Xiwen Xiong

发表

NAMPT-mediated NAD+ biosynthesis suppresses activation of hepatic stellate cells and protects against CCl4-induced liver fibrosis in mice

Lin Xu, Chenyan Yang, Jie Ma, 2021, Human & experimental toxicology.

Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cells

Robert A. Harris, X. Tong, Pengfei Wu, 2015, Diabetologia.

Overexpression of NRK1 ameliorates diet- and age-induced hepatic steatosis and insulin resistance.

Qingzhi Wang, Xiwen Xiong, Bin Zhao, 2018, Biochemical and biophysical research communications.

A novel Phex mutation with defective glycosylation causes hypophosphatemia and rickets in mice.

Jing Zhao, Xiang Gao, Jing Zhao, 2008, Journal of biomedical science.

The Autophagy-related Gene 14 (Atg14) Is Regulated by Forkhead Box O Transcription Factors and Circadian Rhythms and Plays a Critical Role in Hepatic Autophagy and Lipid Metabolism*

R. DePinho, X. C. Dong, Xiwen Xiong, 2012, The Journal of Biological Chemistry.

Prediction and Validation of Transcription Factors Modulating the Expression of Sestrin3 Gene Using an Integrated Computational and Experimental Approach

S. Janga, S. Liangpunsakul, X. C. Dong, 2016, PloS one.

Fabp 4-Cre-mediated Sirt 6 deletion impairs adipose tissue function 1 and metabolic homeostasis in mice 2 Running title : Sirt 6 function in adipose tissue 3

Rui Fan, X. C. Dong, Xiwen Xiong, 2017 .

Fabp4-Cre-mediated Sirt6 deletion impairs adipose tissue function and metabolic homeostasis in mice.

X. C. Dong, Xiwen Xiong, Yang Zhang, 2017, The Journal of endocrinology.

SIRT6 protects against palmitate-induced pancreatic β-cell dysfunction and apoptosis.

Yang Zhang, X. C. Dong, Xiaoyan Pan, 2016, The Journal of endocrinology.

FoxO3 Transcription Factor and Sirt6 Deacetylase Regulate Low Density Lipoprotein (LDL)-cholesterol Homeostasis via Control of the Proprotein Convertase Subtilisin/Kexin Type 9 (Pcsk9) Gene Expression*

R. DePinho, C. Deng, X. C. Dong, 2013, The Journal of Biological Chemistry.

Pharmacological promotion of autophagy alleviates steatosis and injury in alcoholic and non-alcoholic fatty liver conditions in mice.

X. Chen, Xiao-Ming Yin, X. Dong, 2013, Journal of hepatology.

Mitochondrial protein IF1 is a potential regulator of glucagon-like peptide (GLP-1) secretion function of the mouse intestine

Jianping Ye, Xiaoying Zhang, Hui Wang, 2021, Acta pharmaceutica Sinica. B.

Inhibitor of Differentiation-2 Protein Ameliorates DSS-Induced Ulcerative Colitis by Inhibiting NF-κB Activation in Neutrophils

Yichun Wang, Jie Ren, Xiwen Xiong, 2021, Frontiers in Immunology.

The epigenetic regulator SIRT6 protects the liver from alcohol-induced tissue injury by reducing oxidative stress in mice.

X. Dong, J. Wan, Zhaoli Sun, 2019, Journal of hepatology.

Depdc5 deficiency exacerbates alcohol-induced hepatic steatosis via suppression of PPARα pathway

X. Dong, Zhaoli Sun, G. Hou, 2021, Cell Death & Disease.

Persistent mTORC1 activation via Depdc5 deletion results in spontaneous hepatocellular carcinoma but does not exacerbate carcinogen- and high-fat diet-induced hepatic carcinogenesis in mice.

Honghui Ma, Rong Huang, Lin Xu, 2021, Biochemical and biophysical research communications.

Sirtuin 6 maintains epithelial STAT6 activity to support intestinal tuft cell development and type 2 immunity

K. Ren, C. Vakoc, Honghui Ma, 2022, Nature Communications.

Epithelial STAT6 O-GlcNAcylation drives a concerted anti-helminth alarmin response dependent on tuft cell hyperplasia and Gasdermin C.

A. Burlingame, K. Hogquist, K. Ren, 2022, Immunity.

A novel PDIP1-related protein, KCTD10, that interacts with proliferating cell nuclear antigen and DNA polymerase delta.

