N. Ninkina

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Peripheral sensory neurons survive in the absence of α- and γ-synucleins

V. Buchman, N. V. Gnuchev, Katerina K Papachroni, 2007, Journal of Molecular Neuroscience.

Triple-Knockout, Synuclein-Free Mice Display Compromised Lipid Pattern

I. Guschina, V. Buchman, N. Ninkina, 2021, Molecules.

Mutations in the gene encoding human persyn are not associated with amyotrophic lateral sclerosis or familial Parkinson's disease

J. Powell, P. Leigh, N. Wood, 1999, Neuroscience Letters.

Dimebon Does Not Ameliorate Pathological Changes Caused by Expression of Truncated (1–120) Human Alpha-Synuclein in Dopaminergic Neurons of Transgenic Mice

M. Spillantini, V. Buchman, O. Peters, 2011, Neurodegenerative Diseases.

Edinburgh Research Explorer Absence of alpha-synuclein affects dopamine metabolism and synaptic markers in the striatum of aging mice

V. Buchman, P. Jones, N. Ninkina, 2010 .

Intracellular Compartmentalization of Two Differentially Spliceds-rex/NSPmRNAs in Neurons

A. Davies, V. Buchman, N. Ninkina, 1996, Molecular and Cellular Neuroscience.

Cerd4, third member of the d4 gene family: expression and organization of genomic locus

V. Buchman, D. Kulikova, O. Simonova, 2001, Mammalian Genome.

Structure and expression of two members of the d4 gene family in mouse

V. Buchman, D. Kulikova, N. Ninkina, 2000, Mammalian Genome.

γ-Synucleinopathy: neurodegeneration associated with overexpression of the mouse protein

V. Buchman, O. Peters, H. van der Putten, 2009, Human molecular genetics.

A variation in the structure of the protein-coding region of the human p53 gene.

P. Chumakov, V. Buchman, G. Georgiev, 1988, Gene.

Selective pattern of motor system damage in gamma-synuclein transgenic mice mirrors the respective pathology in amyotrophic lateral sclerosis

V. Buchman, I. Soto, O. Peters, 2012, Neurobiology of Disease.

β-synuclein potentiates synaptic vesicle dopamine uptake and rescues dopaminergic neurons from MPTP-induced death in the absence of other synucleins

V. Buchman, D. Withers, O. Peters, 2021, The Journal of biological chemistry.

Monomeric Alpha-Synuclein Exerts a Physiological Role on Brain ATP Synthase

V. Buchman, S. Gandhi, A. Abramov, 2016, The Journal of Neuroscience.

Contrasting Effects of α-Synuclein and γ-Synuclein on the Phenotype of Cysteine String Protein α (CSPα) Null Mutant Mice Suggest Distinct Function of these Proteins in Neuronal Synapses*

V. Buchman, O. Peters, Natalie Connor-Robson, 2012, The Journal of Biological Chemistry.

Localization of Synucleins in the Mammalian Cochlea

V. Buchman, O. Akil, L. Lustig, 2008, Journal of the Association for Research in Otolaryngology.

Combinational losses of synucleins reveal their differential requirements for compensating age-dependent alterations in motor behavior and dopamine metabolism

V. Buchman, O. Peters, Natalie Connor-Robson, 2016, Neurobiology of Aging.

Targeted Inactivation of the Gene Encoding Gamma-Synuclein Affects Anxiety Levels and Investigative Activity in Mice

V. Buchman, T. Strekalova, S. Bachurin, 2012, Neuroscience and Behavioral Physiology.

Chronic administration of Dimebon does not ameliorate amyloid-β pathology in 5xFAD transgenic mice.

V. Buchman, O. Peters, S. Brooks, 2013, Journal of Alzheimer's disease : JAD.

Contents Vol. 8, 2011

Jane S. Paulsen, Robert P. Davis, J. L. Mesa, 2011, Neurodegenerative Diseases.

Methylene blue and dimebon inhibit aggregation of TDP‐43 in cellular models

M. Goedert, H. Akiyama, F. Kametani, 2009, FEBS letters.

Hindering of proteinopathy-induced neurodegeneration as a new mechanism of action for neuroprotectors and cognition enhancing compounds

V. Buchman, O. Peters, S. Bachurin, 2009, Doklady Biochemistry and Biophysics.

[New aspects of the pathogenesis of lateral amyotrophic sclerosis].

