A. Blas-García

发表

Understanding the implication of autophagy in the activation of hepatic stellate cells in liver fibrosis: are we there yet?

J. Esplugues, V. Víctor, Federico Lucantoni, 2021, The Journal of pathology.

Differential effects of anti-TNF-α and anti-IL-12/23 agents on human leukocyte-endothelial cell interactions.

J. Esplugues, C. de Pablo, C. Ríos-Navarro, 2015, European journal of pharmacology.

Role of p62/SQSTM1 beyond autophagy: a lesson learned from drug‐induced toxicity in vitro

J. Esplugues, N. Apostolova, Ángela B Moragrega, 2018, British journal of pharmacology.

Abacavir Induces Arterial Thrombosis in a Murine Model

J. Esplugues, I. Anduj́ar, A. Blas-García, 2018, The Journal of infectious diseases.

Lon protease: a novel mitochondrial matrix protein in the interconnection between drug‐induced mitochondrial dysfunction and endoplasmic reticulum stress

J. Esplugues, L. Gibellini, N. Apostolova, 2017, British journal of pharmacology.

Toxicological properties of two fluorescent carbon quantum dots with onion ring morphology and their usefulness as bioimaging agents

H. García, J. Herance, V. Víctor, 2016 .

The purine analogues abacavir and didanosine increase acetaminophen-induced hepatotoxicity by enhancing mitochondrial dysfunction.

J. Esplugues, V. Víctor, N. Apostolova, 2016, The Journal of antimicrobial chemotherapy.

Compromising mitochondrial function with the antiretroviral drug efavirenz induces cell survival‐promoting autophagy

J. Esplugues, N. Apostolova, A. Blas-García, 2011, Hepatology.

Efavirenz alters mitochondrial respiratory function in cultured neuron and glial cell lines.

J. Esplugues, N. Apostolova, A. Blas-García, 2015, The Journal of antimicrobial chemotherapy.

Lack of mitochondrial toxicity of darunavir, raltegravir and rilpivirine in neurons and hepatocytes: a comparison with efavirenz.

J. Esplugues, E. Martinez, N. Apostolova, 2014, The Journal of antimicrobial chemotherapy.

Profile of stress and toxicity gene expression in human hepatic cells treated with Efavirenz.

J. Esplugues, N. Apostolova, A. Blas-García, 2012, Antiviral research.

Mitochondrial interference by anti-HIV drugs: mechanisms beyond Pol-γ inhibition.

J. Esplugues, N. Apostolova, A. Blas-García, 2011, Trends in pharmacological sciences.

Macrophages Modulate Hepatic Injury Involving NLRP3 Inflammasome: The Example of Efavirenz

J. Esplugues, M. Pinti, N. Apostolova, 2022, Biomedicines.

Implication of autophagy in the antifibrogenic effect of Rilpivirine: when more is less

J. Esplugues, Federico Lucantoni, N. Apostolova, 2022, Cell death & disease.

Mitochondria sentencing about cellular life and death: a matter of oxidative stress.

J. Esplugues, N. Apostolova, A. Blas-García, 2011, Current pharmaceutical design.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

ER stress in human hepatic cells treated with Efavirenz: mitochondria again.

J. Esplugues, V. Víctor, N. Apostolova, 2013, Journal of hepatology.

Tenofovir-induced toxicity in renal proximal tubular epithelial cells: involvement of mitochondria

J. Górriz, J. Peris, L. Milián, 2017, AIDS.

Is Autophagy Altered in the Leukocytes of Type 2 Diabetic Patients?

A. Jover, V. Víctor, N. Diaz-Morales, 2015, Antioxidants & redox signaling.

Mitochondrial (dys)function – a factor underlying the variability of efavirenz‐induced hepatotoxicity?

V. Víctor, N. Apostolova, A. Blas-García, 2015, British journal of pharmacology.

Metabolic-associated fatty liver disease: from simple steatosis towards liver cirrhosis and potential complications. Proceedings of the Third Translational Hepatology Meeting, endorsed by the Spanish Association for the Study of the Liver (AEEH)

J. Falcón-Pérez, J. Ampuero, M. Fernández-Barrena, 2022, Gastroenterologia y hepatologia.

DIFFERENTIAL EFFECTS OF BIOLOGICS ON PSORIASIS-RELATED VASCULAR INFLAMMATION AND RISK OF THROMBOSIS.

J. Esplugues, S. Rovira-Llopis, A. Blas-García, 2020, The Journal of investigative dermatology.

NNRTI and Liver Damage: Evidence of Their Association and the Mechanisms Involved

J. Esplugues, J. Tosca, N. Apostolova, 2021, Cells.

Mitochondrial toxicity in HAART: an overview of in vitro evidence.

J. Esplugues, N. Apostolova, A. Blas-García, 2011, Current pharmaceutical design.

Efavirenz and the CNS: what we already know and questions that need to be answered.

J. Esplugues, N. Apostolova, A. Blas-García, 2015, The Journal of antimicrobial chemotherapy.

Efavirenz: What is known about the cellular mechanisms responsible for its adverse effects

J. Esplugues, N. Apostolova, A. Blas-García, 2017, European journal of pharmacology.

Future Perspectives in NNRTI-Based Therapy: Bases for Understanding Their Toxicity

J. Esplugues, N. Apostolova, A. Blas-García, 2011 .

UEG Week 2019 Poster Presentations

N. Apostolova, A. Blas-García, A. Martí-Rodrigo, 2019, United European gastroenterology journal.

Neuronal bioenergetics and acute mitochondrial dysfunction: a clue to understanding the central nervous system side effects of efavirenz.

