D. Skalitzky

发表

Prins cyclization of 4-allyl-1,3-dioxanes prepared from 1,3-diol synthons. A rapid entry into functionalized tetrahydropyrans

S. Rychnovsky, Yueqing Hu, D. Skalitzky, 1996 .

Discovery of potent selective bioavailable phosphodiesterase 2 (PDE2) inhibitors active in an osteoarthritis pain model. Part II: optimization studies and demonstration of in vivo efficacy.

J. Pandit, C. Whitehead, Cindy Spessard, 2013, Bioorganic & medicinal chemistry letters.

Potentiation of cytotoxic drug activity in human tumour cell lines, by amine-substituted 2-arylbenzimidazole-4-carboxamide PARP-1 inhibitors.

N. Curtin, R. Griffin, B. Golding, 2004, Bioorganic & medicinal chemistry letters.

Tricyclic benzimidazoles as potent poly(ADP-ribose) polymerase-1 inhibitors.

N. Curtin, R. Griffin, B. Golding, 2003, Journal of medicinal chemistry.

Stereochemistry of alternating polyol chains: 13C NMR analysis of 1,3-diol acetonides

S. Rychnovsky, D. Skalitzky, Donald J. Skalitzky, 1990 .

Solid-phase synthesis of irreversible human rhinovirus 3C protease inhibitors. Part 1: Optimization of tripeptides incorporating N-terminal amides.

P. Dragovich, S. Worland, J. Meador, 1999, Bioorganic & medicinal chemistry.

Stereochemistry of the macrolactins

P. Jensen, W. Fenical, S. Rychnovsky, 1992 .

Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361.

Robert Almassy, Kaye J Williams, N. Curtin, 2004, Journal of the National Cancer Institute.

Discovery of LYC-55716: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor-γ (RORγ) Agonist for Use in Treating Cancer.

P. Toogood, Tao Zheng, G. Glick, 2021, Journal of medicinal chemistry.

A practical preparation of .alpha.-alkoxylithium reagents: synthesis of syn or anti 1,3-diols

S. Rychnovsky, D. Skalitzky, 1992 .

Optically pure 1,3-diols from (2R,4R)- and (2S,4S)-1,2:4,5-diepoxypentane

S. Rychnovsky, S. Zeller, D. Skalitzky, 1991 .

Synthesis, Equilibration, and Coupling of 4-Lithio-1,3-dioxanes: Synthons for syn- and anti-1,3-Diols.

S. Rychnovsky, A. Buckmelter, D. Skalitzky, 1999, The Journal of organic chemistry.

Design, synthesis, and biological evaluation of novel human 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP) substrates.

L. Kuhn, P. W. Rose, P. Kung, 2005, Bioorganic & Medicinal Chemistry Letters.

Discovery of potent, selective, bioavailable phosphodiesterase 2 (PDE2) inhibitors active in an osteoarthritis pain model, part I: transformation of selective pyrazolodiazepinone phosphodiesterase 4 (PDE4) inhibitors into selective PDE2 inhibitors.

Howard Miller, J. Pandit, C. Whitehead, 2013, Bioorganic & medicinal chemistry letters.

Preclinical selection of a novel poly(ADP-ribose) polymerase inhibitor for clinical trial

N. Curtin, D. Newell, Lan Z. Wang, 2007, Molecular Cancer Therapeutics.

Synthetic RORγ agonists regulate multiple pathways to enhance antitumor immunity

P. Toogood, K. Majchrzak, G. Glick, 2016, Oncoimmunology.

Identification of potent nontoxic poly(ADP-Ribose) polymerase-1 inhibitors: chemopotentiation and pharmacological studies.

N. Curtin, B. Durkacz, D. Newell, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Pyridine-3-propanoic acids: Discovery of dual PPARalpha/gamma agonists as antidiabetic agents.

K. Ogilvie, Guy A. McClellan, L. Christie, 2006, Bioorganic & medicinal chemistry letters.

Stereochemistry of the Macrolactins.

P. Jensen, W. Fenical, S. Rychnovsky, 1992 .