A. P. Smirnov, S. Bachurin, E. A. Kovrazhkina, 2011, Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova.

GFRα-4 and the tyrosine kinase Ret form a functional receptor complex for persephin

A. Davies, V. Buchman, F. Sauvage, 1998, Current Biology.

Stem cell therapy and FUS[1‐359]‐transgenic mice: A recent study highlighting a promising ALS model and a promising therapy

N. Ninkina, 2020, CNS neuroscience & therapeutics.

[A mice model of amyotrophic lateral sclerosis expressing mutant human FUS protein].

A. P. Smirnov, V. Skvortsova, S. Bachurin, 2014, Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova.

Behavioural impairments in mice of a novel FUS transgenic line recapitulate features of frontotemporal lobar degeneration

V. Buchman, A. Deykin, M. Kukharsky, 2019, Genes, brain, and behavior.

Fused in Sarcoma (FUS) Protein Lacking Nuclear Localization Signal (NLS) and Major RNA Binding Motifs Triggers Proteinopathy and Severe Motor Phenotype in Transgenic Mice

V. Buchman, O. Peters, A. Deykin, 2013, The Journal of Biological Chemistry.

Increased lipolysis and altered lipid homeostasis protect γ-synuclein–null mutant mice from diet-induced obesity

I. Guschina, V. Buchman, S. Adams, 2012, Proceedings of the National Academy of Sciences.

Synuclein Deficiency Decreases the Efficiency of Dopamine Uptake by Synaptic Vesicles

V. Buchman, S. Bachurin, N. Ninkina, 2019, Doklady Biochemistry and Biophysics.

Early lethality and neuronal proteinopathy in mice expressing cytoplasm-targeted FUS that lacks the RNA recognition motif

V. Buchman, A. Deykin, S. Bachurin, 2015, Amyotrophic lateral sclerosis & frontotemporal degeneration.

Phenotype in Transgenic Mice Proteinopathy and Severe Motor Major RNA Binding Motifs Triggers Nuclear Localization Signal ( NLS ) and Fused in Sarcoma ( FUS ) Protein Lacking Molecular Bases of Disease :

V. Buchman, O. Peters, A. Deykin, 2013 .

Compromised paraspeckle formation as a pathogenic factor in FUSopathies

C. Troakes, V. Buchman, T. Shelkovnikova, 2013, Human molecular genetics.

Autoantibodies to alpha‐synuclein in inherited Parkinson’s disease

V. Buchman, G. Hadjigeorgiou, G. Xiromerisiou, 2006, Journal of neurochemistry.

β-synuclein promotes synaptic vesicle dopamine uptake and rescues dopaminergic neurons from MPTP-induced death

V. Buchman, D. Withers, O. Peters, 2020 .

Simultaneous and independent detection of C9ORF72 alleles with low and high number of GGGGCC repeats using an optimised protocol of Southern blot hybridisation

A. Higginbottom, V. Buchman, J. Kirby, 2013, Molecular Neurodegeneration.

Gamma-synuclein pathology in amyotrophic lateral sclerosis

T. Hortobágyi, C. Troakes, J. Highley, 2014, Annals of clinical and translational neurology.

FUS gene mutations associated with familiar forms of amyotrophic lateral sclerosis affect cellular localization and aggregation properties of the encoded protein

A. P. Smirnov, V. Buchman, S. Bachurin, 2011, Doklady Biochemistry and Biophysics.

Effects of ALS-associated mutations on the in vivo aggregation and toxicity of human FUS/TLS protein

V. Buchman, S. Bachurin, T. Shelkovnikova, 2009 .

C9ORF72 hexanucleotide repeat expansion in ALS patients from the Central European Russia population

M. Stepanova, V. Skvortsova, V. Buchman, 2015, Neurobiology of Aging.

C9ORF72 transcription in a frontotemporal dementia case with two expanded alleles

A. Higginbottom, V. Buchman, J. Kirby, 2013, Neurology.

Study into possible molecular targets of a neuroprotective compound dimebon using a transgenic mouse line

S. Bachurin, A. Ustyugov, T. Shelkovnikova, 2013, Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry.

Oscillation processes in synuclein-KO mouse skin microcirculation: a pilot study

A. Tankanag, A. Dunaev, D. Serov, 2022, Saratov Fall Meeting.

Multiple domains of Ruk/CIN85/SETA/CD2BP3 are involved in interaction with p85alpha regulatory subunit of PI 3-kinase.

