Shizhong Zheng

Feng Zhang, Anping Chen, Li Wu, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Dihydroartemisinin prevents liver fibrosis in bile duct ligated rats by inducing hepatic stellate cell apoptosis through modulating the PI3K/Akt pathway

Feng Zhang, Li Wu, Jiangjuan Shao, 2016, IUBMB life.

Tetramethylpyrazine inhibits angiotensin II‐induced activation of hepatic stellate cells associated with interference of platelet‐derived growth factor β receptor pathways

Feng Zhang, Yin Lu, Shizhong Zheng, 2014, The FEBS journal.

Dihydroartemisinin protects against alcoholic liver injury through alleviating hepatocyte steatosis in a farnesoid X receptor‐dependent manner

Feng Zhang, Wenxuan Xu, Jiangjuan Shao, 2017, Toxicology and applied pharmacology.

Luteolin reduces the invasive potential of malignant melanoma cells by targeting β3 integrin and the epithelial-mesenchymal transition

Yin Lu, Shizhong Zheng, Cun-si Shen, 2012, Acta Pharmacologica Sinica.

Autophagy-induced p62 accumulation is required for curcumol to regulate KLF5-mediated angiogenesis in liver sinusoidal endothelial cells.

Feng Zhang, P. Cao, Anping Chen, 2021, Toxicology.

N6-methyladenosine modification regulates ferroptosis through autophagy signaling pathway in hepatic stellate cells

Feng Zhang, Anping Chen, Feng Zhang, 2021, Redox biology.

Curcumin eliminates leptin's effects on hepatic stellate cell activation via interrupting leptin signaling.

Anping Chen, Shizhong Zheng, Youcai Tang, 2009, Endocrinology.

Dihydroartemisinin Induces Ferroptosis in HCC by Promoting the Formation of PEBP1/15-LO

Feng Zhang, Yuxin Zhang, Feng Zhang, 2021, Oxidative medicine and cellular longevity.

Curcumin regulates cell fate and metabolism by inhibiting hedgehog signaling in hepatic stellate cells

Feng Zhang, Yin Lu, Shizhong Zheng, 2015, Laboratory Investigation.

Inhibition of hypoxia-induced epithelial mesenchymal transition by luteolin in non-small cell lung cancer cells.

Yin Lu, Shizhong Zheng, Yu-ping Liu, 2012, Molecular medicine reports.

Regulation of hepatic stellate cell contraction and cirrhotic portal hypertension by Wnt/β‐catenin signalling via interaction with Gli1

Feng Zhang, Anping Chen, Shijun Wang, 2020, British journal of pharmacology.

ROS-JNK1/2-dependent activation of autophagy is required for the induction of anti-inflammatory effect of dihydroartemisinin in liver fibrosis.

Jiangjuan Shao, Zili Zhang, Shizhong Zheng, 2016, Free radical biology & medicine.

Effect of aqueous extracts of several kinds of herbs on human platelet aggregation and expression of P-selectin in vitro

Yin Lu, L. Zeng, F. Zhang, 2015, Chinese Journal of Integrative Medicine.

Inhibition of ASCT2 induces hepatic stellate cell senescence with modified proinflammatory secretome through an IL-1α/NF-κB feedback pathway to inhibit liver fibrosis

Feng Zhang, Shijun Wang, Feixia Wang, 2022, Acta pharmaceutica Sinica. B.

Curcumin attenuates ethanol‐induced hepatic steatosis through modulating Nrf2/FXR signaling in hepatocytes

Feng Zhang, Yin Lu, Li Wu, 2015, IUBMB life.

Paeonol inhibits hepatic fibrogenesis via disrupting nuclear factor‐κB pathway in activated stellate cells: In vivo and in vitro studies

Feng Zhang, Yin Lu, Shizhong Zheng, 2013, Journal of Gastroenterology and Hepatology.

Endoplasmic reticulum stress and protein degradation in chronic liver disease.

Feng Zhang, Anping Chen, Shijun Wang, 2020, Pharmacological research.

Holothurian Glycosaminoglycan Inhibits Metastasis and Thrombosis via Targeting of Nuclear Factor-κB/Tissue Factor/Factor Xa Pathway in Melanoma B16F10 Cells

Daohai Zhang, Xiang Gao, Yin Lu, 2013, PloS one.

Dihydroartemisinin restricts hepatic stellate cell contraction via an FXR‐S1PR2‐dependent mechanism

Feng Zhang, Wenxuan Xu, Jiangjuan Shao, 2016, IUBMB life.

LncRNA-H19 induces hepatic stellate cell activation via upregulating alcohol dehydrogenase III-mediated retinoic acid signals.

Feng Zhang, Anping Chen, J. Kai, 2020, International immunopharmacology.

