Shingo Arakawa

发表

Utilization of glutathione S-transferase Mu 1- and Theta 1-null mice as animal models for absorption, distribution, metabolism, excretion and toxicity studies

Shingo Arakawa, 2013, Expert opinion on drug metabolism & toxicology.

Resistance to acetaminophen-induced hepatotoxicity in glutathione S-transferase Mu 1-null mice.

Y. Yamazoe, K. Fujimoto, Shingo Arakawa, 2012, The Journal of toxicological sciences.

Decreased hepatic phosphorylated p38 mitogen-activated protein kinase contributes to attenuation of thioacetamide-induced hepatic necrosis in diet-induced obese mice.

M. Shirai, M. Teranishi, Shingo Arakawa, 2016, The Journal of toxicological sciences.

Characterization of Phenotypes in Gstm1-null Mice by Cytosolic and in Vivo Metabolic Studies Using 1,2-Dichloro-4-Nitrobenzene

S. Manabe, T. Yamoto, M. Uchiyama, 2006, Drug Metabolism and Disposition.

Characterization of phenotypes in Gstm1 -null mice by cytosolic and in vivo metabolic studies using DCNB

S. Manabe, M. Uchiyama, Yosuke Ando, 2006 .

metabolic studies using DCNB

S. Manabe, M. Uchiyama, Yosuke Ando, 2006 .

Expression of the theta class GST isozyme, YdfYdf, in low GST dogs

S. Manabe, T. Yamoto, W. Takasaki, 2006, Archives of Toxicology.

Role of connexin 32 in acetaminophen toxicity in a knockout mice model.

A. Sanbuissho, M. Teranishi, Shingo Arakawa, 2014, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

Toxicokintic and toxicodynamic analysis of clofibrate based on free drug concentrations in nagase analbuminemia rats (NAR).

N. Kiyosawa, S. Manabe, Kyoko Watanabe, 2008, The Journal of toxicological sciences.

Antiepileptic Drug–Activated Constitutive Androstane Receptor Inhibits Peroxisome Proliferator–Activated Receptor α and Peroxisome Proliferator–Activated Receptor γ Coactivator 1α–Dependent Gene Expression to Increase Blood Triglyceride Levels

T. Hosaka, K. Yoshinari, M. Miyata, 2020, Molecular Pharmacology.

Methemoglobinemia Induced by 1,2-Dichloro-4-nitrobenzene in Mice with a Disrupted Glutathione S-Transferase Mu 1 Gene

N. Kiyosawa, S. Manabe, W. Takasaki, 2010, Drug Metabolism and Disposition.

Nuclear receptor CAR-ERα signaling regulates the estrogen sulfotransferase gene in the liver

Muluneh M. Fashe, T. Sueyoshi, M. Negishi, 2020, Scientific Reports.

glutathione S-transferase Mu 1 gene

N. Kiyosawa, S. Manabe, W. Takasaki, 2010 .

Phosphorylation of Farnesoid X Receptor at Serine 154 Links Ligand Activation With Degradation.

F. Gonzalez, T. Sueyoshi, M. Negishi, 2016, Molecular endocrinology.

Sensitivity of Liver Injury in Heterozygous Sod2 Knockout Mice Treated with Troglitazone or Acetaminophen

S. Manabe, T. Yamoto, S. Oda, 2009, Toxicologic pathology.

DS-8201a, A Novel HER2-Targeting ADC with a Novel DNA Topoisomerase I Inhibitor, Demonstrates a Promising Antitumor Efficacy with Differentiation from T-DM1

T. Agatsuma, K. Hagihara, Takehiro Hirai, 2016, Clinical Cancer Research.

Generation and Functional Characterization of Mice with a Disrupted Glutathione S-Transferase, Theta 1 Gene

S. Manabe, T. Yamoto, S. Oda, 2007, Drug Metabolism and Disposition.

Sex and circadian modulatory effects on rat liver as assessed by transcriptome analyses.

S. Manabe, A. Sanbuissho, M. Nishihara, 2011, The Journal of toxicological sciences.

Evaluation of Hepatic Glutathione Transferase Mu 1 and Theta 1 Activities in Humans and Mice Using Genotype Information

A. Shinagawa, W. Takasaki, K. Fujimoto, 2012, Drug Metabolism and Disposition.

and Mice Using Genotype Information

A. Shinagawa, W. Takasaki, K. Fujimoto, 2011 .

Effect of the metabolic capacity in rat liver S9 on the positive results of in vitro micronucleus tests.

T. Yamoto, K. Mori, Shingo Arakawa, 2019, The Journal of toxicological sciences.

A novel model of continuous depletion of glutathione in mice treated with L-buthionine (S,R)-sulfoximine.

S. Manabe, Mayumi Watanabe, W. Takasaki, 2003, The Journal of toxicological sciences.

Comprehensive analysis of hepatic gene and protein expression profiles on phenobarbital- or clofibrate-induced hepatic hypertrophy in dogs.

A. Sanbuissho, T. Yamoto, H. Nakayama, 2009, The Journal of toxicological sciences.

Effects of Restricted Feeding on Daily Fluctuations of Hepatic Functions Including P450 Monooxygenase Activities in Rats*

Kyoko Watanabe, Kazumi Ito, Shingo Arakawa, 2006, Journal of Biological Chemistry.

Thioacetamide-induced Hepatocellular Necrosis Is Attenuated in Diet-induced Obese Mice

M. Shirai, M. Teranishi, H. Miida, 2013, Journal of toxicologic pathology.