L. B. Drobot, Yaroslav Fedyshyn, V. Buchman, 2004, Journal of molecular biology.

Organization of the mouse Ruk locus and expression of isoforms in mouse tissues.

I. Gout, V. Buchman, N. Ninkina, 2002, Gene.

Increased striatal dopamine release and hyperdopaminergic‐like behaviour in mice lacking both alpha‐synuclein and gamma‐synuclein

S. Cragg, D. Bannerman, V. Buchman, 2008, The European journal of neuroscience.

N. Sarycheva, N. Ninkina, I. Shamakina, 2022, Biomedicines.

Targeted Inactivation of the Gene Encoding Gamma-Synuclein Affects Anxiety Levels and Investigative Activity in Mice

V. Buchman, T. Strekalova, S. Bachurin, 2012, Neuroscience and Behavioral Physiology.

[Isolation and characteristics of clones complementary to mRNA of the murine cellular tumor antigen p53].

P. Chumakov, V. Iotsova, G. Georgiev, 1988, Genetika.

Therapeutic effect of exogenous hsp70 in mouse models of Alzheimer's disease.

E. Nudler, M. Evgen’ev, V. Karpov, 2013, Journal of Alzheimer's disease : JAD.

Molecular cloning and expression pattern of rpr‐1, a resiniferatoxin‐binding, phosphotriesterase‐related protein, expressed in rat kidney tubules 1

J. Davies, V. Buchman, N. Ninkina, 1997, FEBS letters.

Long non-coding RNA Neat1 regulates adaptive behavioural response to stress in mice

Wenbin Wei, V. Buchman, S. Nakagawa, 2019, bioRxiv.

Negative regulation of PI 3‐kinase by Ruk, a novel adaptor protein

L. B. Drobot, I. Gout, M. Waterfield, 2000, The EMBO journal.

Hunk/Mak-v is a negative regulator of intestinal cell proliferation

A. Clarke, V. Buchman, E. Korobko, 2015, BMC Cancer.

Hunk/Mak-v is a negative regulator of intestinal cell proliferation

A. Clarke, V. Buchman, Ben R. Hopkins, 2015, BMC Cancer.

Neurons Expressing the Highest Levels of γ-Synuclein Are Unaffected by Targeted Inactivation of the Gene

A. Davies, V. Buchman, F. Court, 2003, Molecular and Cellular Biology.

TrkB Variants with Deletions in the Leucine-rich Motifs of the Extracellular Domain*

A. Davies, V. Buchman, N. Ninkina, 1997, The Journal of Biological Chemistry.

Induction of neuronal death by α‐synuclein

A. Davies, D. Hanger, V. Buchman, 2000, The European journal of neuroscience.

Multistep process of FUS aggregation in the cell cytoplasm involves RNA-dependent and RNA-independent mechanisms

V. Buchman, T. Shelkovnikova, N. Ninkina, 2014, Human molecular genetics.

Whole genome expression analyses of single- and double-knock-out mice implicate partially overlapping functions of alpha- and gamma-synuclein

S. Poths, O. Riess, M. Bonin, 2007, Neurogenetics.

γ-synuclein is a novel player in the control of body lipid metabolism

V. Buchman, J. Rochford, N. Ninkina, 2013, Adipocyte.

Stem cells in human breast milk

V. Buchman, A. Deykin, M. Kukharsky, 2019, Human Cell.

Zinc Induces Temperature-Dependent Reversible Self-Assembly of Tau.

P. Tsvetkov, D. Byrne, V. Peyrot, 2019, Journal of molecular biology.

Induction of de novo α-synuclein fibrillization in a neuronal model for Parkinson’s disease

E. Masliah, H. Lashuel, E. Rockenstein, 2016, Proceedings of the National Academy of Sciences.

A novel resource for studying function and dysfunction of α-synuclein: mouse lines for modulation of endogenous Snca gene expression

V. Buchman, Natalie Connor-Robson, A. Ustyugov, 2015, Scientific Reports.

Endogenous alpha-synuclein influences the number of dopaminergic neurons in mouse substantia nigra

J. Dalley, M. Spillantini, V. Buchman, 2013, Experimental Neurology.

Modulation of α-synuclein expression in transgenic animals for modelling synucleinopathies — is the juice worth the squeeze?