J. Esplugues, N. Apostolova, A. Blas-García, 2014, The Journal of infectious diseases.

Apoptosis of Hepatocytes: Relevance for HIV-Infected Patients under Treatment

J. Esplugues, A. Cossarizza, N. Apostolova, 2021, Cells.

Implication of autophagy in the antifibrogenic effect of Rilpivirine: when more is less

J. Esplugues, Federico Lucantoni, N. Apostolova, 2022, Cell Death & Disease.

Rilpivirine attenuates liver fibrosis through selective STAT1-mediated apoptosis in hepatic stellate cells

J. Esplugues, F. García-García, J. Gracia‐Sancho, 2019, Gut.

Enhanced oxidative stress and increased mitochondrial mass during Efavirenz‐induced apoptosis in human hepatic cells

N. Apostolova, A. Blas-García, J. Esplugues, 2010, British journal of pharmacology.

Protein tyrosine phosphatase 1b deficiency protects against hepatic fibrosis by modulating nadph oxidases

P. Rada, Á. Valverde, V. Pardo, 2019, Redox biology.

Metabolomics of the effect of AMPK activation by AICAR on human umbilical vein endothelial cells.

D. Monleón, N. Apostolova, J. M. Morales, 2011, International journal of molecular medicine.

Mitophagy in human astrocytes treated with the antiretroviral drug Efavirenz: Lack of evidence or evidence of the lack.

J. Esplugues, J. M. Fuentes, V. Víctor, 2019, Antiviral research.

Gastric Antisecretory Drugs Induce Leukocyte-Endothelial Cell Interactions through Gastrin Release and Activation of CCK-2 Receptors

S. Calatayud, A. Blas-García, Á. Álvarez, 2007, Journal of Pharmacology and Experimental Therapeutics.

Oxidative stress and mitochondrial impairment after treatment with anti-HIV drugs: clinical implications.

J. Esplugues, N. Apostolova, A. Blas-García, 2011, Current pharmaceutical design.

Twenty years of HIV-1 non-nucleoside reverse transcriptase inhibitors: time to reevaluate their toxicity.

N. Apostolova, A. Blas-García, J. Esplugues, 2011, Current Medicinal Chemistry.

The pivotal role of nitric oxide: effects on the nervous and immune systems.

J. Herance, V. Víctor, A. Hernández-Mijares, 2014, Current pharmaceutical design.

Transcriptome-based repurposing of apigenin as a potential anti-fibrotic agent targeting hepatic stellate cells

J. Dudley, S. Friedman, Y. Hoshida, 2017, Scientific Reports.

Inhibition of mitochondrial function by efavirenz increases lipid content in hepatic cells

J. Esplugues, D. Monleón, V. Víctor, 2010, Hepatology.

J. Esplugues, N. Apostolova, A. Gruevska, 2020, Antiviral research.

Oxidative and endoplasmic reticulum stress is impaired in leukocytes from metabolically unhealthy vs healthy obese individuals

C. Morillas, V. Víctor, N. Diaz-Morales, 2017, International Journal of Obesity.

Involvement of nitric oxide in the mitochondrial action of efavirenz: a differential effect on neurons and glial cells.

J. Esplugues, N. Apostolova, A. Blas-García, 2015, The Journal of infectious diseases.

Down-Regulation of the Longevity-Associated Protein SIRT1 in Peripheral Blood Mononuclear Cells of Treated HIV Patients

J. Esplugues, N. Apostolova, A. Gruevska, 2022, Cells.

Novel Therapeutic Approaches to Liver Fibrosis Based on Targeting Oxidative Stress

N. Apostolova, A. Blas-García, 2023, Antioxidants.

Benefits of rilpivirine for liver stiffness in HIV/HCV-coinfected patients.

J. Esplugues, J. González-García, A. Blas-García, 2022, Enfermedades infecciosas y microbiologia clinica.

Anti-inflammatory and immunomodulating effects of rilpivirine: Relevance for the therapeutics of chronic liver disease.

J. Tosca, N. Apostolova, A. Gruevska, 2023, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

ER stress in human hepatic cells treated with Efavirenz: mitochondria again.

J. Esplugues, N. Apostolova, M. Barrachina, 2013, Journal of hepatology.

Compromising mitochondrial function with the antiretroviral drug efavirenz induces cell survival‐promoting autophagy

J. Esplugues, N. Apostolova, A. Blas-García, 2011, Hepatology.

J. Falcón-Pérez, J. Ampuero, M. Fernández-Barrena, 2022, Gastroenterología y Hepatología.

Rilpivirine Activates STAT1 in Non-Parenchymal Cells to Regulate Liver Injury in People Living with HIV and MASLD

N. Apostolova, A. Blas-García, C. Busca, 2024, Biomedicines.

Interference with mitochondrial function as part of the antifibrogenic effect of Rilpivirine: A step towards novel targets in hepatic stellate cell activation.

Federico Lucantoni, E. Muñoz-Forner, N. Apostolova, 2024, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Modulating Myeloid Immune Cell Migration Using Multivalently Presented Monosaccharide Ligands for Advanced Immunotherapy

F. Tacke, C. Trautwein, J. Dernedde, 2019, Advanced Therapeutics.