J. von Schnurbein

发表

Methylphenidate in children with monogenic obesity due to LEPR or MC4R deficiency improves feeling of satiety and reduces BMI‐SDS—A case series

J. Hebebrand, M. Wabitsch, H. Bode, 2020, Pediatric obesity.

Leptin Replacement Reestablishes Brain Insulin Action in the Hypothalamus in Congenital Leptin Deficiency

R. Veit, H. Preissl, J. Machann, 2018, Diabetes Care.

Leptin therapy in a congenital leptin-deficient patient leads to acute and long-term changes in homeostatic, reward, and food-related brain areas.

H. Preissl, M. Wabitsch, S. Farooqi, 2011, The Journal of clinical endocrinology and metabolism.

European lipodystrophy registry: background and structure

R. Hennekam, G. Nagel, F. Santini, 2020, Orphanet Journal of Rare Diseases.

Sleep and glycemic control in adolescents with type 1 diabetes

M. Wabitsch, C. Vetter, T. Roenneberg, 2018, Pediatric diabetes.

Lipodystrophy as a Late Effect after Stem Cell Transplantation

A. Schulz, G. Ceccarini, M. Wabitsch, 2021, Journal of clinical medicine.

Genetic Obesity in Children: Overview of Possible Diagnoses with a Focus on SH2B1 Deletion

M. Schirmer, R. Siebert, T. Reinehr, 2021, Hormone Research in Paediatrics.

Serum IGF1 and linear growth in children with congenital leptin deficiency before and after leptin substitution

S. Shalitin, F. Santini, M. Wabitsch, 2021, International Journal of Obesity.

Functional and Phenotypic Characteristics of Human Leptin Receptor Mutations

P. Fischer-Posovszky, M. Wabitsch, P. Gierschik, 2018, Journal of the Endocrine Society.

Reference Values and Early Determinants of Intra-Abdominal Fat Mass in Primary School Children

J. Klenk, J. Steinacker, S. Weiland, 2011, Hormone Research in Paediatrics.

A fresh look to the phenotype in mono-allelic likely pathogenic variants of the leptin and the leptin receptor gene

R. Siebert, P. Fischer-Posovszky, M. Wabitsch, 2021, Molecular and Cellular Pediatrics.

Monogenic forms of childhood obesity due to mutations in the leptin gene

P. Fischer-Posovszky, M. Wabitsch, K. Debatin, 2014, Molecular and Cellular Pediatrics.

Diagnostic and therapeutic odyssey of two patients with compound heterozygous leptin receptor deficiency

M. Wabitsch, S. Zorn, C. Denzer, 2020, Molecular and Cellular Pediatrics.

Rapid Improvement of Hepatic Steatosis after Initiation of Leptin Substitution in a Leptin-Deficient Girl

J. Machann, M. Wabitsch, S. Farooqi, 2013, Hormone Research in Paediatrics.

Severe Early-Onset Obesity Due to Bioinactive Leptin Caused by a p.N103K Mutation in the Leptin Gene

Vanisha Mistry, P. Fischer-Posovszky, I. Farooqi, 2015, The Journal of clinical endocrinology and metabolism.

A new missense mutation in the leptin gene causes mild obesity and hypogonadism without affecting T cell responsiveness.

J. Kassubek, P. Fischer-Posovszky, M. Wabitsch, 2010, The Journal of clinical endocrinology and metabolism.

Leptin Substitution Results in the Induction of Menstrual Cycles in an Adolescent with Leptin Deficiency and Hypogonadotropic Hypogonadism

I. Farooqi, M. Wabitsch, K. Debatin, 2012, Hormone Research in Paediatrics.

Measurement of immunofunctional leptin to detect and monitor patients with functional leptin deficiency

P. Fischer-Posovszky, M. Wabitsch, M. Ranke, 2016, European journal of endocrinology.

Lower Circulating Leptin Levels Are Related to Non-Alcoholic Fatty Liver Disease in Children With Obesity

W. Kratzer, C. Denzer, S. Brandt, 2022, Frontiers in Endocrinology.

Novel Homozygous AIRE Mutation in a German Patient with Severe APECED

M. Wabitsch, K. Debatin, J. von Schnurbein, 2008, Journal of pediatric endocrinology & metabolism : JPEM.

Loss of enteroendocrine cells in autoimmune-polyendocrine-candidiasis-ectodermal-dystrophy (APECED) syndrome with gastrointestinal dysfunction.

