Y. Aoyagi

发表

Suppressive effect of kamebakaurin on acetaminophen-induced hepatotoxicity by inhibiting lipid peroxidation and inflammatory response in mice

N. Miura, Yong-ri Jin, Y. Adachi, 2017, Pharmacological reports : PR.

Lipase TL®-mediated kinetic resolution of benzoin: facile synthesis of (1R,2S)-erythro-2-amino-1,2-diphenylethanol

Robert M. Williams, N. Agata, Y. Aoyagi, 2000 .

Fluorination of triptolide and its analogues and their cytotoxicity.

T. Matsuzaki, R. Aiyama, Y. Aoyagi, 2008, Bioorganic & medicinal chemistry letters.

Conformational folding of mycobacterial methoxy- and ketomycolic acids facilitated by α-methyl trans-cyclopropane groups rather than cis-cyclopropane units.

D. Minnikin, S. Hirono, H. Gouda, 2013, Microbiology.

Effects of the mammalian lignan, 2,3-dibenzyl-butane-1,4-diol, on contraction and Ca2+ mobilization induced by noradrenaline in rat aorta.

M. Tsuboi, Y. Aoyagi, A. Ohta, 1991, General pharmacology.

Separation and characterization of individual mycolic acids in representative mycobacteria.

D. Minnikin, D E Minnikin, M. Ridell, 2001, Microbiology.

Differential conformational behaviors of alpha-mycolic acids in Langmuir monolayers and computer simulations.

D. Minnikin, S. Hirono, H. Gouda, 2010, Chemistry and physics of lipids.

Salvileucalin C, a novel rearranged neoclerodane diterpene from Salvia leucantha

Nobuaki Miura, K. Monde, Y. Aoyagi, 2011 .

Palladium-catalyzed cross-coupling reactions of chloropyrazines with aromatic heterocycles

A. Inoue, Y. Aoyagi, A. Ohta, 1992 .

Palladium-catalyzed arylation of furan, thiophene, benzo[b]furan and benzo[b]thiophene

Y. Aoyagi, A. Ohta, A. Miyafuji, 1990 .

Synthesis of halohydroxypyrazines and their synthetic utility

Y. Aoyagi, A. Ohta, T. Fujiwara, 1991 .

Facile and Efficient Deoxygenation of Aromatic N-Oxides with Zinc and Aqueous Ammonium Chloride

A. Ohta, Y. Aoyagi, Tomomitsu Abe, 1997 .

Efficient synthesis of novel cytotoxic cis-fused α-methylene γ-lactones from 7,14-dihydroxy-ent-kaurenes by transformation under Mitsunobu reaction conditions

Yongri Jin, Y. Aoyagi, M. Gui, 2004 .

Semisynthesis of Antitrypanosomal p-Quinone Analog Possesing the Komaroviquinone Pharmacophore.

S. Ōmura, T. Matsuzaki, K. Otoguro, 2022, Chemical & pharmaceutical bulletin.

Semisynthesis of salviandulin E analogues and their antitrypanosomal activity.

S. Ōmura, K. Otoguro, H. Yamada, 2014, Bioorganic & medicinal chemistry letters.

Facile and efficient synthesis of pyrroles and indoles via palladium-catalyzed oxidation of hydroxy-enamines and -amines

A. Ohta, Y. Aoyagi, Toshihiko Mizusaki, 1996 .

Lipase TL-mediated kinetic tesolution of 5-benzyloxy-1-tert-butyldimethylsilyloxy-2-pentanol at low temperature: concise asymmetric synthesis of both enantiomers of a piperazic acid derivative.

Robert M. Williams, Tasuku Ueno, Y. Aoyagi, 2003, The Journal of organic chemistry.

Low-valent tantalum-mediated reaction

W. Tanaka, Y. Aoyagi, A. Ohta, 1994 .

Salvileucalin B, a novel diterpenoid with an unprecedented rearranged neoclerodane skeleton from Salvia leucantha Cav.

S. Kawauchi, H. Izumi, Y. Aoyagi, 2008, Organic letters.

Asymmetric synthesis of 1-Boc-3- and 4-hydroxypyrrolidines

Robert M. Williams, Y. Aoyagi, 1998 .

GENERAL ASYMMETRIC SYNTHESIS OF HYDROXYMETHYLENE AND HYDROXYETHYLENE PEPTIDE ISOSTERES

Robert M. Williams, Y. Aoyagi, 1998 .

Samarium(II) diiodide-mediated intermolecular aldol type reactions of phenacyl bromides with carbonyl compounds

H. Tateno, Y. Aoyagi, A. Ohta, 1995 .

Efficient transformation of 7,14-dihydroxy-ent-kaurenes to novel ent-abietanes having cis-fused α-methylene γ-lactones under Mitsunobu reaction conditions and their cytotoxicities

Yongri Jin, Y. Aoyagi, M. Gui, 2014 .

Chromium(II) chloride-mediated coupling reactions of Garner aldehyde with allyl bromides: facile asymmetric synthesis of (2R,3S)-3-hydroxy-2-hydroxymethylpyrrolidine

Y. Aoyagi, A. Ohta, Y. Hiraiwa, 1998 .

Anti-platelet aggregation activity of some pyrazines.

