Sanjeewa A. Goonasekera

发表

Mice with the R176Q cardiac ryanodine receptor mutation exhibit catecholamine-induced ventricular tachycardia and cardiomyopathy

Wei Zhang, Dan M. Roden, Robia G. Pautler, 2006, Proceedings of the National Academy of Sciences.

RyR1 S-Nitrosylation Underlies Environmental Heat Stroke and Sudden Death in Y522S RyR1 Knockin Mice

A. E. Rossi, M. R. Baker, S. Boncompagni, 2008, Cell.

Identification of Cysteines Involved in S-Nitrosylation, S-Glutathionylation, and Oxidation to Disulfides in Ryanodine Receptor Type 1*

S. Hamilton, C. Hidalgo, R. Dirksen, 2006, Journal of Biological Chemistry.

RhoA signaling in cardiomyocytes protects against stress-induced heart failure but facilitates cardiac fibrosis

P. Kang, J. Molkentin, A. Saci, 2014, Science Signaling.

Triadin Binding to the C-Terminal Luminal Loop of the Ryanodine Receptor is Important for Skeletal Muscle Excitation–Contraction Coupling

I. Marty, A. Dulhunty, N. Beard, 2007, The Journal of general physiology.

Na+ Dysregulation Coupled with Ca2+ Entry through NCX1 Promotes Muscular Dystrophy in Mice

J. Molkentin, P. Allen, Jianjie Ma, 2014, Molecular and Cellular Biology.

Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle.

R. Hajjar, J. Molkentin, E. Kranias, 2011, The Journal of clinical investigation.

Dynamic alterations in myoplasmic Ca2+ in malignant hyperthermia and central core disease.

R. Dirksen, Sanjeewa A. Goonasekera, A. Lyfenko, 2004, Biochemical and biophysical research communications.

muscle 3 mo after coronary artery ligation -ATPase properties in rat heart and skeletal

J. Molkentin, P. Allen, S. K. Dasika, 2015 .

Calcium influx is sufficient to induce muscular dystrophy through a TRPC-dependent mechanism

B. Aronow, J. Molkentin, M. Maillet, 2009, Proceedings of the National Academy of Sciences.

Unrestrained p38 MAPK Activation in Dusp1/4 Double-Null Mice Induces Cardiomyopathy

R. Willette, J. Molkentin, J. Lorenz, 2013, Circulation research.

Enhanced Ca²⁺ influx from STIM1-Orai1 induces muscle pathology in mouse models of muscular dystrophy.

J. Molkentin, R. Dirksen, Federica Accornero, 2014, Human molecular genetics.

metabolic flexibility, and propensity for heart failure in mice

J. Farber, J. Molkentin, T. Force, 2010 .

Cyclophilin D controls mitochondrial pore-dependent Ca(2+) exchange, metabolic flexibility, and propensity for heart failure in mice.

J. Farber, J. Molkentin, T. Force, 2010, The Journal of clinical investigation.

Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals

K. Flaherty, J. Costello, J. Wargo, 2012, Nature Medicine.

Ryanodinopathies : Muscle Disorders Linked to Mutations in Ryanodine Receptors

J. Lueck, R. Dirksen, Sanjeewa A. Goonasekera, 2004 .

Novel excitation-contraction uncoupled RYR1 mutations in patients with central core disease

A. E. Rossi, D. Maclennan, R. Dirksen, 2013, Neuromuscular Disorders.

An Ryr1I4895T mutation abolishes Ca2+ release channel function and delays development in homozygous offspring of a mutant mouse line

J. Seidman, A. Gramolini, C. Seidman, 2007, Proceedings of the National Academy of Sciences.

Heat‐ and anesthesia‐induced malignant hyperthermia in an RyR1 knock‐in mouse

J. Lueck, Pumin Zhang, S. Hamilton, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Unraveling the secrets of a double life: contractile versus signaling Ca2+ in a cardiac myocyte.

J. Molkentin, Sanjeewa A. Goonasekera, 2012, Journal of molecular and cellular cardiology.

Epac and Phospholipase Cϵ Regulate Ca2+ Release in the Heart by Activation of Protein Kinase Cϵ and Calcium-Calmodulin Kinase II*

B. Blaxall, R. Dirksen, A. Smrcka, 2009, Journal of Biological Chemistry.

Reconstitution of local Ca2+ signaling between cardiac L-type Ca2+ channels and ryanodine receptors: insights into regulation by FKBP12.6.

R. Dirksen, Sanjeewa A. Goonasekera, S. Chen, 2005, American journal of physiology. Cell physiology.

STIM1 elevation in the heart results in aberrant Ca²⁺ handling and cardiomyopathy.

S. Houser, J. Molkentin, J. V. van Berlo, 2015, Journal of molecular and cellular cardiology.

Sarcolipin overexpression improves muscle energetics and reduces fatigue.

J. Molkentin, Jianjie Ma, N. Weisleder, 2015, Journal of applied physiology.

Decreased cardiac L-type Ca²⁺ channel activity induces hypertrophy and heart failure in mice.

Donald M Bers, Steven R Houser, Franz Hofmann, 2012, The Journal of clinical investigation.

Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle.

R. Hajjar, J. Molkentin, E. Kranias, 2011, The Journal of clinical investigation.

Identification of Cysteines Involved in S-Nitrosylation, S-Glutathionylation, and Oxidation to Disulfides in Ryanodine Receptor Type 1*

S. Hamilton, C. Hidalgo, R. Dirksen, 2006, Journal of Biological Chemistry.

Na Dysregulation Coupled with Ca 2 (cid:2) Entry through NCX1 Promotes Muscular Dystrophy in Mice

D. Millay, K. Philipson, Jose R. Lopez, 2014 .