A. Middleton

发表

The molecular basis of lysine 48 ubiquitin chain synthesis by Ube2K

C. Day, A. Middleton, 2015, Scientific Reports.

The structure and ubiquitin binding properties of TRAF RING heterodimers.

C. Day, P. Mace, E. Ledgerwood, 2021, Journal of molecular biology.

How Effective is Distance Education

Ada J. Middleton, A. Middleton, 1997 .

The RING Domain of RING Finger 12 Efficiently Builds Degradative Ubiquitin Chains.

C. Day, J. Zhu, A. Middleton, 2020, Journal of molecular biology.

Expression and characterization of an antifreeze protein from the perennial rye grass, Lolium perenne.

Alan Brown, P. Davies, K. Lauersen, 2011, Cryobiology.

Identification of Ubiquitin Variants That Inhibit the E2 Ubiquitin Conjugating Enzyme, Ube2k.

J. Teyra, S. Sidhu, C. Day, 2021, ACS chemical biology.

Identification of ubiquitin variants that inhibit the E2 ubiquitin conjugating enzyme, Ube2k

J. Teyra, S. Sidhu, C. Day, 2021, bioRxiv.

Isolation and Characterization of Ice-Binding Proteins from Higher Plants.

P. Davies, V. Walker, L. Graham, 2020, Methods in molecular biology.

Isolation and characterization of ice-binding proteins from higher plants.

P. Davies, V. Walker, A. Middleton, 2014, Methods in molecular biology.

Ice restructuring inhibition activities in antifreeze proteins with distinct differences in thermal hysteresis.

Alan Brown, P. Davies, V. Walker, 2010, Cryobiology.

Identification of the ice‐binding face of a plant antifreeze protein

P. Davies, V. Walker, A. Middleton, 2009, FEBS letters.

Ubiquitin Variant Inhibitors Meet the Deubiquitinase USP15.

C. Day, A. Middleton, 2019, Structure.

Antifreeze protein from freeze-tolerant grass has a beta-roll fold with an irregularly structured ice-binding site.

Christopher B. Marshall, Virginia K. Walker, Robert L. Campbell, 2012, Journal of molecular biology.

The activity of TRAF RING homo- and heterodimers is regulated by zinc finger 1

C. Day, P. Mace, A. Middleton, 2017, Nature Communications.

Use of E2~ubiquitin conjugates for the characterization of ubiquitin transfer by RING E3 ligases such as the inhibitor of apoptosis proteins.

C. Day, A. Middleton, Rhesa Budhidarmo, 2014, Methods in enzymology.

A bidentate Polycomb Repressive-Deubiquitinase complex is required for efficient activity on nucleosomes

R. Dobson, C. Day, P. Mace, 2018, Nature Communications.

Compound ice-binding site of an antifreeze protein revealed by mutagenesis and fluorescent tagging.

P. Davies, I. Braslavsky, M. Kuiper, 2010, Biochemistry.

Regulation of E2s: A Role for Additional Ubiquitin Binding Sites?

C. Day, A. Middleton, Joshua D. Wright, 2017, Journal of molecular biology.

From seeds to trees: how E2 enzymes grow ubiquitin chains

C. Day, A. Middleton, 2023, Biochemical Society transactions.

Ubiquitin and a charged loop regulate the ubiquitin E3 ligase activity of Ark2C

C. Day, P. Mace, C. Rossig, 2022, Nature Communications.

Structural insights into K48-linked ubiquitin chain formation by the Pex4p-Pex22p complex.

S. Marrink, C. Schroer, M. Groves, 2017, Biochemical and biophysical research communications.

Structural insights into K48-linked ubiquitin chain formation by the Pex4p-Pex22p complex.

S. Marrink, C. Schroer, M. Groves, 2017, Biochemical and biophysical research communications.

Structure and Function of the RING Domains of RNF20 and RNF40, Dimeric E3 Ligases that Monoubiquitylate Histone H2B.

C. Day, A. Middleton, Martina Foglizzo, 2016, Journal of molecular biology.

Zinc finger 1 of the RING E3 ligase, RNF125, interacts with the E2 to enhance ubiquitylation.

C. Day, A. Middleton, Khanh Nguyen, 2023, Structure.

A bidentate Polycomb Repressive-Deubiquitinase complex is required for efficient activity on nucleosomes

R. Dobson, C. Day, P. Mace, 2018, Nature Communications.

Regulation of E2s: A Role for Additional Ubiquitin Binding Sites?

C. Day, A. Middleton, Joshua D. Wright, 2017, Journal of molecular biology.

Antifreeze protein from freeze-tolerant grass has a beta-roll fold with an irregularly structured ice-binding site.

R. Campbell, P. Davies, F. Faucher, 2012, Journal of molecular biology.

Engineered Ubiquitin Variants Mitigate Pathogenic Bacterial Ubiquitin Ligase Function

A. Middleton, Bradley E. Dubrule, Sachdev S. Sidhu, 2024, bioRxiv.