M. Iatropoulos

发表

M. Iatropoulos, 2000 .

Mechanisms of DNA-reactive and epigenetic chemical carcinogens: applications to carcinogenicity testing and risk assessment.

Gary M Williams, M. Iatropoulos, T. Kobets, 2019, Toxicology research.

Carcinogenicity of Chemicals: Assessment and Human Extrapolation

Gary M Williams, U. Deschl, H. Enzmann, 2014 .

Agents inducing forestomach neoplasms in rodents-An overview

G. Williams, I. Modlin, E. Dybing, 2005 .

Short- and intermediate-term carcinogenicity testing--a review. Part 1: the prototypes mouse skin tumour assay and rat liver focus assay.

G. Williams, H. Ahr, H. Enzmann, 1998, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Absorption, transport and organotropism of dichlorobiphenyl (DCB), dieldrin, and hexachlorobenzene (HCB) in rats.

M. Iatropoulos, 1975, Environmental research.

Risk assessment of carcinogens in food with special consideration of non-genotoxic carcinogens. Scientific arguments for use of risk assessment and for changing the Delaney Clause specifically.

P. Fenner-Crisp, G. Williams, J. Weisburger, 1996, Experimental and Toxicological Pathology.

Initiating activity of the anti-estrogen tamoxifen, but not toremifene in rat liver.

S. Karlsson, G. Williams, M. Iatropoulos, 1997, Carcinogenesis.

The Histopathology of Kidney Changes in Rats and Monkeys Following Intravenous Administration of Massive Doses of FCE 26184, Human Basic Fibroblast Growth Factor

Gary M Williams, A. Newman, G. Hard, 1993, Toxicologic pathology.

Endocrine considerations in toxicologic pathology.

M. Iatropoulos, 1994, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

Morphological effects of hexachlorobenzene toxicity in female rhesus monkeys.

W. Hobson, M. Iatropoulos, V. Knauf, 1976, Toxicology and applied pharmacology.

The Function and Pathology of Brown Adipose Tissue in Animals and Humans

Gary M Williams, M. Iatropoulos, G. Williams, 2004 .

Increased expression of cyclooxygenase-2 in rat lung tumors induced by the tobacco-specific nitrosamine 4-(methylnitrosamino)-4-(3-pyridyl)-1-butanone: the impact of a high-fat diet.

E. Wynder, S. Amin, D. Hoffmann, 1999, Cancer research.

First Conference of the International Federation of Societies of Toxicologic Pathologists (IFSTP)

L. Tryphonas, M. Iatropoulos, Frej Stenbäuck, 1993 .

The triphenylethylene drug tamoxifen is a strong liver carcinogen in the rat.

G. Williams, M. Djordjevic, M. Iatropoulos, 1993, Carcinogenesis.

Major difference in the hepatocarcinogenicity and DNA adduct forming ability between toremifene and tamoxifen in female Crl:CD(BR) rats.

G. Williams, G. Hard, M. Iatropoulos, 1993, Cancer research.

Inhibitory effect of green tea in the drinking water on tumorigenesis by ultraviolet light and 12-O-tetradecanoylphorbol-13-acetate in the skin of SKH-1 mice.

Y. Lou, M. Huang, A. Conney, 1992, Cancer research.

Short- and intermediate-term carcinogenicity testing--a review. Part 2: available experimental models.

G. Williams, H. Ahr, H. Enzmann, 1998, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Histopathology of interscapular brown adipose tissue, thyroid, and pancreas in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-treated rats.

M. Iatropoulos, K. Rozman, D. Pereira, 1986, Toxicology and applied pharmacology.

Elevated plasma corticosterone levels and histopathology of the adrenals and thymuses in 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated rats.

G. Muzi, L. Weber, M. Iatropoulos, 1988, Toxicology.

Some Endocrine and Morphological Aspects of the Acute Toxicity of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD)

G. Muzi, L. Weber, M. Iatropoulos, 1988, Toxicologic pathology.

Chicken fetal liver DNA damage and adduct formation by activation-dependent DNA-reactive carcinogens and related compounds of several structural classes.

Gary M Williams, U. Deschl, M. Iatropoulos, 2014, Toxicological sciences : an official journal of the Society of Toxicology.