Y. Suwabe, T. Nishio, N. Miyata, 1997, Biological & pharmaceutical bulletin.

Efficient alkylation and acylation of pyrazine 1-oxides

M. Inoue, Y. Aoyagi, A. Ohta, 1991 .

Stereocontrolled asymmetric synthesis of alpha-hydroxy-beta-amino acids. A stereodivergent approach.

R. Williams, Y. Aoyagi, R. Jain, 2001, Journal of the American Chemical Society.

Lipase TL®-mediated kinetic resolution of glycerol analogues: Efficient convergent route to both enantiomeric glycerol units

Robert M. Williams, Y. Aoyagi, K. Takeya, 2021 .

Structures of phenolic glycolipids from Mycobacterium kansasii.

D. Minnikin, Motoko Watanabe, Y. Aoyagi, 1997, European journal of biochemistry.

Three new diterpenoids, tricalysiolide H and tricalysiones A and B, from Tricalysia dubia

T. Kinoshita, Y. Aoyagi, K. Takeya, 2007 .

Tricalysiamides A-D, diterpenoid alkaloids from Tricalysia dubia.

T. Kinoshita, Y. Aoyagi, K. Takeya, 2007, Journal of natural products.

Biomimetic synthesis of grandione from demethylsalvicanol via hetero-Diels–Alder type dimerization and structure revision of grandione

T. Matsuzaki, R. Aiyama, Y. Aoyagi, 2005 .

Semisynthesis of isetexane diterpenoid analogues and their cytotoxic activity.

T. Matsuzaki, R. Aiyama, Y. Aoyagi, 2006, Chemical & pharmaceutical bulletin.

Cytotoxicity of abietane diterpenoids from Perovskia abrotanoides and of their semisynthetic analogues.

T. Matsuzaki, R. Aiyama, Y. Aoyagi, 2006, Bioorganic & medicinal chemistry.

Asymmetric Synthesis of [2,3-13C2,15N]-4-Benzyloxy-5,6-diphenyl-2,3,5,6-tetrahydro-4H-oxazine-2-one via Lipase TL-Mediated Kinetic Resolution of Benzoin: General Procedure for the Synthesis of [2,3-13C2,15N]-l-Alanine

Robert M. Williams, Y. Aoyagi, A. Iijima, 2001 .

Cytotoxic Bisnor- and Norditerpene Dilactones Having 7α,8α-Epoxy-9,11-enolide Substructure from Podocarpus macrophyllus D. D ON

T. Koyama, T. Akiyama, Y. Aoyagi, 2009 .

Rakanmakilactones A–F, new cytotoxic sulfur-containing norditerpene dilactones from leaves of Podocarpus macrophyllus var. maki

Y. Aoyagi, K. Takeya, H. Fukaya, 2004 .

Cytotoxic Bisnor- and Norditerpene Dilactones Having 7α,8α-Epoxy-9,11-enolide Substructure from Podocarpus macrophyllus D. Don.

T. Koyama, T. Akiyama, Y. Aoyagi, 2009 .

New cytotoxic norditerpene dilactones from leaves of Podocarpus macrophyllus var. maki

Y. Aoyagi, K. Takeya, H. Fukaya, 2004 .

S(R)-podolactone D, a new sulfoxide-containing norditerpene dilactone from Podocarpus macrophyllus var. maki.

Y. Aoyagi, K. Takeya, H. Fukaya, 2003, Journal of natural products.

New cytotoxic nor- and bisnorditerpene dilactones, makilactones A-D, from Podocarpus macrophyllus D. Don

T. Koyama, T. Akiyama, Y. Aoyagi, 2009 .

Antibacterial novel phenolic diterpenes from Podocarpus macrophyllus D. Don.

T. Koyama, T. Akiyama, Y. Aoyagi, 2008, Chemical & pharmaceutical bulletin.

Rakanmakilactones A—F, New Cytotoxic Sulfur‐Containing Norditerpene Dilactones from Leaves of Podocarpus macrophyllus var. maki.

Y. Aoyagi, K. Takeya, H. Fukaya, 2004 .

First total synthesis of pyrrolam A

A. Ohta, Y. Aoyagi, T. Kurihara, 1996 .

SYNTHESIS OF EGONOL AND ()-MACHICENDIOL

Y. Aoyagi, A. Ohta, Toshihiko Mizusaki, 1995 .

Protection from acetaminophen-induced hepatotoxicity by post-administration of 1O, 20O-diacetyl kamebakaurin in mice

N. Miura, Yong-ri Jin, Y. Adachi, 2018, Fundamental Toxicological Sciences.

Palladium‐Catalyzed Cross‐Coupling Reactions of Chloropyrazines with Aromatic Heterocycles.

A. Inoue, Y. Aoyagi, A. Ohta, 1992 .

First total synthesis of (±)-oxerine

Y. Aoyagi, A. Ohta, Hiroyuki Kobayashi, 1994 .

Palladium‐Catalyzed Arylation of Furan, Thiophene, Benzo(b)furan, and Benzo(b)thiophene.

