A. Sargeant

发表

Efficacy of novel histone deacetylase inhibitor, AR42, in a mouse model of, human T-lymphotropic virus type 1 adult T cell lymphoma.

C. Chen, S. Fernandez, M. Lairmore, 2011, Leukemia research.

Escalated as compared with standard doses of doxorubicin in BACOP therapy for patients with non-Hodgkin's lymphoma.

M. Gospodarowicz, V. Bramwell, L. Shepherd, 1993, The New England journal of medicine.

Antitumor effects of BI-D1870 on human oral squamous cell carcinoma

C. Chiu, L. Bai, J. Weng, 2014, Cancer Chemotherapy and Pharmacology.

A novel indole-3-carbinol derivative inhibits the growth of human oral squamous cell carcinoma in vitro.

M. Tsai, C. Chiu, L. Bai, 2010, Oral oncology.

Palliative Gastrectomy Prolongs Survival of Metastatic Gastric Cancer Patients with Normal Preoperative CEA or CA19-9 Values: A Retrospective Cohort Study

Horng-ren Yang, L. Jeng, Mei-Due Yang, 2016, Gastroenterology research and practice.

A Review of the Existing Grading Schemes and a Proposal for a Modified Grading Scheme for Prostatic Lesions in TRAMP Mice

S. Kulp, C. Chen, T. Rosol, 2012, Toxicologic pathology.

Scientific and Regulatory Policy Committee Points to Consider: Histopathologic Evaluation in Safety Assessment Studies for PEGylated Pharmaceutical Products

R. Garman, B. Bolon, A. Braendli-Baiocco, 2018, Toxicologic pathology.

Intranuclear paracrystals observed in striated muscle specific LIM protein‐deficient mouse cardiomyocytes

G. Faulkner, Y. Nishijima, M. Yamaguchi, 2007, Microscopy research and technique.

OSU-A9 inhibits pancreatic cancer cell lines by modulating p38-JAK-STAT3 signaling

Y. Hsu, L. Bai, J. Weng, 2017, Oncotarget.

A meta-analysis of two randomised trials of early chemotherapy in asymptomatic metastatic colorectal cancer

R. Goldberg, D. Tu, M. Moore, 2005, British Journal of Cancer.

T315 Decreases Acute Myeloid Leukemia Cell Viability through a Combination of Apoptosis Induction and Autophagic Cell Death

C. Chiu, L. Bai, J. Weng, 2016, International journal of molecular sciences.

Background Pathological Changes in Minipigs

K. Helke, Binod Jacob, S. McKeag, 2016, Toxicologic pathology.

Nervous System Sampling for General Toxicity and Neurotoxicity Studies in the Laboratory Minipig With Emphasis on the Göttingen Minipig

R. Garman, B. Bolon, I. Pardo, 2021, Toxicologic pathology.

Targeting of the Akt-Nuclear Factor-κB Signaling Network by [1-(4-Chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol (OSU-A9), a Novel Indole-3-Carbinol Derivative, in a Mouse Model of Hepatocellular Carcinoma

S. Kulp, Dasheng Wang, T. Patel, 2009, Molecular Pharmacology.

G15, a GPR30 antagonist, induces apoptosis and autophagy in human oral squamous carcinoma cells.

Dasheng Wang, C. Chiu, L. Bai, 2013, Chemico-biological interactions.

Histone Deacetylase Inhibitors Stimulate Histone H3 Lysine 4 Methylation in Part Via Transcriptional Repression of Histone H3 Lysine 4 Demethylases

J. Byrd, S. Kulp, C. Teng, 2011, Molecular Pharmacology.

Targeting endoplasmic reticulum stress and Akt with OSU-03012 and gefitinib or erlotinib to overcome resistance to epidermal growth factor receptor inhibitors.

S. Kulp, Dasheng Wang, M. Yamaguchi, 2008, Cancer research.

Pigs in Toxicology

K. Helke, Binod Jacob, S. McKeag, 2016, Toxicologic pathology.

Multimodel assessment of BRCA1 mutations in Taiwanese (ethnic Chinese) women with early-onset, bilateral or familial breast cancer

King-Jen Chang, Y. Chien, W. Hwu, 2012, Journal of Human Genetics.

