R. Oerlemans

发表

Inhibition of tumour necrosis factor alpha production by activated T cells of rheumatoid arthritis patients by novel anti-folate drugs: an ex vivo pilot study

G. Jansen, B. Dijkmans, J. van der Heijden, 2005, Arthritis Research & Therapy.

The multidrug resistance protein breast cancer resistance protein (BCRP) protects adipose-derived stem cells against ischemic damage

H. Niessen, G. Schuurhuis, A. Rossum, 2012, Cell Biology and Toxicology.

Expression profiling of ABC transporters in peripheral blood lymphocytes and monocyte-derived macrophages of rheumatoid arthritis patients

G. Peters, B. Dijkmans, W. Lems, 2020 .

The proteasome inhibitor bortezomib inhibits the release of NFkappaB-inducible cytokines and induces apoptosis of activated T cells from rheumatoid arthritis patients.

B. Dijkmans, W. Lems, G. Jansen, 2009, Clinical and experimental rheumatology.

The proteasome inhibitor bortezomib inhibits the release of NF kappa B-inducible cytokines and induces apoptosis of activated T cells from rheumatoid arthritis patients

B. Dijkmans, W. Lems, G. Jansen, 2009 .

Molecular basis of bortezomib resistance: proteasome subunit beta5 (PSMB5) gene mutation and overexpression of PSMB5 protein.

G. Peters, B. Dijkmans, B. Ylstra, 2008, Blood.

T lymphocytes impair P-glycoprotein function during neuroinflammation.

H. D. de Vries, G. Scheffer, R. Scheper, 2010, Journal of autoimmunity.

Inactivating PSMB 5 mutations and P-glycoprotein ( MDR 1 / ABCB 1 ) mediate resistance to proteasome inhibitors : ex vivo efficacy of ( immuno ) proteasome inhibitors in mononuclear blood cells from rheumatoid arthritis patients

G. Peters, B. Dijkmans, Y. Assaraf, 2013 .

Inactivating PSMB 5 Mutations and P-Glycoprotein ( Multidrug Resistance-Associated Protein / ATP-Binding Cassette B 1 ) Mediate Resistance to Proteasome Inhibitors : Ex Vivo Efficacy of ( Immuno ) Proteasome Inhibitors in Mononuclear Blood Cells from Patients with Rheumatoid Arthritis

G. Peters, B. Dijkmans, Y. Assaraf, 2012 .

Sulfasalazine Down-Regulates the Expression of the Angiogenic Factors Platelet-Derived Endothelial Cell Growth Factor/Thymidine Phosphorylase and Interleukin-8 in Human Monocytic-Macrophage THP1 and U937 Cells

G. Peters, B. Dijkmans, Y. Assaraf, 2004, Molecular Pharmacology.

Molecular basis of bortezomib/Velcade ® resistance: Proteasome subunit β 5 (PSMB5) gene mutation and overexpression of PSMB5 protein

Katharina, Gerrit, B. Dijkmans, 2008 .

Molecular mechanisms of resistance to classical and experimental anti-rheumatic drugs

R. Scheper, T. D. Gruijl, J. W. Heijden, 2010 .

Involvement of breast cancer resistance protein expression on rheumatoid arthritis synovial tissue macrophages in resistance to methotrexate and leflunomide.

B. Dijkmans, W. Lems, Y. Assaraf, 2009, Arthritis and rheumatism.

Effect of age on functional P‐glycoprotein in the blood‐brain barrier measured by use of (R)‐[11C]verapamil and positron emission tomography

Mark Lubberink, Gert Luurtsema, M. Lubberink, 2006, Clinical pharmacology and therapeutics.

ABC drug transporters and immunity: novel therapeutic targets in autoimmunity and cancer

G. Jansen, G. Scheffer, R. Scheper, 2009, Journal of leukocyte biology.

Acquired resistance of human T cells to sulfasalazine: stability of the resistant phenotype and sensitivity to non-related DMARDs

Y. Assaraf, G. Jansen, G. Scheffer, 2004, Annals of the rheumatic diseases.

Sulfasalazine is a potent inhibitor of the reduced folate carrier: implications for combination therapies with methotrexate in rheumatoid arthritis.

B. Dijkmans, W. Lems, Y. Assaraf, 2004, Arthritis and rheumatism.

The multidrug resistance protein breast cancer resistance protein (BCRP) protects adipose-derived stem cells against ischemic damage

H. Niessen, G. Schuurhuis, A. Rossum, 2012, Cell Biology and Toxicology.

Acquired resistance to chloroquine in human CEM T cells is mediated by multidrug resistance-associated protein 1 and provokes high levels of cross-resistance to glucocorticoids.

B. Dijkmans, W. Lems, Y. Assaraf, 2006, Arthritis and rheumatism.

Development of sulfasalazine resistance in human T cells induces expression of the multidrug resistance transporter ABCG2 (BCRP) and augmented production of TNFα

B. Dijkmans, W. Lems, C. Schalkwijk, 2004, Annals of the rheumatic diseases.

Inactivating PSMB5 Mutations and P-Glycoprotein (Multidrug Resistance-Associated Protein/ATP-Binding Cassette B1) Mediate Resistance to Proteasome Inhibitors: Ex Vivo Efficacy of (Immuno)Proteasome Inhibitors in Mononuclear Blood Cells from Patients with Rheumatoid Arthritis

G. Peters, B. Dijkmans, Y. Assaraf, 2012, Journal of Pharmacology and Experimental Therapeutics.

Molecular Mechanisms of Bortezomib Resistance in Acute Lymphoblastic Leukemia Cells in Comparison with Multiple Myeloma Cells.

G. Jansen, J. Cloos, G. Kaspers, 2007 .

Methotrexate analogues display enhanced inhibition of TNF-α production in whole blood from RA patients

B. Dijkmans, A. Gerards, Y. Assaraf, 2014, Scandinavian journal of rheumatology.

Proteasome inhibition and mechanism of resistance to a synthetic, library-based hexapeptide

G. Peters, B. Dijkmans, R. Shoemaker, 2018, Investigational New Drugs.

Folate receptor beta as a potential delivery route for novel folate antagonists to macrophages in the synovial tissue of rheumatoid arthritis patients.

B. Dijkmans, W. Lems, P. Tak, 2009, Arthritis and rheumatism.

Folate Receptor as a Potential Delivery Route for Novel Folate Antagonists to Macrophages in the Synovial Tissue of Rheumatoid Arthritis Patients

B. Dijkmans, W. Lems, P. Tak, 2008 .

dendritic cell migration A role for multidrug resistance protein 4 (MRP4; ABCC4) in human

D. Curiel, J. Gillet, G. Scheffer, 2013 .

A role for multidrug resistance protein 4 (MRP4; ABCC4) in human dendritic cell migration.

D. Curiel, T. D. de Gruijl, G. Jansen, 2008, Blood.

Sulfasalazine sensitises human monocytic/macrophage cells for glucocorticoids by upregulation of glucocorticoid receptor α and glucocorticoid induced apoptosis

B. Dijkmans, W. Lems, Y. Assaraf, 2007, Annals of the rheumatic diseases.

Dendritic Cell Migration a Role for Multidrug Resistance Protein 4 (mrp4; Abcc4) in Human

D. Curiel, J. Gillet, G. Scheffer, 2008 .

The contribution of ABC transporters to dendritic cell development and function

G. Scheffer, R. Scheper, A. Reurs, 2011 .

Molecular basis of bortezomib resistance: proteasome subunit β5 (PSMB5) gene mutation and overexpression of PSMB5 protein

R. Arceci, B. Ylstra, Y. Assaraf, 2009 .