Y. Aoyagi, A. Ohta, A. Miyafuji, 1991 .

First Total Synthesis of (.+‐.)‐Oxerine.

Y. Aoyagi, A. Ohta, Hiroyuki Kobayashi, 2010 .

Synthesis of Argvalin and Its Related Compound

A. Kojima, Y. Aoyagi, A. Ohta, 1988 .

Synthesis of arglecin

Y. Aoyagi, A. Ohta, H. Miyamae, 1987 .

Approach to the Synthesis of Astechrome

Y. Aoyagi, A. Ohta, Hao Jing, 1993 .

Synthesis of 2-(indol-3-yl) methyl-5-methylpyrazines, the skeleton of astechrome

Y. Aoyagi, Miki Goto, A. Maeda, 1992 .

First Synthesis of (+)-Septorine

Terumi Saito, A. Kojima, Kayoko Kobayashi, 1991 .

Emeheterone : synthesis and structural revision

A. Kojima, Y. Aoyagi, A. Ohta, 1990 .

Synthesis of rabdokunmin C analogues and their inhibitory effect on NF-κB activation.

Yong-ri Jin, Y. Adachi, N. Ohno, 2011, Bioorganic & medicinal chemistry.

Semisynthesis of C-ring modified triptolide analogues and their cytotoxic activities.

T. Matsuzaki, R. Aiyama, Y. Aoyagi, 2006, Bioorganic & medicinal chemistry letters.

Semisynthesis of triptolide analogues: effect of γ-lactone and C-14 substituents on cytotoxic activities.

T. Matsuzaki, R. Aiyama, Y. Aoyagi, 2011, Bioorganic & medicinal chemistry letters.

Garcinielliptone G from Garcinia subelliptica Induces Apoptosis in Acute Leukemia Cells

Satoshi Yotsumoto, H. Inoue, T. Kinoshita, 2021, Molecules.

Conformational behavior of oxygenated mycobacterial mycolic acids from Mycobacterium bovis BCG.

D. Minnikin, S. Hirono, H. Gouda, 2007, Biochimica et biophysica acta.

Location of functional groups in mycobacterial meromycolate chains; the recognition of new structural principles in mycolic acids.

Tsuyoshi Fujita, D. Minnikin, H. Naoki, 2002, Microbiology.

Effect of alkylpyrazine derivatives on the duration of pentobarbital-induced sleep, picrotoxicin-induced convulsion and gamma-aminobutyric acid (GABA) levels in the mouse brain.

Y. Aoyagi, A. Ohta, K. Yamada, 2001, Biological & pharmaceutical bulletin.

Abietane diterpenoids and a sesquiterpene pyridine alkaloid from Euonymus lutchuensis.

T. Kinoshita, Ayumi Watanabe, Y. Aoyagi, 2013, Journal of natural products.

Synthesis of 1-O-monoacyl or 12-O-monoacyl, 1-,12-O-diacyl-, and 11,12-dehydrated excisanin A 7,14-acetonides and their cytotoxic activity.

Yong-ri Jin, Yumi Nishioka, Y. Aoyagi, 2006, Bioorganic & medicinal chemistry.

Methyl dehydroabietate counters high fat diet-induced insulin resistance and hepatic steatosis by modulating peroxisome proliferator-activated receptor signaling in mice.

T. Nonogaki, Y. Aoyagi, K. Takeya, 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

1O, 20O-diacetyl kamebakaurin protects against acetaminophen-induced hepatotoxicity in mice.

N. Miura, Yong-ri Jin, Y. Adachi, 2018, Biomedical research.

First asymmetric synthesis of CJ-14877 and its enantiomer and their interleukin-1beta inhibitory activities.

Y. Adachi, N. Ohno, Y. Aoyagi, 2009, Bioorganic & medicinal chemistry letters.

Tricalysiolides A-F, new rearranged ent-kaurane diterpenes from Tricalysia dubia

Y. Takeda, T. Kinoshita, H. Otsuka, 2006 .

Excisanin H, a novel cytotoxic 14,20-epoxy-ent-kaurene diterpenoid, and three new ent-kaurene diterpenoids from Rabdosia excisa.

Y. Aoyagi, M. Gui, K. Takeya, 2004, Journal of Natural Products.

Synthesis of 1-O-acyl- and 1-oxo-kamebanin analogues and their cytotoxic activity.

Yong-ri Jin, Y. Fujii, Y. Aoyagi, 2023, Bioorganic & medicinal chemistry letters.

Antibacterial Novel Phenolic Diterpenes from Podocarpus macrophyllus

T. Koyama, T. Akiyama, Y. Aoyagi, 2022 .

New Diterpenoids from Tricalysia dubia

T. Kinoshita, Y. Aoyagi, K. Takeya, 2007 .

The isolation and structure elucidation of a new sesquiterpene lactone from the poisonous plant Coriaria japonica (Coriariaceae).

T. Kinoshita, Y. Aoyagi, K. Takeya, 2005, Chemical & pharmaceutical bulletin.