V. Buchman, N. Ninkina, 2008, Neurotoxicity Research.

Persyn, a Member of the Synuclein Family, Has a Distinct Pattern of Expression in the Developing Nervous System

A. Davies, V. Buchman, N. Ninkina, 1998, The Journal of Neuroscience.

Role of synucleins in traumatic brain injury — An experimental in vitro and in vivo study in mice

Shuangteng He, P. Stahel, A. Surguchov, 2014, Molecular and Cellular Neuroscience.

Functional Alterations to the Nigrostriatal System in Mice Lacking All Three Members of the Synuclein Family

Richard Wade-Martins, J. Paul Bolam, David M. Bannerman, 2011, The Journal of Neuroscience.

Developmental loss and resistance to MPTP toxicity of dopaminergic neurones in substantia nigra pars compacta of γ‐synuclein, α‐synuclein and double α/γ‐synuclein null mutant mice

John Sharkey, Paul A. Jones, V. Buchman, 2004 .

Developmental loss and resistance to MPTP toxicity of dopaminergic neurones in substantia nigra pars compacta of gamma-synuclein, alpha-synuclein and double alpha/gamma-synuclein null mutant mice.

V. Buchman, P. Jones, J. Sharkey, 2004, Journal of neurochemistry.

Chronic administration of dimebon ameliorates pathology in TauP301S transgenic mice.

V. Buchman, O. Peters, S. Bachurin, 2013, Journal of Alzheimer's disease : JAD.

Dimebon Reduces the Levels of Aggregated Amyloidogenic Protein Forms in Detergent-Insoluble Fractions In Vivo

V. Buchman, O. Peters, S. Bachurin, 2012, Bulletin of Experimental Biology and Medicine.

Dimebon Slows Progression of Proteinopathy in γ-Synuclein Transgenic Mice

V. Buchman, O. Peters, S. Bachurin, 2011, Neurotoxicity Research.

Triple-Knockout, Synuclein-Free Mice Display Compromised Lipid Pattern

I. Guschina, V. Buchman, N. Ninkina, 2020, Molecules.

Lipid Classes and Fatty Acid Patterns are Altered in the Brain of γ-Synuclein Null Mutant Mice

J. Harwood, I. Guschina, V. Buchman, 2010, Lipids.

Zinc binding to RNA recognition motif of TDP-43 induces the formation of amyloid-like aggregates

P. Tsvetkov, D. Byrne, R. Lebrun, 2017, Scientific Reports.

Protein Aggregation in Retinal Cells and Approaches to Cell Protection

Andrei Surguchov, K. Grasing, V. Buchman, 2005, Cellular and Molecular Neurobiology.

A bioisostere of Dimebon/Latrepirdine delays the onset and slows the progression of pathology in FUS transgenic mice

V. Buchman, S. Funikov, Alexander P Rezvykh, 2021, CNS neuroscience & therapeutics.

Control of ventricular excitability by neurons of the dorsal motor nucleus of the vagus nerve

M. Lythgoe, A. Gourine, N. Marina, 2015, Heart rhythm.

Persyn, a member of the synuclein family, influences neurofilament network integrity

Jimi Adu, A. Davies, V. Buchman, 1998, Nature Neuroscience.

γ-Synuclein Is an Adipocyte-Neuron Gene Coordinately Expressed with Leptin and Increased in Human Obesity

K. Clément, V. Buchman, S. Adams, 2008, The Journal of nutrition.

Low Level of Expression of C-Terminally Truncated Human FUS Causes Extensive Changes in the Spinal Cord Transcriptome of Asymptomatic Transgenic Mice

Ilya M. Flyamer, S. Boyle, V. Buchman, 2020, Neurochemical Research.

Low level of expression of C-terminally truncated human FUS causes extensive changes in spinal cord transcriptome of asymptomatic transgenic mice

S. Boyle, V. Buchman, A. Deykin, 2019, bioRxiv.

Alterations in the nigrostriatal system following conditional inactivation of α-synuclein in neurons of adult and aging mice

V. Buchman, M. Kukharsky, A. Durnev, 2020, Neurobiology of Aging.

Proteinopathies, neurodegenerative disorders with protein aggregation-based pathology

P. Tsvetkov, V. Buchman, O. Peters, 2012, Molecular Biology.

Synuclein Deficiency Results in Age-Related Respiratory and Cardiovascular Dysfunctions in Mice

Jeffrey C. Smith, N. Marina, V. Buchman, 2020, Brain sciences.

