Rasmus Hansen

Allele-specific inhibitors inactivate mutant KRAS G12C by a trapping mechanism

Neal Rosen, N. Rosen, P. Lito, 2016, Science.

The reactivity-driven biochemical mechanism of covalent KRASG12C inhibitors

Yi Liu, Jun Feng, Pingda Ren, 2018, Nature Structural & Molecular Biology.

Selective Inhibition of Oncogenic KRAS Output with Small Molecules Targeting the Inactive State.

Yi Liu, Jun Feng, Pingda Ren, 2016, Cancer discovery.

An Internally Controlled Quantitative Target Occupancy Assay for Covalent Inhibitors

Yi Liu, P. Zarrinkar, M. R. Janes, 2018, Scientific Reports.