Kuo Du

发表

Hedgehog-YAP Signaling Pathway Regulates Glutaminolysis to Control Activation of Hepatic Stellate Cells.

R. Premont, A. Diehl, Jeongeun Hyun, 2018, Gastroenterology.

Succinate‐GPR‐91 receptor signalling is responsible for nonalcoholic steatohepatitis‐associated fibrosis: Effects of DHA supplementation

A. Diehl, M. Abdelmalek, C. Niu, 2020, Liver international : official journal of the International Association for the Study of the Liver.

Inhibiting xCT/SLC7A11 induces ferroptosis of myofibroblastic hepatic stellate cells but exacerbates chronic liver injury

J. Chi, A. Diehl, Seh-hoon Oh, 2021, Liver international : official journal of the International Association for the Study of the Liver.

Inhibiting xCT/SLC7A11 induces ferroptosis of myofibroblastic hepatic stellate cells and protects against liver fibrosis

J. Chi, A. Diehl, Seh-hoon Oh, 2019, bioRxiv.

Critical role of FoxO3a in alcohol-induced autophagy and hepatotoxicity.

W. Ding, Min You, H. Ni, 2013, The American journal of pathology.

Increased Glutaminolysis Marks Active Scarring in Nonalcoholic Steatohepatitis Progression

Ricardo Henao, A. Suzuki, C. Moylan, 2019, Cellular and molecular gastroenterology and hepatology.

Hedgehog–YAP Signaling Pathway Regulates Glutaminolysis to Control Hepatic Stellate Cell Activation

R. Premont, A. Diehl, Jeongeun Hyun, 2018 .

Removal of acetaminophen protein adducts by autophagy protects against acetaminophen-induced liver injury in mice.

Mitchell R. McGill, H. Jaeschke, W. Ding, 2016, Journal of hepatology.

Induction of mitochondrial biogenesis protects against acetaminophen hepatotoxicity.

Mitchell R. McGill, T. Asselah, H. Jaeschke, 2017, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Resveratrol prevents protein nitration and release of endonucleases from mitochondria during acetaminophen hepatotoxicity.

Mitchell R. McGill, H. Jaeschke, Kuo Du, 2015, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Critical review of resveratrol in xenobiotic-induced hepatotoxicity.

Mitchell R. McGill, H. Jaeschke, Kuo Du, 2015, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential

H. Jaeschke, A. Ramachandran, Kuo Du, 2016, Redox biology.

Epithelial splicing regulatory protein 2-mediated alternative splicing reprograms hepatocytes in severe alcoholic hepatitis.

I. Rusyn, Zhaoli Sun, H. Tsukamoto, 2020, The Journal of clinical investigation.

Differential susceptibility to acetaminophen-induced liver injury in sub-strains of C57BL/6 mice: 6N versus 6J.

H. Jaeschke, M. Bourdi, B. Woolbright, 2016, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Mitochondrial Protein Adduct and Superoxide Generation are Prerequisites for Early Activation of c-Jun N-terminal Kinase within the Cytosol after an Acetaminophen Overdose in Mice.

H. Jaeschke, A. Ramachandran, Nga T. Nguyen, 2020, Toxicology letters.

Mitochondrial protein adducts formation and mitochondrial dysfunction during N-acetyl-m-aminophenol (AMAP)-induced hepatotoxicity in primary human hepatocytes.

Mitchell R. McGill, H. Jaeschke, K. Dorko, 2015, Toxicology and applied pharmacology.

Mito-tempo protects against acute liver injury but induces limited secondary apoptosis during the late phase of acetaminophen hepatotoxicity

H. Jaeschke, A. Ramachandran, W. Ding, 2018, Archives of Toxicology.

Mitochondria-targeted antioxidant Mito-Tempo protects against acetaminophen hepatotoxicity

H. Jaeschke, A. Farhood, Kuo Du, 2016, Archives of Toxicology.

Lower susceptibility of female mice to acetaminophen hepatotoxicity: Role of mitochondrial glutathione, oxidant stress and c-jun N-terminal kinase.

