Jonathan J. Cherry

发表

An SMA project report: neural cell-based assays derived from human embryonic stem cells.

S. Stice, Soojung Shin, Patricia G. Wilson, 2007, Stem cells and development.

Binding of Human Papillomavirus Type 16 E6 to E6AP Is Not Required for Activation of hTERT

E. Androphy, P. Sekaric, Jonathan J. Cherry, 2007, Journal of Virology.

Differential regulation of the SMN2 gene by individual HDAC proteins.

E. Androphy, M. Evans, Jonathan J. Cherry, 2011, Biochemical and biophysical research communications.

ML372 blocks SMN ubiquitination and improves spinal muscular atrophy pathology in mice.

M. Ferrer, K. Fischbeck, E. Androphy, 2016, JCI insight.

Determinants of stability for the E6 protein of papillomavirus type 16.

E. Androphy, J. Baleja, Yuqi Liu, 2009, Journal of molecular biology.

Optimization of a series of heterocycles as survival motor neuron gene transcription enhancers.

C. Lorson, M. Glicksman, G. Cuny, 2017, Bioorganic & medicinal chemistry letters.

Structure Based Identification and Characterization of Flavonoids That Disrupt Human Papillomavirus-16 E6 Function

E. Androphy, J. Baleja, Yuqi Liu, 2013, PloS one.

Therapeutic strategies for the treatment of spinal muscular atrophy.

E. Androphy, Jonathan J. Cherry, J. Cherry, 2012, Future medicinal chemistry.

Discovery, synthesis, and biological evaluation of novel SMN protein modulators.

E. Androphy, Noel Southall, C. Austin, 2011, Journal of medicinal chemistry.

Targeting 3′ and 5′ untranslated regions with antisense oligonucleotides to stabilize frataxin mRNA and increase protein expression

Jun Wang, M. Napierala, D. Lynch, 2021, Nucleic acids research.

Assays for the identification and prioritization of drug candidates for spinal muscular atrophy.

Maureen M Lynes, L. Rubin, F. Tiziano, 2014, Assay and drug development technologies.

Discovery of a Small Molecule Probe That Post-Translationally Stabilizes the Survival Motor Neuron Protein for the Treatment of Spinal Muscular Atrophy.

C. Lorson, E. Androphy, M. Glicksman, 2017, Journal of medicinal chemistry.

Enhancement of SMN protein levels in a mouse model of spinal muscular atrophy using novel drug-like compounds

C. Lorson, E. Androphy, M. Glicksman, 2013, EMBO molecular medicine.

Identification of Novel Compounds That Increase SMN Protein Levels Using an Improved SMN2 Reporter Cell Assay

E. Androphy, M. Glicksman, G. Cuny, 2012, Journal of biomolecular screening.

Identification of inhibitors to papillomavirus type 16 E6 protein based on three-dimensional structures of interacting proteins.

E. Androphy, J. Baleja, Zhiguo Liu, 2006, Antiviral research.

In vitro and in vivo effects of 2,4 diaminoquinazoline inhibitors of the decapping scavenger enzyme DcpS: Context-specific modulation of SMN transcript levels

Timothy L. Foley, E. Androphy, Baohong Zhang, 2017, PloS one.

Design of Potent mRNA Decapping Scavenger Enzyme (DcpS) Inhibitors with Improved Physicochemical Properties To Investigate the Mechanism of Therapeutic Benefit in Spinal Muscular Atrophy (SMA).

Timothy L. Foley, P. Loria, A. Narayanan, 2017, Journal of medicinal chemistry.