Crosstalk Between Autophagy and Innate Immunity: A Pivotal Role in Hepatic Fibrosis

Feng Zhang, Feixia Wang, Zhanghao Li, 2022, Frontiers in Pharmacology.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

Nrf2 Knockdown Disrupts the Protective Effect of Curcumin on Alcohol-Induced Hepatocyte Necroptosis.

Feng Zhang, Wenxuan Xu, Jiangjuan Shao, 2016, Molecular pharmaceutics.

Ligand Activation of PPARγ by Ligustrazine Suppresses Pericyte Functions of Hepatic Stellate Cells via SMRT-Mediated Transrepression of HIF-1α

Feng Zhang, Shuai Lu, Anping Chen, 2018, Theranostics.

Canonical hedgehog signalling regulates hepatic stellate cell‐mediated angiogenesis in liver fibrosis

Feng Zhang, Anping Chen, Li Wu, 2017, British journal of pharmacology.

Pulmonary , gastrointestinal and urogenital pharmacology Curcumin modulates cannabinoid receptors in liver fi brosis in vivo and inhibits extracellular matrix expression in hepatic stellate cells by suppressing cannabinoid receptor type-1 in vitro

Yan Zhang, Wen-Chiu Ni, Zili Zhang, 2013 .

de novo synthesis of glutathione is a prerequisite for curcumin to inhibit HSC activation

Anping Chen, Shizhong Zheng, F. Yu-mei, 2008 .

P53‐dependent induction of ferroptosis is required for artemether to alleviate carbon tetrachloride‐induced liver fibrosis and hepatic stellate cell activation

Feng Zhang, Anping Chen, Feixia Wang, 2018, IUBMB life.

Curcumin blunts epithelial-mesenchymal transition of hepatocytes to alleviate hepatic fibrosis through regulating oxidative stress and autophagy

Feng Zhang, P. Cao, Li-ping Chen, 2020, Redox biology.

Oroxylin A prevents alcohol-induced hepatic steatosis through inhibition of hypoxia inducible factor 1alpha.

Feng Zhang, Q. Guo, Anping Chen, 2018, Chemico-biological interactions.

Magnesium isoglycyrrhizinate promotes the activated hepatic stellate cells apoptosis via endoplasmic reticulum stress and ameliorates fibrogenesis in vitro and in vivo

Feng Zhang, Anping Chen, Feixia Wang, 2017, BioFactors.

HIF-1α-upregulated lncRNA-H19 regulates lipid droplet metabolism through the AMPKα pathway in hepatic stellate cells.

Feng Zhang, Anping Chen, J. Kai, 2020, Life sciences.

Oroxylin A regulates the turnover of lipid droplet via downregulating adipose triglyceride lipase (ATGL) in hepatic stellate cells.

Feng Zhang, Anping Chen, Shijun Wang, 2019, Life sciences.

Curcumol induces RIPK1/RIPK3 complex-dependent necroptosis via JNK1/2-ROS signaling in hepatic stellate cells

Feng Zhang, Q. Guo, Anping Chen, 2018, Redox biology.

Oroxylin A inhibits ethanol‐induced hepatocyte senescence via YAP pathway

Feng Zhang, Q. Guo, Anping Chen, 2018, Cell proliferation.

Autophagy regulates turnover of lipid droplets via ROS-dependent Rab25 activation in hepatic stellate cell

Feng Zhang, Anping Chen, Jiangjuan Shao, 2016, Redox biology.

Curcumol Suppresses CCF-Mediated Hepatocyte Senescence Through Blocking LC3B–Lamin B1 Interaction in Alcoholic Fatty Liver Disease

Mingyue Ma, Shizhong Zheng, Shuguo Zheng, 2022, Frontiers in Pharmacology.

Ligustrazine attenuates oxidative stress-induced activation of hepatic stellate cells by interrupting platelet-derived growth factor-β receptor-mediated ERK and p38 pathways.

Feng Zhang, Yin Lu, Shizhong Zheng, 2012, Toxicology and applied pharmacology.

Injectable caltrop fruit saponin protects against ischemia-reperfusion injury in rat brain.

Yin Lu, Shizhong Zheng, Aiyun Wang, 2011, The American journal of Chinese medicine.

Dihydroartemisinin alleviates bile duct ligation-induced liver fibrosis and hepatic stellate cell activation by interfering with the PDGF-βR/ERK signaling pathway.

Li Wu, Jiangjuan Shao, Shizhong Zheng, 2016, International immunopharmacology.

Hepatic stellate cell interferes with NK cell regulation of fibrogenesis via curcumin induced senescence of hepatic stellate cell.

Feng Zhang, Jingjing Huang, Anping Chen, 2017, Cellular signalling.

Ligustrazine prevents alcohol-induced liver injury by attenuating hepatic steatosis and oxidative stress.

