Marco Spiga

发表

Easy access to trans-2,3-disubstituted cyclobutanones, 2,4,5-trisubstituted 3,6-dihydro-2H-pyrans and cis-substituted phenylcyclopropylsulfones by using the highly versatile 1-phenylsulfenyl- or 1-phenylsulfonyl-cyclopropylketones.

C. Floris, Francesco Secci, G. Alberti, 2009, Organic & biomolecular chemistry.

Very high stereoselectivity in organocatalyzed desymmetrizing aldol reactions of 3-substituted cyclobutanones.

Francesco Secci, R. Guillot, D. Aitken, 2012, Organic & biomolecular chemistry.

Development of novel ADCs: conjugation of tubulysin analogues to trastuzumab monitored by dual radiolabeling.

G. V. van Dongen, M. Zanda, P. Lazzari, 2014, Cancer research.

Synthesis of enantiomerically enriched secondary and tertiary phenylthio- and phenoxy-aldols

Francesco Secci, Angelo Frongia, A. Bernard, 2008 .

l-Proline-catalyzed direct intermolecular asymmetric aldol reactions of 1-phenylthiocycloalkyl carboxaldehydes with ketones. Easy access to spiro- and fused-cyclobutyl tetrahydrofurans and cyclopentanones.

Francesco Secci, R. Guillot, Angelo Frongia, 2007, Organic letters.

A highly stereocontrolled formal total synthesis of (±)- and of (−)-grandisol by 1,4-conjugated addition of organocopper reagents to cyclobutylidene derivatives

Francesco Secci, J. Ollivier, Angelo Frongia, 2007 .

Easy access to trans-2,3-disubstituted cyclobutanones, 2,4,5-trisubstituted 3,6-dihydro-2H-pyrans and cis-substituted phenylcyclopropylsulfones by using the highly versatile 1-phenylsulfenyl- or 1-phenylsulfonyl-cyclopropylketones.

C. Floris, Francesco Secci, G. Alberti, 2009, Organic & biomolecular chemistry.

Stereoselective preparation of β,γ-methano-GABA derivatives.

R. Guillot, D. Aitken, J. Ollivier, 2011, Organic & biomolecular chemistry.

Regioselective Synthesis of Trisubstituted 2,3-Dihydrofurans from Donor−Acceptor Cyclopropanes or from Reaction of the Corey Ylide with α-Sulfenyl-, α-Sulfinyl-, or α-Sulfonylenones

Francesco Secci, Angelo Frongia, A. Bernard, 2005 .

Oxaspiropentane derivatives as effective sex pheromone analogues in the gypsy moth: electrophysiological and behavioral evidence.

R. Crnjar, Francesco Secci, G. Sollai, 2007, Chemical senses.

KEMTUB012-NI2, a novel potent tubulysin analog that selectively targets hypoxic cancer cells and is potentiated by cytochrome p450 reductase downregulation

M. Zanda, P. Lazzari, I. Fleming, 2017, Hypoxia.

Synthesis and Superpotent Anticancer Activity of Tubulysins Carrying Non-hydrolysable N-Substituents on Tubuvaline.

N. Zaffaroni, M. Zanda, P. Lazzari, 2017, Chemistry.

KEMTUB 012-NI 2 , a novel potent tubulysin analog that selectively targets hypoxic cancer cells and is potentiated by cytochrome p 450 reductase downregulation

M. Zanda, P. Lazzari, I. Fleming, 2017 .

Synthesis and cytotoxicity evaluation of diastereoisomers and N-terminal analogues of tubulysin-U

M. Zanda, P. Lazzari, P. Shankar, 2013 .

The First Organocatalysed Direct Aldol Reaction of 2-Hydroxycyclobutanone

Francesco Secci, R. Guillot, D. Aitken, 2011 .