Lian-Sheng Li

Allele-specific inhibitors inactivate mutant KRAS G12C by a trapping mechanism

Neal Rosen, N. Rosen, P. Lito, 2016, Science.

The reactivity-driven biochemical mechanism of covalent KRASG12C inhibitors

Yi Liu, Jun Feng, Pingda Ren, 2018, Nature Structural & Molecular Biology.

Selective Inhibition of Oncogenic KRAS Output with Small Molecules Targeting the Inactive State.

Yi Liu, Jun Feng, Pingda Ren, 2016, Cancer discovery.

PI3K-δ and PI3K-γ inhibition by IPI-145 abrogates immune responses and suppresses activity in autoimmune and inflammatory disease models.

Bonnie Tillotson, James R. Porter, Pingda Ren, 2013, Chemistry & biology.