Feng Zhang, Yin Lu, Li Wu, 2015, International immunopharmacology.

Tetramethylpyrazine reduces glucose and insulin-induced activation of hepatic stellate cells by inhibiting insulin receptor-mediated PI3K/AKT and ERK pathways

Feng Zhang, Yin Lu, Zili Zhang, 2014, Molecular and Cellular Endocrinology.

Acupuncture Combined with Curcumin Disrupts Platelet-Derived Growth Factor β Receptor/Extracellular Signal-Regulated Kinase Signalling and Stimulates Extracellular Matrix Degradation in Carbon Tetrachloride-Induced Hepatic Fibrosis in Rats

Feng Zhang, Yin Lu, Zili Zhang, 2012, Acupuncture in medicine : journal of the British Medical Acupuncture Society.

Acupuncture Combined with Curcumin Attenuates Carbon Tetrachloride-Induced Hepatic Fibrosis in Rats

Feng Zhang, Yin Lu, Shizhong Zheng, 2012, Acupuncture in medicine : journal of the British Medical Acupuncture Society.

Curcumin attenuates the effects of insulin on stimulating hepatic stellate cell activation by interrupting insulin signaling and attenuating oxidative stress

Jianguo Lin, Anping Chen, Shizhong Zheng, 2009, Laboratory Investigation.

De novo synthesis of glutathione is a prerequisite for curcumin to inhibit hepatic stellate cell (HSC) activation.

Anping Chen, Shizhong Zheng, F. Yu-mei, 2007, Free radical biology & medicine.

Periostin in chronic liver diseases: Current research and future perspectives

Feng Zhang, Q. Guo, Anping Chen, 2019, Life sciences.

Dihydroartemisinin counteracts fibrotic portal hypertension via farnesoid X receptor‐dependent inhibition of hepatic stellate cell contraction

Feng Zhang, Wenxuan Xu, Jiangjuan Shao, 2017, The FEBS journal.

m6A methylation is required for dihydroartemisinin to alleviate liver fibrosis by inducing ferroptosis in hepatic stellate cells.

Feng Zhang, Shijun Wang, Anping Chen, 2022, Free radical biology & medicine.

Dihydroartemisinin attenuates alcoholic fatty liver through regulation of lipin‐1 signaling

Feng Zhang, Jiangjuan Shao, Shizhong Zheng, 2019, IUBMB life.

Oroxylin A induces apoptosis of activated hepatic stellate cells through endoplasmic reticulum stress

Feng Zhang, Q. Guo, Shijun Wang, 2019, Apoptosis.

Diallyl trisulfide attenuates ethanol-induced hepatic steatosis by inhibiting oxidative stress and apoptosis.

Feng Zhang, Li Wu, Jiangjuan Shao, 2016, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Tetramethylpyrazine prevents ethanol-induced hepatocyte injury via activation of nuclear factor erythroid 2-related factor 2.

Feng Zhang, Yin Lu, Li Wu, 2015, Life sciences.

Comparative effects of Hirudo, Frankincense and Motherwort on the inhibition of blood platelet aggregation and P-selectin secretion

Yin Lu, Shizhong Zheng, Aiyun Wang, 2012 .

ROS-dependent inhibition of the PI3K/Akt/mTOR signaling is required for Oroxylin A to exert anti-inflammatory activity in liver fibrosis.

Feng Zhang, Anping Chen, Yujia Li, 2020, International immunopharmacology.

Cryptotanshinone Activates p38/JNK and Inhibits Erk1/2 Leading to Caspase-Independent Cell Death in Tumor Cells

Y. Odaka, Yan Luo, T. Shen, 2012, Cancer Prevention Research.

Curcumol alleviates liver fibrosis by inducing endoplasmic reticulum stress-mediated necroptosis of hepatic stellate cells through Sirt1/NICD pathway

Feng Zhang, Shijun Wang, Zhanghao Li, 2022, PeerJ.

Modification of lysine deacetylation regulates curcumol‐induced necroptosis through autophagy in hepatic stellate cells

Feng Zhang, Anping Chen, J. Kai, 2022, Phytotherapy research : PTR.

Iron Regulatory Protein 2 is required for artemether -mediated anti-hepatic fibrosis through ferroptosis pathway.

Feng Zhang, Anping Chen, Shijun Wang, 2020, Free radical biology & medicine.

Liver regeneration in traditional Chinese medicine: advances and challenges

Feng Zhang, Shijun Wang, Feixia Wang, 2020, Regenerative medicine research.

Docosahexaenoic acid attenuates carbon tetrachloride‐induced hepatic fibrosis in rats

Feng Zhang, Bi-hong Hong, Kai-kai Bai, 2017, International immunopharmacology.