Comment on Mitoxantrone

A. Yacobi, G. Dukart, M. Iatropoulos, 1985, Drug intelligence & clinical pharmacy.

The Proliferation in Uterine Compartments of Intact Rats of Two Different Strains Exposed to High Doses of Tamoxifen or Toremifene

Gary M Williams, S. Karlsson, L. Kangas, 1998, Toxicologic pathology.

Diethylnitrosamine exposure-responses for DNA damage, centrilobular cytotoxicity, cell proliferation and carcinogenesis in rat liver exhibit some non-linearities.

R. Gebhardt, G. Williams, L. Peterson, 1996, Carcinogenesis.

A study of the mechanism of butachlor-associated gastric neoplasms in Sprague-Dawley rats.

G. Williams, A. Wilson, G. Hard, 1995, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

Safety assessment of new anticancer compound, mitoxantrone, in beagle dogs: comparison with doxorubicin. II. Histologic and ultrastructural pathology.

M. Iatropoulos, J. Noble, G. Gordon, 1982, Cancer treatment reports.

Inhibition of lung carcinogenesis by black tea in Fischer rats treated with a tobacco-specific carcinogen: caffeine as an important constituent.

S. Amin, C. Ho, B. Pittman, 1998, Cancer research.

Inter-laboratory comparison of turkey in ovo carcinogenicity assessment (IOCA) of hepatocarcinogens.

H. Enzmann, M. Moore, I. Todor, 2013, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

Pentachlorophenol (but not Phenobarbital) Promotes Intrahepatic Biliary Cysts Induced by Diethylnitrosamine to Cholangio Cystic Neoplasms in B6C3F1 Mice Possibly Due to Oxidative Stress

Gary M Williams, K. Kanki, A. Nishikawa, 2003, Toxicologic pathology.

The effect of mitoxantrone treatment in beagle dogs previously treated with minimally cardiotoxic doses of doxorubicin.

M. Iatropoulos, W. Dougherty, V. C. James, 1987, The American journal of pathology.

Pre-clinical toxicology and pathology of 9-(2'-hydroxyethylamino)-4-methyl-1-nitroacridine (C-1748), a novel anti-cancer agent in male Beagle dogs.

D. Banerjee, R. Tiwari, K. Tadi, 2006, Life sciences.

Dose-dependent induction of preneoplastic lesions by the tobacco-specific nitrosamine carcinogen NNK in the in ovo carcinogenicity assessment (IOCA) assay.

Gary M Williams, H. Enzmann, M. Iatropoulos, 2014, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

Coxsackievirus in an Infant Chimpanzee

K. Soike, M. Iatropoulos, M. Kelly, 1978, Journal of medical primatology.

Anthracyclines - a review of general and special toxicity studies.

S. Castellino, D. Moneta, M. Brughera, 1995, International journal of oncology.

The natural basil flavonoid nevadensin protects against a methyleugenol-induced marker of hepatocarcinogenicity in male F344 rat.

Gary M Williams, I. Rietjens, A. Jeffrey, 2014, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Methyleugenol hepatocellular cancer initiating effects in rat liver.

Gary M Williams, A. Jeffrey, M. Iatropoulos, 2013, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Increased expression of cyclooxygenase-2 in rat lung tumors induced by the tobacco-specific nitrosamine 4-(methylnitrosamino)-4-(3-pyridyl)-1-butanone: the impact of a high-fat diet.

E. Wynder, S. Amin, D. Hoffmann, 1999, Cancer research.

Haematology and clinical chemistry in rats: Comparison of different blood collection sites

M. Brughera, M. Iatropoulos, G. Mazué, 1996, Comparative Haematology International.

Alteration of Liver Cell Function and Proliferation: Differentiation Between Adaptation and Toxicity

Gary M Williams, M. Iatropoulos, Michael J Iatropoulos, 2002, Toxicologic pathology.

Acrylonitrile induction of rodent neoplasia: Potential mechanism of action and relevance to humans

Gary M Williams, M. Iatropoulos, T. Kobets, 2022, Toxicology Research and Application.

Safety assessment of butylated hydroxyanisole and butylated hydroxytoluene as antioxidant food additives.

G. Williams, G M Williams, J Whysner, 1999, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Dose response of promotion by butylated hydroxyanisole in chemically initiated tumours of the rat forestomach.

G. Williams, M. Iatropoulos, J. Whysner, 1994, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Hyperpigmentation of the skin associated with minocycline therapy.

