S. Zech

发表

When are two waters worse than one? Doubling the hydration number of a Gd-DTPA derivative decreases relaxivity.

Peter Caravan, Normand J. Cloutier, M. Spiller, 2005, Chemistry.

Jindong Zhao, D. Bryant, R. Bittl, 2002, The Journal of Biological Chemistry.

Electron Transfer in Cyanobacterial Photosystem I

B. Zybailov, R. Bittl, G. Shen, 2003, Journal of Biological Chemistry.

Electron Transfer in Cyanobacterial Photosystem I I. PHYSIOLOGICAL AND SPECTROSCOPIC CHARACTERIZATION OF SITE-DIRECTED MUTANTS IN A PUTATIVE ELECTRON TRANSFER PATHWAY FROM A 0 THROUGH A 1 TO F X

B. Zybailov, R. Bittl, G. Shen, 2003 .

Recruitment of a Foreign Quinone into the A1 Site of Photosystem I

B. Zybailov, A. D. Jones, R. Bittl, 2001, The Journal of Biological Chemistry.

Insertional inactivation of the menG gene, encoding 2-phytyl-1,4-naphthoquinone methyltransferase of Synechocystis sp. PCC 6803, results in the incorporation of 2-phytyl-1,4-naphthoquinone into the A(1) site and alteration of the equilibrium constant between A(1) and F(X) in photosystem I.

B. Zybailov, A. D. Jones, D. Bryant, 2002, Biochemistry.

Addressing Atropisomerism in the Development of Sotorasib, a Covalent Inhibitor of KRAS G12C: Structural, Analytical, and Synthetic Considerations

A. T. Parsons, S. Zech, B. Lanman, 2022, Accounts of chemical research.

Discovery of a covalent inhibitor of KRASG12C (AMG 510) for the treatment of solid tumors.

N. Chen, J. McCarter, K. Rex, 2019, Journal of medicinal chemistry.

EP-2104R: a fibrin-specific gadolinium-Based MRI contrast agent for detection of thrombus.

Peter Caravan, P. Caravan, T. McMurry, 2008, Journal of the American Chemical Society.

Pulsed EPR measurement of the distance between P680 +· and QA −· in photosystem II

W. Lubitz, G. Renger, R. Bittl, 1997, FEBS letters.

Protein structure determination by high-resolution solid-state NMR spectroscopy: application to microcrystalline ubiquitin.

A. Wand, A. McDermott, S. Zech, 2005, Journal of the American Chemical Society.

Mobocertinib (TAK-788): A Targeted Inhibitor of EGFR Exon 20 Insertion Mutants in Non-Small Cell Lung Cancer.

Kwok-Kin Wong, T. Clackson, A. Gould, 2021, Cancer discovery.

Fragment growing and linking lead to novel nanomolar lactate dehydrogenase inhibitors.

T. Clackson, V. Rivera, T. Zhou, 2013, Journal of medicinal chemistry.

Discovery of Mobocertinib, a Potent, Oral Inhibitor of EGFR Exon 20 Insertion Mutations in Non-Small Cell Lung Cancer.

T. Clackson, A. Gould, V. Rivera, 2022, Bioorganic & medicinal chemistry letters.

Electron paramagnetic resonance studies of zinc-substituted reaction centers from Rhodopseudomonas viridis.

W. Lubitz, A. Gardiner, E. Schlodder, 1999, Biochemistry.

Pulsed EPR Study of Spin-Coupled Radical Pairs in Photosynthetic Reaction Centers: Measurement of the Distance Between and in Photosystem I and between and in Bacterial Reaction Centers

R. Bittl, S. Zech, 1997 .

Electron Transfer in Cyanobacterial Photosystem I

B. Zybailov, G. Shen, J. Golbeck, 2003, Journal of Biological Chemistry.

Novel Small Molecule Inhibitors of Choline Kinase Identified by Fragment-Based Drug Discovery.

T. Zhou, M. Greenfield, J. Miret, 2016, Journal of medicinal chemistry.

Pulsed EPR spectroscopy on short-lived intermediates in Photosystem I.