Diallyl trisulfide attenuates carbon tetrachloride-caused liver injury and fibrogenesis and reduces hepatic oxidative stress in rats

Feng Zhang, Yin Lu, Shizhong Zheng, 2014, Naunyn-Schmiedeberg's Archives of Pharmacology.

Carboxylated nanodiamond-mediated NH2-PLGA nanoparticle-encapsulated fig polysaccharides for strongly enhanced immune responses in vitro and in vivo.

Zhenhuan Guo, Dan Li, Shizhong Zheng, 2020, International journal of biological macromolecules.

Dihydroartemisinin inhibits ER stress-mediated mitochondrial pathway to attenuate hepatocyte lipoapoptosis via blocking the activation of the PI3K/Akt pathway.

Feng Zhang, Anping Chen, J. Kai, 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Curcumin inhibits cobalt chloride-induced epithelial-to-mesenchymal transition associated with interference with TGF-β/Smad signaling in hepatocytes

Feng Zhang, Yin Lu, Li Wu, 2015, Laboratory Investigation.

Naringenin is a Potential Immunomodulator for Inhibiting Liver Fibrosis by Inhibiting the cGAS-STING Pathway

Y. Li, Feng Zhang, Yang Li, 2022, Journal of clinical and translational hepatology.

Oroxylin a promotes PGC-1α/Mfn2 signaling to attenuate hepatocyte pyroptosis via blocking mitochondrial ROS in alcoholic liver disease.

Feng Zhang, Anping Chen, J. Kai, 2020, Free radical biology & medicine.

Tetramethylpyrazine attenuates carbon tetrachloride-caused liver injury and fibrogenesis and reduces hepatic angiogenesis in rats.

Feng Zhang, Jiangjuan Shao, Zili Zhang, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Tetramethylpyrazine attenuates sinusoidal angiogenesis via inhibition of hedgehog signaling in liver fibrosis

Feng Zhang, Anping Chen, Jiangjuan Shao, 2017, IUBMB life.

Inhibition of vascular endothelial growth factor-mediated angiogenesis involved in reproductive toxicity induced by sesquiterpenoids of Curcuma zedoaria in rats.

Shile Huang, Juan Li, Yin Lu, 2013, Reproductive toxicology.

Diallyl Trisulfide Suppresses Oxidative Stress-Induced Activation of Hepatic Stellate Cells through Production of Hydrogen Sulfide

Feng Zhang, Anping Chen, Li Wu, 2017, Oxidative medicine and cellular longevity.

Cryptotanshinone Inhibits Lymphatic Endothelial Cell Tube Formation by Suppressing VEGFR-3/ERK and Small GTPase Pathways

Yan Luo, T. Shen, Hongyu Zhou, 2011, Cancer Prevention Research.

Chemopreventive efficacy of menthol on carcinogen-induced cutaneous carcinoma through inhibition of inflammation and oxidative stress in mice.

Yuzhu Cao, Hongyan Wu, Yin Lu, 2015, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Update on implications and mechanisms of angiogenesis in liver fibrosis

Feng Zhang, Yin Lu, Zili Zhang, 2015, Hepatology research : the official journal of the Japan Society of Hepatology.

Peroxisome proliferator-activated receptor-γ cross-regulation of signaling events implicated in liver fibrogenesis.

Feng Zhang, Yin Lu, Shizhong Zheng, 2012, Cellular signalling.

Curcumin Protects the Rat Liver from CCl4-Caused Injury and Fibrogenesis by Attenuating Oxidative Stress and Suppressing Inflammation

Jianguo Lin, J. Ryerse, Anping Chen, 2008, Molecular Pharmacology.

Efficacy of Ethanol Extract of Fructus lycii and Its Constituents Lutein/Zeaxanthin in Protecting Retinal Pigment Epithelium Cells against Oxidative Stress: In Vivo and In Vitro Models of Age-Related Macular Degeneration

Shizhong Zheng, Xinrong Xu, Bing-Lin Huang, 2013, Journal of ophthalmology.

Ligustrazine inhibits B16F10 melanoma metastasis and suppresses angiogenesis induced by Vascular Endothelial Growth Factor.

Yin Lu, Shizhong Zheng, M. Gao, 2009, Biochemical and biophysical research communications.

Curcumin attenuates angiogenesis in liver fibrosis and inhibits angiogenic properties of hepatic stellate cells

Feng Zhang, Yin Lu, Zili Zhang, 2014, Journal of cellular and molecular medicine.

Epigallocatechin-3-gallate Inhibits Growth of Activated Hepatic Stellate Cells by Enhancing the Capacity of Glutathione Synthesis

Shelly C. Lu, Anping Chen, Shizhong Zheng, 2008, Molecular Pharmacology.

The interruption of the PDGF and EGF signaling pathways by curcumin stimulates gene expression of PPARγ in rat activated hepatic stellate cell in vitro

Jianguo Lin, Anping Chen, Shizhong Zheng, 2007, Laboratory Investigation.

