James C. Sacchettini

发表

TEXTAL TM : Artificial Intelligence Techniques for Automated Protein Structure Determination.

Thomas R. Ioerger, Kreshna Gopal, Reetal Pai, 2003 .

TEXTALTM: Artificial Intelligence Techniques for Automated Protein Structure Determination

Thomas R. Ioerger, Kreshna Gopal, Reetal Pai, 2003, IAAI.

Determining Relevant Features to Recognize Electron Density Patterns in X-ray Protein Crystallography

Thomas R. Ioerger, Kreshna Gopal, Tod D. Romo, 2005, J. Bioinform. Comput. Biol..

Weighting features to recognize 3D patterns of electron density in X-ray protein crystallography

Thomas R. Ioerger, Kreshna Gopal, Tod D. Romo, 2004, Proceedings. 2004 IEEE Computational Systems Bioinformatics Conference, 2004. CSB 2004..

Analysis of Protein-Ligand Interactions Using Localized Stereochemical Features

Thomas R. Ioerger, Reetal Pai, James C. Sacchettini, 2008, BIOCOMP.

TEXTAL: Crystallographic Protein Model Building Using AI and Pattern Recognition

Jacob N. Smith, Thomas R. Ioerger, Kreshna Gopal, 2006, AI Mag..

Specificity Normalization for Identifying Selective Inhibitors in Virtual Screening

Thomas R. Ioerger, Reetal Pai, James C. Sacchettini, 2008, BIOCOMP.

Extracting fractal features for analyzing protein structure

Thomas R. Ioerger, Yu Tao, James C. Sacchettini, 2002, Object recognition supported by user interaction for service robots.

Identification of Compounds with Potential Antibacterial Activity against Mycobacterium through Structure-Based Drug Screening

Hiroshi Sakamoto, Mitsuru Kitamura, Koji Morita, 2013, J. Chem. Inf. Model..

TEXTAL: AI-Based Structural Determination for X-ray Protein Crystallography

Jacob N. Smith, Thomas R. Ioerger, Kreshna Gopal, 2005, IEEE Intell. Syst..

Weighting features to recognize 3D patterns of electron density in X-ray protein crystallography

Thomas R. Ioerger, Kreshna Gopal, Tod D. Romo, 2004 .

TEXTAL: A Pattern Recognition System for Interpreting Electron Density Maps

Thomas R. Ioerger, James C. Sacchettini, Thomas Holton, 1999, ISMB.

Evaluation of Geometric & Probabilistic Distance Measures To Retrieve Electron Density Patterns for Protein Structure Determination

Thomas R. Ioerger, Kreshna Gopal, Tod D. Romo, 2004, IC-AI.

Database Approaches and Data Representation in Structural Bioinformatics

Thomas R. Ioerger, Kreshna Gopal, James C. Sacchettini, 2007, 2007 IEEE 7th International Symposium on BioInformatics and BioEngineering.

Crystallographic protein model-building on the web

Jacob N. Smith, Thomas R. Ioerger, Kreshna Gopal, 2007, Bioinform..

TEXTAL™: Automated Crystallographic Protein Structure Determination

Jacob N. Smith, Thomas R. Ioerger, Kreshna Gopal, 2005, AAAI.

Automated structure determination with phenix

Randy J. Read, Airlie J. McCoy, Laurent C. Storoni, 2006 .

Efficient retrieval of electron density patterns for modeling proteins by X-ray crystallography

Thomas R. Ioerger, Kreshna Gopal, Tod D. Romo, 2004, 2004 International Conference on Machine Learning and Applications, 2004. Proceedings..

Bayesian analysis of gene essentiality based on sequencing of transposon insertion libraries

Thomas R. Ioerger, James C. Sacchettini, Michael A. DeJesus, 2013, Bioinform..

Structural and Functional Analyses of the Severe Acute Respiratory Syndrome Coronavirus Endoribonuclease Nsp15*

James C. Sacchettini, J. Sacchettini, K. Bhardwaj, 2008, Journal of Biological Chemistry.

