P. Chello

发表

Alterations in the kinetics of methotrexate transport during growth of L1210 murine leukemia cells in culture.

F. Sirotnak, P. Chello, D. M. Dorick, 1980, Molecular pharmacology.

5-methyl-5,6,7,8-tetrahydropteroyl oligo-gamma-L-glutamates: synthesis and kinetic studies with methionine synthetase from bovine brain.

L. Deangelis, J. Bertino, J. Coward, 1975, Biochemistry.

Stereospecificity at carbon 6 of fomyltetrahydrofolate as a competitive inhibitor of transport and cytotoxicity of methotrexate in vitro.

J. Montgomery, F. Sirotnak, D. M. Moccio, 1979, Biochemical pharmacology.

Growth inhibitory, transport and biochemical properties of the gamma-glutamyl and gamma-aspartyl peptides of methotrexate in L1210 leukemia cells in vitro.

J. Montgomery, F. Sirotnak, P. Chello, 1978, Biochemical pharmacology.

Biochemical and pharmacologic properties of a new folate analog, 10-deaza-aminopterin, in mice.

F. Sirotnak, D. M. Moccio, P. Chello, 1982, Cancer treatment reports.

Further studies stereospecificity at carbon 6 for membrane transport of tetrahydrofolates. Diastereoisomers of 5-methyltetrahydrofolates as competitive inhibitors of transport of methotrexate in L1210 cells.

F. Sirotnak, P. Chello, R. Kisliuk, 1982, Biochemical pharmacology.

Elevation of dihydrofolate reductase, thymidylate synthetase, and thymidine kinase in cultured mammalian cells after exposure to folate antagonists.

L. Deangelis, J. Bertino, C. Mcqueen, 1976, Cancer research.

Comparative properties of trypanosomal and mammalian thymidine kinases.

P. Chello, J. Jaffe, Paul L. Chello, 1972, Comparative biochemistry and physiology. B, Comparative biochemistry.

Specificity of systems mediating transport of adenosine, 9-beta-d-arabinofuranosyl-2-fluoroadenine, and other purine nucleoside analogues in L1210 cells.

J. Montgomery, F. Sirotnak, P. Chello, 1983, Cancer research.

Dependence of 5-methyltetrahydrofolate utilization by L5178Y murine leukemia cells in vitro on the presence of hydroxycobalamin and transcobalamin II.

J. Bertino, P. Chello, 1973, Cancer research.

Folate analog transport by plasma membrane vesicles isolated from L1210 leukemia cells.

F. Sirotnak, C. Yang, P. Chello, 1979, The Journal of biological chemistry.

Analog specific aberrancies in antifolate inhibition of L1210 cell dihydrofolate reductase.

J. Montgomery, F. Sirotnak, D. M. Moccio, 1980, Biochemical pharmacology.

Initial rate kinetics and evidence for duality of mediated transport of adenosine, related purine nucleosides, and nucleoside analogues in L1210 cells.

J. Montgomery, F. Sirotnak, C. Yang, 1983, Cancer research.

Synthesis and properties of the sulfonyl analogues of 4(5)-aminoimidazole-5(4)-carboxamide, 4(5)-(formylamino)imidazole-5(4)-carboxamide, guanine, and xanthine.

L. Yip, P. Chello, J. Parham, 1980, Journal of medicinal chemistry.

SYNTHESIS AND PROPERTIES OF THE SULFONYL ANALOGS OF 4(5)-AMINOIMIDAZOLE-5(4)-CARBOXAMIDE, 4(5)-(FORMYLAMINO)IMIDAZOLE-5(4)-CARBOXAMIDE, GUANINE, AND XANTHINE

L. Yip, P. Chello, J. Parham, 1980 .

Differential synthesis of methotrexate polyglutamates in normal proliferative and neoplastic mouse tissues in vivo.

F. Sirotnak, P. Chello, R. Poser, 1981, Cancer research.

Syntheses of alpha- and gamma-substituted amides, peptides, and esters of methotrexate and their evaluation as inhibitors of folate metabolism.

J. Montgomery, F. Sirotnak, P. Chello, 1982, Journal of medicinal chemistry.

Antitumor activity of a folate-cleaving enzyme, carboxypeptidase G 1 .

J. Bertino, B. Chabner, P. Chello, 1972, Cancer research.

Extracellular recovery of methotrexate-polyglutamates following efflux from L1210 leukemia cells.

F. Sirotnak, P. Chello, R. Poser, 1980, Biochemical pharmacology.

Isolation, partial purification, and properties of thymidine kinase from Trypanosoma (trypanozoon) brucei rhodesiense.

P. Chello, J. Jaffe, P. L. Chello, 1972, The Journal of parasitology.

Schedule-dependent synergism of methotrexate and vincristine against murine L1210 leukemia.

F. Sirotnak, D. M. Moccio, P. Chello, 1979, Cancer treatment reports.

Different effects of vincristine on methotrexate uptake by L1210 cells and mouse intestinal epithelia in vitro and in vivo.

F. Sirotnak, P. Chello, D. M. Dorick, 1979, Cancer research.

Sequential combination of methotrexate and vindesine in previously treated children with acute leukemia. A phase I-II study.

F. Sirotnak, D. Miller, C. Tan, 1984, American Journal of Clinical Oncology.

Increased schedule-dependent synergism of vindesine versus vincristine in combination with methotrexate against L1210 leukemia.

F. Sirotnak, P. Chello, 1981, Cancer treatment reports.

Synthesis of an N-aminopyrazinonium analogue of cytidine.

T. Chou, P. Chello, T. C. Lee, 1983, Journal of medicinal chemistry.

Therapeutic relevance of differences in the structural specificity of the transport systems for folate analogs in L1210 tumor cells and in isolated murine intestinal epithelial cells.

F. Sirotnak, P. Chello, D. M. Dorick, 1977, Cancer research.

Schedule-dependent synergism of methotrexate and vincristine against l1210 leukemia. Abstr.

F. Sirotnak, P. Chello, D. M. Dorick, 1978 .

Synthesis and Properties of 10-Benzylaminopterin

F. Sirotnak, P. Chello, M. A. Templeton, 1979 .

Specificity of the antifolate transport mechanism of mouse intestinal epithelia versus l1210 leukemia for n10 substituents. Abstr.

D. Hutchison, F. Sirotnak, P. Chello, 1976 .

SYNTHESES OF α‐ AND Γ‐SUBSTITUTED AMIDES, PEPTIDES, AND ESTERS OF METHOTREXATE AND THEIR EVALUATION AS INHIBITORS OF FOLATE METABOLISM

J. Montgomery, F. Sirotnak, P. Chello, 1982 .

Comparative effects of folate antagonists versus enzymatic folate depletion on folate and thymidine enzymes in cultured mammalian cells.

L. Deangelis, J. Bertino, C. Mcqueen, 1977, Cancer treatment reports.

Effect of methionine deprivation on L5178Y murine leukemia cells in culture interference with the antineoplastic effect of methotrexate.

J. Bertino, P. Chello, P. L. Chello, 1976, Biochemical pharmacology.