OSU-HDAC42, a histone deacetylase inhibitor, blocks prostate tumor progression in the transgenic adenocarcinoma of the mouse prostate model.

S. Kulp, Yu-Chieh Wang, S. Clinton, 2008, Cancer research.

Preclinical Efficacy and Safety Evaluation of Novel Small-Molecule Targeted Agents for the Prevention and Treatment of Prostate Cancer

A. Sargeant, 2009 .

A potent indole-3-carbinol derived antitumor agent with pleiotropic effects on multiple signaling pathways in prostate cancer cells.

S. Kulp, Dasheng Wang, M. Tsai, 2007, Cancer research.

BX795, a TBK1 inhibitor, exhibits antitumor activity in human oral squamous cell carcinoma through apoptosis induction and mitotic phase arrest.

Tzong-Ming Shieh, C. Chiu, L. Bai, 2015, European journal of pharmacology.

Commentary: the role of the toxicologic pathologist in academia.

C. Scudamore, L. Wancket, W. Haschek, 2015, Veterinary pathology.

Chemopreventive and Bioenergetic Signaling Effects of PDK1/Akt Pathway Inhibition in a Transgenic Mouse Model of Prostate Cancer

S. Kulp, M. Yamaguchi, S. Clinton, 2007, Toxicologic pathology.

OSU-A9, a potent indole-3-carbinol derivative, suppresses breast tumor growth by targeting the Akt-NF-kappaB pathway and stress response signaling.

C. Shapiro, S. Kulp, Dasheng Wang, 2009, Carcinogenesis.

Cardiac Rhabdomyoma in Four Göttingen Minipigs

Jennifer L. Lamoureux, E. Ehrhart, A. Sargeant, 2023, Toxicologic pathology.

Myocardial fibrosis, inflammation, and altered cardiac gene expression profiles in rats exposed to a predator-based model of posttraumatic stress disorder

S. Seeley, P. Zoladz, B. Rorabaugh, 2020, Stress.

Animal Models in Toxicologic Research: Pig

K. Helke, A. Sargeant, Keith Nelson, 2022, Haschek and Rousseaux's Handbook of Toxicologic Pathology.

Antitumor activity of a novel histone deacetylase inhibitor (S)-HDAC42 in oral squamous cell carcinoma.

Tzong-Ming Shieh, S. Pan, C. Chiu, 2011, Oral oncology.

OSU-A9, an indole-3-carbinol derivative, induces cytotoxicity in acute myeloid leukemia through reactive oxygen species-mediated apoptosis.

C. Chiu, S. Yeh, L. Bai, 2013, Biochemical pharmacology.

OSU-03012 sensitizes TIB-196 myeloma cells to imatinib mesylate via AMP-activated protein kinase and STAT3 pathways.

Cheng-Wen Lin, C. Chiu, L. Bai, 2010, Leukemia research.

The role of adjuvant chemotherapy for patients with stage II and stage III gastric adenocarcinoma after surgery plus D2 lymph node dissection: a real-world observation

Horng-ren Yang, L. Jeng, C. Chiu, 2016, SpringerPlus.

Targeting endoplasmic reticulum stress and Akt with OSU-03012 and gefitinib or erlotinib to overcome resistance to epidermal growth factor receptor inhibitors.

S. Kulp, Dasheng Wang, M. Yamaguchi, 2008, Cancer research.

Hepatitis C infection is associated with hepatic toxicity but does not compromise the survival of patients with diffuse large B cell lymphoma treated with rituximab-based chemotherapy.

C. Chiu, S. Yeh, L. Bai, 2015, Leukemia research.

Using Deep Learning Artificial Intelligence Algorithms to Verify N-Nitroso-N-Methylurea and Urethane Positive Control Proliferative Changes in Tg-RasH2 Mouse Carcinogenicity Studies

Colin A. Doolan, D. Rudmann, A. Sargeant, 2020, Toxicologic pathology.