The antifibrogenic effect of (−)-epigallocatechin gallate results from the induction of de novo synthesis of glutathione in passaged rat hepatic stellate cells

Anping Chen, Shizhong Zheng, Yajun Zhou, 2006, Laboratory Investigation.

The update on transcriptional regulation of autophagy in normal and pathologic cells: A novel therapeutic target.

Feng Zhang, Yin Lu, Li Wu, 2015, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

A novel lncRNA PLK4 up‐regulated by talazoparib represses hepatocellular carcinoma progression by promoting YAP‐mediated cell senescence

Feng Zhang, Anping Chen, Shijun Wang, 2020, Journal of cellular and molecular medicine.

Qingchang Wenzhong Decoction reduce ulcerative colitis in mice by inhibiting Th17 lymphocyte differentiation.

Feng Zhang, Yang Li, Zhanghao Li, 2022, Phytomedicine : international journal of phytotherapy and phytopharmacology.

RNA-binding protein ZFP36/TTP protects against ferroptosis by regulating autophagy signaling pathway in hepatic stellate cells.

Feng Zhang, Anping Chen, Yujia Li, 2019, Autophagy.

Dihydroartemisinin regulates lipid droplet metabolism in hepatic stellate cells by inhibiting lncRNA-H19-induced AMPK signal.

Feng Zhang, Anping Chen, Shijun Wang, 2021, Biochemical Pharmacology.

Activation of Fas death receptor pathway and Bid in hepatocytes is involved in saikosaponin D induction of hepatotoxicity.

Feng Zhang, Yin Lu, Li Wu, 2016, Environmental toxicology and pharmacology.

The BRD7-P53-SLC25A28 axis regulates ferroptosis in hepatic stellate cells

Feng Zhang, P. Cao, Anping Chen, 2020, Redox biology.

Xanthatin Induces G2/M Cell Cycle Arrest and Apoptosis in Human Gastric Carcinoma MKN-45 Cells

Feng Zhang, Yu Wu, Yin Lu, 2012, Planta Medica.

PKM2 regulates hepatocellular carcinoma cell epithelial-mesenchymal transition and migration upon EGFR activation.

Yin Lu, Hong-yan Wu, Zhaoguo Liu, 2014, Asian Pacific journal of cancer prevention : APJCP.

Tetramethylpyrazine reduces inflammation in liver fibrosis and inhibits inflammatory cytokine expression in hepatic stellate cells by modulating NLRP3 inflammasome pathway

Feng Zhang, Yin Lu, Shizhong Zheng, 2015, IUBMB life.

Saikosaponin D disrupts platelet-derived growth factor-β receptor/p38 pathway leading to mitochondrial apoptosis in human LO2 hepatocyte cells: a potential mechanism of hepatotoxicity.

Feng Zhang, Shizhong Zheng, Aiyun Wang, 2013, Chemico-biological interactions.

Clearance of activated stellate cells for hepatic fibrosis regression: molecular basis and translational potential.

Feng Zhang, Yin Lu, Zili Zhang, 2013, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Activation of ferritinophagy is required for the RNA-binding protein ELAVL1/HuR to regulate ferroptosis in hepatic stellate cells

Feng Zhang, Anping Chen, Jiangjuan Shao, 2018, Autophagy.

Diallyl trisulfide protects against ethanol-induced oxidative stress and apoptosis via a hydrogen sulfide-mediated mechanism.

Li Wu, Jiangjuan Shao, Shizhong Zheng, 2016, International immunopharmacology.

Oroxylin A regulates cGAS DNA hypermethylation induced by methionine metabolism to promote HSC senescence.

Ying Sun, Feng Zhang, Yang Li, 2022, Pharmacological research.

Dll4-Notch signaling in regulation of tumor angiogenesis

Yin Lu, Zhaoguo Liu, Shizhong Zheng, 2014, Journal of Cancer Research and Clinical Oncology.

Da-Huang-Fu-Zi-Tang attenuates liver injury in rats with severe acute pancreatitis.

Baochang Cai, Li Wu, Shizhong Zheng, 2013, Journal of ethnopharmacology.

Peroxisome proliferator-activated receptor-&ggr; interrupts angiogenic signal transduction by transrepression of platelet-derived growth factor-&bgr; receptor in hepatic stellate cells

Feng Zhang, Yin Lu, Shizhong Zheng, 2014, Journal of Cell Science.

Peroxisome proliferator-activated receptor-c interrupts angiogenic signal transduction by transrepression of platelet-derived growth factor-b receptor in hepatic stellate cells

Feng Zhang, Yin Lu, Shizhong Zheng, 2013 .

