P. Barsanti

发表

Structure-Based Drug Design of Novel, Potent, and Selective Azabenzimidazoles (ABI) as ATR Inhibitors.

M. P. Dillon, M. Cox, Yipin Lu, 2015, ACS medicinal chemistry letters.

Structure-Based Drug Design of Novel Potent and Selective Tetrahydropyrazolo[1,5-a]pyrazines as ATR Inhibitors.

Yipin Lu, Jiong Lan, R. Jain, 2015, ACS medicinal chemistry letters.

A Synthetic Lethal Screen Reveals Enhanced Sensitivity to ATR Inhibitor Treatment in Mantle Cell Lymphoma with ATM Loss-of-Function

Yan Tang, Wei Zhang, E. Lees, 2014, Molecular Cancer Research.

4-(Aminoalkylamino)-3-benzimidazole-quinolinones as potent CHK-1 inhibitors.

Z. Ni, D. Bussiere, S. Ramurthy, 2006, Bioorganic & medicinal chemistry letters.

Enantioselective Ring Opening of Epoxides with Silicon Tetrachloride in the Presence of a Chiral Lewis Base: Mechanism Studies

S. Denmark, G. Beutner, P. Barsanti, 2007 .

The intramolecular 1,3-dipolar cyclisation of mesoionic species generated by the thermolysis of the mixed anhydrides of acetic and N-alkynoyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids

P. Woodward, P. Barsanti, M. Sainsbury, 1993 .

The discovery of tetrahydro-beta-carbolines as inhibitors of the kinesin Eg5.

Z. Ni, E. Martin, D. Bussiere, 2012, Bioorganic & medicinal chemistry letters.

Design, structure-activity relationship, and in vivo characterization of the development candidate NVP-HSP990.

Kristin M. Brinner, N. Pryer, T. Hendrickson, 2014, Journal of medicinal chemistry.

Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction

Kathleen A. Boyle, Anjanabha Saha, J. Kuriyan, 2019, Nature Communications.

Rationally Designed PI3Kα Mutants to Mimic ATR and Their Use to Understand Binding Specificity of ATR Inhibitors.

D. Bussiere, Yipin Lu, Li Zhang, 2017, Journal of molecular biology.

Ketone-directed peracid epoxidation of cyclic alkenes

A. Armstrong, A. Wood, P. Clarke, 1996 .

Ketone-directed peracid epoxidation

A. Armstrong, A. Wood, P. Clarke, 1994 .

Enantioselective Ring Opening of Epoxides with Silicon Tetrachloride in the Presence of a Chiral Lewis Base.

S. Denmark, Ken‐Tsung Wong, R. Stavenger, 1998, The Journal of organic chemistry.

Ketone-Directed Peracid Epoxidation.

A. Armstrong, A. Wood, P. Clarke, 1995 .

Preparation of Chlorosilyl Enolates

S. Denmark, Ken‐Tsung Wong, R. Stavenger, 1998 .

Total synthesis of (+)-zaragozic acid C.

A. Armstrong, L. Jones, P. Barsanti, 1998, The Journal of organic chemistry.

Synthesis of the C1-side chain of zaragozic acid D and progress towards a total synthesis

A. Armstrong, R. Ogilvie, P. Barsanti, 2003 .

[A case with XYY karyotype, Mediterranean disease and hypogammaglobulinemia].

L. Bonomo, G. Guanti, D. Trizio, 1970, Acta geneticae medicae et gemellologiae.

Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction

Kathleen A. Boyle, Anjanabha Saha, J. Kuriyan, 2019, Nature Communications.

Design and Discovery of N-(3-(2-(2-Hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide, a Selective, Efficacious, and Well-Tolerated RAF Inhibitor Targeting RAS Mutant Cancers: The Path to the Clinic.

W. Sellers, M. P. Dillon, Y. Mishina, 2020, Journal of medicinal chemistry.

Design and Discovery of N-(2-Methyl-5'-morpholino-6'-((tetrahydro-2H-pyran-4-yl)oxy)-[3,3'-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A Potent, Selective, and Efficacious RAF Inhibitor Targeting RAS Mutant Cancers.

M. P. Dillon, Mallika Singh, E. Lees, 2017, Journal of medicinal chemistry.

Design and Discovery of N-(2-Methyl-5'-morpholino-6'-((tetrahydro-2H-pyran-4-yl)oxy)-[3,3'-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A Potent, Selective, and Efficacious RAF Inhibitor Targeting RAS Mutant Cancers.

M. P. Dillon, Mallika Singh, E. Lees, 2017, Journal of medicinal chemistry.