Mitchell R. McGill, H. Jaeschke, C. Williams, 2014, Toxicology and applied pharmacology.

MITOCHONDRIAL OXIDATIVE STRESS AND BIOGENESIS DURING ACETAMINOPHEN HEPATOTOXICITY

Kuo Du, 2017 .

Single cell RNA sequencing identifies YAP1-dependent hepatic mesothelial progenitors in fibrolamellar carcinoma.

S. Gregory, D. Hsu, R. Premont, 2019, The American journal of pathology.

Dual Role of Epidermal Growth Factor Receptor in Liver Injury and Regeneration after Acetaminophen Overdose in Mice

Mitchell R. McGill, H. Jaeschke, B. Bhushan, 2017, Toxicological sciences : an official journal of the Society of Toxicology.

Hepatocyte Smoothened Activity Controls Susceptibility to Insulin Resistance and Nonalcoholic Fatty Liver Disease

Ricardo Henao, S. Gregory, J. M. Brown, 2022, Cellular and molecular gastroenterology and hepatology.

Pathophysiological significance of c-jun N-terminal kinase in acetaminophen hepatotoxicity

Mitchell R. McGill, H. Jaeschke, Kuo Du, 2015, Expert opinion on drug metabolism & toxicology.

Editor's Highlight: Metformin Protects Against Acetaminophen Hepatotoxicity by Attenuation of Mitochondrial Oxidant Stress and Dysfunction.

H. Jaeschke, A. Ramachandran, P. Krishnamurthy, 2016, Toxicological sciences : an official journal of the Society of Toxicology.

The gap junction inhibitor 2-aminoethoxy-diphenyl-borate protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes and c-jun N-terminal kinase activation.

Mitchell R. McGill, M. Vinken, H. Jaeschke, 2013, Toxicology and applied pharmacology.

The role of the c-Jun N-terminal kinases 1/2 and receptor-interacting protein kinase 3 in furosemide-induced liver injury

Mitchell R. McGill, H. Jaeschke, W. Ding, 2015, Xenobiotica; the fate of foreign compounds in biological systems.

Liuweiwuling tablets protect against acetaminophen hepatotoxicity: What is the protective mechanism?

H. Jaeschke, Kuo Du, 2016, World journal of gastroenterology.

Benzyl alcohol protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes but causes mitochondrial dysfunction and cell death at higher doses.

Mitchell R. McGill, H. Jaeschke, Kuo Du, 2015, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Benzyl Alcohol: A novel treatment for acetaminophen overdose?

H. Jaeschke, Kuo Du, 2015, Hepatology.

Pathophysiological significance of c-jun N-terminal kinase in acetaminophen hepatotoxicity

Mitchell R. McGill, H. Jaeschke, Kuo Du, 2015, Expert opinion on drug metabolism & toxicology.

Critical role of FoxO3a in alcohol-induced autophagy and hepatotoxicity.

W. Ding, Min You, Kuo Du, 2013, The American journal of pathology.

Mito-tempo protects against acute liver injury but induces limited secondary apoptosis during the late phase of acetaminophen hepatotoxicity

H. Jaeschke, A. Ramachandran, W. Ding, 2018, Archives of Toxicology.

Induction of mitochondrial biogenesis protects against acetaminophen hepatotoxicity.

Mitchell R. McGill, T. Asselah, H. Jaeschke, 2017, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

The gap junction inhibitor 2-aminoethoxy-diphenyl-borate protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes and c-jun N-terminal kinase activation.

M. Vinken, H. Jaeschke, A. Farhood, 2013, Toxicology and applied pharmacology.

Differential susceptibility to acetaminophen-induced liver injury in sub-strains of C57BL/6 mice: 6N versus 6J.

H. Jaeschke, M. Bourdi, B. Woolbright, 2016, Food and Chemical Toxicology.

Critical review of resveratrol in xenobiotic-induced hepatotoxicity.

Mitchell R. McGill, H. Jaeschke, Kuo Du, 2015, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.