Xiaoxiao Hu, Jianlin Zhou, K. Ren, 2005, Biochimica et biophysica acta.

Glucose metabolic abnormality is associated with defective mineral homeostasis in skeletal disorder mouse model

Xiang Gao, Xiwen Xiong, Jianghuan Zou, 2015, Science China Life Sciences.

αSMA-Cre-mediated Ogt deletion leads to heart failure and vascular smooth muscle cell dysfunction in mice.

Honghui Ma, Xiulong Wang, Dongxu Li, 2022, Biochemical and biophysical research communications.

Identification of a novel point mutation of mouse Atp2b2 induced by N-ethyl-N-nitrosourea mutagenesis.

Xiang Gao, Xiwen Xiong, Zixing Wang, 2011, Experimental animals.

Sestrin 3 Protein Enhances Hepatic Insulin Sensitivity by Direct Activation of the mTORC2-Akt Signaling

S. Liangpunsakul, Xiwen Xiong, Rongya Tao, 2014, Diabetes.

Intestinal Epithelial STAT6 Activation Rescues the Defective Anti-Helminth Responses Caused by Ogt Deletion

Lin Xu, Chenyan Yang, Qingzhi Wang, 2022, International journal of molecular sciences.

Deletion of Hepatic FoxO1/3/4 Genes in Mice Significantly Impacts on Glucose Metabolism through Downregulation of Gluconeogenesis and Upregulation of Glycolysis

Ronald A. DePinho, R. DePinho, Xiwen Xiong, 2013, PloS one.

Deficiency in intestinal epithelial O‐GlcNAcylation predisposes to gut inflammation

Y. Nie, K. Ren, Zan Huang, 2018, EMBO molecular medicine.

Cloning of two rat PDIP1 related genes and their interactions with proliferating cell nuclear antigen.

Xiaoxiao Hu, Jian Zhang, Xiang Hu, 2005, Journal of experimental zoology. Part A, Comparative experimental biology.

Genetic Inactivation of Pyruvate Dehydrogenase Kinases Improves Hepatic Insulin Resistance Induced Diabetes

Robert A. Harris, M. White, X. Dong, 2013, PloS one.

Flavonoids of Rosa roxburghii Tratt Exhibit Anti‐Apoptosis Properties by Regulating PARP‐1/AIF

Wancai Yang, Lijuan Wang, Xiwen Xiong, 2017, Journal of cellular biochemistry.

Hepatic SREBP-2 and cholesterol biosynthesis are regulated by FoxO3 and Sirt6[S]

R. DePinho, C. Deng, Xiwen Xiong, 2013, Journal of Lipid Research.

Protein O-GlcNAc Modification Links Dietary and Gut Microbial Cues to the Differentiation of Enteroendocrine L Cells

Xiaoyong Yang, E. Alejandro, K. Ren, 2020, Cell reports.

NAMPT overexpression alleviates alcohol-induced hepatic steatosis in mice

Lin Xu, Qingzhi Wang, Xiwen Xiong, 2019, PloS one.

Sirtuin 6 ameliorates alcohol-induced liver injury by reducing endoplasmic reticulum stress in mice.

Lin Xu, Chenyan Yang, Xinge Zhang, 2021, Biochemical and biophysical research communications.

Glucose metabolic abnormality is associated with defective mineral homeostasis in skeletal disorder mouse model

Xiang Gao, Xiwen Xiong, Jianghuan Zou, 2015, Science China Life Sciences.

The inhibitory effect of ethanol on Sestrin3 in the pathogenesis of ethanol-induced liver injury.

S. Liangpunsakul, Xiwen Xiong, Rongya Tao, 2014, American journal of physiology. Gastrointestinal and liver physiology.

The inhibitory effect of ethanol on Sestrin3 in the pathogenesis of ethanol-induced liver injury.

S. Liangpunsakul, Xiwen Xiong, Rongya Tao, 2014, American journal of physiology. Gastrointestinal and liver physiology.

C. Deng, Xiwen Xiong, Rongya Tao, 2013, The Journal of Biological Chemistry.

Fabp4-Cre-mediated Sirt6 deletion impairs adipose tissue function and metabolic homeostasis in mice.

Xiwen Xiong, Yang Zhang, Rui Fan, 2017, The Journal of endocrinology.