Perilipin 5 and liver fatty acid binding protein function to restore quiescence in mouse hepatic stellate cells[S]

A. Attie, D. Bernlohr, W. Blaner, 2018, Journal of Lipid Research.

Feng Zhang, Zijian Guo, Xiaoyong Wang, 2019, Cell Communication and Signaling.

Yi-Qi-Jian-Pi formula modulates the PI3K/AKT signaling pathway to attenuate acute-on-chronic liver failure by suppressing hypoxic injury and apoptosis in vivo and in vitro.

Feng Zhang, L-M Tang, Feixia Wang, 2021, Journal of ethnopharmacology.

Novel copper complex CTB regulates methionine cycle induced TERT hypomethylation to promote HCC cells senescence via mitochondrial SLC25A26

Feng Zhang, Zijian Guo, Xiaoyong Wang, 2020, Cell Death & Disease.

Activation of autophagy is required for Oroxylin A to alleviate carbon tetrachloride‐induced liver fibrosis and hepatic stellate cell activation

Feng Zhang, Anping Chen, Jiangjuan Shao, 2018, International immunopharmacology.

Methionine metabolism in chronic liver diseases: an update on molecular mechanism and therapeutic implication

Feng Zhang, Min Hong, Feixia Wang, 2020, Signal Transduction and Targeted Therapy.

Tetramethylpyrazine induces G0/G1 cell cycle arrest and stimulates mitochondrial-mediated and caspase-dependent apoptosis through modulating ERK/p53 signaling in hepatic stellate cells in vitro

Feng Zhang, Yin Lu, Zili Zhang, 2013, Apoptosis.

Ligustrazine disrupts lipopolysaccharide-activated NLRP3 inflammasome pathway associated with inhibition of Toll-like receptor 4 in hepatocytes.

Feng Zhang, Yin Lu, Li Wu, 2016, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Blockade of glycolysis-dependent contraction by oroxylin a via inhibition of lactate dehydrogenase-a in hepatic stellate cells

Feng Zhang, Q. Guo, Anping Chen, 2019, Cell Communication and Signaling.

Danshensu has anti-tumor activity in B16F10 melanoma by inhibiting angiogenesis and tumor cell invasion.

Zhiguang Sun, Yin Lu, Shizhong Zheng, 2010, European journal of pharmacology.

Acidic mucopolysaccharide from holothuria leucospilota has antitumor effect by inhibiting angiogenesis and tumor cell invasion in vivo and in vitro

Yin Lu, Shizhong Zheng, M. Gao, 2009, Cancer biology & therapy.

Paeonol inhibits B16F10 melanoma metastasis In vitro and In Vivo via disrupting proinflammatory cytokines‐mediated NF‐κB and STAT3 pathways

Feng Zhang, Yuzhu Cao, Yin Lu, 2015, IUBMB life.

Oroxylin A prevents angiogenesis of LSECs in liver fibrosis via inhibition of YAP/HIF‐1α signaling

Feng Zhang, Q. Guo, Anping Chen, 2018, Journal of cellular biochemistry.

Cryptotanshinone has diverse effects on cell cycle events in melanoma cell lines with different metastatic capacity

Zhiguang Sun, Xiang Gao, Yin Lu, 2011, Cancer Chemotherapy and Pharmacology.

The effects of epigenetic modification on the occurrence and progression of liver diseases and the involved mechanism

Feng Zhang, Li-ping Chen, Zili Zhang, 2020, Expert review of gastroenterology & hepatology.

Lipophagy and liver disease: New perspectives to better understanding and therapy.

Yifan Chen, Feng Zhang, Anping Chen, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Blockade of hedgehog pathway is required for the protective effects of magnesium isoglycyrrhizinate against ethanol‐induced hepatocyte steatosis and apoptosis

Feng Zhang, Anping Chen, Wenxuan Xu, 2017, IUBMB life.

Curcumol attenuates liver sinusoidal endothelial cell angiogenesis via regulating Glis‐PROX1‐HIF‐1α in liver fibrosis

Feng Zhang, Anping Chen, J. Kai, 2020, Cell proliferation.

Curcumin inhibits aerobic glycolysis in hepatic stellate cells associated with activation of adenosine monophosphate‐activated protein kinase

Feng Zhang, Yin Lu, Li Wu, 2016, IUBMB life.

Nrf2 induces lipocyte phenotype via a SOCS3‐dependent negative feedback loop on JAK2/STAT3 signaling in hepatic stellate cells

Feng Zhang, Anping Chen, Wenxuan Xu, 2017, International immunopharmacology.

Blockade of glycolysis-dependent contraction by oroxylin a via inhibition of lactate dehydrogenase-a in hepatic stellate cells

Feng Zhang, Q. Guo, Anping Chen, 2019, Cell Communication and Signaling.