Simultaneous and independent detection of C9ORF72 alleles with low and high number of GGGGCC repeats using an optimised protocol of Southern blot hybridisation

A. Higginbottom, V. Buchman, J. Kirby, 2013, Molecular Neurodegeneration.

Chicken synucleins: cloning and expression in the developing embryo

A. Davies, D. Hanger, V. Buchman, 2000, Mechanisms of Development.

Low Level of Expression of C-Terminally Truncated Human FUS Causes Extensive Changes in the Spinal Cord Transcriptome of Asymptomatic Transgenic Mice

Ilya M. Flyamer, S. Boyle, V. Buchman, 2020, Neurochemical Research.

Dimebon Slows Progression of Proteinopathy in γ-Synuclein Transgenic Mice

V. Buchman, O. Peters, S. Bachurin, 2011, Neurotoxicity Research.

Dimebon Slows Progression of Proteinopathy in c-Synuclein Transgenic Mice Sergey O. BachurinTatyana A. ShelkovnikovaAlexey A. Ustyugov • Owen PetersIna KhritankovaMarina A. AfanasievaTatyana V. Tarasova • Igor I. AlentovVladimir L. BuchmanNatalia N. Ninkina

Russian Federation., N. Ninkina, V. Tarasova, 2012 .

Gamma-Carbolines Derivatives As Promising Agents for the Development of Pathogenic Therapy for Proteinopathy

V. Buchman, S. Bachurin, V. I. Skvortsova, 2018, Acta naturae.

Peripheral sensory neurons survive in the absence of alpha- and gamma-synucleins.

V. Buchman, N. V. Gnuchev, Katerina K Papachroni, 2005, Journal of molecular neuroscience : MN.

Organization, expression and polymorphism of the human persyn gene.

A. Davies, S. Imreh, V. Buchman, 1998, Human molecular genetics.

Regulation of expression of the neuronal POU protein Oct-2 by nerve growth factor.

D. Latchman, K. Lillycrop, J. Winter, 1992, The Journal of biological chemistry.

Stem cells in human breast milk

V. Buchman, A. Deykin, M. Kukharsky, 2019, Human Cell.

[Modeling of lateral amyotrophic sclerosis: a non-genetic method].

V. Skvortsova, S. Bachurin, E. A. Kovrazhkina, 2013, Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova.

Neurons Expressing the Highest Levels of γ-Synuclein Are Unaffected by Targeted Inactivation of the Gene

A. Davies, V. Buchman, F. Court, 2003, Molecular and Cellular Biology.

Impaired spatial and working memory in ageing mice with targeted inactivation of α-synuclein gene

S. Bachurin, T. Shelkovnikova, N. Ninkina, 2011, Doklady Biological Sciences.

Alterations in the nigrostriatal system following conditional inactivation of α-synuclein in neurons of adult and ageing mice

V. Buchman, A. Ustyugov, N. Ninkina, 2020 .

Absence of α-synuclein affects dopamine metabolism and synaptic markers in the striatum of aging mice☆

V. Buchman, N. Ninkina, Steven J. Millership, 2010, Neurobiology of Aging.

Developmentally regulated expression of persyn, a member of the synuclein family, in skin.

A. Davies, V. Buchman, N. Ninkina, 1999, Experimental cell research.

Proteinopathies, neurodegenerative disorders with protein aggregation-based pathology

P. Tsvetkov, V. Buchman, O. Peters, 2012, Molecular Biology.

Neurons expressing the highest levels of gamma-synuclein are unaffected by targeted inactivation of the gene.

V. Buchman, S. Fleetwood-Walker, Katerina K Papachroni, 2003, Molecular and cellular biology.

Expression and function of TrkB variants in developing sensory neurons.

A. Davies, V. Buchman, A. Fischer, 1996, The EMBO journal.

Detection of autoantibodies to potentially amyloidogenic protein, gamma-synuclein, in the serum of patients with amyotrophic lateral sclerosis and cerebral circulatory disorders

A. Moskovtsev, A. Surguchov, E. A. Kovrazhkina, 2017, Doklady Biochemistry and Biophysics.

Differential splicing creates a diversity of transcripts from a neurospecific developmentally regulated gene encoding a protein with new zinc-finger motifs.

V. Buchman, K. Anokhin, G. Georgiev, 1992, Nucleic acids research.