P. Borysko

发表

A prospective compound screening contest identified broader inhibitors for Sirtuin 1

Shogo D. Suzuki, Hironori K. Nakamura, Kazuki Z. Yamamoto, 2019, Scientific Reports.

Screening of benzenesulfonamide in combination with chemically diverse fragments against carbonic anhydrase by differential scanning fluorimetry

C. Supuran, A. Angeli, S. Zozulya, 2019, Journal of enzyme inhibition and medicinal chemistry.

Straightforward hit identification approach in fragment-based discovery of bromodomain-containing protein 4 (BRD4) inhibitors.

Yurii S. Moroz, V. Hurmach, S. Zozulya, 2018, Bioorganic & Medicinal Chemistry.

Synthesis of Multifunctional Spirocyclic Azetidines and Their Application in Drug Discovery.

S. Zozulya, Pavel K. Mykhailiuk, V. Kubyshkin, 2018, Chemistry.

Anionic amphiphilic calixarenes for peptide assembly and delivery.

Y. Mély, R. Rodik, V. Kalchenko, 2022, Journal of colloid and interface science.

Difluoromethyl Nitrile Oxide (CF2HCNO): A Neglected Chemical Reagent

Pavel K. Mykhailiuk, P. Borysko, Bohdan A. Chalyk, 2017 .

In Vitro Evaluation of In Silico Screening Approaches in Search for Selective ACE2 Binding Chemical Probes

D. Horvath, A. Varnek, O. Klimchuk, 2022, Molecules.

Towards in vivo photomediated delivery of anticancer peptides: Insights from pharmacokinetic and -dynamic data.

A. Ulrich, S. Afonin, O. Babii, 2022, Journal of photochemistry and photobiology. B, Biology.

Magnet for the Needle in Haystack: "Crystal Structure First" Fragment Hits Unlock Active Chemical Matter Using Targeted Exploration of Vast Chemical Spaces.

Yurii S. Moroz, G. Klebe, M. Gastreich, 2022, Journal of medicinal chemistry.

Photochemical Synthesis of 2-Azabicyclo[3.2.0]heptanes: Advanced Building Blocks for Drug Discovery. Synthesis of 2,3-Ethanoproline.

S. Zozulya, Pavel K. Mykhailiuk, P. Borysko, 2018, The Journal of organic chemistry.

Phosphine Oxides (-POMe2) for Medicinal Chemistry: Synthesis, Properties, and Applications.

H. Kuznietsova, Pavel K. Mykhailiuk, P. Borysko, 2021, The Journal of organic chemistry.

Oxa-spirocycles: synthesis, properties and applications

H. Kuznietsova, Pavel K. Mykhailiuk, P. Borysko, 2021, Chemical science.

An iterative compound screening contest method for identifying target protein inhibitors using the tyrosine-protein kinase Yes

Daisuke Kihara, Takashi Ishida, Masakazu Sekijima, 2017, Scientific Reports.

Photochemical In-Flow Synthesis of 2,4-Methanopyrrolidines: Pyrrolidine Analogues with Improved Water Solubility and Reduced Lipophilicity.

A. Tolmachev, S. Zozulya, Oleg M. Michurin, 2018, The Journal of organic chemistry.

(Chlorosulfonyl)benzenesulfonyl Fluorides-Versatile Building Blocks for Combinatorial Chemistry: Design, Synthesis and Evaluation of a Covalent Inhibitor Library.

Yurii S. Moroz, M. Platonov, S. Zozulya, 2018, ACS combinatorial science.

SAR by Space: Enriching Hit Sets from the Chemical Space

Christian Lemmen, Franca-Maria Klingler, Marcus Gastreich, 2019, Molecules.

Pros and cons of virtual screening based on public "Big Data": In silico mining for new bromodomain inhibitors.

Jürgen Bajorath, Dragos Horvath, Alexandre Varnek, 2019, European journal of medicinal chemistry.

Effect of gem-difluorination on the key physicochemical properties relevant to medicinal chemistry: the case of functionalized cycloalkanes.

O. Grygorenko, D. Volochnyuk, S. Ryabukhin, 2022, Chemistry.

The iterative application of a large chemical space in the drug discovery process

Yurii S. Moroz, Dmytro V. Dudenko, Igor Dziuba, 2021, Journal of Organic and Pharmaceutical Chemistry.

Continued SAR exploration of 1,2,4-thiadiazole-containing scaffolds in the design of free fatty acid receptor 1 (GPR40) agonists.

I. Tikhonova, S. Zozulya, O. Onopchenko, 2017, European journal of medicinal chemistry.

An iterative compound screening contest method for identifying target protein inhibitors using the tyrosine-protein kinase Yes

Shogo D. Suzuki, Kazuki Z. Yamamoto, D. Kihara, 2017, Scientific Reports.

Further validation of strecker-type α-aminonitriles as a new class of potent human carbonic anhydrase II inhibitors: hit expansion within the public domain using differential scanning fluorimetry leads to chemotype refinement

C. Supuran, A. Angeli, S. Zozulya, 2019, Journal of enzyme inhibition and medicinal chemistry.

Discovery of Strecker-type α-aminonitriles as a new class of human carbonic anhydrase inhibitors using differential scanning fluorimetry

C. Supuran, D. Vullo, S. Zozulya, 2016, Journal of enzyme inhibition and medicinal chemistry.