Biodegradable Hypocrellin B nanoparticles coated with neutrophil membranes for hepatocellular carcinoma photodynamics therapy effectively via JUNB/ROS signaling.

Dan Li, Feixia Wang, Shizhong Zheng, 2021, International immunopharmacology.

Docosahexaenoic acid inhibits hepatic stellate cell activation to attenuate liver fibrosis in a PPARγ-dependent manner.

Feng Zhang, Junde Chen, Bi-hong Hong, 2019, International immunopharmacology.

Phenolcarboxylic acids from medicinal herbs exert anticancer effects through disruption of COX-2 activity.

Yin Lu, Shizhong Zheng, Aiyun Wang, 2014, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Abstract 3798: Cryptotanshinone inhibits lymphatic endothelial cell tube formation by suppressing VEGFR-3/ERK and small GTPase pathways

Yan Luo, T. Shen, Hongyu Zhou, 2012 .

Regulation of ferroptosis by ncRNA: A new direction

Feng Zhang, Anping Chen, Baoyu Liang, 2020 .

Oroxylin A activates ferritinophagy to induce hepatic stellate cell senescence against hepatic fibrosis by regulating cGAS-STING pathway.

Ying Sun, Feng Zhang, Yuxin Zhang, 2023, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Dihydroartemisinin alleviates hepatic fibrosis through inducing ferroptosis in hepatic stellate cells

Feng Zhang, Zonghui Wei, Anping Chen, 2021, BioFactors.

Peroxisome proliferator-activated receptor-γ as a therapeutic target for hepatic fibrosis: from bench to bedside

Feng Zhang, Yin Lu, Shizhong Zheng, 2012, Cellular and Molecular Life Sciences.

Blockade of periostin-dependent migration and adhesion by curcumol via inhibition of nuclear factor kappa β signaling in hepatic stellate cells.

Feng Zhang, Anping Chen, Shijun Wang, 2020, Toxicology.

Peripheral T lymphocytes predict the severity and prognosis in patients with HBV-related acute-on-chronic liver failure

Feixia Wang, Jiangjuan Shao, Shanzhong Tan, 2020, Medicine.

Combined therapy with ligustrazine and paeonol mitigates hepatic fibrosis through destroying mitochondrial integrity of stellate cell.

Feng Zhang, Li-ping Chen, Zili Zhang, 2020, American journal of translational research.

Nrf2 knockdown attenuates the ameliorative effects of ligustrazine on hepatic fibrosis by targeting hepatic stellate cell transdifferentiation.

Feng Zhang, Wenxuan Xu, Jiangjuan Shao, 2016, Toxicology.

Tranferrine-modified Cancer cell member coating Hypocrellin B derived Nanomaterials for enhanced photodynamic therapy efficacy in hepatocellular carcinoma

Zhenhuan Guo, Kai Zhao, Shizhong Zheng, 2021 .

Curcumol inhibits KLF5-dependent angiogenesis by blocking the ROS/ERK signaling in liver sinusoidal endothelial cells.

Feng Zhang, P. Cao, Anping Chen, 2020, Life sciences.

Effect of Emodin on Endoplasmic Reticulum Stress in Rats with Severe Acute Pancreatitis

Baochang Cai, Li Wu, Shizhong Zheng, 2013, Inflammation.

Dihydroartemisinin inhibits the activation and proliferation of hepatic stellate cells by regulating miR-29b-3p

Yi Ji, Shizhong Zheng, J. Dai, 2023, International journal of molecular medicine.

Blockade of KLF5/LDH-A feedback loop contributes to Curcumol inhibition of sinusoidal endothelial cell glycolysis and mitigation of liver fibrosis.

Feng Zhang, Jiangjuan Shao, Zili Zhang, 2023, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Disruption of transforming growth factor-β signaling by curcumin induces gene expression of peroxisome proliferator-activated receptor-γ in rat hepatic stellate cells

Anping Chen, Shizhong Zheng, Anping Chen, 2007 .

β‐Elemene induces apoptosis by activating the P53 pathway in human hypertrophic scar fibroblasts

Jianzhou Ye, Yujia Li, Shizhong Zheng, 2022, IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology.

m6A methylation-induced NR1D1 ablation disrupts the HSC circadian clock and promotes hepatic fibrosis.

Feng Zhang, Feixia Wang, Jiangjuan Shao, 2023, Pharmacological research.

Curcumin raises lipid content by Wnt pathway in hepatic stellate cell.

Feng Zhang, Yin Lu, Li Wu, 2016, The Journal of surgical research.

The mechanism research on the anti‐liver fibrosis of emodin based on network pharmacology

Feng Zhang, Anping Chen, Feixia Wang, 2021, IUBMB life.

Nrf2 activation is required for curcumin to induce lipocyte phenotype in hepatic stellate cells.