M. Iatropoulos, G. Gordon, B. Sparano, 1985, Archives of dermatology.

Thyroid gland pigmentation and minocycline therapy.

M. Iatropoulos, G. Gordon, A. W. Kramer, 1984, The American journal of pathology.

Mechanistic studies on genotoxicity and carcinogenicity of salicylazosulfapyridine an anti-inflammatory medicine.

G. Williams, F. Kari, M. Iatropoulos, 1997, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

Urinary bladder hyperplasia in the rat: non-specific pathogenetic considerations using a beta-lactam antibiotic.

A. Dayan, A. Newman, M. Brughera, 1994, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

Inhibition of the hepatocarcinogenicity of aflatoxin B1 in rats by low levels of the phenolic antioxidants butylated hydroxyanisole and butylated hydroxytoluene.

G. Williams, M. Iatropoulos, 1996, Cancer letters.

Aging‐associated changes in gene expression in the ACI rat prostate: Implications for carcinogenesis

N. Reyes, J. Geliebter, A. Mittelman, 2005, The Prostate.

Cytoarchitecture of rat liver during compensatory growth

M. Iatropoulos, 1971, The Anatomical record.

Toxicological testing of cytotoxic drugs (review).

P. Colombo, M. Brughera, M. Iatropoulos, 2001, International journal of oncology.

A no observed adverse effect level for DNA adduct formation in rat liver with prolonged dosing of the hepatocarcinogen 2-acetylaminofluorene

M. Iatropoulos, T. Kobets, Jian-Dong Duan, 2015 .

Assessment of chronic toxicity and carcinogenicity in an accelerated cancer bioassay in rats of Nifurtimox, an antitrypanosomiasis drug.

G. Williams, M. Iatropoulos, C. X. Wang, 2006, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

Long term safety evaluation of 3-phenyl-5beta-diethylaminoethyl-1,2,4-oxadiazole. I. In Charles River mice.

T. B. Griffin, E. McChesney, F. Coulston, 1978, Experimental and molecular pathology.

Inhibition by acetaminophen of neoplastic initiation elicited in rat liver by the DNA-reactive hepatocarcinogen N-acetyl-2-aminofluorene

C. Perrone, A. Jeffrey, M. Iatropoulos, 2007, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation.

Diethylnitrosamine exposure-responses for DNA ethylation, hepatocellular proliferation, and initiation of carcinogenesis in rat liver display non-linearities and thresholds

Chung-Xiou Wang, B. Pittman, A. Jeffrey, 1999, Archives of Toxicology.

Hepatocellular proliferation and hepatocarcinogen bioactivation in mice with diet-induced fatty liver and obesity.

M. Leach, G. Williams, A. Jeffrey, 2013, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

Nonlinearities in 2-acetylaminofluorene exposure responses for genotoxic and epigenetic effects leading to initiation of carcinogenesis in rat liver.

R. Gebhardt, G. Williams, B. Pittman, 1998, Toxicological sciences : an official journal of the Society of Toxicology.

Mechanistic Basis for Nonlinearities and Thresholds in Rat Liver Carcinogenesis by the DNA-Reactive Carcinogens 2-Acetylaminofluorene and Diethylnitrosamine

G M Williams, A. Jeffrey, A M Jeffrey, 2000, Toxicologic pathology.

Nasal Cytotoxic and Carcinogenic Activities of Systemically Distributed Organic Chemicals

A. Jeffrey, M. Iatropoulos, G. Williams, 2006, Toxicologic pathology.

Butylated hydroxytoluene lacks the activity of phenobarbital in enhancing diethylnitrosamine-induced mouse liver carcinogenesis.

G. Williams, M. Iatropoulos, K. Tokumo, 1991, Cancer letters.

Assessment of chronic toxicity and carcinogenicity in an accelerated cancer bioassay in rats of moxifloxacin, a quinolone antibiotic.

G. Williams, A. Jeffrey, H. Enzmann, 2001, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

Cellular proliferation and secretion in the adenohypophysis of diethylstilbestrol-treated rats.

G. Delides, M. Iatropoulos, 1979, Environmental research.

Expression of Genes Encoding for Xenobiotic Metabolism After Exposure to Dialkylnitrosamines in the Chicken Egg Genotoxicity Alternative Model

U. Deschl, D. Iacobas, S. Iacobaş, 2018, Toxicological sciences : an official journal of the Society of Toxicology.

Nitric oxide-donating aspirin prevents pancreatic cancer in a hamster tumor model.