R. Bittl, S. Zech, 2001, Biochimica et biophysica acta.

High-frequency EPR studies on cofactor radicals in photosystem I

W. Lubitz, R. Bittl, W. Hofbauer, 2001 .

Recruitment of a foreign quinone into the A(1) site of photosystem I. II. Structural and functional characterization of phylloquinone biosynthetic pathway mutants by electron paramagnetic resonance and electron-nuclear double resonance spectroscopy.

B. Zybailov, R. Bittl, G. Shen, 2000, The Journal of biological chemistry.

The Radical Pair State in Photosystem I Single Crystals: Orientation Dependence of the Transient Spin-Polarized EPR Spectra

P. Fromme, W. Lubitz, H. Witt, 1998 .

The Quinone Acceptor A1 in Photosystem I: Binding Site, and Comparison to QA in Purple Bacteria Reaction Centers

P. Fromme, W. Lubitz, R. Bittl, 1998 .

Transient and pulsed EPR spectroscopy on the radical pair state P865+.QA−. to study light-induced changes in bacterial reaction centers

W. Lubitz, A. Gardiner, R. Bittl, 1997 .

Pulsed EPR structure analysis of photosystem I single crystals: localization of the phylloquinone acceptor.

P. Fromme, W. Lubitz, H. Witt, 1997, Biochemistry.

Measurement of cofactor distances between P700.+ and A1.- in native and quinone-substituted photosystem I using pulsed electron paramagnetic resonance spectroscopy.

R. Bittl, S. Zech, A. van der Est, 1997, Biochemistry.

Pulsed EPR experiments on radical pairs in photosynthesis: Comparison of the donor‐acceptor distances in photosystem I and bacterial reaction centers

W. Lubitz, R. Bittl, S. Zech, 1996 .

Determination of the distance between Yox⋅ Z and Q−⋅ A in photosystem II by pulsed EPR spectroscopy on light‐induced radical pairs

W. Lubitz, R. Bittl, J. Kurreck, 1999, FEBS letters.

Determination of the hydration number of gadolinium(III) complexes by high-field pulsed 17O ENDOR spectroscopy.

Peter Caravan, O. Poluektov, P. Caravan, 2006, Chemphyschem : a European journal of chemical physics and physical chemistry.

Orientation and Protein−Cofactor Interactions of Monosubstituted n-Alkyl Naphthoquinones in the A1 Binding Site of Photosystem I

Sarah L. Brown, H. Zimmermann, Y. Pushkar, 2002 .

Ionic states of substrates and transition state analogues at the catalytic sites of N-ribosyltransferases.

G. Evans, R. Furneaux, V. Schramm, 2003, Biochemistry.

Structural Information on Components of the Electron Transfer Chain in Photosystem I From Time-Resolved EPR Spectroscopy

W. Lubitz, L. Krabben, R. Bittl, 1998 .

Light induced radical pair intermediates in photosynthetic reaction centres in contact with an observer spin label: spin dynamics and effects on transient EPR spectra

K. Salikhov, D. Stehlik, S. Zech, 2002 .

A structural model for the charge separated state P700̇+A1̇+ photosystem I from the orientation of the magnetic interaction tensors

P. Fromme, W. Lubitz, R. Bittl, 2000 .

Abstract 2644: AP32788, a potent, selective inhibitor of EGFR and HER2 oncogenic mutants, including exon 20 insertions, in preclinical models

V. Rivera, T. Zhou, M. Greenfield, 2016 .

Electron Paramagnetic Resonance Studies of Zinc-Substituted Reaction Centers from Rhodopseudomonas V iridis †

W. Lubitz, A. Gardiner, E. Schlodder, 1999 .

Probing the water coordination of protein-targeted MRI contrast agents by pulsed ENDOR spectroscopy.

Peter Caravan, Wei-Chuan Sun, V. Jacques, 2005, Chemphyschem : a European journal of chemical physics and physical chemistry.

Protein binding to lanthanide(III) complexes can reduce the water exchange rate at the lanthanide.

Peter Caravan, P. Caravan, Mark P Lowe, 2007, Inorganic chemistry.