A. Schulz, M. Wabitsch, T. Barth, 2012, The Journal of clinical endocrinology and metabolism.

First Account of Psychological Changes Perceived by a Female with Congenital Leptin Deficiency upon Treatment with Metreleptin

J. Hebebrand, S. Zorn, J. Antel, 2022, Obesity Facts.

Sonographically Assessed Intra-Abdominal Fat

J. von Schnurbein, 2011, Hormone Research in Paediatrics.

Relative leptin deficiency in children with severe early-onset obesity (SEOO) – results of the Early-onset Obesity and Leptin – German-Polish Study (EOL-GPS)

A. Mazur, M. Wabitsch, M. Ranke, 2020, Journal of pediatric endocrinology & metabolism : JPEM.

The Diagnosis and Management of Lipodystrophy Syndromes: A Multi-Society Practice Guideline

D. Dunger, N. Patni, M. Wabitsch, 2016, The Journal of clinical endocrinology and metabolism.

Long-Term Stabilization Effects of Leptin on Brain Functions in a Leptin-Deficient Patient

H. Preissl, M. Wabitsch, S. Farooqi, 2013, PloS one.

A Novel Syndrome of Generalized Lipodystrophy Associated With Pilocytic Astrocytoma.

D. Rakheja, N. Patni, M. Wabitsch, 2015, The Journal of clinical endocrinology and metabolism.

R. Holle, J. Hebebrand, A. Scherag, 2020, Health and Quality of Life Outcomes.

Do adolescents with extreme obesity differ according to previous treatment seeking behavior? The Youth with Extreme obesity Study (YES) cohort

R. Holle, J. Hebebrand, A. Scherag, 2018, International Journal of Obesity.

Quality of life outcomes in two phase 3 trials of setmelanotide in patients with obesity due to LEPR or POMC deficiency

K. Clément, A. Gnanasakthy, C. Poitou, 2022, Orphanet Journal of Rare Diseases.

Leptin Is Not Essential for Obesity-Associated Hypertension

P. Fischer-Posovszky, M. Wabitsch, S. Mahmood, 2019, Obesity Facts.

Positive effect of leptin substitution on mood and behaviour in patients with congenital leptin deficiency

J. Hebebrand, S. Mahmood, S. Brandt, 2023, Pediatric obesity.

The Metreleptin Effectiveness and Safety Registry (MEASuRE): concept, design and challenges

M. Haymond, C. Musso, J. von Schnurbein, 2023, Orphanet Journal of Rare Diseases.

Rare Antagonistic Leptin Variants and Severe, Early-Onset Obesity.

S. Savvides, P. Fischer-Posovszky, I. Farooqi, 2023, The New England journal of medicine.

The Diagnosis and Management of Lipodystrophy Syndromes: A Multi-Society Practice Guideline

D. Dunger, N. Patni, M. Wabitsch, 2016, The Journal of clinical endocrinology and metabolism.

A new missense mutation in the leptin gene causes mild obesity and hypogonadism without affecting T cell responsiveness.

J. Kassubek, P. Fischer-Posovszky, M. Wabitsch, 2010, The Journal of clinical endocrinology and metabolism.

Efficacy and safety of setmelanotide, an MC4R agonist, in individuals with severe obesity due to LEPR or POMC deficiency: single-arm, open-label, multicentre, phase 3 trials.

W. Chung, K. Clément, I. Farooqi, 2020, The lancet. Diabetes & endocrinology.

Changes in Satiety Hormones in Response to Leptin Treatment in a Patient with Leptin Deficiency

M. Wabitsch, C. Roth, Clinton T. Elfers, 2018, Hormone Research in Paediatrics.