Imaging tuberculosis with endogenous β-lactamase reporter enzyme fluorescence in live mice

James C. Sacchettini, Jeffrey D. Cirillo, Jianghong Rao, 2010, Proceedings of the National Academy of Sciences.

Crystal structure of GyrA intein from Mycobacterium xenopi reveals structural basis of protein splicing

Amalio Telenti, James C. Sacchettini, William R. Jacobs, 1998, Nature Structural Biology.

The crystal structure of human hypoxanthine-guanine phosphoribosyltransferase with bound GMP

James C. Sacchettini, Yiming Xu, C. Grubmeyer, 1994, Cell.

Crystal structure of a plant catechol oxidase containing a dicopper center

James C. Sacchettini, T. Klabunde, J. Sacchettini, 1998, Nature Structural Biology.

Genome Analysis of Multi- and Extensively-Drug-Resistant Tuberculosis from KwaZulu-Natal, South Africa

Thomas R. Ioerger, James C. Sacchettini, William R. Jacobs, 2009, PloS one.

High-Throughput Sequencing Enhanced Phage Display Identifies Peptides That Bind Mycobacteria

Thomas R. Ioerger, James C. Sacchettini, Alexander Pym, 2013, PloS one.

Gene-target recognition among members of the Myc superfamily and implications for oncogenesis

Ken Chen, James C. Sacchettini, Ronald A. DePinho, 2000, Nature Genetics.

Rational design of potent human transthyretin amyloid disease inhibitors

James C. Sacchettini, H. M. Petrassi, T. Klabunde, 2000, Nature Structural Biology.

Inactivation of the inhA-Encoded Fatty Acid Synthase II (FASII) Enoyl-Acyl Carrier Protein Reductase Induces Accumulation of the FASI End Products and Cell Lysis of Mycobacterium smegmatis

James C. Sacchettini, William R. Jacobs, C. Vilchèze, 2000, Journal of bacteriology.

Therapeutic strategies for human amyloid diseases

James C. Sacchettini, J. Sacchettini, J. Kelly, 2002, Nature Reviews Drug Discovery.

Drugs versus bugs: in pursuit of the persistent predator Mycobacterium tuberculosis

James C. Sacchettini, Joel S. Freundlich, Eric J. Rubin, 2008, Nature Reviews Microbiology.

Tryptophan Biosynthesis Protects Mycobacteria from CD4 T-Cell-Mediated Killing

Thomas R. Ioerger, Curtis Huttenhower, James C. Sacchettini, 2013, Cell.

Novel Inhibitors of InhA Efficiently Kill Mycobacterium tuberculosis under Aerobic and Anaerobic Conditions

James C. Sacchettini, William R. Jacobs, David Alland, 2011, Antimicrobial Agents and Chemotherapy.

Structure of the Mycobacterium tuberculosis d-Alanine:d-Alanine Ligase, a Target of the Antituberculosis Drug d-Cycloserine

James C. Sacchettini, J. Sacchettini, J. Bruning, 2010, Antimicrobial Agents and Chemotherapy.

Use of Multiplex Allele-Specific Polymerase Chain Reaction (MAS-PCR) to Detect Multidrug-Resistant Tuberculosis in Panama

Thomas R. Ioerger, James C. Sacchettini, J. Sacchettini, 2012, PloS one.

Global Assessment of Genomic Regions Required for Growth in Mycobacterium tuberculosis

Thomas R. Ioerger, Curtis Huttenhower, James C. Sacchettini, 2012, PLoS pathogens.

Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase

James C. Sacchettini, William R. Jacobs, David G. Russell, 2000, Nature.

Mechanism of thioamide drug action against tuberculosis and leprosy

James C. Sacchettini, William R. Jacobs, Gulcin Gulten, 2007, The Journal of experimental medicine.