Jianjun Gao, L. Kopelovich, K. Kashfi, 2006, Cancer research.

Principles of Testing for Carcinogenic Activity

Harald Enzmann, Gary M. Williams, H. Enzmann, 2007 .

Identity and pathogenesis of stomach tumors in Sprague-Dawley rats associated with the dietary administration of butachlor.

M. Tatematsu, G. Williams, A. Wilson, 1995, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

Appropriateness of Methods for Slide Evaluation in the Practice of Toxicologic Pathology

M. Iatropoulos, 1984, Toxicologic pathology.

Evaluation of 4′-Iodo-4′-Deoxydoxorubicin-Induced Cardiotoxicity in Two Experimental Rat Models

M. Brughera, M. Iatropoulos, G. Mazué, 1994, Toxicologic pathology.

In ovo carcinogenicity assay (IOCA): evaluation of mannitol, caprolactam and nitrosoproline

Gary M. Williams, C. Perrone, H. Enzmann, 2002, Archives of Toxicology.

Chicken egg fetal liver DNA and histopathologic effects of structurally diverse carcinogens and non-carcinogens.

G. Williams, U. Deschl, M. Iatropoulos, 2017, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

Multicenter study to assess potential hazards from exposure to lipid peroxidation products in soya bean oil from Trilucent breast implants.

R. Browne, H. Bartsch, G. Williams, 2009, Regulatory toxicology and pharmacology : RTP.

Pathologist's Responsibility in the Diagnosis of Oncogenesis

M. Iatropoulos, Michael J. Iatropoulos, 1983, Toxicologic pathology.

Long-Lasting Effect of Dexrazoxane Against Anthracycline Cardiotoxicity in Rats

M. Iatropoulos, G. Mazué, Paola Della Torre, 1996, Toxicologic pathology.

Chemical carcinogen mechanisms of action and implications for testing methodology.

G. Williams, J. Weisburger, M. Iatropoulos, 1996, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

Thresholds for DNA-Reactive (Genotoxic) Organic Carcinogens

Gary M. Williams, A. Jeffrey, Michael J. Iatropoulos, 2005 .

Thresholds for the Effects of 2-Acetylaminofluorene in Rat Liver

A. Jeffrey, M. Iatropoulos, G. Williams, 2004, Toxicologic pathology.

Proliferation markers.

G. Williams, M. Iatropoulos, Gary M. Williams, 1996, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

In ovo testing of flavor and fragrance materials in Turkey Egg Genotoxicity Assay (TEGA), comparison of results to in vitro and in vivo data.

M. Iatropoulos, T. Kobets, K. Brunnemann, 2018, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Inhibition by dietary hydroquinone of acetylaminofluorene induction of initiation of rat liver carcinogenesis.

A. Jeffrey, M. Iatropoulos, Jian-Dong Duan, 2007, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Assessment of DNA Binding and Oxidative DNA Damage by Acrylonitrile in Two Rat Target Tissues of Carcinogenicity: Implications for the Mechanism of Action.

M. Iatropoulos, T. Kobets, Jian-Dong Duan, 2017, Chemical research in toxicology.

Evaluation of potential human carcinogenicity of the synthetic monomer ethyl acrylate.

M. Iatropoulos, G. Williams, 2009, Regulatory toxicology and pharmacology : RTP.

Sex differences in DNA damage produced by the carcinogen 2-acetylaminofluorene in cultured human hepatocytes compared to rat liver and cultured rat hepatocytes

C. Perrone, M. Iatropoulos, Jian-Dong Duan, 2014, Archives of Toxicology.

Intestinal carcinogenesis in rats using 1,2-dimethylhydrazine with or without degraded carrageenan.

F. Coulston, L. Golberg, M. Iatropoulos, 1975, Experimental and molecular pathology.

Correlation of relaxometry and histopathology: the transplantable human gliobastoma SF295 grown in athymic nude mice

M. Spiller, S. Kasoff, M. Iatropoulos, 2005, Journal of Neuro-Oncology.

Toxicity studies of butylated hydroxyanisole and butylated hydroxytoluene. II. Chronic feeding studies.

