Jonathan Iaconelli

发表

HDAC6 Modulates Signaling Pathways Relevant to Synaptic Biology and Neuronal Differentiation in Human Stem Cell-Derived Neurons

Rakesh Karmacharya, Jonathan Iaconelli, Lucius Xuan, 2019, International journal of molecular sciences.

Small‐Molecule Stimulators of NRF1 Transcriptional Activity

P. Schultz, M. Hull, Michael J. Bollong, 2020, Chembiochem : a European journal of chemical biology.

Lysine Deacetylation by HDAC6 Regulates the Kinase Activity of AKT in Human Neural Progenitor Cells.

S. Haggarty, Ralph Mazitschek, Rakesh Karmacharya, 2017, ACS chemical biology.

Perturbational Profiling of Metabolites in Patient Fibroblasts Implicates α-Aminoadipate as a Potential Biomarker for Bipolar Disorder

B. Cohen, D. Öngür, C. Clish, 2016, Molecular Neuropsychiatry.

2-Sulfonyl pyridines as tunable, cysteine-reactive electrophiles.

P. Schultz, B. Cravatt, C. Zambaldo, 2020, Journal of the American Chemical Society.

Discovery and SAR studies of 3-amino-4-(phenylsulfonyl)tetrahydrothiophene 1,1-dioxides as non-electrophilic antioxidant response element (ARE) activators.

M. Kumar, P. Schultz, A. Chatterjee, 2021, Bioorganic chemistry.

Farnesyl transferase inhibitors impair chromosomal maintenance in cell lines and human tumors by compromising CENP-E and CENP-F function

J. Snyder, A. Marcus, F. Khuri, 2007, Molecular Cancer Therapeutics.

Disease signatures for schizophrenia and bipolar disorder using patient-derived induced pluripotent stem cells

Rakesh Karmacharya, Joanne H. Huang, Jonathan Iaconelli, 2016, Molecular and Cellular Neuroscience.

HDAC6 Inhibitors Modulate Lys49 Acetylation and Membrane Localization of β-Catenin in Human iPSC-Derived Neuronal Cells

S. Haggarty, S. Schreiber, Ralph Mazitschek, 2014, ACS chemical biology.

YAP-dependent proliferation by a small molecule targeting annexin A2

P. Schultz, F. Camargo, Pengyu Yang, 2021, Nature Chemical Biology.

Unbiased Metabolite Profiling of Schizophrenia Fibroblasts under Stressful Perturbations Reveals Dysregulation of Plasmalogens and Phosphatidylcholines.

B. Cohen, D. Öngür, C. Clish, 2017, Journal of proteome research.

Optimization of 3-aminotetrahydrothiophene 1,1-dioxides with improved potency and efficacy as non-electrophilic antioxidant response element (ARE) activators.

A. Chatterjee, Yunjin Jung, L. Lairson, 2023, Bioorganic & medicinal chemistry letters.

Niche-Based Screening in Multiple Myeloma Identifies a Kinesin-5 Inhibitor with Improved Selectivity over Hematopoietic Progenitors.

T. Golub, P. Clemons, S. Schreiber, 2015, Cell reports.

S-lactoyl modification of KEAP1 by a reactive glycolytic metabolite activates NRF2 signaling

M. Kumar, P. Schultz, R. L. Wiseman, 2023, Proceedings of the National Academy of Sciences of the United States of America.

TERT activation targets DNA methylation and multiple aging hallmarks

Michael J. Bollong, Jonathan Iaconelli, Jiexi Li, 2024, Cell.

HDAC 6 Inhibitors Modulate Lys 49 Acetylation and Membrane Localization of β-Catenin in Human iPSC-Derived Neuronal Cells

S. Haggarty, Rakesh Karmacharya, Joanne H. Huang, 2015 .