber, M. Hemling, D. Yamashita, 2004, The journal of peptide research : official journal of the American Peptide Society.

Electrochemical Synthesis of 1-Naphthols by Intermolecular Annulation of Alkynes with 1,3-Dicarbonyl Compounds.

Yingming Pan, R. Xie, Haitao Tang, 2019, Organic letters.

Structure activity relationships of 5-, 6-, and 7-methyl-substituted azepan-3-one cathepsin K inhibitors.

Baoguang Zhao, M. Head, D. Veber, 2006, Journal of medicinal chemistry.

2,3,5-Trisubstituted pyridines as selective AKT inhibitors-Part I: Substitution at 2-position of the core pyridine for ROCK1 selectivity.

J. Luengo, D. Yamashita, D. Heerding, 2010, Bioorganic & medicinal chemistry letters.

Tetrasubstituted pyridines as potent and selective AKT inhibitors: Reduced CYP450 and hERG inhibition of aminopyridines.

Sharad Verma, Kristin K. Brown, Anthony E Choudhry, 2010, Bioorganic & medicinal chemistry letters.

Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered through X-ray Fragment Screening.

C. Murray, F. Holding, V. Berdini, 2016, Journal of medicinal chemistry.

Discovery of a Novel 2,6-Disubstituted Glucosamine Series of Potent and Selective Hexokinase 2 Inhibitors.

Yong Jiang, Jacques Briand, Junya Qu, 2016, ACS medicinal chemistry letters.

2,3,5-Trisubstituted pyridines as selective AKT inhibitors. Part II: Improved drug-like properties and kinase selectivity from azaindazoles.

Kristin K. Brown, J. Luengo, Rakesh Kumar, 2010, Bioorganic & medicinal chemistry letters.

Azepanone-based inhibitors of human cathepsin L.

Y. Ru, M. Head, D. Veber, 2005, Journal of medicinal chemistry.