G. Williams, M. Iatropoulos, C. X. Wang, 1990, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Consensus Diagnoses and Mode of Action for the Formation of Gastric Tumors in Rats Treated with the Chloroacetanilide Herbicides Alachlor and Butachlor

T. Harada, S. Furukawa, M. Iatropoulos, 2014, Toxicologic pathology.

Morphologic effects of 3,4',5-tribromosalicylanilide in male rats.

K. Benitz, F. Coulston, M. Iatropoulos, 1974, Toxicology and applied pharmacology.

Response of nursing infant rhesus to clophen A-30 or hexachlorobenzene given to their lactating mothers.

F. Coulston, W. Hobson, M. Iatropoulos, 1978, Environmental research.

The urinary bladder carcinogen propoxur does not produce genotoxic effects in the urinary bladder of Wistar male rats.

G. Williams, G. Schmuck, M. Iatropoulos, 2015, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

Long-term prophylactic use of tamoxifen: is it safe?

G. Williams, G. Hard, M. Iatropoulos, 1992, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation.

Methotrexate: Assessment of In Vivo Clastogenicity and Carcinogenicity

M. Iatropoulos, J. Noble, M. Manandhar, 1988, Toxicologic pathology.

Microarray analysis of diet-induced alterations in gene expression in the ACI rat prostate.

N. Reyes, J. Geliebter, A. Mittelman, 2002, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation.

Reduction by Dietary Matrix Metalloproteinase Inhibitor BAY 12-9566N of Neoplastic Development Induced by Diethylnitrosamine, N-nitrosodimethylamine, or 7,12-dimethylbenz(a)anthracene in Rats

M. Iatropoulos, D. Cerven, G. Degeorge, 2008 .

Bioassay of mannitol and caprolactam and assessment of response to diethylnitrosamine in heterozygous p53-deficient (+/-) and wild type (+/+) mice

G. Schlüter, A. Jeffrey, H. Enzmann, 2001, Archives of Toxicology.

Sex differences in DNA damage produced by the carcinogen 2-acetylaminofluorene in cultured human hepatocytes compared to rat liver and cultured rat hepatocytes

C. Perrone, M. Iatropoulos, Jian-Dong Duan, 2016, Archives of Toxicology.

Protective effect of acetaminophen against colon cancer initiation effects of 3,2′-dimethyl-4-aminobiphenyl in rats

T. Shirai, A. Jeffrey, M. Iatropoulos, 2002, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation.

Morphologic Changes in the Gastric Mucosa of Rats and Dogs Treated with an Analog of Prostaglandin E1

M. Iatropoulos, W. Dougherty, Alfred W. Kramer, 1985, Toxicologic pathology.

GRAS determination scientific procedures and possible alternatives.

M. Iatropoulos, T. Kobets, K. Brunnemann, 2016, Regulatory toxicology and pharmacology : RTP.

Assessment of chronic toxicity and carcinogenicity in rats of Wingstay 100, a rubber antioxidant/antiozonant.

G. Williams, M. Iatropoulos, K. Brunnemann, 1997, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

N-ethyl-N-nitrosourea induced brain tumors in rats monitored by nuclear magnetic resonance imaging, plasma proton nuclear magnetic resonance spectroscopy and microscopy.

S. Amin, G. Williams, S. Hecht, 1992, Cancer letters.

Effect of a Sublethal Dose of 2,3,7,8-Tetrachlorodibenzo-p-dioxin on Interscapular Brown Adipose Tissue of Rats

M. Iatropoulos, K. Rozman, D. Pereira, 1987, Toxicologic pathology.

An introduction to endocrine modulators.

M. Iatropoulos, 2000, Toxicologic pathology.

Inhibition by acetaminophen of intestinal cancer in rats induced by an aromatic amine similar to food mutagens

M. Iatropoulos, G. Williams, 1997, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation.

Consensus Diagnoses and Mode of Action for the Formation of Gastric Tumors in Rats Treated with the Chloroacetanilide Herbicides Alachlor and Butachlor

T. Harada, S. Furukawa, M. Iatropoulos, 2014, Toxicologic pathology.

Dose-dependent induction of preneoplastic lesions by the tobacco-specific nitrosamine carcinogen NNK in the in ovo carcinogenicity assessment (IOCA) assay.

H. Enzmann, M. Iatropoulos, K. Brunnemann, 2014, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.