Kshama A. Doshi

Uncovering Differential Multi-microRNA Signatures of Acute Myeloid and Lymphoblastic Leukemias with a Machine-Learning-Based Network Approach

J. Banavar, W. Losert, C. Civin, 2014 .

The FLT3 and PDGFR inhibitor crenolanib is a substrate of the multidrug resistance protein ABCB1 but does not inhibit transport function at pharmacologically relevant concentrations

S. Ambudkar, S. Shukla, M. Baer, 2015, Investigational New Drugs.

Uncovering low-dimensional, miR-based signatures of acute myeloid and lymphoblastic leukemias with a machine-learning-driven network approach.

J. Banavar, W. Losert, C. Civin, 2014, Convergent science physical oncology.

Pim kinase inhibition sensitizes FLT3-ITD acute myeloid leukemia cells to topoisomerase 2 inhibitors through increased DNA damage and oxidative stress

A. Tron, D. Perrotti, R. Trotta, 2016, Oncotarget.

Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal tandem duplication

A. Chatterjee, J. Hotopp, F. Rassool, 2021, Oncotarget.

Concurrent Inhibition of Pim and FLT3 Kinases Enhances Apoptosis of FLT3-ITD Acute Myeloid Leukemia Cells through Increased Mcl-1 Proteasomal Degradation

A. Tron, D. Perrotti, R. Trotta, 2017, Clinical Cancer Research.

Estimating drug potency in the competitive target mediated drug disposition (TMDD) system when the endogenous ligand is included.

Ho Wa Jacky Cheng, A. Stein, Begum Alaybeyoglu, 2021, Journal of Pharmacokinetics and Pharmacodynamics.

Type-I interferon signaling is essential for robust metronomic chemo-immunogenic tumor regression in murine triple-negative breast cancer

D. Roblyer, D. Waxman, Kshama A. Doshi, 2021, bioRxiv.

Discovery of novel N-hydroxy-2-arylisoindoline-4-carboxamides as potent and selective inhibitors of HDAC11.

Xiaozhang Zheng, Bingsong Han, Pui Yee Ng, 2018, Bioorganic & medicinal chemistry letters.