Wenxuan Xu, Shizhong Zheng, Chunfeng Lu, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Emodin promotes hepatic stellate cell senescence and alleviates liver fibrosis via a nuclear receptor (Nur77)‐mediated epigenetic regulation of glutaminase 1

Feng Zhang, Anping Chen, Feixia Wang, 2023, British journal of pharmacology.

Activation of PPARγ/P53 signaling is required for curcumin to induce hepatic stellate cell senescence

Qin Chen, Feng Zhang, F. Zhang, 2016, Cell Death and Disease.

Disruption of transforming growth factor-beta signaling by curcumin induces gene expression of peroxisome proliferator-activated receptor-gamma in rat hepatic stellate cells.

Anping Chen, Shizhong Zheng, Anping Chen, 2007, American journal of physiology. Gastrointestinal and liver physiology.

Diallyl trisulfide attenuates carbon tetrachloride-caused liver injury and fibrogenesis and reduces hepatic oxidative stress in rats

Feng Zhang, Yin Lu, Shizhong Zheng, 2014, Naunyn-Schmiedeberg's Archives of Pharmacology.

Induction of DNMT1-dependent demethylation of SHP-1 by the natural flavonoid compound Baicalein overcame Imatinib-resistance in CML CD34+ cells

Feng Zhang, Yujia Li, Zili Zhang, 2023, Cell Communication and Signaling.

Interaction between autophagy and senescence is required for dihydroartemisinin to alleviate liver fibrosis

Feng Zhang, Anping Chen, Jiangjuan Shao, 2017, Cell Death & Disease.

Lipophagy and liver disease: New perspectives to better understanding and therapy.

Yifan Chen, Feng Zhang, Anping Chen, 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Curcumin modulates cannabinoid receptors in liver fibrosis in vivo and inhibits extracellular matrix expression in hepatic stellate cells by suppressing cannabinoid receptor type-1 in vitro.

Zili Zhang, Shizhong Zheng, Desong Kong, 2013, European journal of pharmacology.

Tetramethylpyrazine reduces glucose and insulin-induced activation of hepatic stellate cells by inhibiting insulin receptor-mediated PI3K/AKT and ERK pathways

Feng Zhang, Yin Lu, Zili Zhang, 2014, Molecular and Cellular Endocrinology.

Evaluate the effect of licorice on anti-liver fibrosis: a systematic review and meta-analysis

Feng Zhang, Zili Zhang, Shizhong Zheng, 2022, Food Science and Technology.

Tetramethylpyrazine attenuates carbon tetrachloride-caused liver injury and fibrogenesis and reduces hepatic angiogenesis in rats.

Feng Zhang, Jiangjuan Shao, Zili Zhang, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Nrf2 Activation Is Required for Ligustrazine to Inhibit Hepatic Steatosis in Alcohol-Preferring Mice and Hepatocytes

Feng Zhang, Anping Chen, Wenxuan Xu, 2017, Toxicological sciences : an official journal of the Society of Toxicology.

Xanthatin Induces G2/M Cell Cycle Arrest and Apoptosis in Human Gastric Carcinoma MKN-45 Cells

Feng Zhang, Yu Wu, Yin Lu, 2012, Planta Medica.

COVID‐19‐associated liver injury: Adding fuel to the flame

Feng Zhang, Yujia Li, Jiangjuan Shao, 2023, Cell biochemistry and function.

Perilipin 5 and liver fatty acid binding protein function to restore quiescence in mouse hepatic stellate cells[S]

A. Attie, D. Bernlohr, W. Blaner, 2018, Journal of Lipid Research.

Artesunate Induces Ferroptosis in Hepatic Stellate Cells and Alleviates Liver Fibrosis via the ROCK1/ATF3 Axis

Feng Zhang, Yujia Li, Jiangjuan Shao, 2023, Journal of clinical and translational hepatology.

Autophagy activation is required for N6-methyladenosine modification to regulate ferroptosis in hepatocellular carcinoma

Feng Zhang, Yujia Li, Jiangjuan Shao, 2023, Redox biology.

Inhibition of vascular endothelial growth factor-mediated angiogenesis involved in reproductive toxicity induced by sesquiterpenoids of Curcuma zedoaria in rats.

Shile Huang, Juan Li, Yin Lu, 2013, Reproductive toxicology.

O-GlcNAcylation Coordinates Glutaminolysis by Regulating the Stability and Membrane Trafficking of ASCT2 in Hepatic Stellate Cells

Feng Zhang, Feixia Wang, Zhanghao Li, 2022, Journal of clinical and translational hepatology.

Oxidative stress induces ferroptosis in tendon stem cells by regulating mitophagy through cGAS-STING pathway.

Feixia Wang, Jiangjuan Shao, Zili Zhang, 2024, International immunopharmacology.